PL2900269T3 - Połączenie regorafenibu i kwasu acetylosalicylowego do leczenia raka jelita grubego - Google Patents

Połączenie regorafenibu i kwasu acetylosalicylowego do leczenia raka jelita grubego

Info

Publication number
PL2900269T3
PL2900269T3 PL13770659T PL13770659T PL2900269T3 PL 2900269 T3 PL2900269 T3 PL 2900269T3 PL 13770659 T PL13770659 T PL 13770659T PL 13770659 T PL13770659 T PL 13770659T PL 2900269 T3 PL2900269 T3 PL 2900269T3
Authority
PL
Poland
Prior art keywords
regorafenib
combination
colorectal cancer
acetylsalicylic acid
treating colorectal
Prior art date
Application number
PL13770659T
Other languages
English (en)
Inventor
Olaf Weber
Karl Ziegelbauer
Original Assignee
Bayer Pharma Aktiengesellschaft
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46963566&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2900269(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Pharma Aktiengesellschaft, Bayer Ag filed Critical Bayer Pharma Aktiengesellschaft
Publication of PL2900269T3 publication Critical patent/PL2900269T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/612Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PL13770659T 2012-09-25 2013-09-23 Połączenie regorafenibu i kwasu acetylosalicylowego do leczenia raka jelita grubego PL2900269T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12185852 2012-09-25
PCT/EP2013/069735 WO2014048881A1 (en) 2012-09-25 2013-09-23 Combination of regorafenib and acetylsalicylic acid for treating cancer
EP13770659.4A EP2900269B1 (en) 2012-09-25 2013-09-23 Combination of regorafenib and acetylsalicylic acid for treating colorectal cancer

Publications (1)

Publication Number Publication Date
PL2900269T3 true PL2900269T3 (pl) 2019-02-28

Family

ID=46963566

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13770659T PL2900269T3 (pl) 2012-09-25 2013-09-23 Połączenie regorafenibu i kwasu acetylosalicylowego do leczenia raka jelita grubego

Country Status (29)

