PT3159329T - Utilização de derivados de ácidos gordos polinsaturados como medicamentos - Google Patents
Utilização de derivados de ácidos gordos polinsaturados como medicamentosInfo
- Publication number
- PT3159329T PT3159329T PT162011324T PT16201132T PT3159329T PT 3159329 T PT3159329 T PT 3159329T PT 162011324 T PT162011324 T PT 162011324T PT 16201132 T PT16201132 T PT 16201132T PT 3159329 T PT3159329 T PT 3159329T
- Authority
- PT
- Portugal
- Prior art keywords
- hidroxyderivates
- medicaments
- fatty acids
- polyunsaturated fatty
- polyunsaturated
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200900725A ES2345241B1 (es) | 2009-03-16 | 2009-03-16 | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
Publications (1)
Publication Number | Publication Date |
---|---|
PT3159329T true PT3159329T (pt) | 2020-11-13 |
Family
ID=42673244
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT162011324T PT3159329T (pt) | 2009-03-16 | 2010-03-15 | Utilização de derivados de ácidos gordos polinsaturados como medicamentos |
PT107531584T PT2409963T (pt) | 2009-03-16 | 2010-03-15 | Utilização de derivados de ácidos gordos polinsaturados como medicamentos |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT107531584T PT2409963T (pt) | 2009-03-16 | 2010-03-15 | Utilização de derivados de ácidos gordos polinsaturados como medicamentos |
Country Status (19)
Country | Link |
---|---|
US (7) | US9161928B2 (pt) |
EP (2) | EP2409963B1 (pt) |
JP (1) | JP5904592B2 (pt) |
KR (4) | KR20190018754A (pt) |
CN (4) | CN102356057A (pt) |
AU (6) | AU2010224749B2 (pt) |
BR (1) | BRPI1009860A8 (pt) |
CA (1) | CA2754963C (pt) |
CL (1) | CL2011002268A1 (pt) |
DK (2) | DK2409963T3 (pt) |
ES (3) | ES2345241B1 (pt) |
HK (1) | HK1232207A1 (pt) |
HU (2) | HUE051850T2 (pt) |
MX (1) | MX2011009614A (pt) |
PL (1) | PL2409963T3 (pt) |
PT (2) | PT3159329T (pt) |
RU (1) | RU2513995C2 (pt) |
SI (1) | SI3159329T1 (pt) |
WO (1) | WO2010106211A1 (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2345241B1 (es) | 2009-03-16 | 2011-09-08 | Lipopharma Therapeutics | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
US10052299B2 (en) | 2009-10-30 | 2018-08-21 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
EP2701698B1 (en) | 2011-04-26 | 2020-12-23 | Retrotope, Inc. | Disorders implicating pufa oxidation |
AU2012249918B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Impaired energy processing disorders and mitochondrial deficiency |
DK2701697T3 (da) | 2011-04-26 | 2020-06-29 | Retrotope Inc | Oxidative nethindesygdomme |
KR102111997B1 (ko) | 2011-04-26 | 2020-05-18 | 레트로토프 인코포레이티드 | Pufa와 관련된 신경퇴행성 질환 및 근육 질환 |
ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
RU2679443C2 (ru) | 2014-10-21 | 2019-02-11 | Университат Де Лес Ильес Балеарс | Способ синтеза гидрокситриглицеридов и их применение для профилактики и лечения заболеваний |
JP6569919B2 (ja) * | 2015-03-06 | 2019-09-04 | 国立大学法人 新潟大学 | レビー小体型認知症のバイオマーカー |
WO2017091279A1 (en) | 2015-11-23 | 2017-06-01 | Retrotope, Inc. | Site-specific isotopic labeling of 1, 4-diene systems |
GB201521085D0 (en) * | 2015-11-30 | 2016-01-13 | Biozep As | Use |
EP4234035A3 (en) | 2017-05-16 | 2023-11-15 | Ability Pharmaceuticals S.A. | A pharmaceutical combination for the treatment of a cancer |
US10596165B2 (en) | 2018-02-12 | 2020-03-24 | resTORbio, Inc. | Combination therapies |
SG11202012447YA (en) | 2018-06-15 | 2021-01-28 | Navitor Pharm Inc | Rapamycin analogs and uses thereof |
TW202134234A (zh) | 2019-12-05 | 2021-09-16 | 美商奈維特製藥公司 | 雷帕黴素類似物及其用途 |
ES2846824B2 (es) * | 2020-01-29 | 2022-01-19 | Univ Illes Balears | Profarmacos de acidos grasos poliinsaturados y usos medicos de los mismos |
