DK2385981T3 - Fremgangsmåde til kontrol af molekylvægt af streptococcus pneumoniae-polysaccharid ved anvendelse af carbon - Google Patents

Fremgangsmåde til kontrol af molekylvægt af streptococcus pneumoniae-polysaccharid ved anvendelse af carbon Download PDF

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Publication number
DK2385981T3
DK2385981T3 DK09804098.3T DK09804098T DK2385981T3 DK 2385981 T3 DK2385981 T3 DK 2385981T3 DK 09804098 T DK09804098 T DK 09804098T DK 2385981 T3 DK2385981 T3 DK 2385981T3
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DK
Denmark
Prior art keywords
checking
procedure
carbon
molecular weight
streptococcus pneumoniae
Prior art date
Application number
DK09804098.3T
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English (en)
Inventor
Jean Heather Crinean
Original Assignee
Wyeth Llc
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Publication of DK2385981T3 publication Critical patent/DK2385981T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK09804098.3T 2008-12-18 2009-12-17 Fremgangsmåde til kontrol af molekylvægt af streptococcus pneumoniae-polysaccharid ved anvendelse af carbon DK2385981T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13857008P 2008-12-18 2008-12-18
PCT/US2009/068424 WO2010080484A1 (en) 2008-12-18 2009-12-17 Method for controlling streptococcus pneumoniae polysaccharide molecular weight using carbon

Publications (1)

Publication Number Publication Date
DK2385981T3 true DK2385981T3 (da) 2019-10-21

Family

ID=41666441

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09804098.3T DK2385981T3 (da) 2008-12-18 2009-12-17 Fremgangsmåde til kontrol af molekylvægt af streptococcus pneumoniae-polysaccharid ved anvendelse af carbon

Country Status (19)

Country Link
US (4) US20100160622A1 (da)
EP (1) EP2385981B1 (da)
JP (2) JP5789514B2 (da)
KR (1) KR101307703B1 (da)
CN (1) CN102257127B (da)
AU (1) AU2009335824B2 (da)
BR (1) BRPI0923165A8 (da)
CA (1) CA2743708C (da)
DK (1) DK2385981T3 (da)
ES (1) ES2749952T3 (da)
HK (1) HK1163737A1 (da)
HU (1) HUE046859T2 (da)
IL (1) IL213215A (da)
MX (1) MX346071B (da)
PL (1) PL2385981T3 (da)
PT (1) PT2385981T (da)
RU (1) RU2524436C2 (da)
SI (1) SI2385981T1 (da)
WO (1) WO2010080484A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2808919C (en) 2005-12-22 2016-04-19 Glaxosmithkline Biologicals S.A. Streptococcus pneumoniae capsular saccharide vaccine
KR20110091546A (ko) * 2008-12-18 2011-08-11 와이어쓰 엘엘씨 스트렙토코커스 뉴모니에 혈청형 19ａ 폴리사카라이드 분자량을 조절하는 방법
WO2010125480A1 (en) 2009-04-30 2010-11-04 Coley Pharmaceutical Group, Inc. Pneumococcal vaccine and uses thereof
WO2011151841A1 (en) * 2010-05-31 2011-12-08 Panacea Biotec Limited Fermentation process for streptococcus pneumoniae
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
WO2018126229A2 (en) 2016-12-30 2018-07-05 Sutrovax, Inc. Polypeptide-antigen conjugates with non-natural amino acids
CN116870144A (zh) 2017-01-31 2023-10-13 默沙东有限责任公司 制备多糖-蛋白缀合物的方法
BR112019017560A2 (pt) 2017-02-24 2020-04-07 Merck Sharp & Dohme intensificação da imunogenicidade dos conjugados de polissacarídeo-proteína de streptococcus pneumoniae
MX2020002557A (es) 2017-09-07 2020-07-13 Merck Sharp & Dohme Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina.
CN111065387B (zh) 2017-09-07 2023-08-25 默沙东有限责任公司 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途
CN107746825A (zh) * 2017-11-30 2018-03-02 成都欧林生物科技股份有限公司 利于肺炎链球菌快速增殖的培养基
CN108004160A (zh) * 2017-11-30 2018-05-08 成都欧林生物科技股份有限公司 含有中药材的菌种培养基的制备方法
GEP20227420B (en) 2017-12-06 2022-10-10 Merck Sharp & Dohme Llc Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
EP3787673A4 (en) 2018-04-30 2022-04-27 Merck Sharp & Dohme Corp. METHODS FOR PRODUCING CAPSULAR CARRIER PROTEIN-POLYSACCHARIDE CONJUGATES OF STREPTOCOCCUS PNEUMONIAE
US11896656B2 (en) 2018-04-30 2024-02-13 Merck Sharp & Dohme Llc Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide
CN113423815A (zh) * 2018-12-06 2021-09-21 创赏有限公司 非动物来源培养基上的细菌生长
JOP20210148A1 (ar) 2018-12-19 2023-01-30 Merck Sharp & Dohme تركيبات تشتمل على متقارنات بولي سكاريد-بروتين للمكورات العقدية الرئوية وطرق استخدامها

