PT66780B - Procede pour la preparation de derives de l'acide 5-aroil-1,2- dihydro-3h-pirrole /1,2-alpha/ pirrole-1-carboxilique - Google Patents

Procede pour la preparation de derives de l'acide 5-aroil-1,2- dihydro-3h-pirrole /1,2-alpha/ pirrole-1-carboxilique

Info

Publication number: PT66780B
Authority: PT; Portugal
Prior art keywords: pirrole; aroil; dihydro; alpha; preparation
Prior art date: 1976-07-14

Application number

PT66780A

Other languages

English (en)

French (fr)

Portuguese (pt)

Other versions

PT66780A (fr

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-14

Filing date

1977-07-08

Publication date

1978-12-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107410&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT66780(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1977-02-23 Priority claimed from US05/771,286 external-priority patent/US4089969A/en

1977-07-08 Application filed by Syntex Inc filed Critical Syntex Inc

1977-08-01 Publication of PT66780A publication Critical patent/PT66780A/pt

1978-12-18 Publication of PT66780B publication Critical patent/PT66780B/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)

PT66780A 1976-07-14 1977-07-08 Procede pour la preparation de derives de l'acide 5-aroil-1,2- dihydro-3h-pirrole /1,2-alpha/ pirrole-1-carboxilique PT66780B (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US70490976A	1976-07-14	1976-07-14
US05/771,286 US4089969A (en)	1976-07-14	1977-02-23	5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof

Publications (2)

Publication Number	Publication Date
PT66780A PT66780A (fr)	1977-08-01
PT66780B true PT66780B (fr)	1978-12-18

Family

ID=27107410

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT66780A PT66780B (fr)	1976-07-14	1977-07-08	Procede pour la preparation de derives de l'acide 5-aroil-1,2- dihydro-3h-pirrole /1,2-alpha/ pirrole-1-carboxilique

Country Status (27)

Country	Link
JP (1)	JPS539788A (it)
AR (1)	AR224997A1 (it)
CA (1)	CA1102809A (it)
CH (3)	CH641458A5 (it)
CS (1)	CS204954B2 (it)
DE (2)	DE2731678A1 (it)
DK (1)	DK151886C (it)
ES (2)	ES460706A1 (it)
FI (1)	FI63406C (it)
FR (2)	FR2358406A1 (it)
GB (1)	GB1554075A (it)
GR (1)	GR61111B (it)
HK (1)	HK15981A (it)
HU (1)	HU174224B (it)
IE (1)	IE45253B1 (it)
IL (2)	IL52493A (it)
IT (1)	IT1117313B (it)
MX (1)	MX163202B (it)
MY (1)	MY8100357A (it)
NL (2)	NL186318C (it)
NO (1)	NO147564C (it)
NZ (1)	NZ184610A (it)
PL (4)	PL124444B1 (it)
PT (1)	PT66780B (it)
SE (1)	SE434643B (it)
SU (1)	SU695558A3 (it)
YU (1)	YU40816B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4140698A (en) *	1977-07-25	1979-02-20	Syntex (Usa) Inc.	1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
JPS55124633A (en) *	1979-03-19	1980-09-25	Sohachi Takeuchi	Manufacturing method of tubular vessel
US4344943A (en) *	1980-06-09	1982-08-17	Syntex (U.S.A.) Inc.	6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) *	1980-11-21	1982-10-12	Syntex (U.S.A.) Inc.	Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
JPS5910589A (ja) *	1982-06-10	1984-01-20	メルク　エンド　カムパニー　インコーポレーテツド	抗炎症剤および鎮痛剤として新規な５−（ピロ−ル−２−オイル）−１，２−ジヒドロ−３Ｈ−ピロロ〔１，２−ａ〕ピロ−ル誘導体
US4511724A (en) *	1982-06-10	1985-04-16	Merck & Co., Inc.	5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
US4874871A (en) *	1987-03-25	1989-10-17	Syntex (U.S.A.) Inc.	Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds
JPH0739418B2 (ja) *	1987-09-10	1995-05-01	久光製薬株式会社	新規な３−アロイル−６，７−ジヒドロ−５Ｈ−ピロロ〔１，２−ｃ〕イミダゾール−７−カルボン酸誘導体
JP2649168B2 (ja) *	1988-02-25	1997-09-03	久光製薬株式会社	新規な５，６−ジフェニル−１，２−ジヒドロ−３Ｈ−ピロロ［１，２−ａ］ピロール−１−カルボン酸誘導体
IT1250691B (it) *	1991-07-22	1995-04-21	Giancarlo Santus	Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.
DK0612521T3 (da) *	1991-11-11	2000-01-17	Hisamitsu Pharmaceutical Co	Keterolacholdigt varmt omslag
DE4300697C1 (de) *	1993-01-13	1994-05-19	Roemmers Sa	Keterolac-Derivat mit wesentlich geringerer gastrointestinaler Reizung und Ulzeration
US5622948A (en) *	1994-12-01	1997-04-22	Syntex (U.S.A.) Inc.	Pyrrole pyridazine and pyridazinone anti-inflammatory agents
JP2008210666A (ja) *	2007-02-27	2008-09-11	Okamura Corp	商品陳列棚における照明装置

