PT2385981T - Método para controlar peso molecular de polissacárido de streptococcus pneumoniae com a utilização de carbono. - Google Patents

Método para controlar peso molecular de polissacárido de streptococcus pneumoniae com a utilização de carbono.

Info

Publication number
PT2385981T
PT2385981T PT98040983T PT09804098T PT2385981T PT 2385981 T PT2385981 T PT 2385981T PT 98040983 T PT98040983 T PT 98040983T PT 09804098 T PT09804098 T PT 09804098T PT 2385981 T PT2385981 T PT 2385981T
Authority
PT
Portugal
Prior art keywords
carbon
molecular weight
streptococcus pneumoniae
pneumoniae polysaccharide
polysaccharide molecular
Prior art date
Application number
PT98040983T
Other languages
English (en)
Inventor
Heather Crinean Jean
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of PT2385981T publication Critical patent/PT2385981T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
PT98040983T 2008-12-18 2009-12-17 Método para controlar peso molecular de polissacárido de streptococcus pneumoniae com a utilização de carbono. PT2385981T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13857008P 2008-12-18 2008-12-18

Publications (1)

Publication Number Publication Date
PT2385981T true PT2385981T (pt) 2019-10-28

Family

ID=41666441

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98040983T PT2385981T (pt) 2008-12-18 2009-12-17 Método para controlar peso molecular de polissacárido de streptococcus pneumoniae com a utilização de carbono.

Country Status (19)

Country Link
US (4) US20100160622A1 (pt)
EP (1) EP2385981B1 (pt)
JP (2) JP5789514B2 (pt)
KR (1) KR101307703B1 (pt)
CN (1) CN102257127B (pt)
AU (1) AU2009335824B2 (pt)
BR (1) BRPI0923165A8 (pt)
CA (1) CA2743708C (pt)
DK (1) DK2385981T3 (pt)
ES (1) ES2749952T3 (pt)
HK (1) HK1163737A1 (pt)
HU (1) HUE046859T2 (pt)
IL (1) IL213215A (pt)
MX (1) MX346071B (pt)
PL (1) PL2385981T3 (pt)
PT (1) PT2385981T (pt)
RU (1) RU2524436C2 (pt)
SI (1) SI2385981T1 (pt)
WO (1) WO2010080484A1 (pt)

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CN101378778B (zh) 2005-12-22 2013-02-06 葛兰素史密丝克莱恩生物有限公司 肺炎球菌多糖缀合物疫苗
US8795689B2 (en) * 2008-12-18 2014-08-05 Wyeth Llc Method for controlling Streptococcus pneumoniae serotype 19A polysaccharide molecular weight
BRPI1014494A2 (pt) 2009-04-30 2016-08-02 Coley Pharm Group Inc vacina pneumocócica e usos da mesma
WO2011151841A1 (en) * 2010-05-31 2011-12-08 Panacea Biotec Limited Fermentation process for streptococcus pneumoniae
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
CA3048981A1 (en) 2016-12-30 2018-07-05 Sutrovax, Inc. Polypeptide-antigen conjugates with non-natural amino acids
WO2018144439A1 (en) 2017-01-31 2018-08-09 Merck Sharp & Dohme Corp. Methods for making polysaccharide-protein conjugates
CN110337307A (zh) 2017-02-24 2019-10-15 默沙东公司 增强肺炎链球菌多糖-蛋白缀合物的免疫原性
JP7218358B2 (ja) 2017-09-07 2023-02-06 メルク・シャープ・アンド・ドーム・エルエルシー 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用
CA3074703A1 (en) 2017-09-07 2019-03-14 Merck Sharp & Dohme Corp. Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates
CN107746825A (zh) * 2017-11-30 2018-03-02 成都欧林生物科技股份有限公司 利于肺炎链球菌快速增殖的培养基
CN108004160A (zh) * 2017-11-30 2018-05-08 成都欧林生物科技股份有限公司 含有中药材的菌种培养基的制备方法
JP7369123B2 (ja) 2017-12-06 2023-10-25 メルク・シャープ・アンド・ドーム・エルエルシー 肺炎球菌多糖類－タンパク質コンジュゲートを含む組成物およびその使用方法
KR20210005158A (ko) 2018-04-30 2021-01-13 머크 샤프 앤드 돔 코포레이션 스트렙토코쿠스 뉴모니아에 피막 폴리사카라이드 담체 단백질 접합체를 제조하는 방법
KR20210002641A (ko) 2018-04-30 2021-01-08 머크 샤프 앤드 돔 코포레이션 디메틸술폭시드 중의 동결건조된 돌연변이체 디프테리아 독소의 균질 용액을 제공하는 방법
CN113423815A (zh) * 2018-12-06 2021-09-21 创赏有限公司 非动物来源培养基上的细菌生长
MA54533A (fr) 2018-12-19 2022-03-30 Merck Sharp & Dohme Compositions comprenant des conjugués polysaccharide-protéine de streptococcus pneumoniae et leurs méthodes d'utilisation

