PL3027618T3 - Polimorf inhibitorów syk - Google Patents
Polimorf inhibitorów sykInfo
- Publication number
- PL3027618T3 PL3027618T3 PL14750289T PL14750289T PL3027618T3 PL 3027618 T3 PL3027618 T3 PL 3027618T3 PL 14750289 T PL14750289 T PL 14750289T PL 14750289 T PL14750289 T PL 14750289T PL 3027618 T3 PL3027618 T3 PL 3027618T3
- Authority
- PL
- Poland
- Prior art keywords
- polymorph
- syk inhibitors
- syk
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361860197P | 2013-07-30 | 2013-07-30 | |
EP14750289.2A EP3027618B1 (en) | 2013-07-30 | 2014-07-29 | Polymorph of syk inhibitors |
PCT/US2014/048733 WO2015017460A1 (en) | 2013-07-30 | 2014-07-29 | Polymorph of syk inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3027618T3 true PL3027618T3 (pl) | 2021-04-19 |
Family
ID=51301367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL14750289T PL3027618T3 (pl) | 2013-07-30 | 2014-07-29 | Polimorf inhibitorów syk |
Country Status (32)
Country | Link |
---|---|
US (4) | US20160168155A1 (pl) |
EP (1) | EP3027618B1 (pl) |
JP (1) | JP6230709B2 (pl) |
KR (1) | KR101810798B1 (pl) |
CN (1) | CN105452252A (pl) |
AP (1) | AP2016009008A0 (pl) |
AR (1) | AR097158A1 (pl) |
AU (2) | AU2014296308C1 (pl) |
CA (1) | CA2919661C (pl) |
CL (1) | CL2016000238A1 (pl) |
CR (1) | CR20160098A (pl) |
DK (1) | DK3027618T3 (pl) |
EA (2) | EA029281B1 (pl) |
ES (1) | ES2822285T3 (pl) |
HK (1) | HK1222390A1 (pl) |
HR (1) | HRP20201582T1 (pl) |
HU (1) | HUE052090T2 (pl) |
IL (1) | IL243579A0 (pl) |
MD (1) | MD4659B1 (pl) |
MX (1) | MX2016001304A (pl) |
MY (1) | MY176803A (pl) |
NZ (1) | NZ715776A (pl) |
PE (1) | PE20160862A1 (pl) |
PH (1) | PH12016500169A1 (pl) |
PL (1) | PL3027618T3 (pl) |
PT (1) | PT3027618T (pl) |
SG (1) | SG11201600385TA (pl) |
SI (1) | SI3027618T1 (pl) |
SV (1) | SV2016005149A (pl) |
TW (1) | TW201602108A (pl) |
UY (1) | UY35683A (pl) |
WO (1) | WO2015017460A1 (pl) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102307581B (zh) | 2008-12-08 | 2016-08-17 | 吉利德康涅狄格股份有限公司 | 咪唑并哌嗪syk抑制剂 |
NZ602362A (en) | 2010-03-11 | 2014-11-28 | Gilead Connecticut Inc | Imidazopyridines syk inhibitors |
MX2016001480A (es) | 2013-07-30 | 2017-01-05 | Gilead Connecticut Inc | Formulacion de inhibidores de syk. |
MY176803A (en) | 2013-07-30 | 2020-08-21 | Gilead Connecticut Inc | Polymorph of syk inhibitors |
EA201690608A1 (ru) | 2013-12-04 | 2016-12-30 | Джилид Сайэнс, Инк. | Способы лечения раковых заболеваний |
US9290505B2 (en) | 2013-12-23 | 2016-03-22 | Gilead Sciences, Inc. | Substituted imidazo[1,2-a]pyrazines as Syk inhibitors |
TWI662037B (zh) | 2013-12-23 | 2019-06-11 | 美商基利科學股份有限公司 | 脾酪胺酸激酶抑制劑 |
CN106687139A (zh) * | 2014-07-14 | 2017-05-17 | 吉利德科学公司 | 用于治疗癌症的组合 |
TW201639573A (zh) | 2015-02-03 | 2016-11-16 | 吉李德科學股份有限公司 | 有關治療癌症之合併治療 |
EA201791946A1 (ru) | 2015-04-21 | 2018-03-30 | Джилид Сайэнс, Инк. | Лечение хронической реакции "трансплантат против хозяина" с применением ингибиторов syk |
US20170173034A1 (en) | 2015-12-17 | 2017-06-22 | Gilead Sciences, Inc. | Combination of a jak inhibitor and a syk inhibitor for treating cancers and inflammatory disorders |
WO2017144010A1 (zh) * | 2016-02-26 | 2017-08-31 | 苏州晶云药物科技有限公司 | (6-(1H-吲唑-6-基)-N-[4-(4-吗啉基)苯基]咪唑并[1,2-a]吡嗪-8-胺)甲磺酸盐的新晶型 |
TW201822764A (zh) | 2016-09-14 | 2018-07-01 | 美商基利科學股份有限公司 | Syk抑制劑 |