1977
- 1977-05-17 JP JP5697777A patent/JPS539788A/ja active Granted
- 1977-07-07 DK DK307577A patent/DK151886C/da active
- 1977-07-07 AR AR268356A patent/AR224997A1/es active
- 1977-07-07 GR GR53907A patent/GR61111B/el unknown
- 1977-07-08 IL IL52493A patent/IL52493A/xx unknown
- 1977-07-08 NL NLAANVRAGE7707651,A patent/NL186318C/xx not_active IP Right Cessation
- 1977-07-08 CH CH850077A patent/CH641458A5/de not_active IP Right Cessation
- 1977-07-08 PT PT66780A patent/PT66780B/pt unknown
- 1977-07-08 IE IE1423/77A patent/IE45253B1/en not_active IP Right Cessation
- 1977-07-11 NZ NZ184610A patent/NZ184610A/xx unknown
- 1977-07-11 YU YU1721/77A patent/YU40816B/xx unknown
- 1977-07-11 FR FR7721356A patent/FR2358406A1/fr active Granted
- 1977-07-11 FI FI772153A patent/FI63406C/fi not_active IP Right Cessation
- 1977-07-11 GB GB28919/77A patent/GB1554075A/en not_active Expired
- 1977-07-12 CS CS774646A patent/CS204954B2/cs unknown
- 1977-07-12 CA CA282,599A patent/CA1102809A/en not_active Expired
- 1977-07-13 IT IT68630/77A patent/IT1117313B/it active Protection Beyond IP Right Term
- 1977-07-13 PL PL1977227290A patent/PL124444B1/pl unknown
- 1977-07-13 ES ES460706A patent/ES460706A1/es not_active Expired
- 1977-07-13 PL PL1977227291A patent/PL124445B1/pl unknown
- 1977-07-13 DE DE19772731678 patent/DE2731678A1/de active Granted
- 1977-07-13 SE SE7708141A patent/SE434643B/xx not_active IP Right Cessation
- 1977-07-13 NO NO772494A patent/NO147564C/no unknown
- 1977-07-13 SU SU772501050A patent/SU695558A3/ru active
- 1977-07-13 DE DE2760330A patent/DE2760330C2/de not_active Expired
- 1977-07-13 PL PL1977227289A patent/PL124711B1/pl unknown
- 1977-07-13 PL PL1977199603A patent/PL109390B1/pl unknown
- 1977-07-14 HU HU77SI1582A patent/HU174224B/hu unknown
- 1977-12-20 FR FR7738508A patent/FR2375234A1/fr active Granted
1978
- 1978-05-24 ES ES470214A patent/ES470214A1/es not_active Expired
1979
- 1979-11-22 IL IL58779A patent/IL58779A0/xx unknown
1981
- 1981-04-23 HK HK159/81A patent/HK15981A/xx unknown
- 1981-12-30 MY MY357/81A patent/MY8100357A/xx unknown
1984
- 1984-02-22 CH CH86684A patent/CH646973A5/de not_active IP Right Cessation
- 1984-02-22 CH CH86584A patent/CH646972A5/de not_active IP Right Cessation
1991
- 1991-07-05 MX MX9100104A patent/MX163202B/es unknown
1993
- 1993-03-23 NL NL930021C patent/NL930021I2/nl unknown

Also Published As

Publication number	Publication date
NO772494L (no)	1978-01-17
AU513384B2 (en)	1980-11-27
IL52493A (en)	1982-02-28
DE2731678C2 (it)	1989-06-08
DK151886C (da)	1988-06-06
NZ184610A (en)	1979-03-28
NL186318C (nl)	1990-11-01
MY8100357A (en)	1981-12-31
GR61111B (en)	1978-09-12
ES470214A1 (es)	1979-09-16
FI63406B (fi)	1983-02-28
NL7707651A (nl)	1978-01-17
PL124444B1 (en)	1983-01-31
MX163202B (es)	1992-02-20
AR224997A1 (es)	1982-02-15
JPS539788A (en)	1978-01-28
IE45253B1 (en)	1982-07-14
DE2760330C2 (it)	1989-06-15
IL52493A0 (en)	1977-10-31
JPS6254109B2 (it)	1987-11-13
GB1554075A (en)	1979-10-17
CH641458A5 (en)	1984-02-29
NO147564C (no)	1983-05-18
NO147564B (no)	1983-01-24
SU695558A3 (ru)	1979-10-30
HU174224B (hu)	1979-11-28
PL124711B1 (en)	1983-02-28
YU172177A (en)	1983-09-30
DK151886B (da)	1988-01-11
CH646973A5 (en)	1984-12-28
CA1102809A (en)	1981-06-09
AU2697577A (en)	1979-01-18
FI63406C (fi)	1983-06-10
FR2358406B1 (it)	1981-04-17
YU40816B (en)	1986-06-30
SE434643B (sv)	1984-08-06
CH646972A5 (en)	1984-12-28
FR2358406A1 (fr)	1978-02-10
FI772153A (it)	1978-01-15
CS204954B2 (en)	1981-04-30
PT66780A (fr)	1977-08-01
HK15981A (en)	1981-05-01
PL124445B1 (en)	1983-01-31
DE2731678A1 (de)	1978-03-16
FR2375234B1 (it)	1980-11-07
DK307577A (da)	1978-01-15
NL930021I2 (nl)	1997-03-03
NL186318B (nl)	1990-06-01
ES460706A1 (es)	1978-12-01
IL58779A0 (en)	1980-02-29
NL930021I1 (nl)	1993-05-03
FR2375234A1 (fr)	1978-07-21
IT1117313B (it)	1986-02-17
SE7708141L (sv)	1978-01-15
PL199603A1 (pl)	1978-04-24
PL109390B1 (en)	1980-05-31
IE45253L (en)	1978-01-14

