DK164785C - 5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner, deres fremstilling og deres anvendelse til fremstilling af antipedressive midler - Google Patents

5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner, deres fremstilling og deres anvendelse til fremstilling af antipedressive midler

Info

Publication number: DK164785C
Authority: DK; Denmark
Prior art keywords: preparation; antipedressive; thiones; triazol; dialkyl
Prior art date: 1985-10-29

Application number

DK514886A

Other languages

English (en)

Other versions

DK514886A (da

DK514886D0 (da

DK164785B (da

Inventor

John M Kane

Francis P Miller

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-29

Filing date

1986-10-28

Publication date

1992-12-28

1986-10-28 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1986-10-28 Publication of DK514886D0 publication Critical patent/DK514886D0/da

1987-04-30 Publication of DK514886A publication Critical patent/DK514886A/da

1992-08-17 Publication of DK164785B publication Critical patent/DK164785B/da

1992-12-28 Application granted granted Critical

1992-12-28 Publication of DK164785C publication Critical patent/DK164785C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK514886A 1985-10-29 1986-10-28 5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner, deres fremstilling og deres anvendelse til fremstilling af antipedressive midler DK164785C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US79235985A	1985-10-29	1985-10-29
US79235985		1985-10-29
US80761385A	1985-12-11	1985-12-11
US80761385		1985-12-11

Publications (4)

Publication Number	Publication Date
DK514886D0 DK514886D0 (da)	1986-10-28
DK514886A DK514886A (da)	1987-04-30
DK164785B DK164785B (da)	1992-08-17
DK164785C true DK164785C (da)	1992-12-28

Family

ID=27121269

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK514886A DK164785C (da)	1985-10-29	1986-10-28	5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner, deres fremstilling og deres anvendelse til fremstilling af antipedressive midler

Country Status (19)

Country	Link
EP (1)	EP0221485B1 (da)
JP (1)	JPH07116162B2 (da)
KR (1)	KR900003879B1 (da)
CN (1)	CN1014993B (da)
AR (1)	AR243171A1 (da)
AU (1)	AU587646B2 (da)
CA (2)	CA1284997C (da)
DE (1)	DE3676632D1 (da)
DK (1)	DK164785C (da)
ES (1)	ES2031449T3 (da)
FI (1)	FI89047C (da)
GR (1)	GR3001246T3 (da)
HU (1)	HU196191B (da)
IE (1)	IE58969B1 (da)
IL (1)	IL80434A (da)
NO (1)	NO165542C (da)
NZ (1)	NZ218087A (da)
PH (2)	PH22377A (da)
PT (1)	PT83636B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR243169A1 (es) *	1985-10-29	1993-07-30	Merrell Pharma Inc	Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas.
JP2593084B2 (ja) *	1986-12-19	1997-03-19	メレルダウファーマスーティカルズインコーポレーテッド	５−アリールー３ｈ−１，２，４−トリアゾールー３−オン類の神経変性障害の処置への用途
JP2542880B2 (ja) *	1986-12-19	1996-10-09	メレルダウファーマスーティカルズインコーポレーテッド	５−アリ―ル−３ｈ−１，２，４，−トリアゾ―ル−３−オン類の抗痙攣剤としての用途
EP0280867A1 (en) *	1987-01-27	1988-09-07	Merrell Dow Pharmaceuticals Inc.	Process for the preparation of 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones
US4847276A (en) *	1988-09-06	1989-07-11	Merrell Dow Pharmaceuticals Inc.	Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione
AU679130B2 (en) *	1993-10-29	1997-06-19	Aventis Inc.	3-aryl-4-alkyl and 4,5-dialkyl-4H-1,2,4-triazoles useful as memory enhancers
CA2193800C (en) *	1994-07-07	1999-03-16	Sandra K. Stolz-Dunn	Process for the preparation of 5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR243169A1 (es) *	1985-10-29	1993-07-30	Merrell Pharma Inc	Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas.
DK570987A (da) *	1986-12-01	1988-06-02	Hoffmann La Roche	Oxadiazol-, thiadiazol- og triazolforbindelser

1986
- 1986-10-22 AR AR86305652A patent/AR243171A1/es active
- 1986-10-24 AU AU64386/86A patent/AU587646B2/en not_active Ceased
- 1986-10-24 CA CA000521330A patent/CA1284997C/en not_active Expired - Lifetime
- 1986-10-24 PH PH34414A patent/PH22377A/en unknown
- 1986-10-27 DE DE8686114874T patent/DE3676632D1/de not_active Expired - Fee Related
- 1986-10-27 ES ES198686114874T patent/ES2031449T3/es not_active Expired - Lifetime
- 1986-10-27 EP EP86114874A patent/EP0221485B1/en not_active Expired - Lifetime
- 1986-10-28 KR KR1019860009007A patent/KR900003879B1/ko not_active IP Right Cessation
- 1986-10-28 CN CN86106880A patent/CN1014993B/zh not_active Expired
- 1986-10-28 FI FI864377A patent/FI89047C/fi not_active IP Right Cessation
- 1986-10-28 NZ NZ218087A patent/NZ218087A/xx unknown
- 1986-10-28 IE IE283286A patent/IE58969B1/en not_active IP Right Cessation
- 1986-10-28 HU HU864526A patent/HU196191B/hu not_active IP Right Cessation
- 1986-10-28 JP JP61254829A patent/JPH07116162B2/ja not_active Expired - Lifetime
- 1986-10-28 DK DK514886A patent/DK164785C/da active
- 1986-10-28 IL IL80434A patent/IL80434A/xx not_active IP Right Cessation
- 1986-10-28 PT PT83636A patent/PT83636B/pt not_active IP Right Cessation
- 1986-10-28 NO NO864306A patent/NO165542C/no not_active IP Right Cessation
1987
- 1987-10-08 PH PH35910A patent/PH23275A/en unknown
1990
- 1990-08-07 CA CA000615808A patent/CA1301655C/en not_active Expired - Lifetime
- 1990-12-28 GR GR90401022T patent/GR3001246T3/el unknown

