DK2438446T3 - Fremgangsmåder, reagenser og kits til flowcytometrisk immunfænotypebestemmelse - Google Patents

Fremgangsmåder, reagenser og kits til flowcytometrisk immunfænotypebestemmelse

Info

Publication number
DK2438446T3
DK2438446T3 DK10727985.3T DK10727985T DK2438446T3 DK 2438446 T3 DK2438446 T3 DK 2438446T3 DK 10727985 T DK10727985 T DK 10727985T DK 2438446 T3 DK2438446 T3 DK 2438446T3
Authority
DK
Denmark
Prior art keywords
kits
reagents
methods
flow cytometric
immunophenotype
Prior art date
Application number
DK10727985.3T
Other languages
English (en)
Inventor
De Matos Correia E Vale José Alberto Orfao
Juan Alejandro Flores-Montero
Der Velden Vincent Henricus Johannes Van
Sebastian Böttcher
Dongen Jacobus Johannes Maria Van
Ludovic Bernard Simon Lhermitte
Ester Mejstríková
Marta Marín Ayuso
Parra Julia Maria Almeida
Andrew Craig Rawstron
Tute Ruth Mary De
Vahid Asnafi
Tomasz Szczepanski
Da Silva Lucio Paulo Jorge Monteiro
Carlos Eduardo Pedreira
Original Assignee
Univ Erasmus Medical Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41259006&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2438446(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Erasmus Medical Ct filed Critical Univ Erasmus Medical Ct
Application granted granted Critical
Publication of DK2438446T3 publication Critical patent/DK2438446T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4915Blood using flow cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1402Data analysis by thresholding or gating operations performed on the acquired signals or stored data
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1413Hydrodynamic focussing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ecology (AREA)
  • Dispersion Chemistry (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DK10727985.3T 2009-06-03 2010-06-02 Fremgangsmåder, reagenser og kits til flowcytometrisk immunfænotypebestemmelse DK2438446T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09161870A EP2259065A1 (en) 2009-06-03 2009-06-03 Methods, reagents and kits for flow cytometric immunophenotyping
PCT/NL2010/050332 WO2010140885A1 (en) 2009-06-03 2010-06-02 Methods, reagents and kits for flow cytometric immunophenotyping

Publications (1)

Publication Number Publication Date
DK2438446T3 true DK2438446T3 (da) 2014-05-26

Family

ID=41259006

Family Applications (3)

Application Number Title Priority Date Filing Date
DK10727985.3T DK2438446T3 (da) 2009-06-03 2010-06-02 Fremgangsmåder, reagenser og kits til flowcytometrisk immunfænotypebestemmelse
DK17165543.4T DK3206031T3 (da) 2009-06-03 2010-06-02 Fremgangsmåder, reagenser og kit til strømningscytometrisk immunophenotyping
DK14158924.2T DK2743698T3 (da) 2009-06-03 2010-06-02 Fremgangsmåder, reagenser og kits til strømningscytometrisk immunfænotypebestemmelse

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK17165543.4T DK3206031T3 (da) 2009-06-03 2010-06-02 Fremgangsmåder, reagenser og kit til strømningscytometrisk immunophenotyping
DK14158924.2T DK2743698T3 (da) 2009-06-03 2010-06-02 Fremgangsmåder, reagenser og kits til strømningscytometrisk immunfænotypebestemmelse

Country Status (12)