Country Link
US (1) US10898500B2 (pl)
EP (1) EP2900269B1 (pl)
JP (1) JP6294888B2 (pl)
KR (1) KR102210575B1 (pl)
CN (1) CN104994876A (pl)
AU (1) AU2013322854B2 (pl)
BR (1) BR112015006686B1 (pl)
CA (1) CA2885688C (pl)
CL (1) CL2015000744A1 (pl)
CY (1) CY1120939T1 (pl)
DK (1) DK2900269T3 (pl)
EA (1) EA032023B1 (pl)
ES (1) ES2687985T3 (pl)
HK (1) HK1214169A1 (pl)
HR (1) HRP20181462T1 (pl)
HU (1) HUE039878T2 (pl)
IL (1) IL237690B (pl)
LT (1) LT2900269T (pl)
MX (1) MX357035B (pl)
MY (1) MY183969A (pl)
NZ (1) NZ705860A (pl)
PH (1) PH12015500587A1 (pl)
PL (1) PL2900269T3 (pl)
PT (1) PT2900269T (pl)
RS (1) RS57875B1 (pl)
SG (2) SG10201702356VA (pl)
SI (1) SI2900269T1 (pl)
WO (1) WO2014048881A1 (pl)
ZA (1) ZA201502840B (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201407534PA (en) 2012-06-13 2014-12-30 Hoffmann La Roche New diazaspirocycloalkane and azaspirocycloalkane
IN2015DN00960A (pl) 2012-09-25 2015-06-12 Hoffmann La Roche
AR095079A1 (es) 2013-03-12 2015-09-16 Hoffmann La Roche Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
MY187449A (en) 2013-11-26 2021-09-22 Hoffmann La Roche New octahydro-cyclobuta [1,2-c;3,4-c']dipyrrol-2-yl
HUE046820T2 (hu) 2014-03-26 2020-03-30 Hoffmann La Roche Biciklusos vegyületek autotaxin (ATX) és lizofoszfatidsav (LPA) termelésgátlókként
JP6554481B2 (ja) 2014-03-26 2019-07-31 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft オートタキシン(atx)及びリゾホスファチジン酸(lpa)産生の阻害剤としての縮合[1,4]ジアゼピン化合物
CN103923001B (zh) * 2014-04-30 2016-02-10 药源药物化学(上海)有限公司 瑞戈非尼盐及其晶型、制备方法
MA41898A (fr) 2015-04-10 2018-02-13 Hoffmann La Roche Dérivés de quinazolinone bicyclique
CR20180058A (es) 2015-09-04 2018-02-26 Hoffmann La Roche Nuevos derivados de fenoximetilo
CN105267167A (zh) * 2015-09-11 2016-01-27 江苏嘉逸医药有限公司 一种瑞戈非尼口服固体药物组合物的制备方法
MX2017015034A (es) 2015-09-24 2018-04-13 Hoffmann La Roche Nuevos compuestos biciclicos como inhibidores duales de autotaxina (atx)/anhidrasa carbonica (ca).
KR20180054830A (ko) 2015-09-24 2018-05-24 에프. 호프만-라 로슈 아게 오토탁신(atx) 억제제로서의 이환형 화합물
MX2018001890A (es) 2015-09-24 2018-06-20 Hoffmann La Roche Compuestos biciclicos como inhibidores de autotaxina (atx).
CN107922415B (zh) 2015-09-24 2022-04-15 豪夫迈·罗氏有限公司 新的作为双重atx/ca抑制剂的二环化合物
ES2897981T3 (es) * 2016-06-28 2022-03-03 Asamedic As Composición de dos componentes que comprende ácido acetilsalicílico
WO2018167113A1 (en) 2017-03-16 2018-09-20 F. Hoffmann-La Roche Ag New bicyclic compounds as atx inhibitors
CR20190423A (es) 2017-03-16 2019-11-01 Hoffmann La Roche Nuevos compuestos biciclícos como inhibidores dobles de atx/ca
CA3065125A1 (en) * 2017-06-02 2018-12-06 Bayer Aktiengesellschaft Combination of regorafenib and pd-1/pd-l1(2) inhibitors for treating cancer
EP3501522A1 (en) 2017-12-22 2019-06-26 Asamedic AS Compositions comprising acetylsalicylic acid and a phosphate salt
EP3501523A1 (en) 2017-12-22 2019-06-26 Asamedic AS Two-component compositions comprising acetyl salicylic acid and a carbonate salt
KR20210156389A (ko) 2020-06-17 2021-12-27 재단법인대구경북과학기술원 레고라페닙을 유효성분으로 포함하는 염증질환의 예방 또는 치료용 약학적 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1197228A4 (en) * 1999-07-02 2004-03-10 Hisamitsu Pharmaceutical Co DRUG COMPOSITIONS FOR THE TREATMENT OF COLORECTAL CANCER
US20040121004A1 (en) * 2002-12-20 2004-06-24 Rajneesh Taneja Dosage forms containing a PPI, NSAID, and buffer
UA84156C2 (ru) * 2003-07-23 2008-09-25 Байер Фармасьютикалс Корпорейшн Фторозамещённая омега-карбоксиарилдифенилмочевина для лечения и профилактики болезней и состояний
WO2007054303A2 (en) * 2005-11-10 2007-05-18 Bayer Healthcare Ag Diaryl urea for treating diabetic neuropathy
AR062927A1 (es) 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
GB201002530D0 (en) * 2010-02-15 2010-03-31 Univ Wolverhampton The Di-aspirin derivatives
AR081060A1 (es) 2010-04-15 2012-06-06 Bayer Schering Pharma Ag Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida

Also Published As

Publication number Publication date
EA201500365A1 (ru) 2015-08-31
LT2900269T (lt) 2018-11-12
JP6294888B2 (ja) 2018-03-14
NZ705860A (en) 2018-07-27
US10898500B2 (en) 2021-01-26
ES2687985T3 (es) 2018-10-30
IL237690A0 (en) 2015-05-31
US20150202214A1 (en) 2015-07-23
CA2885688C (en) 2021-03-02
PH12015500587A1 (en) 2015-05-11
CA2885688A1 (en) 2014-04-03
AU2013322854A1 (en) 2015-04-02
EP2900269A1 (en) 2015-08-05
SG11201501963RA (en) 2015-04-29
ZA201502840B (en) 2017-11-29
RS57875B1 (sr) 2018-12-31
SI2900269T1 (sl) 2018-10-30
DK2900269T3 (en) 2018-10-01
MX357035B (es) 2018-06-25
IL237690B (en) 2019-07-31
HRP20181462T1 (hr) 2018-11-02
WO2014048881A1 (en) 2014-04-03
BR112015006686A2 (pt) 2019-08-27
CN104994876A (zh) 2015-10-21
BR112015006686B1 (pt) 2022-04-05
PT2900269T (pt) 2018-10-22
EA032023B1 (ru) 2019-03-29
MY183969A (en) 2021-03-17
SG10201702356VA (en) 2017-04-27
CY1120939T1 (el) 2019-12-11
KR20150060869A (ko) 2015-06-03
HUE039878T2 (hu) 2019-02-28
JP2015529234A (ja) 2015-10-05
KR102210575B1 (ko) 2021-02-02
CL2015000744A1 (es) 2016-01-08
MX2015003728A (es) 2015-09-23
HK1214169A1 (zh) 2016-07-22
AU2013322854B2 (en) 2018-07-19
EP2900269B1 (en) 2018-08-01

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