PL2845905T3 - Wytwarzanie oligosacharydów - Google Patents

Wytwarzanie oligosacharydów

Info

Publication number
PL2845905T3
PL2845905T3 PL13183670T PL13183670T PL2845905T3 PL 2845905 T3 PL2845905 T3 PL 2845905T3 PL 13183670 T PL13183670 T PL 13183670T PL 13183670 T PL13183670 T PL 13183670T PL 2845905 T3 PL2845905 T3 PL 2845905T3
Authority
PL
Poland
Prior art keywords
oligosaccharides
production
Prior art date
Application number
PL13183670T
Other languages
English (en)
Inventor
Stefan Jennewein
Original Assignee
Chr. Hansen HMO GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49117764&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2845905(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chr. Hansen HMO GmbH filed Critical Chr. Hansen HMO GmbH
Publication of PL2845905T3 publication Critical patent/PL2845905T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • C07H1/06Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/72Expression systems using regulatory sequences derived from the lac-operon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/12Disaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/14Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/20Preparation of compounds containing saccharide radicals produced by the action of an exo-1,4 alpha-glucosidase, e.g. dextrose
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/101Plasmid DNA for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
PL13183670T 2013-09-10 2013-09-10 Wytwarzanie oligosacharydów PL2845905T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13183670.2A EP2845905B8 (en) 2013-09-10 2013-09-10 Production of oligosaccharides

Publications (1)

Publication Number Publication Date
PL2845905T3 true PL2845905T3 (pl) 2021-09-27

Family

ID=49117764

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13183670T PL2845905T3 (pl) 2013-09-10 2013-09-10 Wytwarzanie oligosacharydów

Country Status (11)