Also Published As

Publication number	Publication date
IE862832L (en)	1987-04-29
JPS62106085A (ja)	1987-05-16
EP0221485B1 (en)	1990-12-27
PT83636A (en)	1986-11-01
NO864306D0 (no)	1986-10-28
NZ218087A (en)	1989-05-29
CA1301655C (en)	1992-05-26
CN86106880A (zh)	1987-06-10
DK514886A (da)	1987-04-30
DK514886D0 (da)	1986-10-28
NO165542B (no)	1990-11-19
IL80434A0 (en)	1987-01-30
NO165542C (no)	1991-02-27
FI89047C (fi)	1993-08-10
PH22377A (en)	1988-08-12
JPH07116162B2 (ja)	1995-12-13
IL80434A (en)	1991-01-31
AU6438686A (en)	1987-04-30
FI864377A0 (fi)	1986-10-28
HU196191B (en)	1988-10-28
PH23275A (en)	1989-06-23
IE58969B1 (en)	1993-12-01
CN1014993B (zh)	1991-12-04
AU587646B2 (en)	1989-08-24
KR900003879B1 (ko)	1990-06-04
CA1284997C (en)	1991-06-18
FI89047B (fi)	1993-04-30
DE3676632D1 (de)	1991-02-07
AR243171A1 (es)	1993-07-30
FI864377A (fi)	1987-04-30
ES2031449T3 (es)	1992-12-16
PT83636B (pt)	1988-10-14
GR3001246T3 (en)	1992-07-30
KR870004006A (ko)	1987-05-06
DK164785B (da)	1992-08-17
HUT45030A (en)	1988-05-30
NO864306L (no)	1987-04-30
EP0221485A1 (en)	1987-05-13

Publication	Publication Date	Title
DK543386A (da)	1987-05-15	Thienooxazinoner deres fremstilling og anvendelse
DK546186A (da)	1987-05-17	Substituerede benzylethere, deres fremstilling og anvendelse
DK129386A (da)	1986-09-22	Iodpropargylethere, deres fremstilling og anvendelse
NO864378D0 (no)	1986-11-03	Antimikrobielle midler og fremgangsmaate for deres fremstilling.
DK519586A (da)	1987-05-01	1-aryl-4-nitro-pyrazoler, deres fremstilling og anvendelse
DK387587D0 (da)	1987-07-24	1,4-benzodiazepiner, deres fremstilling og anvendelse
DK573385D0 (da)	1985-12-11	2,4-diaminopyrimidiner, deres fremstilling og anvendelse
DK164785C (da)	1992-12-28	5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner, deres fremstilling og deres anvendelse til fremstilling af antipedressive midler
DK380286A (da)	1987-02-11	Sulfonamider, deres fremstilling og anvendelse
DK393485D0 (da)	1985-08-29	1,4-dihydropyridiner, deres fremstilling og anvendelse
DK295785D0 (da)	1985-06-28	1,8-diacyloxy-10-acyl-anthroner, deres fremstilling og anvendelse
DK396886D0 (da)	1986-08-20	Gem-dihalogen-1,8-diamino-4-azaoctaner, deres fremstilling og anvendelse
DK617886D0 (da)	1986-12-19	1-aryl-pyrazoler, deres fremstilling og anvendelse
DK377786D0 (da)	1986-08-07	1-aryl-5-hydrazino-pyrazoler, deres fremstilling og anvendelse
DK538385A (da)	1986-05-28	1,4-dihydropyridiner, deres fremstilling og anvendelse
DK675687D0 (da)	1987-12-21	Substituerede n-methylisoxazolidiner, deres fremstilling og anvendelse
DK8887D0 (da)	1987-01-08	Substituerede 1,3,5-oxadiazin-2-oner samt deres fremstilling og anvendelse
DK447986A (da)	1987-03-20	2-aryl-4,5,6,7-tetrahydroisoindolinoner, deres fremstilling og anvendelse som herbicider
DK393986D0 (da)	1986-08-19	Lactamamider, deres fremstilling og anvendelse
DK361185A (da)	1986-02-10	2-aminoalkyl-2-penem-forbindelser samt deres fremstilling og anvendelse
DK195086D0 (da)	1986-04-29	Substituerede azolylmethylethere, deres fremstilling og anvendelse somfungicide midler
DK451486D0 (da)	1986-09-22	Alkenylazoler, deres fremstilling og anvendelse
DK514686A (da)	1987-04-30	5-naphthyl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner og tautomer deraf, deres fremstilling og anvendelse som antidepressive midler
DK564986A (da)	1987-05-27	Thienylurinstofderivater, deres fremstilling og anvendelse
DK620688D0 (da)	1988-11-08	Quinoxalinforbindelser, deres fremstilling og anvendelse