JP2023518640A (ja) * | 2020-01-29 | 2023-05-08 | ウニバシタット デ レス イレス バレアース | αヒドロキシル化脂肪酸代謝産物、その医学的使用およびバイオマーカーとしての使用 |
MX2022008623A (es) | 2020-02-10 | 2022-08-08 | Ability Pharmaceuticals S L | Una combinacion farmaceutica para el tratamiento de un cancer. |
WO2021168311A1 (en) | 2020-02-21 | 2021-08-26 | Retrotope, Inc. | Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof |
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GB8717816D0 (en) | 1987-07-28 | 1987-09-03 | Manchester Inst Science Tech | Fabric testing apparatus |
GB2218984B (en) * | 1988-05-27 | 1992-09-23 | Renafield Limited | Process for preparing high-concentration mixtures of polyunsaturated fatty acids & their esters and their prophylactic or therapeutic uses |
JPH05974A (ja) * | 1991-06-21 | 1993-01-08 | Sagami Chem Res Center | ハロゲン化不飽和アルキル化合物及びその前駆体 |
ES2161146B1 (es) * | 1999-06-29 | 2002-07-01 | Consejo Superior Investigacion | Compuestos antimicrobianos, uso y metodo para inducir resistencia a infecciones de bacterias en plantas. |
US6344574B1 (en) | 2000-07-20 | 2002-02-05 | The United States Of America As Represented By The Secretary Of Agriculture | Solvent fractionation of chicken fat for making lipid compositions enriched in unsaturated fatty acid-containing triacylglycerols |
DE10106660A1 (de) * | 2001-02-12 | 2002-08-29 | Celanese Ventures Gmbh | Verfahren zur Herstellung von gamma-Linolensäure aus einer Ciliaten-Kultur durch Zusatz geeigneter Vorläufermoleküle zu dem Kulturmedium |
ES2186576B1 (es) * | 2001-10-11 | 2004-09-16 | Universitat De Les Illes Balears | Acido 2-hidroxioleico para utilizar como medicamento. |
WO2003084305A2 (en) * | 2002-04-01 | 2003-10-16 | University Of Southern California | Trihydroxy polyunsaturated eicosanoids |
US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
KR20070090928A (ko) * | 2004-11-19 | 2007-09-06 | 마텍 바이오싸이언스스 코포레이션 | 장쇄 다가불포화 지방산으로부터의 옥시리핀, 및 이의 제조방법 및 사용 방법 |
GB0428384D0 (en) | 2004-12-24 | 2005-02-02 | Sla Pharma Ag | Eicosapentaenoic acid |
US8324276B2 (en) * | 2005-01-24 | 2012-12-04 | Pronova Biopharma Norge As | Fatty acid composition for treatment of alzheimer's disease and cognitive dysfunction |
CN101213281B (zh) * | 2005-05-04 | 2013-03-13 | 普罗诺瓦生物医药挪威公司 | 新的dha衍生物及其作为药物的用途 |
AU2006242914B2 (en) * | 2005-05-04 | 2012-02-02 | Pronova Biopharma Norge As | New DHA derivatives and their use as medicaments |
US8059805B2 (en) * | 2005-06-30 | 2011-11-15 | Emc Corporation | Enhanced services provided using communication redirection and processing |
CN103211807A (zh) | 2005-07-08 | 2013-07-24 | Dsmip资产公司 | 用于治疗痴呆和前痴呆相关病症的多不饱和脂肪酸 |
EP1772146A1 (en) * | 2005-10-03 | 2007-04-11 | Neuropharma, S.A. | Polyunsaturated fatty acids as bace inhibitors |
WO2007058523A1 (en) * | 2005-11-17 | 2007-05-24 | N.V. Nutricia | Composition with docosapentaenoic acid |
DK1800675T3 (da) * | 2005-12-23 | 2011-09-05 | Nutricia Nv | Sammensætninger omfattende polyumættede fedtsyrer, proteiner og mangan og/eller molybdæn og nucleosider/nucleotider til behandling af demens |
JP2010508262A (ja) | 2006-11-01 | 2010-03-18 | プロノヴァ バイオファーマ ノルゲ アーエス | 組成物 |
CN101535238A (zh) * | 2006-11-01 | 2009-09-16 | 普罗诺瓦生物医药挪威公司 | 作为过氧化物酶体增生物激活受体(PPAR)的活化剂或调节剂的α-取代的ω-3脂质 |
WO2008053340A1 (en) * | 2006-11-03 | 2008-05-08 | Pronova Biopharma Norge As | A combination product comprising at least one lipid substituted in the alpha position and at least one hypoglycemic agent |
US20080234377A1 (en) * | 2007-03-23 | 2008-09-25 | Martek Biosciences Corporation | Polyunsaturated fatty acids for treatment of dementia and pre-dementia-related conditions |
