PT2746265E - Derivado heterocíclico como inibidor de pronstaglandina-sintase microssomal (mpge) - Google Patents
Derivado heterocíclico como inibidor de pronstaglandina-sintase microssomal (mpge) Download PDFInfo
- Publication number
- PT2746265E PT2746265E PT128235108T PT12823510T PT2746265E PT 2746265 E PT2746265 E PT 2746265E PT 128235108 T PT128235108 T PT 128235108T PT 12823510 T PT12823510 T PT 12823510T PT 2746265 E PT2746265 E PT 2746265E
- Authority
- PT
- Portugal
- Prior art keywords
- mpges
- synthase
- inhibitor
- heterocyclic derivative
- microsomal prostaglandin
- Prior art date
Links
- 102000004226 Prostaglandin-E Synthases Human genes 0.000 title 1
- 108090000748 Prostaglandin-E Synthases Proteins 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000003228 microsomal effect Effects 0.000 title 1
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- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
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- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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