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115058A (en) * 1977-10-03 1978-09-19 Fmc Corporation Aromatic sulfonic anhydrides as peroxygen activators
CA1115210A (en) 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
US4221906A (en) * 1979-03-19 1980-09-09 American Cyanamid Company Stabilization of pneumococcal polysaccharides
US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
FR2495939B1 (fr) 1980-12-11 1985-10-11 Merieux Inst Procede de purification de polyosides de streptococcus pneumoniae et vaccin a base de polyosides ainsi purifies
BE889979A (fr) 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4686102A (en) * 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
US5656206A (en) * 1995-06-14 1997-08-12 Transitions Optical, Inc. Substituted naphthopyrans
US6146902A (en) * 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
KR100914702B1 (ko) * 2000-03-16 2009-08-28 더 칠드런스 호스피탈 오브 필라델피아 폐렴구균의 캡슐 다당류 생산의 조절 방법
US6743610B2 (en) * 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
WO2004042006A2 (en) * 2002-10-31 2004-05-21 Diversa Corporation Amylases, nucleic acids encoding them and methods for making and using them
US7320874B2 (en) * 2003-07-08 2008-01-22 Aventis Pasteur Sa Assaying the teichoic acids of gram+ bacteria
US7582459B2 (en) * 2003-09-11 2009-09-01 De Staat Der Nederlanden, Vert. Door De Minister Van Vws Process for producing a capsular polysaccharide for use in conjugate vaccines
CN102716480B (zh) * 2005-04-08 2023-03-21 惠氏有限责任公司 多价肺炎球菌多糖-蛋白质缀合物组合物
US7955605B2 (en) 2005-04-08 2011-06-07 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
JP5049264B2 (ja) 2005-04-08 2012-10-17 ワイス・エルエルシー ｐＨ操作によるストレプトコッカス・ニューモニエ多糖からの混入物の分離
US20070184072A1 (en) 2005-04-08 2007-08-09 Wyeth Multivalent pneumococcal polysaccharide-protein conjugate composition
GB0522303D0 (en) 2005-11-01 2005-12-07 Chiron Srl Culture method
US8481054B2 (en) * 2005-12-28 2013-07-09 The UAB Foundation Pneumococcal serotypes
CL2007002909A1 (es) * 2006-10-10 2008-04-18 Wyeth Corp Metodo para reduccion o extraccion de impurezas de proteinas a partir de lisado celular de streptoccocus pneumoniae que comprende calentar dicho lisado, separar a los precipitantes a partir de dicho lisado produciendo un lisado que contiene polisacar
HUE039169T2 (hu) * 2007-03-23 2018-12-28 Wyeth Llc Rövidített tisztítási eljárás Streptococcus pneumoniae tok-poliszacharidok elõállítására
EP2687228B1 (en) * 2007-06-26 2017-07-19 GlaxoSmithKline Biologicals S.A. Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
KR20110091546A (ko) * 2008-12-18 2011-08-11 와이어쓰 엘엘씨 스트렙토코커스 뉴모니에 혈청형 19ａ 폴리사카라이드 분자량을 조절하는 방법

Also Published As

Publication number Publication date
KR20110091548A (ko) 2011-08-11
SI2385981T1 (sl) 2019-11-29
IL213215A0 (en) 2011-07-31
AU2009335824A1 (en) 2010-07-15
CN102257127B (zh) 2014-01-01
RU2011124143A (ru) 2013-01-27
AU2009335824B2 (en) 2013-07-04
CN102257127A (zh) 2011-11-23
HUE046859T2 (hu) 2020-03-30
PL2385981T3 (pl) 2020-01-31
HK1163737A1 (en) 2012-09-14
ES2749952T3 (es) 2020-03-24
EP2385981A1 (en) 2011-11-16
JP2015144614A (ja) 2015-08-13
JP6095715B2 (ja) 2017-03-15
BRPI0923165A8 (pt) 2017-09-12
PT2385981T (pt) 2019-10-28
WO2010080484A1 (en) 2010-07-15
EP2385981B1 (en) 2019-09-04
IL213215A (en) 2017-08-31
MX2011006431A (es) 2011-07-19
CA2743708C (en) 2018-01-09
JP5789514B2 (ja) 2015-10-07
US11376315B2 (en) 2022-07-05
MX346071B (es) 2017-03-02
US20150376667A1 (en) 2015-12-31
RU2524436C2 (ru) 2014-07-27
US20100160622A1 (en) 2010-06-24
US20170224802A1 (en) 2017-08-10
CA2743708A1 (en) 2010-07-15
BRPI0923165A2 (pt) 2016-02-10
US20200323974A1 (en) 2020-10-15
KR101307703B1 (ko) 2013-09-11
JP2012512659A (ja) 2012-06-07

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