Country Link
US (3) US11427845B2 (pl)
EP (3) EP3572521A1 (pl)
JP (3) JP6894703B2 (pl)
KR (1) KR102335067B1 (pl)
CN (3) CN110643658A (pl)
AU (1) AU2014320757C1 (pl)
BR (1) BR112016005228A8 (pl)
DK (1) DK2845905T3 (pl)
ES (1) ES2875327T3 (pl)
PL (1) PL2845905T3 (pl)
WO (1) WO2015036138A1 (pl)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2845905T3 (da) * 2013-09-10 2021-06-14 Chr Hansen Hmo Gmbh Fremstilling af oligosaccharider
EP2896628B1 (en) * 2014-01-20 2018-09-19 Jennewein Biotechnologie GmbH Process for efficient purification of neutral human milk oligosaccharides (HMOs) from microbial fermentation
US10588917B2 (en) 2015-03-31 2020-03-17 Glycom A/S Mixtures of human milk oligosaccharides comprising 3 ′-O-sialyllactose
US10829508B2 (en) 2015-12-18 2020-11-10 Glycom A/S Fermentative production of oligosaccharides
US11312741B2 (en) 2016-04-19 2022-04-26 Glycom A/S Separation of oligosaccharides from fermentation broth
WO2017221208A1 (en) 2016-06-24 2017-12-28 Glycom A/S Compositions comprising hmos, their production and use for the prevention and/or treatment of viral and/or bacterial infections
CN106190938B (zh) * 2016-07-18 2019-05-14 南开大学 一种构建的重组大肠杆菌及生物合成3’-唾液乳糖的方法
SG11201811807XA (en) * 2016-07-28 2019-02-27 Fonterra Cooperative Group Ltd Dairy product and process
WO2018053535A1 (en) * 2016-09-19 2018-03-22 Prolacta Bioscience, Inc. Purified human milk oligosaccharides compositions
PL3315610T3 (pl) * 2016-10-29 2021-06-14 Jennewein Biotechnologie Gmbh Sposób wytwarzania fukozylowanych oligosacharydów
EP3821712B1 (en) 2017-01-13 2022-11-09 Chr. Hansen A/S Fermented milk product obtained by an improved process
JP2018140968A (ja) * 2017-02-28 2018-09-13 日本食品化工株式会社 1,6−アンヒドロ−β−D−グルコフラノース含有糖質の製造方法
WO2019003136A1 (en) 2017-06-30 2019-01-03 Glycom A/S SYNTHESIS OF OLIGOSACCHARIDES
EP3425052A1 (en) 2017-07-07 2019-01-09 Jennewein Biotechnologie GmbH Fucosyltransferases and their use in producing fucosylated oligosaccharides
CN110914284A (zh) 2017-07-12 2020-03-24 格礼卡姆股份公司 包含中性单糖或寡糖和酸性非碳水化合物组分的无定形混合物
WO2019110803A1 (en) 2017-12-08 2019-06-13 Jennewein Biotechnologie Gmbh Spray-dried sialyllactose
EP3494805A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried tetrasaccharides
EP3524067A1 (en) 2018-02-08 2019-08-14 Jennewein Biotechnologie GmbH Spray-dried mixture of human milk oligosaccharides
EP3494807A1 (en) 2017-12-11 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried sialyllactose
EP3494806A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried lacto-n-fucopentaose
EP3494804A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried 3-fucosyllactose
WO2019215073A1 (en) * 2018-05-07 2019-11-14 Jennewein Biotechnologie Gmbh A SIMPLE METHOD FOR THE PURIFICATION OF LACTO-N-NEOTETRAOSE (LNnT) FROM CARBOHYDRATES OBTAINED BY MICROBIAL FERMENTATION
EP3569713A1 (en) 2018-05-16 2019-11-20 Jennewein Biotechnologie GmbH Use of glycosidases in the production of oligosaccharides
KR20210013138A (ko) * 2018-05-23 2021-02-03 디에스엠 아이피 어셋츠 비.브이. 올리고당의 제조
US10519475B1 (en) * 2018-11-21 2019-12-31 Amyris, Inc. Biosynthesis of compounds in yeast
DK3897902T3 (en) * 2018-12-19 2023-11-27 Glycom As Separation of oligosaccharides
CN109735479B (zh) * 2019-01-30 2022-04-01 光明乳业股份有限公司 一种合成2’-岩藻糖基乳糖的重组枯草芽孢杆菌及其构建方法与应用
EP4012026A4 (en) * 2019-05-21 2023-11-15 Korea University Research and Business Foundation USE OF AN ENZYME; THAT CLIPS BOTH ALPHA-ACE AND BETA-1,4-GLYCOSIDIIC BONDS
EP4286014A3 (en) * 2019-06-04 2024-02-21 N.V. Nutricia Nutritional composition comprising 2'fucosyllactose and 3'galactosyllactose
WO2021061991A1 (en) 2019-09-24 2021-04-01 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases
CA3188645A1 (en) 2020-08-14 2022-02-17 Prolacta Bioscience, Inc. Human milk oligosaccharide compositions for use with bacteriotherapies
EP4277634A1 (en) 2021-01-12 2023-11-22 Prolacta Bioscience, Inc. Synbiotic treatment regimens
DK202101233A1 (en) 2021-12-21 2023-06-27 Dsm Ip Assets Bv Crystallization of LNnT
CN114107342B (zh) * 2021-12-27 2024-01-26 黄山同兮生物科技有限公司 一种去除发酵液中乳糖的方法
KR102616020B1 (ko) 2021-12-31 2023-12-22 매일유업 주식회사 모유 올리고당 혼합물을 유효성분으로 포함하는 장관면역 개선용, 장 염증 예방 또는 개선용 조성물
CN116042562B (zh) * 2022-03-11 2023-10-20 山东恒鲁生物科技有限公司 重组酵母菌及其应用
CN115011535A (zh) * 2022-05-10 2022-09-06 南通励成生物工程有限公司 一种以葡萄糖为碳源合成2’-岩藻糖基乳糖的菌株及其构建方法和应用
KR20240002283A (ko) * 2022-06-28 2024-01-05 주식회사 삼양사 2’-푸코실락토오스 제조방법
WO2024042235A1 (en) 2022-08-25 2024-02-29 Dsm Ip Assets B.V. Hybrid method for producing complex hmos