Country Link
US (5) US9880158B2 (da)
EP (4) EP2259065A1 (da)
JP (4) JP5795308B2 (da)
AU (5) AU2010254680B2 (da)
CA (2) CA2764670C (da)
DK (3) DK2438446T3 (da)
ES (3) ES2724633T3 (da)
HU (1) HUE044269T2 (da)
PL (3) PL2438446T3 (da)
PT (2) PT3206031T (da)
TR (1) TR201906754T4 (da)
WO (1) WO2010140885A1 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2259065A1 (en) * 2009-06-03 2010-12-08 Erasmus University Medical Center Rotterdam Methods, reagents and kits for flow cytometric immunophenotyping
JP5791095B2 (ja) * 2010-12-10 2015-10-07 国立大学法人金沢大学 Pnh型白血球の検出方法
EP2495567A1 (en) * 2011-03-04 2012-09-05 Erasmus University Medical Center Rotterdam Methods and means for monitoring disruption of tissue homeostasis in the total body
US9777332B2 (en) 2011-03-31 2017-10-03 St. Jude Children's Research Hospital Methods and compositions for identifying minimal residual disease in acute lymphoblastic leukemia
ES2660429T3 (es) 2012-06-14 2018-03-22 Erasmus University Medical Center Rotterdam Métodos, reactivos y kits para detectar enfermedad residual mínima
CN103018463B (zh) * 2012-12-20 2015-08-05 北京大学人民医院 检测急性b淋巴细胞白血病相关免疫表型的试剂盒及其应用
CN107209101B (zh) 2014-10-30 2019-10-25 鹿特丹伊拉斯谟大学医疗中心 用于诊断原发性免疫缺陷的试剂、方法和试剂盒
CN105223361B (zh) * 2015-08-28 2017-05-17 北京大学人民医院 一种检测急性t淋巴细胞白血病幼稚t细胞的试剂盒、应用及方法
WO2017094008A1 (en) 2015-12-01 2017-06-08 The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center Improved cytometric assays
CN105606797B (zh) * 2016-01-15 2016-09-07 浙江博真生物科技有限公司 抗体组合物及其在白血病淋巴瘤分型中的应用
FR3051555B1 (fr) * 2016-05-20 2018-05-11 Horiba Abx Sas Detection de la maladie residuelle du myelome multiple
GB201617572D0 (en) 2016-10-17 2016-11-30 Ospedale San Raffaele Use, method, kit, composition and antibodies
EP3340107B9 (en) 2016-12-23 2021-07-21 Cytognos, S.L. Method of digital information classification
JP7084695B2 (ja) * 2017-03-28 2022-06-15 シスメックス株式会社 試薬選択支援装置、方法、プログラムおよび記録媒体並びに試料測定装置
WO2019046118A1 (en) * 2017-08-31 2019-03-07 Agilent Technologies, Inc. COMPOSITION FOR STABILIZING ANTIBODY FORMULATIONS CONTAINING PERCP
CN110716051B (zh) * 2018-07-13 2022-11-29 迈健医药科技无锡有限公司 一种免疫细胞全维分析方法
US10854040B1 (en) 2019-07-18 2020-12-01 Adp Gauselmann Gmbh Gaming system and method providing expanding symbols
NL2024163B1 (en) * 2019-11-05 2021-07-20 Univ Of Salamanca Means and methods for multiparameter cytometry-based leukocyte subsetting.
WO2021129976A1 (en) 2019-12-27 2021-07-01 Scailyte Ag Method for diagnosing cutaneous t-cell lymphoma diseases
WO2021231071A1 (en) * 2020-05-13 2021-11-18 Becton, Dickinson And Company Blood based controls for complex panel
WO2021251824A1 (en) 2020-06-10 2021-12-16 Stichting Euroflow Means and methods for the diagnosis, classification and/or monitoring of pediatric tumors.
CN112578117B (zh) * 2021-02-22 2021-05-25 信纳克(北京)生化标志物检测医学研究有限责任公司 抗体组合物及其筛查移植后淋巴细胞增殖性疾病的应用
CN112552407B (zh) * 2021-02-24 2021-05-25 信纳克(北京)生化标志物检测医学研究有限责任公司 抗体组合物及其在检测急性b淋巴细胞白血病中的应用
CN113188982B (zh) * 2021-04-30 2022-05-10 天津深析智能科技发展有限公司 淋巴细胞亚群自动分析中有效去除单核细胞干扰的方法
CN113777327B (zh) * 2021-09-13 2022-09-02 北京大学人民医院 用于白血病/淋巴瘤免疫分型初筛的抗体组合物及其应用
WO2023081320A1 (en) * 2021-11-04 2023-05-11 Orca Biosystems, Inc. Therapeutic compositions and methods for allogeneic hematopoietic stem cell transplantation
CN113933513B (zh) * 2021-12-15 2022-03-04 信纳克(北京)生化标志物检测医学研究有限责任公司 检测靶向治疗后急性t淋巴细胞白血病的试剂组合物及其应用
CN114264825B (zh) * 2021-12-22 2023-08-15 重庆医科大学附属儿童医院 一种b淋巴细胞发育亚群免疫分型的方法和试剂盒
CN114460311B (zh) * 2022-04-13 2022-07-05 北京大学人民医院 用于b-all/lbl免疫分型的试剂组合物及其应用
CN116593699B (zh) * 2023-07-13 2023-10-03 天津市肿瘤医院空港医院 应用于流式细胞术检测t细胞表面cd39分子的检测方法
CN118130798A (zh) * 2024-05-06 2024-06-04 北京大学人民医院 一种用于流式细胞检测急性t淋巴细胞白血病/淋巴瘤免疫表型的抗体组合及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047321A (en) 1988-06-15 1991-09-10 Becton Dickinson & Co. Method for analysis of cellular components of a fluid
US5234816A (en) * 1991-07-12 1993-08-10 Becton, Dickinson And Company Method for the classification and monitoring of leukemias
CA2087086A1 (en) 1992-01-22 1993-07-23 Leon Wmm Terstappen Multidimensional cell differential analysis
ES2051651B1 (es) 1992-12-10 1995-01-01 Univ Salamanca Procedimiento para la cuantificacion simultanea, en una sola medicion, de los principales tipos de linfocitos humanos y sus subpoblaciones.
US6761883B2 (en) * 1999-06-29 2004-07-13 The Board Of Trustees Of The Leland Stanford Junior University Mammalian myeloid progenitor cell subsets
ES2257524T3 (es) 2002-05-14 2006-08-01 Universidad De Salamanca Analisis multidimensional de la formula leucocitaria.
US7507548B2 (en) 2003-03-04 2009-03-24 University Of Salamanca Multidimensional detection of aberrant phenotypes in neoplastic cells to be used to monitor minimal disease levels using flow cytometry measurements
EP1627563A1 (en) * 2004-08-10 2006-02-22 Academisch Medisch Centrum bij de Universiteit van Amsterdam Means and methods for producing a stabilized cell of interest
JP2007105037A (ja) * 2005-09-16 2007-04-26 Univ Of Tokyo キメリズムを利用した幹細胞移植のための検査
US7321843B2 (en) 2005-09-30 2008-01-22 Universidad De Salamanca Method for generating new flow cytometry data files containing an infinite number of dimensions based on data estimation
JP2007263958A (ja) * 2006-02-28 2007-10-11 Nippon Medical Soken:Kk 血液細胞の分類法および診断ならびにそれを利用したテイラーメード治療および予防
EP2156178B1 (en) * 2007-04-02 2011-12-21 Acoustic Cytometry Systems, Inc. Methods for enhanced analysis of acoustic field focused cells and particles
EP2259065A1 (en) * 2009-06-03 2010-12-08 Erasmus University Medical Center Rotterdam Methods, reagents and kits for flow cytometric immunophenotyping

