PT3004163T - Método para purificação de anticorpo - Google Patents

Método para purificação de anticorpo

Info

Publication number
PT3004163T
PT3004163T PT148084205T PT14808420T PT3004163T PT 3004163 T PT3004163 T PT 3004163T PT 148084205 T PT148084205 T PT 148084205T PT 14808420 T PT14808420 T PT 14808420T PT 3004163 T PT3004163 T PT 3004163T
Authority
PT
Portugal
Prior art keywords
purifying antibody
purifying
antibody
Prior art date
Application number
PT148084205T
Other languages
English (en)
Original Assignee
Prestige Biopharma Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prestige Biopharma Pte Ltd filed Critical Prestige Biopharma Pte Ltd
Publication of PT3004163T publication Critical patent/PT3004163T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
PT148084205T 2013-06-05 2014-06-03 Método para purificação de anticorpo PT3004163T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020130064803A KR101569783B1 (ko) 2013-06-05 2013-06-05 항체의 정제 방법

Publications (1)

Publication Number Publication Date
PT3004163T true PT3004163T (pt) 2020-10-27

Family

ID=52008363

Family Applications (1)

Application Number Title Priority Date Filing Date
PT148084205T PT3004163T (pt) 2013-06-05 2014-06-03 Método para purificação de anticorpo

Country Status (7)

Country Link
US (1) US10053489B2 (pt)
EP (1) EP3004163B1 (pt)
KR (1) KR101569783B1 (pt)
DK (1) DK3004163T3 (pt)
ES (1) ES2826123T3 (pt)
PT (1) PT3004163T (pt)
WO (1) WO2014196780A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
EP2830651A4 (en) 2013-03-12 2015-09-02 Abbvie Inc HUMAN ANTIBODIES THAT BIND TNF-ALPHA AND PREPARATION METHODS
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
KR102369014B1 (ko) 2016-08-16 2022-03-02 리제너론 파아마슈티컬스, 인크. 혼합물로부터 개별 항체들을 정량하는 방법
KR20230119729A (ko) 2016-10-25 2023-08-16 리제너론 파아마슈티컬스, 인크. 크로마토그래피 데이터 분석을 위한 방법 및 시스템
WO2018190677A2 (en) * 2017-04-14 2018-10-18 Cj Healthcare Corporation Method for purifying analogous antibody using cation-exchange chromatography
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
CN108805099B (zh) * 2018-06-22 2021-06-11 南京工程学院 一种基于emd的零相位滤波器设计方法
TW202005694A (zh) 2018-07-02 2020-02-01 美商里珍納龍藥品有限公司 自混合物製備多肽之系統及方法
CN111471084A (zh) * 2019-01-23 2020-07-31 中国科学院青岛生物能源与过程研究所 一种用于蛋白沉淀的装置及从蛋白混合液中分离纯化目的蛋白的方法
EP4061825A1 (en) 2019-11-22 2022-09-28 MorphoSys AG Method to increase antibody yield during ion exchange chromatography
KR102153258B1 (ko) * 2020-02-21 2020-09-07 프레스티지바이오로직스 주식회사 베바시주맙 정제의 최적화된 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060257972A1 (en) * 2003-03-31 2006-11-16 Takashi Ishihara Purification of human monoclonal antibody and human polyclonal antibody
JP2008535913A (ja) 2005-04-11 2008-09-04 メダレックス インコーポレーティッド タンパク質精製方法
US20100190210A1 (en) 2006-03-20 2010-07-29 Medarex, Inc. Protein Purification
EP2235056A1 (en) 2007-12-21 2010-10-06 Genentech, Inc. Crystallization of anti-cd20 antibodies
CN105111309A (zh) * 2008-10-20 2015-12-02 Abbvie公司 使用a蛋白亲和层析分离和纯化抗体
BRPI0920572A8 (pt) * 2008-10-20 2015-10-27 Abbott Lab Inativação viral durante a purificação dos anticorpos
US20120282654A1 (en) 2009-04-29 2012-11-08 Schering Corporation Antibody purification
WO2013158279A1 (en) * 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species

Also Published As

Publication number Publication date
US20160122384A1 (en) 2016-05-05
KR101569783B1 (ko) 2015-11-19
EP3004163A4 (en) 2017-01-25
US10053489B2 (en) 2018-08-21
EP3004163A1 (en) 2016-04-13
WO2014196780A1 (en) 2014-12-11
EP3004163B1 (en) 2020-07-29
ES2826123T3 (es) 2021-05-17
DK3004163T3 (en) 2020-11-02
KR20140142974A (ko) 2014-12-15

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