ES2345241B1 (es) * | 2009-03-16 | 2011-09-08 | Lipopharma Therapeutics | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
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2009
- 2009-03-16 ES ES200900725A patent/ES2345241B1/es active Active
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2010
- 2010-03-15 ES ES10753158.4T patent/ES2613606T3/es active Active
- 2010-03-15 KR KR1020197004239A patent/KR20190018754A/ko active Search and Examination
- 2010-03-15 DK DK10753158.4T patent/DK2409963T3/en active
- 2010-03-15 PT PT162011324T patent/PT3159329T/pt unknown
- 2010-03-15 CA CA2754963A patent/CA2754963C/en active Active
- 2010-03-15 HU HUE16201132A patent/HUE051850T2/hu unknown
- 2010-03-15 KR KR1020207005917A patent/KR102233102B1/ko active IP Right Grant
- 2010-03-15 CN CN2010800119398A patent/CN102356057A/zh active Pending
- 2010-03-15 US US13/257,128 patent/US9161928B2/en active Active
- 2010-03-15 EP EP10753158.4A patent/EP2409963B1/en active Active
- 2010-03-15 PL PL10753158T patent/PL2409963T3/pl unknown
- 2010-03-15 RU RU2011141850/04A patent/RU2513995C2/ru active
- 2010-03-15 JP JP2012500281A patent/JP5904592B2/ja active Active
- 2010-03-15 CN CN201610773030.5A patent/CN106420686B/zh active Active
- 2010-03-15 BR BRPI1009860A patent/BRPI1009860A8/pt not_active Application Discontinuation
- 2010-03-15 HU HUE10753158A patent/HUE032027T2/en unknown
- 2010-03-15 ES ES16201132T patent/ES2820025T3/es active Active
- 2010-03-15 KR KR1020117024210A patent/KR101833772B1/ko active IP Right Grant
- 2010-03-15 EP EP16201132.4A patent/EP3159329B1/en active Active
- 2010-03-15 KR KR1020187005245A patent/KR20180021931A/ko not_active Application Discontinuation
- 2010-03-15 SI SI201032041T patent/SI3159329T1/sl unknown
- 2010-03-15 PT PT107531584T patent/PT2409963T/pt unknown
- 2010-03-15 WO PCT/ES2010/070153 patent/WO2010106211A1/es active Application Filing
- 2010-03-15 DK DK16201132.4T patent/DK3159329T3/da active
- 2010-03-15 MX MX2011009614A patent/MX2011009614A/es active IP Right Grant
- 2010-03-15 CN CN201910095352.2A patent/CN109999018A/zh active Pending
- 2010-03-15 AU AU2010224749A patent/AU2010224749B2/en not_active Revoked
- 2010-03-15 CN CN201610773061.0A patent/CN106349058B/zh active Active
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2011
- 2011-09-13 CL CL2011002268A patent/CL2011002268A1/es unknown
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2015
- 2015-09-29 US US14/869,045 patent/US9763906B2/en active Active
- 2015-09-29 US US14/869,080 patent/US9763907B2/en active Active
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2016
- 2016-07-13 US US15/209,540 patent/US9907772B2/en active Active
- 2016-10-07 AU AU2016238970A patent/AU2016238970B2/en not_active Revoked
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2017
- 2017-06-02 HK HK17105487.0A patent/HK1232207A1/zh unknown
- 2017-08-22 US US15/683,379 patent/US10201515B2/en active Active
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2018
- 2018-06-05 AU AU2018203976A patent/AU2018203976B2/en not_active Expired - Fee Related
- 2018-12-18 US US16/224,262 patent/US20190365690A1/en not_active Abandoned
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2019
- 2019-09-06 AU AU2019226257A patent/AU2019226257B2/en active Active
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2020
- 2020-04-22 US US16/855,463 patent/US11253497B2/en active Active
- 2020-07-13 AU AU2020205213A patent/AU2020205213B2/en active Active
- 2020-07-13 AU AU2020205214A patent/AU2020205214B2/en active Active
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