Also Published As

Publication number Publication date
JP2012529046A (ja) 2012-11-15
US10209245B2 (en) 2019-02-19
JP6207556B2 (ja) 2017-10-04
US20120165213A1 (en) 2012-06-28
PL3206031T3 (pl) 2019-08-30
ES2627952T3 (es) 2017-08-01
JP2017207519A (ja) 2017-11-24
EP3206031A2 (en) 2017-08-16
PT3206031T (pt) 2019-05-29
EP2438446A1 (en) 2012-04-11
US10942171B2 (en) 2021-03-09
AU2017228656A1 (en) 2017-10-05
US9880158B2 (en) 2018-01-30
AU2021203620A1 (en) 2021-07-01
US10942172B2 (en) 2021-03-09
EP2438446B1 (en) 2014-03-12
AU2010254680B2 (en) 2015-11-19
US20180120301A1 (en) 2018-05-03
EP2743698B1 (en) 2017-04-19
AU2019202353A1 (en) 2019-05-02
EP3206031A3 (en) 2017-10-25
PL2743698T3 (pl) 2017-09-29
ES2724633T3 (es) 2019-09-12
CA3044453C (en) 2022-10-04
TR201906754T4 (tr) 2019-05-21
DK2743698T3 (da) 2017-06-19
HUE044269T2 (hu) 2019-10-28
JP5795308B2 (ja) 2015-10-14
JP2015206802A (ja) 2015-11-19
CA3044453A1 (en) 2010-12-09
DK3206031T3 (da) 2019-05-20
JP6475298B2 (ja) 2019-02-27
US20180180598A1 (en) 2018-06-28
US20210263017A1 (en) 2021-08-26
EP2743698A3 (en) 2014-08-27
PT2438446E (pt) 2014-06-12
CA2764670C (en) 2019-07-02
ES2464736T3 (es) 2014-06-03
PL2438446T3 (pl) 2014-08-29
AU2010254680A1 (en) 2012-01-12
JP6574879B2 (ja) 2019-09-11
WO2010140885A1 (en) 2010-12-09
US20180180597A1 (en) 2018-06-28
AU2016200462A1 (en) 2016-02-18
CA2764670A1 (en) 2010-12-09
AU2019202353B2 (en) 2021-03-04
AU2017228656B2 (en) 2019-01-24
EP3206031B1 (en) 2019-02-20
JP2018163173A (ja) 2018-10-18
AU2016200462B2 (en) 2017-06-29
EP2259065A1 (en) 2010-12-08
EP2743698A2 (en) 2014-06-18

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