PT727419E - Compostos intermediarios para a preparacao de inibidores da protease retroviral - Google Patents
Compostos intermediarios para a preparacao de inibidores da protease retroviralInfo
- Publication number
- PT727419E PT727419E PT96106301T PT96106301T PT727419E PT 727419 E PT727419 E PT 727419E PT 96106301 T PT96106301 T PT 96106301T PT 96106301 T PT96106301 T PT 96106301T PT 727419 E PT727419 E PT 727419E
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- retroviral protease
- protease inhibitors
- intermediate compounds
- formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 230000001177 retroviral effect Effects 0.000 title abstract 2
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 title 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K38/00—Medicinal preparations containing peptides
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- Chemical & Material Sciences (AREA)
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Hematology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US99811492A | 1992-12-29 | 1992-12-29 | |
US15858793A | 1993-12-02 | 1993-12-02 |
Publications (1)
Publication Number | Publication Date |
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PT727419E true PT727419E (pt) | 2002-08-30 |
Family
ID=26855178
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96106301T PT727419E (pt) | 1992-12-29 | 1993-12-16 | Compostos intermediarios para a preparacao de inibidores da protease retroviral |
PT02079949T PT1302468E (pt) | 1992-12-29 | 1993-12-16 | Processos e intermediários para o fabrico de compostos inibidores de protease retroviral |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT02079949T PT1302468E (pt) | 1992-12-29 | 1993-12-16 | Processos e intermediários para o fabrico de compostos inibidores de protease retroviral |
Country Status (18)
Country | Link |
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US (6) | US5886036A (pt) |
EP (4) | EP0674513B1 (pt) |
JP (6) | JP2637847B2 (pt) |
KR (4) | KR100187613B1 (pt) |
AT (4) | ATE143262T1 (pt) |
AU (3) | AU659575B2 (pt) |
CA (5) | CA2135890C (pt) |
DE (6) | DE69334250D1 (pt) |
DK (4) | DK0674513T3 (pt) |
ES (4) | ES2189721T3 (pt) |
GR (2) | GR950300059T1 (pt) |
HK (3) | HK130697A (pt) |
HU (1) | HU211606A9 (pt) |
IL (5) | IL108126A (pt) |
LU (1) | LU90839I2 (pt) |
NL (1) | NL300060I2 (pt) |
PT (2) | PT727419E (pt) |
WO (1) | WO1994014436A1 (pt) |
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