PT3116475T - Composições de inibidores de dopa-descarboxilase - Google Patents

Composições de inibidores de dopa-descarboxilase

Info

Publication number
PT3116475T
PT3116475T PT157317272T PT15731727T PT3116475T PT 3116475 T PT3116475 T PT 3116475T PT 157317272 T PT157317272 T PT 157317272T PT 15731727 T PT15731727 T PT 15731727T PT 3116475 T PT3116475 T PT 3116475T
Authority
PT
Portugal
Prior art keywords
decarboxylase inhibitor
inhibitor compositions
dopa decarboxylase
dopa
compositions
Prior art date
Application number
PT157317272T
Other languages
English (en)
Original Assignee
Neuroderm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroderm Ltd filed Critical Neuroderm Ltd
Publication of PT3116475T publication Critical patent/PT3116475T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/133Amines having hydroxy groups, e.g. sphingosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT157317272T 2014-03-13 2015-03-12 Composições de inibidores de dopa-descarboxilase PT3116475T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461952477P 2014-03-13 2014-03-13
US201461990967P 2014-05-09 2014-05-09

Publications (1)

Publication Number Publication Date
PT3116475T true PT3116475T (pt) 2020-12-15

Family

ID=53488380

Family Applications (2)

Application Number Title Priority Date Filing Date
PT201983715T PT3777833T (pt) 2014-03-13 2015-03-12 Composições do inibidor de dopa-descarboxilase
PT157317272T PT3116475T (pt) 2014-03-13 2015-03-12 Composições de inibidores de dopa-descarboxilase

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT201983715T PT3777833T (pt) 2014-03-13 2015-03-12 Composições do inibidor de dopa-descarboxilase

Country Status (19)

Country Link
US (4) US10022320B2 (pt)
EP (3) EP3777833B1 (pt)
JP (2) JP6591995B2 (pt)
CN (1) CN106413754B (pt)
AU (1) AU2015228369B2 (pt)
BR (1) BR112016021034A8 (pt)
CA (1) CA2942244C (pt)
DK (2) DK3116475T3 (pt)
ES (2) ES2836325T3 (pt)
FI (1) FI3777833T3 (pt)
HR (2) HRP20231716T1 (pt)
HU (2) HUE064818T2 (pt)
IL (1) IL247668B (pt)
MX (1) MX2016011837A (pt)
PL (2) PL3777833T3 (pt)
PT (2) PT3777833T (pt)
RS (1) RS65060B1 (pt)
RU (1) RU2684105C2 (pt)
WO (1) WO2015136538A1 (pt)

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* Cited by examiner, † Cited by third party
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EP3192500B1 (en) 2009-05-19 2020-12-02 Neuroderm Ltd Compositions for continuous administration of dopa decarboxylase inhibitors
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FI3777833T3 (fi) 2014-03-13 2024-01-03 Neuroderm Ltd Dopa-dekarboksylaasin estäjän koostumuksia
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
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WO2020178810A1 (en) * 2019-03-04 2020-09-10 Neuroderm, Ltd. Pharmaceutical compositions comprising levodopa amide derivatives and uses thereof
CN111701024B (zh) * 2020-05-26 2022-05-24 上海京新生物医药有限公司 一种左旋多巴制剂及其制备方法及其应用
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
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CN113396897B (zh) * 2021-07-26 2022-06-07 苏州华测生物技术有限公司 一种稳定生物基质中卡比多巴/左旋多巴的方法

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Also Published As

Publication number Publication date
BR112016021034A2 (pt) 2017-08-15
RU2684105C2 (ru) 2019-04-04
EP4299128A3 (en) 2024-04-17
HUE052642T2 (hu) 2021-05-28
EP3116475B1 (en) 2020-11-04
MX2016011837A (es) 2017-04-27
AU2015228369B2 (en) 2020-05-21
US20210038505A1 (en) 2021-02-11
US10022320B2 (en) 2018-07-17
ES2836325T3 (es) 2021-06-24
PL3116475T3 (pl) 2021-02-08
CN106413754B (zh) 2019-11-29
EP3777833A1 (en) 2021-02-17
US20230240980A1 (en) 2023-08-03
AU2015228369A1 (en) 2016-10-27
RS65060B1 (sr) 2024-02-29
HRP20231716T1 (hr) 2024-03-15
DK3777833T3 (da) 2023-12-18
CN106413754A (zh) 2017-02-15
CA2942244A1 (en) 2015-09-17
US20190151233A1 (en) 2019-05-23
JP6770158B2 (ja) 2020-10-14
PL3777833T3 (pl) 2024-03-25
PT3777833T (pt) 2024-01-09
BR112016021034A8 (pt) 2021-06-29
IL247668A0 (en) 2016-11-30
WO2015136538A1 (en) 2015-09-17
US10624839B2 (en) 2020-04-21
US20150352212A1 (en) 2015-12-10
EP3116475A1 (en) 2017-01-18
EP3777833B1 (en) 2023-10-18
JP2017507973A (ja) 2017-03-23
RU2016135952A (ru) 2018-04-13
JP6591995B2 (ja) 2019-10-16
JP2020011977A (ja) 2020-01-23
RU2016135952A3 (pt) 2018-09-12
EP4299128A2 (en) 2024-01-03
IL247668B (en) 2020-09-30
HUE064818T2 (hu) 2024-04-28
CA2942244C (en) 2022-08-23
HRP20201948T1 (hr) 2021-01-22
DK3116475T3 (da) 2020-12-07
FI3777833T3 (fi) 2024-01-03
ES2967693T3 (es) 2024-05-03

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