EP3512519A1 (en) | 2016-09-14 | 2019-07-24 | Gilead Sciences, Inc. | Syk inhibitors |
JOP20180040A1 (ar) | 2017-04-20 | 2019-01-30 | Gilead Sciences Inc | مثبطات pd-1/pd-l1 |
WO2018195471A1 (en) | 2017-04-21 | 2018-10-25 | Gilead Sciences, Inc. | Syk inhibitors in combination with hypomethylating agents |
AU2018321264A1 (en) * | 2017-08-25 | 2020-02-27 | Kronos Bio, Inc. | Polymorphs of Syk inhibitors |
JP7062792B2 (ja) | 2018-02-13 | 2022-05-06 | ギリアード サイエンシーズ, インコーポレイテッド | Pd-1/pd-l1阻害剤 |
WO2019204609A1 (en) | 2018-04-19 | 2019-10-24 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
MX2020012137A (es) | 2018-05-14 | 2021-01-29 | Gilead Sciences Inc | Inhibidores de mcl-1. |
CN112399874B (zh) | 2018-07-13 | 2024-03-22 | 吉利德科学公司 | Pd-1/pd-l1抑制剂 |
KR102635333B1 (ko) | 2018-10-24 | 2024-02-15 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
MX2021010131A (es) | 2019-02-22 | 2021-11-18 | Kronos Bio Inc | Formas sólidas de pirazinas condensadas a manera de inhibidores de syk. |
CN113402506B (zh) * | 2021-06-17 | 2023-06-16 | 四川大学 | 中间体和制备方法及其在合成长春布宁上的应用 |
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MY176803A (en) | 2013-07-30 | 2020-08-21 | Gilead Connecticut Inc | Polymorph of syk inhibitors |
MX2016001480A (es) | 2013-07-30 | 2017-01-05 | Gilead Connecticut Inc | Formulacion de inhibidores de syk. |
WO2015017610A1 (en) | 2013-07-31 | 2015-02-05 | Gilead Sciences, Inc. | Syk inhibitors |
EA201690608A1 (ru) | 2013-12-04 | 2016-12-30 | Джилид Сайэнс, Инк. | Способы лечения раковых заболеваний |
TWI662037B (zh) | 2013-12-23 | 2019-06-11 | 美商基利科學股份有限公司 | 脾酪胺酸激酶抑制劑 |
US9440991B2 (en) | 2013-12-23 | 2016-09-13 | Gilead Sciences, Inc. | Synthesis of an antiviral compound |
US9290505B2 (en) | 2013-12-23 | 2016-03-22 | Gilead Sciences, Inc. | Substituted imidazo[1,2-a]pyrazines as Syk inhibitors |
CN106687139A (zh) | 2014-07-14 | 2017-05-17 | 吉利德科学公司 | 用于治疗癌症的组合 |
TW201617074A (zh) | 2014-07-14 | 2016-05-16 | 吉李德科學股份有限公司 | Syk(脾酪胺酸激酶)抑制劑 |
TW201639573A (zh) * | 2015-02-03 | 2016-11-16 | 吉李德科學股份有限公司 | 有關治療癌症之合併治療 |
EA201791946A1 (ru) | 2015-04-21 | 2018-03-30 | Джилид Сайэнс, Инк. | Лечение хронической реакции "трансплантат против хозяина" с применением ингибиторов syk |
-
2014
- 2014-07-29 MY MYPI2016700285A patent/MY176803A/en unknown
- 2014-07-29 SI SI201431675T patent/SI3027618T1/sl unknown
- 2014-07-29 WO PCT/US2014/048733 patent/WO2015017460A1/en active Application Filing
- 2014-07-29 MD MD20160017A patent/MD4659B1/ro not_active IP Right Cessation
- 2014-07-29 AU AU2014296308A patent/AU2014296308C1/en not_active Ceased
- 2014-07-29 PL PL14750289T patent/PL3027618T3/pl unknown
- 2014-07-29 SG SG11201600385TA patent/SG11201600385TA/en unknown
- 2014-07-29 TW TW103125870A patent/TW201602108A/zh unknown
- 2014-07-29 HU HUE14750289A patent/HUE052090T2/hu unknown
- 2014-07-29 JP JP2016531837A patent/JP6230709B2/ja active Active
- 2014-07-29 NZ NZ715776A patent/NZ715776A/en not_active IP Right Cessation
- 2014-07-29 MX MX2016001304A patent/MX2016001304A/es unknown
- 2014-07-29 EA EA201690172A patent/EA029281B1/ru active IP Right Revival
- 2014-07-29 CA CA2919661A patent/CA2919661C/en active Active
- 2014-07-29 KR KR1020167005206A patent/KR101810798B1/ko active IP Right Grant
- 2014-07-29 CN CN201480043503.5A patent/CN105452252A/zh active Pending
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