PT74838B - Process for preparing 1,5-substituted isoquinoline derivatives - Google Patents
Process for preparing 1,5-substituted isoquinoline derivativesInfo
- Publication number
- PT74838B PT74838B PT74838A PT7483882A PT74838B PT 74838 B PT74838 B PT 74838B PT 74838 A PT74838 A PT 74838A PT 7483882 A PT7483882 A PT 7483882A PT 74838 B PT74838 B PT 74838B
- Authority
- PT
- Portugal
- Prior art keywords
- preparing
- isoquinoline derivatives
- substituted isoquinoline
- substituted
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26054781A | 1981-05-04 | 1981-05-04 | |
US06/329,789 US4473501A (en) | 1981-05-04 | 1981-12-11 | Dihydro azino isoquinolines |
Publications (2)
Publication Number | Publication Date |
---|---|
PT74838A PT74838A (en) | 1982-06-01 |
PT74838B true PT74838B (en) | 1983-12-07 |
Family
ID=26948062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT74838A PT74838B (en) | 1981-05-04 | 1982-05-03 | Process for preparing 1,5-substituted isoquinoline derivatives |
Country Status (7)
Country | Link |
---|---|
US (1) | US4473501A (pt) |
EP (1) | EP0064294A1 (pt) |
AU (1) | AU8321782A (pt) |
DK (1) | DK198182A (pt) |
ES (1) | ES511914A0 (pt) |
NO (1) | NO821458L (pt) |
PT (1) | PT74838B (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60237070A (ja) * | 1984-05-08 | 1985-11-25 | Nisshin Flour Milling Co Ltd | 光学活性イソカルボスチリル誘導体の製法 |
SE8801518D0 (sv) * | 1988-04-22 | 1988-04-22 | Astra Pharma Prod | A novel process |
TW575567B (en) * | 1998-10-23 | 2004-02-11 | Akzo Nobel Nv | Serine protease inhibitor |
AU2002367959A1 (en) * | 2001-10-18 | 2003-12-31 | Michigan State University | Process for the preparation of oxazolidinones and method of use thereof |
US7094789B2 (en) * | 2002-07-22 | 2006-08-22 | Asahi Kasei Pharma Corporation | 5-substituted isoquinoline derivatives |
US7998992B2 (en) | 2007-03-30 | 2011-08-16 | Institute Of Medicinal Molecular Design, Inc. | Oxazolidinone derivative having inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA536744A (en) * | 1957-02-05 | Druey Jean | Isoquinoline compounds and process of making same | |
CH307873A (de) * | 1952-05-30 | 1955-06-15 | Ciba Geigy | Verfahren zur Herstellung einer neuen Isochinolinverbindung. |
GB1058822A (en) * | 1963-07-30 | 1967-02-15 | Ici Ltd | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
US4009170A (en) * | 1970-08-10 | 1977-02-22 | Sterling Drug Inc. | 1-Ethoxy-3,4-dihydroisoquindines |
US3753994A (en) * | 1970-08-10 | 1973-08-21 | Sterling Drug Inc | 1,1'-azinobis(1,2,3,4-tetrahydroisoquinolines) |
US3946009A (en) * | 1972-05-05 | 1976-03-23 | Merck Sharp & Dohme (I.A.) Corporation | 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines |
US4115575A (en) * | 1973-02-20 | 1978-09-19 | Ciba-Geigy Corporation | 2-(3-Amino-2-hydroxy-propoxy)-pyrazines |
US4073909A (en) * | 1973-10-08 | 1978-02-14 | Sandoz Ltd. | Isoquinoline compounds |
SE431451B (sv) * | 1973-10-24 | 1984-02-06 | Otsuka Pharma Co Ltd | Forfarande for framstellning av 2,3-dihydroxipropoxikinoliner eller -isokinoliner |
JPS538707B2 (pt) * | 1974-02-05 | 1978-03-31 | ||
JPS5318032B2 (pt) * | 1974-03-04 | 1978-06-13 | ||
DE2639718C2 (de) * | 1976-09-03 | 1987-03-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel |
DE2644833A1 (de) * | 1976-10-05 | 1978-04-20 | Boehringer Sohn Ingelheim | Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung |
-
1981
- 1981-12-11 US US06/329,789 patent/US4473501A/en not_active Expired - Lifetime
-
1982
- 1982-05-03 PT PT74838A patent/PT74838B/pt unknown
- 1982-05-03 NO NO821458A patent/NO821458L/no unknown
- 1982-05-03 DK DK198182A patent/DK198182A/da not_active Application Discontinuation
- 1982-05-03 AU AU83217/82A patent/AU8321782A/en not_active Abandoned
- 1982-05-04 EP EP82103812A patent/EP0064294A1/en not_active Withdrawn
- 1982-05-04 ES ES82511914A patent/ES511914A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
PT74838A (en) | 1982-06-01 |
US4473501A (en) | 1984-09-25 |
EP0064294A1 (en) | 1982-11-10 |
ES8401066A1 (es) | 1983-12-01 |
AU8321782A (en) | 1982-11-11 |
ES511914A0 (es) | 1983-12-01 |
NO821458L (no) | 1982-11-05 |
DK198182A (da) | 1982-11-05 |
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