PT2438446E - Métodos, reagentes e kits para realizar imunofenotipagem por citometria de fluxo - Google Patents
Métodos, reagentes e kits para realizar imunofenotipagem por citometria de fluxo Download PDFInfo
- Publication number
- PT2438446E PT2438446E PT107279853T PT10727985T PT2438446E PT 2438446 E PT2438446 E PT 2438446E PT 107279853 T PT107279853 T PT 107279853T PT 10727985 T PT10727985 T PT 10727985T PT 2438446 E PT2438446 E PT 2438446E
- Authority
- PT
- Portugal
- Prior art keywords
- kits
- reagents
- methods
- flow cytometric
- cytometric immunophenotyping
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 238000013394 immunophenotyping Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4915—Blood using flow cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1413—Hydrodynamic focussing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Ecology (AREA)
- Dispersion Chemistry (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09161870A EP2259065A1 (en) | 2009-06-03 | 2009-06-03 | Methods, reagents and kits for flow cytometric immunophenotyping |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2438446E true PT2438446E (pt) | 2014-06-12 |
Family
ID=41259006
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT17165543T PT3206031T (pt) | 2009-06-03 | 2010-06-02 | Métodos, reagentes e estojos para imunofenotipagem citométrica de fluxo |
PT107279853T PT2438446E (pt) | 2009-06-03 | 2010-06-02 | Métodos, reagentes e kits para realizar imunofenotipagem por citometria de fluxo |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT17165543T PT3206031T (pt) | 2009-06-03 | 2010-06-02 | Métodos, reagentes e estojos para imunofenotipagem citométrica de fluxo |
Country Status (12)
Country | Link |
---|---|
US (5) | US9880158B2 (pt) |
EP (4) | EP2259065A1 (pt) |
JP (4) | JP5795308B2 (pt) |
AU (5) | AU2010254680B2 (pt) |
CA (2) | CA3044453C (pt) |
DK (3) | DK2438446T3 (pt) |
ES (3) | ES2724633T3 (pt) |
HU (1) | HUE044269T2 (pt) |
PL (3) | PL3206031T3 (pt) |
PT (2) | PT3206031T (pt) |
TR (1) | TR201906754T4 (pt) |
WO (1) | WO2010140885A1 (pt) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
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EP2259065A1 (en) * | 2009-06-03 | 2010-12-08 | Erasmus University Medical Center Rotterdam | Methods, reagents and kits for flow cytometric immunophenotyping |
JP5791095B2 (ja) * | 2010-12-10 | 2015-10-07 | 国立大学法人金沢大学 | Pnh型白血球の検出方法 |
EP2495567A1 (en) * | 2011-03-04 | 2012-09-05 | Erasmus University Medical Center Rotterdam | Methods and means for monitoring disruption of tissue homeostasis in the total body |
US9777332B2 (en) | 2011-03-31 | 2017-10-03 | St. Jude Children's Research Hospital | Methods and compositions for identifying minimal residual disease in acute lymphoblastic leukemia |
ES2660429T3 (es) * | 2012-06-14 | 2018-03-22 | Erasmus University Medical Center Rotterdam | Métodos, reactivos y kits para detectar enfermedad residual mínima |
CN103018463B (zh) * | 2012-12-20 | 2015-08-05 | 北京大学人民医院 | 检测急性b淋巴细胞白血病相关免疫表型的试剂盒及其应用 |
CN107209101B (zh) | 2014-10-30 | 2019-10-25 | 鹿特丹伊拉斯谟大学医疗中心 | 用于诊断原发性免疫缺陷的试剂、方法和试剂盒 |
CN105223361B (zh) * | 2015-08-28 | 2017-05-17 | 北京大学人民医院 | 一种检测急性t淋巴细胞白血病幼稚t细胞的试剂盒、应用及方法 |
WO2017094008A1 (en) | 2015-12-01 | 2017-06-08 | The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center | Improved cytometric assays |
CN105606797B (zh) * | 2016-01-15 | 2016-09-07 | 浙江博真生物科技有限公司 | 抗体组合物及其在白血病淋巴瘤分型中的应用 |
FR3051555B1 (fr) * | 2016-05-20 | 2018-05-11 | Horiba Abx Sas | Detection de la maladie residuelle du myelome multiple |