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5995895A (ja) * 1982-11-22 1984-06-02 Meiji Seika Kaisha Ltd フラクトオリゴ糖の精製法
JPS6391092A (ja) 1986-10-07 1988-04-21 Yakult Honsha Co Ltd オリゴ糖の製造法
JPH05276969A (ja) * 1992-04-03 1993-10-26 Nippon Shinyaku Co Ltd 高純度マルトオリゴ糖の製法
JPH07274990A (ja) * 1994-04-15 1995-10-24 Mitsubishi Kasei Eng Co 環状イヌロオリゴ糖の精製方法
JP3095643B2 (ja) * 1994-11-17 2000-10-10 明治製菓株式会社 高濃度糖混合液からの高純度オリゴ糖類の製造法
KR100877278B1 (ko) * 2000-11-16 2009-01-07 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 α-이소말토실 전이효소 활성을 가진 폴리펩티드
EP1789570A2 (en) * 2004-09-17 2007-05-30 Neose Technologies, Inc. Production of oligosaccharides by microorganisms
RU2475759C2 (ru) 2007-04-16 2013-02-20 Момента Фармасьютикалз, Инк. Исследование n-гликанов с использованием экзогликозидаз
KR100945306B1 (ko) 2007-12-31 2010-03-03 주식회사 삼양제넥스 고순도 갈락토올리고당의 제조방법
US9139856B2 (en) * 2008-03-12 2015-09-22 Tata Chemicals Ltd. Process for production of galactooligosaccharides (GOS)
SG171814A1 (en) 2008-12-19 2011-07-28 Jennewein Biotechnologie Gmbh Synthesis of fucosylated compounds
ES2660698T3 (es) 2009-06-08 2018-03-23 Jennewein Biotechnologie Gmbh Síntesis de HMO
IT1395068B1 (it) * 2009-08-07 2012-09-05 Inalco Spa Processo per la produzione di galatto-oligosaccaridi ultrapuri
CN101870992A (zh) * 2010-06-21 2010-10-27 天津科技大学 利用基因工程菌耦合发酵合成gdp-岩藻糖的方法
ES2663627T3 (es) 2010-10-11 2018-04-16 Jennewein Biotechnologie Gmbh Fucosiltransferasas novedosas y sus aplicaciones
DK2479263T3 (da) * 2011-01-20 2014-02-03 Jennewein Biotechnologie Gmbh Nye fucosyltransferaser og deres anvendelser
CA3098403C (en) * 2011-02-16 2022-05-10 Glycosyn LLC Biosynthesis of human milk oligosaccharides in engineered bacteria
AU2012257395A1 (en) * 2011-05-13 2013-12-12 Glycom A/S Method for generating human milk oligosaccharides (HMOs) or precursors thereof
EP2728009B1 (en) * 2012-10-31 2017-07-26 Jennewein Biotechnologie GmbH Process for producing monosaccharides
DK2845905T3 (da) * 2013-09-10 2021-06-14 Chr Hansen Hmo Gmbh Fremstilling af oligosaccharider

Also Published As

Publication number Publication date
WO2015036138A1 (en) 2015-03-19
US20160186223A1 (en) 2016-06-30
AU2014320757C1 (en) 2018-07-19
EP3572521A1 (en) 2019-11-27
US11427845B2 (en) 2022-08-30
DK2845905T3 (da) 2021-06-14
US20220403433A1 (en) 2022-12-22
JP6894703B2 (ja) 2021-06-30
US20220389468A1 (en) 2022-12-08
AU2014320757A1 (en) 2016-04-28
EP3572520A1 (en) 2019-11-27
KR102335067B1 (ko) 2021-12-03
JP7389584B2 (ja) 2023-11-30
ES2875327T3 (es) 2021-11-10
KR20160065111A (ko) 2016-06-08
AU2014320757B2 (en) 2018-04-19
CN110628842A (zh) 2019-12-31
BR112016005228A2 (pl) 2017-09-05
JP6992029B2 (ja) 2022-01-13
EP2845905B1 (en) 2021-05-19
BR112016005228A8 (pt) 2022-11-08
JP2019213553A (ja) 2019-12-19
CN110643658A (zh) 2020-01-03
EP2845905A1 (en) 2015-03-11
JP2016530888A (ja) 2016-10-06
JP2019213552A (ja) 2019-12-19
EP2845905B8 (en) 2021-07-14
CN105722991A (zh) 2016-06-29

Similar Documents

Publication Publication Date Title
PL2845905T3 (pl) Wytwarzanie oligosacharydów
GB201314084D0 (en) Production of graphene
GB2511914B (en) Object production
EP2958881A4 (en) PREPARATION OF HIGHER ALCOHOLS
GB201322798D0 (en) Production system
DK3041946T3 (da) Fermentative production of oligosaccharides
GB201401248D0 (en) Method of manufacture
GB201517764D0 (en) Simulation of production systems
EP3041947A4 (en) Fermentative production of oligosaccharides
SG11201504608SA (en) Production of para-xylene
IL240742A0 (en) Methods for generating libraries for directed evolution
EP2971207A4 (en) PRODUCTION OF ALUMINUM-SCANDIUM ALLOYS
GB201414400D0 (en) Object production
PL3041945T3 (pl) Wytwarzanie galakto-oligosacharydów
EP2960338A4 (en) SUGAR SOLUTION PROCESS
EP2985113A4 (en) PRODUCTION PLANT
EP2981162A4 (en) PRODUCTION EQUIPMENT
GB201305231D0 (en) Method of Manufacture
EP2868476A4 (en) PROCESS FOR PRODUCING PRINTED MEDIA
ZA201602318B (en) Can end production
GB201707235D0 (en) Production of butanol
PT3027732T (pt) Métodos para a produção de biomassa de diatomácea
GB201322303D0 (en) Production process
EP3043646A4 (en) Methods of making 2-halonicotinonitriles
GB201303595D0 (en) Production of butanol