PT3057934T - Ésteres halogenados de ácidos gordos insaturados ciclopropanados para uso no tratamento de doenças neurodegenerativas - Google Patents
Ésteres halogenados de ácidos gordos insaturados ciclopropanados para uso no tratamento de doenças neurodegenerativasInfo
- Publication number
- PT3057934T PT3057934T PT14793391T PT14793391T PT3057934T PT 3057934 T PT3057934 T PT 3057934T PT 14793391 T PT14793391 T PT 14793391T PT 14793391 T PT14793391 T PT 14793391T PT 3057934 T PT3057934 T PT 3057934T
- Authority
- PT
- Portugal
- Prior art keywords
- cyclopropanated
- treatment
- fatty acids
- unsaturated fatty
- neurodegenerative diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
- C07C69/635—Halogen-containing esters of saturated acids containing rings in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361892727P | 2013-10-18 | 2013-10-18 | |
US201361896735P | 2013-10-29 | 2013-10-29 | |
US201461925449P | 2014-01-09 | 2014-01-09 | |
US201461925441P | 2014-01-09 | 2014-01-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT3057934T true PT3057934T (pt) | 2019-06-28 |
Family
ID=51846995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT14793391T PT3057934T (pt) | 2013-10-18 | 2014-10-20 | Ésteres halogenados de ácidos gordos insaturados ciclopropanados para uso no tratamento de doenças neurodegenerativas |
Country Status (9)
Country | Link |
---|---|
US (3) | US9962357B2 (pt) |
EP (3) | EP3567025B8 (pt) |
JP (1) | JP2016535012A (pt) |
CA (1) | CA2927675A1 (pt) |
DK (1) | DK3057934T3 (pt) |
ES (2) | ES2927760T3 (pt) |
PL (1) | PL3057934T3 (pt) |
PT (1) | PT3057934T (pt) |
WO (1) | WO2015058191A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20180311209A1 (en) | 2015-10-08 | 2018-11-01 | Cognitive Research Enterprises, Inc. | Dosing regimens of pkc activators |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY118354A (en) * | 1995-05-01 | 2004-10-30 | Scarista Ltd | 1,3-propane diol derivatives as bioactive compounds |
JPH10139735A (ja) * | 1996-09-13 | 1998-05-26 | Sumitomo Chem Co Ltd | エステル化合物、それを有効成分とする有害生物防除剤およびその製造中間体 |
WO2001062740A1 (en) * | 2000-02-25 | 2001-08-30 | South Alabama Medical Science Foundation | Mibefradil analogues and their use |
WO2004050062A2 (en) | 2002-12-03 | 2004-06-17 | Blanchette Rockefeller Neurosciences Institute | Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier |
US7521447B2 (en) * | 2003-03-03 | 2009-04-21 | Array Biopharma Inc. | P38 inhibitors and methods of use thereof |
DE10351087A1 (de) * | 2003-10-31 | 2005-05-25 | Bayer Technology Services Gmbh | Feste Wirkstoff-Formulierung |
CN101223884B (zh) * | 2007-01-15 | 2011-07-13 | 大日本除虫菊株式会社 | 杀虫防虫剂或害虫的摄食阻碍剂 |
US8163800B2 (en) | 2008-07-28 | 2012-04-24 | Blanchette Rockefeller Neurosciences Institute | PKC-activating compounds for the treatment of neurodegenerative diseases |
CN101608402B (zh) * | 2009-07-14 | 2011-07-27 | 东华大学 | 植物油改性含氟拒水整理剂、制备方法及其应用 |
JP5934102B2 (ja) * | 2009-10-30 | 2016-06-15 | レトロトップ、 インコーポレイテッドRetrotope, Inc. | Pufa誘導体による酸化ストレス障害の緩和 |
EP2693876B1 (en) * | 2011-04-08 | 2020-01-15 | Sphaera Pharma Pte. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
US20120294924A1 (en) * | 2011-04-29 | 2012-11-22 | Thomas Tice | Peptide-Lipid Conjugates And Uses Thereof |
EP2780316B1 (en) | 2011-11-13 | 2020-04-15 | Blanchette Rockefeller Neurosciences Institute | Esters of dcpla and methods of treatment using the same |
-
2014
- 2014-10-20 EP EP19164672.8A patent/EP3567025B8/en active Active
- 2014-10-20 US US15/028,487 patent/US9962357B2/en active Active
- 2014-10-20 DK DK14793391.5T patent/DK3057934T3/da active
- 2014-10-20 JP JP2016524133A patent/JP2016535012A/ja active Pending
- 2014-10-20 WO PCT/US2014/061368 patent/WO2015058191A1/en active Application Filing
- 2014-10-20 EP EP22184036.6A patent/EP4101835A1/en active Pending
- 2014-10-20 PL PL14793391T patent/PL3057934T3/pl unknown
- 2014-10-20 PT PT14793391T patent/PT3057934T/pt unknown
- 2014-10-20 ES ES19164672T patent/ES2927760T3/es active Active
- 2014-10-20 CA CA2927675A patent/CA2927675A1/en not_active Abandoned
- 2014-10-20 ES ES14793391T patent/ES2732153T3/es active Active
- 2014-10-20 EP EP14793391.5A patent/EP3057934B1/en active Active
-
2018
- 2018-04-04 US US15/945,041 patent/US20180325856A1/en not_active Abandoned
-
2019
- 2019-01-25 US US16/257,988 patent/US11273139B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP4101835A1 (en) | 2022-12-14 |
US20180325856A1 (en) | 2018-11-15 |
EP3057934B1 (en) | 2019-03-27 |
WO2015058191A1 (en) | 2015-04-23 |
ES2732153T3 (es) | 2019-11-20 |
US20160256427A1 (en) | 2016-09-08 |
PL3057934T3 (pl) | 2019-09-30 |
EP3057934A1 (en) | 2016-08-24 |
ES2927760T3 (es) | 2022-11-10 |
EP3567025B8 (en) | 2023-01-25 |
US9962357B2 (en) | 2018-05-08 |
US20220151973A1 (en) | 2022-05-19 |
DK3057934T3 (da) | 2019-07-01 |
US20190192471A1 (en) | 2019-06-27 |
ES2927760T8 (es) | 2023-05-05 |
EP3567025A1 (en) | 2019-11-13 |
EP3567025B1 (en) | 2022-08-03 |
CA2927675A1 (en) | 2015-04-23 |
US11273139B2 (en) | 2022-03-15 |
JP2016535012A (ja) | 2016-11-10 |
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