GB201617572D0 (en) | 2016-10-17 | 2016-11-30 | Ospedale San Raffaele | Use, method, kit, composition and antibodies |
ES2867860T3 (es) | 2016-12-23 | 2021-10-21 | Cytognos S L | Método de clasificación de información digital |
JP7084695B2 (ja) * | 2017-03-28 | 2022-06-15 | シスメックス株式会社 | 試薬選択支援装置、方法、プログラムおよび記録媒体並びに試料測定装置 |
CA3071287A1 (en) | 2017-08-31 | 2019-03-07 | Agilent Technologies, Inc. | Composition for stabilization of antibody formulations containing percp |
CN110716051B (zh) * | 2018-07-13 | 2022-11-29 | 迈健医药科技无锡有限公司 | 一种免疫细胞全维分析方法 |
US10854040B1 (en) | 2019-07-18 | 2020-12-01 | Adp Gauselmann Gmbh | Gaming system and method providing expanding symbols |
NL2024163B1 (en) * | 2019-11-05 | 2021-07-20 | Univ Of Salamanca | Means and methods for multiparameter cytometry-based leukocyte subsetting. |
WO2021129976A1 (en) | 2019-12-27 | 2021-07-01 | Scailyte Ag | Method for diagnosing cutaneous t-cell lymphoma diseases |
WO2021231071A1 (en) * | 2020-05-13 | 2021-11-18 | Becton, Dickinson And Company | Blood based controls for complex panel |
AU2021287606A1 (en) | 2020-06-10 | 2022-12-15 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Means and methods for the diagnosis, classification and/or monitoring of pediatric tumors. |
CN112578117B (zh) * | 2021-02-22 | 2021-05-25 | 信纳克(北京)生化标志物检测医学研究有限责任公司 | 抗体组合物及其筛查移植后淋巴细胞增殖性疾病的应用 |
CN112552407B (zh) * | 2021-02-24 | 2021-05-25 | 信纳克(北京)生化标志物检测医学研究有限责任公司 | 抗体组合物及其在检测急性b淋巴细胞白血病中的应用 |
CN113188982B (zh) * | 2021-04-30 | 2022-05-10 | 天津深析智能科技发展有限公司 | 淋巴细胞亚群自动分析中有效去除单核细胞干扰的方法 |
CN113777327B (zh) * | 2021-09-13 | 2022-09-02 | 北京大学人民医院 | 用于白血病/淋巴瘤免疫分型初筛的抗体组合物及其应用 |
WO2023081320A1 (en) * | 2021-11-04 | 2023-05-11 | Orca Biosystems, Inc. | Therapeutic compositions and methods for allogeneic hematopoietic stem cell transplantation |
CN113933513B (zh) * | 2021-12-15 | 2022-03-04 | 信纳克(北京)生化标志物检测医学研究有限责任公司 | 检测靶向治疗后急性t淋巴细胞白血病的试剂组合物及其应用 |
CN114264825B (zh) * | 2021-12-22 | 2023-08-15 | 重庆医科大学附属儿童医院 | 一种b淋巴细胞发育亚群免疫分型的方法和试剂盒 |
CN114460311B (zh) * | 2022-04-13 | 2022-07-05 | 北京大学人民医院 | 用于b-all/lbl免疫分型的试剂组合物及其应用 |
CN116593699B (zh) * | 2023-07-13 | 2023-10-03 | 天津市肿瘤医院空港医院 | 应用于流式细胞术检测t细胞表面cd39分子的检测方法 |
CN118130798B (zh) * | 2024-05-06 | 2024-07-30 | 北京大学人民医院 | 一种用于流式细胞检测急性t淋巴细胞白血病/淋巴瘤免疫表型的抗体组合及其应用 |
CN118130779B (zh) * | 2024-05-06 | 2024-07-23 | 成都尚元太生物科技有限公司 | 检测活化炎性细胞的组合物、其用途以及检测活化炎性细胞的检测试剂盒及方法 |
Family Cites Families (13)
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US5047321A (en) | 1988-06-15 | 1991-09-10 | Becton Dickinson & Co. | Method for analysis of cellular components of a fluid |
US5234816A (en) * | 1991-07-12 | 1993-08-10 | Becton, Dickinson And Company | Method for the classification and monitoring of leukemias |
CA2087086A1 (en) | 1992-01-22 | 1993-07-23 | Leon Wmm Terstappen | Multidimensional cell differential analysis |
ES2051651B1 (es) | 1992-12-10 | 1995-01-01 | Univ Salamanca | Procedimiento para la cuantificacion simultanea, en una sola medicion, de los principales tipos de linfocitos humanos y sus subpoblaciones. |
US6761883B2 (en) * | 1999-06-29 | 2004-07-13 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian myeloid progenitor cell subsets |
DK1363126T3 (da) | 2002-05-14 | 2006-04-18 | Univ Salamanca | Flerdimensionel differentiel analyse af leukocyter |
US7507548B2 (en) | 2003-03-04 | 2009-03-24 | University Of Salamanca | Multidimensional detection of aberrant phenotypes in neoplastic cells to be used to monitor minimal disease levels using flow cytometry measurements |