Publication	Publication Date	Title
RO80265A (ro)	1983-04-29	Procedeu pentru prepararea unor derivati de acid beta-carbolin-3-carboxilic
RO75256A (ro)	1980-11-30	Procedeu pentru prepararea unor derivato ai acidului 1,2,3, tiadiazol-5-carboxilic
RO75478A (ro)	1984-04-12	Procedeu pentru prepararea unor derivati ai acidului alfa-fenoxipropionic
RO70687A (ro)	1982-05-10	Procedeu pentru prepararea unor derivati ai acidului fenoxifenoxipropionic
RO70264A (ro)	1983-04-29	Procedeu pentru prepararea unor derivati ai acidului 1-alchil-5-aroilpirol-2-acetic
RO78013A (ro)	1981-12-25	Procedeu pentru prepararea unor derivati de acid tiazolidincarboxilictiazoncarboxilic sau morfolincarboxilic
PT66780B (fr)	1978-12-18	Procede pour la preparation de derives de l'acide 5-aroil-1,2- dihydro-3h-pirrole /1,2-alpha/ pirrole-1-carboxilique
BE890223A (fr)	1982-01-04	Procede de preparation de derives de l'acide quinoleine-carboxylique
PT67004B (fr)	1979-02-12	Procede pour la preparation de derives de l'acide 7-acilamine-8-oxo-3-oxa-1-azabicicle-/4,2,0/-octane-2-carboxique
PT67088A (fr)	1977-10-01	Procede de preparation de derives de l'acide(phenyl-3-amino-2-propionyloxy)-2-acetique
RO79837A (ro)	1983-02-01	Procedeu pentru prepararea acidului cianhidric
RO69712A (fr)	1980-07-15	Procede pour la preparation des thio-ethers d'acide clavulanique
RO77179A (ro)	1981-06-22	Procedeu pentru prepararea unor carboxamide ale 1,1-dioxidului de acid 3,4-dihidre-2-metil-4-oxo-2h-1,2-benzotiazin/3-carboxilic
RO69916A (ro)	1981-04-30	Procedeu pentru prepararea nitrilu.ui acidului 3,7-dimetiloct-2-en-1-oic
BE880031A (fr)	1980-05-14	Procede pour la preparation de 1 alpha, 3 beta-dihydroxy-delta 5-steroides
RO81937A (ro)	1983-06-01	Procedeu pentru prepararea unor derivati ai acidului 7 beta-aminotiazolilacetamido-3-cefem-4-carboxilic
BE861693A (fr)	1978-06-09	Procede de reduction de l'acide 2,5-dicetogluconique
PT74813B (fr)	1983-10-26	Procede de preparation de derives de l'acide 1,4-thiazane-carboxylique
FR2353558A1 (fr)	1977-12-30	Procede pour la preparation de derives de l'acide 7-amino-d3-desacetoxycephalosporanique
BE873495A (fr)	1979-07-16	Procede pour la preparation de la 2,4-difluoro-6-amino-s-triazine
FR2348700A1 (fr)	1977-11-18	Procede pour la preparation de derives para-substitues de l'acide alpha-phenyl-propionique,ainsi que ces derives
BE820267A (fr)	1975-01-16	Procede pour la preparation d'acide p. isobutyle-hydratropique
LU81552A1 (fr)	1979-10-31	Procede pour la preparation de derives de l'acide benzoxazolyl-propionique
FR2351983A1 (fr)	1977-12-16	Procede de preparation de derives de l'acide cephalosporanique
RO73287A (ro)	1981-11-04	Procedeu pentru prepararea unor esteri ai acidului n,n-dimetil-o-pirazolilcarbaminic