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US4115058A (en) * 1977-10-03 1978-09-19 Fmc Corporation Aromatic sulfonic anhydrides as peroxygen activators
CA1115210A (en) 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
US4221906A (en) * 1979-03-19 1980-09-09 American Cyanamid Company Stabilization of pneumococcal polysaccharides
US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
FR2495939B1 (fr) 1980-12-11 1985-10-11 Merieux Inst Procede de purification de polyosides de streptococcus pneumoniae et vaccin a base de polyosides ainsi purifies
BE889979A (fr) 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4686102A (en) * 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
US5656206A (en) * 1995-06-14 1997-08-12 Transitions Optical, Inc. Substituted naphthopyrans
US6146902A (en) * 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
WO2001068903A1 (en) * 2000-03-16 2001-09-20 The Children's Hospital Of Philadelphia Modulating production of pneumococcal capsular polysaccharide
US6743610B2 (en) * 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
WO2004042006A2 (en) * 2002-10-31 2004-05-21 Diversa Corporation Amylases, nucleic acids encoding them and methods for making and using them
US7320874B2 (en) * 2003-07-08 2008-01-22 Aventis Pasteur Sa Assaying the teichoic acids of gram+ bacteria
PL1664319T3 (pl) * 2003-09-11 2010-07-30 De Staat Der Nederlanden Vert Door De Mini Van Vws Sposób wytwarzania polisacharydu otoczkowego do zastosowania w szczepionkach koniugatowych
US20070184072A1 (en) * 2005-04-08 2007-08-09 Wyeth Multivalent pneumococcal polysaccharide-protein conjugate composition
NZ562719A (en) 2005-04-08 2008-12-24 Wyeth Corp Separation of contaminants from streptococcus pneumoniae polysaccharide by pH manipulation
CN102716480B (zh) * 2005-04-08 2023-03-21 惠氏有限责任公司 多价肺炎球菌多糖-蛋白质缀合物组合物
US7955605B2 (en) * 2005-04-08 2011-06-07 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
GB0522303D0 (en) 2005-11-01 2005-12-07 Chiron Srl Culture method
US8481054B2 (en) * 2005-12-28 2013-07-09 The UAB Foundation Pneumococcal serotypes
RU2460539C2 (ru) * 2006-10-10 2012-09-10 Вайет СПОСОБ ОЧИСТКИ ПОЛИСАХАРИДОВ Streptococcus pneumoniae 3 ТИПА (ВАРИАНТЫ)
PL2129693T3 (pl) * 2007-03-23 2017-07-31 Wyeth Llc Skrócony sposób oczyszczania do wytwarzania polisacharydów otoczkowych Streptococcus pneumoniae
AU2008267208B2 (en) * 2007-06-26 2012-01-19 Glaxosmithkline Biologicals S.A. Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
US8795689B2 (en) * 2008-12-18 2014-08-05 Wyeth Llc Method for controlling Streptococcus pneumoniae serotype 19A polysaccharide molecular weight

Also Published As

Publication number Publication date
HUE046859T2 (hu) 2020-03-30
US20150376667A1 (en) 2015-12-31
BRPI0923165A8 (pt) 2017-09-12
JP2015144614A (ja) 2015-08-13
CN102257127A (zh) 2011-11-23
KR20110091548A (ko) 2011-08-11
CA2743708C (en) 2018-01-09
US20200323974A1 (en) 2020-10-15
JP2012512659A (ja) 2012-06-07
JP5789514B2 (ja) 2015-10-07
US11376315B2 (en) 2022-07-05
JP6095715B2 (ja) 2017-03-15
RU2011124143A (ru) 2013-01-27
IL213215A (en) 2017-08-31
BRPI0923165A2 (pt) 2016-02-10
PL2385981T3 (pl) 2020-01-31
IL213215A0 (en) 2011-07-31
SI2385981T1 (sl) 2019-11-29
AU2009335824A1 (en) 2010-07-15
US20100160622A1 (en) 2010-06-24
HK1163737A1 (en) 2012-09-14
MX2011006431A (es) 2011-07-19
EP2385981B1 (en) 2019-09-04
RU2524436C2 (ru) 2014-07-27
KR101307703B1 (ko) 2013-09-11
AU2009335824B2 (en) 2013-07-04
DK2385981T3 (da) 2019-10-21
US20170224802A1 (en) 2017-08-10
EP2385981A1 (en) 2011-11-16
CN102257127B (zh) 2014-01-01
ES2749952T3 (es) 2020-03-24
MX346071B (es) 2017-03-02
WO2010080484A1 (en) 2010-07-15
CA2743708A1 (en) 2010-07-15

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