EP1627563A1 (en) * | 2004-08-10 | 2006-02-22 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Means and methods for producing a stabilized cell of interest |
JP2007105037A (ja) * | 2005-09-16 | 2007-04-26 | Univ Of Tokyo | キメリズムを利用した幹細胞移植のための検査 |
US7321843B2 (en) | 2005-09-30 | 2008-01-22 | Universidad De Salamanca | Method for generating new flow cytometry data files containing an infinite number of dimensions based on data estimation |
JP2007263958A (ja) * | 2006-02-28 | 2007-10-11 | Nippon Medical Soken:Kk | 血液細胞の分類法および診断ならびにそれを利用したテイラーメード治療および予防 |
WO2008122051A1 (en) * | 2007-04-02 | 2008-10-09 | Acoustic Cytometry Systems, Inc. | Methods and devices for enhanced analysis of field focused cells and particles |
EP2259065A1 (en) | 2009-06-03 | 2010-12-08 | Erasmus University Medical Center Rotterdam | Methods, reagents and kits for flow cytometric immunophenotyping |
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2009
- 2009-06-03 EP EP09161870A patent/EP2259065A1/en not_active Withdrawn
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2010
- 2010-06-02 PL PL17165543T patent/PL3206031T3/pl unknown
- 2010-06-02 US US13/376,103 patent/US9880158B2/en active Active
- 2010-06-02 EP EP17165543.4A patent/EP3206031B1/en active Active
- 2010-06-02 JP JP2012513893A patent/JP5795308B2/ja active Active
- 2010-06-02 DK DK10727985.3T patent/DK2438446T3/da active
- 2010-06-02 DK DK17165543.4T patent/DK3206031T3/da active
- 2010-06-02 EP EP10727985.3A patent/EP2438446B1/en active Active
- 2010-06-02 ES ES17165543T patent/ES2724633T3/es active Active
- 2010-06-02 CA CA3044453A patent/CA3044453C/en active Active
- 2010-06-02 WO PCT/NL2010/050332 patent/WO2010140885A1/en active Application Filing
- 2010-06-02 PL PL14158924T patent/PL2743698T3/pl unknown
- 2010-06-02 AU AU2010254680A patent/AU2010254680B2/en active Active
- 2010-06-02 EP EP14158924.2A patent/EP2743698B1/en active Active
- 2010-06-02 PT PT17165543T patent/PT3206031T/pt unknown
- 2010-06-02 ES ES10727985.3T patent/ES2464736T3/es active Active
- 2010-06-02 HU HUE17165543 patent/HUE044269T2/hu unknown
- 2010-06-02 DK DK14158924.2T patent/DK2743698T3/en active
- 2010-06-02 ES ES14158924.2T patent/ES2627952T3/es active Active
- 2010-06-02 CA CA2764670A patent/CA2764670C/en active Active
- 2010-06-02 PL PL10727985T patent/PL2438446T3/pl unknown
- 2010-06-02 PT PT107279853T patent/PT2438446E/pt unknown
- 2010-06-02 TR TR2019/06754T patent/TR201906754T4/tr unknown
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2015
- 2015-08-11 JP JP2015158867A patent/JP6207556B2/ja active Active
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2016
- 2016-01-27 AU AU2016200462A patent/AU2016200462B2/en active Active
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2017
- 2017-08-31 JP JP2017166597A patent/JP6475298B2/ja active Active
- 2017-09-14 AU AU2017228656A patent/AU2017228656B2/en active Active
- 2017-12-20 US US15/849,233 patent/US10942172B2/en active Active
- 2017-12-20 US US15/848,719 patent/US10209245B2/en active Active
- 2017-12-20 US US15/849,196 patent/US10942171B2/en active Active
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2018
- 2018-07-23 JP JP2018137467A patent/JP6574879B2/ja active Active
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2019
- 2019-04-04 AU AU2019202353A patent/AU2019202353B2/en active Active
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2021
- 2021-03-08 US US17/195,416 patent/US20210263017A1/en active Pending
- 2021-06-03 AU AU2021203620A patent/AU2021203620A1/en active Pending
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