PL233786A1 - - Google Patents
Info
- Publication number
- PL233786A1 PL233786A1 PL23378681A PL23378681A PL233786A1 PL 233786 A1 PL233786 A1 PL 233786A1 PL 23378681 A PL23378681 A PL 23378681A PL 23378681 A PL23378681 A PL 23378681A PL 233786 A1 PL233786 A1 PL 233786A1
- Authority
- PL
- Poland
- Prior art keywords
- enantiomer
- chem
- pharmaceutically
- compound
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Luminescent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20649880A | 1980-11-14 | 1980-11-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL233786A1 true PL233786A1 (es) | 1982-05-24 |
Family
ID=22766667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL23378681A PL233786A1 (es) | 1980-11-14 | 1981-11-12 |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP0052492B1 (es) |
JP (3) | JPS57114555A (es) |
KR (1) | KR830007508A (es) |
AT (1) | ATE6422T1 (es) |
AU (1) | AU540707B2 (es) |
CA (1) | CA1181430A (es) |
CS (1) | CS227019B2 (es) |
CY (1) | CY1350A (es) |
DD (1) | DD201139A5 (es) |
DE (1) | DE3162445D1 (es) |
DK (1) | DK161887C (es) |
EG (1) | EG15458A (es) |
ES (1) | ES8206440A1 (es) |
FI (1) | FI77018C (es) |
GB (1) | GB2087883A (es) |
GR (1) | GR75395B (es) |
HK (1) | HK16087A (es) |
HU (1) | HU185475B (es) |
IE (1) | IE52170B1 (es) |
IL (1) | IL64288A (es) |
MY (1) | MY8700709A (es) |
NZ (1) | NZ198953A (es) |
PH (1) | PH17424A (es) |
PL (1) | PL233786A1 (es) |
PT (1) | PT73982B (es) |
RO (1) | RO83309B (es) |
SU (1) | SU1068034A3 (es) |
ZA (1) | ZA817863B (es) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4777291A (en) * | 1985-02-27 | 1988-10-11 | Eli Lilly And Company | Racemization process |
US4797286A (en) * | 1985-11-12 | 1989-01-10 | Eli Lilly And Company | Orally administerable sustained release pharmaceutical formulations |
US5112619A (en) * | 1985-11-12 | 1992-05-12 | Eli Lilly And Company | Orally administerable sustained release pharmaceutical formulation |
GB8823405D0 (en) * | 1988-10-05 | 1988-11-09 | Erba Carlo Spa | Aryloxy-arythio-heteraryloxy-heteroarylthio-alkenylene derivatives of amines |
DK258389D0 (da) * | 1989-05-26 | 1989-05-26 | Ferrosan As | Aryloxyphenylpropylaminer, deres fremstilling og anvendelse |
CA2061665C (en) * | 1991-02-25 | 2002-04-16 | Mark Mortensen Foreman | Treatment of lower urinary tract disorders |
EP0591434A4 (en) * | 1991-06-26 | 1994-09-14 | Sepracor Inc | Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron |
EP0612242B1 (en) * | 1991-11-15 | 2003-07-09 | Sepracor Inc. | Use of the pure s(+) isomer of fluoxetine for the preparation of a medicament against migraine headache |
CA2124445A1 (en) * | 1991-11-26 | 1993-06-10 | James W. Young | Methods and compositions for treating hypertension, angina and other disorders using optically pure (-) amlodipine |
EP0576766A1 (en) * | 1992-06-29 | 1994-01-05 | Novo Nordisk A/S | Propanolamine derivatives, their preparation and use |
TW344661B (en) * | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
WO2000051582A2 (en) | 1999-03-01 | 2000-09-08 | Sepracor Inc. | Methods for treating apnea and apnea disorders using optically pure r(+)ondansetron |
AU3219800A (en) * | 1999-03-29 | 2000-10-16 | Eli Lilly And Company | Stereospecific method for preparing tomoxetine and intermediates thereof |
EP1171417B1 (en) | 1999-04-09 | 2005-11-09 | Eli Lilly And Company | Methods for preparing 3-aryloxy-3-arylpropylamines and intermediates thereof |
DE29923134U1 (de) * | 1999-11-16 | 2000-06-29 | Schwarz Pharma Ag, 40789 Monheim | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
EP2316468A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
GB0229583D0 (en) | 2002-12-19 | 2003-01-22 | Cipla Ltd | A process for preparing duloxetine and intermediates for use therein |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
US8545881B2 (en) | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
US7439399B2 (en) * | 2004-06-28 | 2008-10-21 | Teva Pharmaceutical Fine Chemicals | Processes for the preparation of atomoxetine hydrochloride |
EP1687254A2 (en) * | 2004-06-28 | 2006-08-09 | Teva Pharmaceutical Fine Chemicals S.R.L. | Process for the optical resolution and recycling of tomoxetine |
EP1768949A2 (en) | 2004-07-22 | 2007-04-04 | Teva Pharmaceutical Fine Chemicals S.R.L. | Polymorphs of atomoxetiene hydrochloride |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
MX2007004741A (es) | 2004-10-21 | 2007-09-07 | Eurand Pharmaceuticals Ltd | Composiciones farmaceuticas con sabor enmascarado con formadores de poro gastrosolubles. |
JP2008501721A (ja) * | 2005-04-05 | 2008-01-24 | テバ ファーマシューティカル ファイン ケミカルズ ソチエタ レスポンサビリタ リミテ | 安定性アトモキセチン塩酸塩、その調製方法及びその安定性の分析的調節 |
EP1889828A1 (en) * | 2005-04-05 | 2008-02-20 | Teva Pharmaceutical Fine Chemicals S.R.L. | Stable atomoxetine hydrochloride, a process for the preparation thereof, and an analytical control of its stability |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
US7485754B2 (en) | 2005-07-08 | 2009-02-03 | Apotex Pharmachem Inc. | Efficient method for preparing 3-aryloxy-3-arylpropylamines and their optical stereoisomers |
CZ296345B6 (cs) * | 2005-07-21 | 2006-02-15 | Zentiva, A. S | Zpusob výroby hydrochloridu (R)-N-methyl-3-(2-methylfenoxy)-3-fenylpropylaminu (atomoxetinu) |
EP1798215A1 (en) * | 2005-12-14 | 2007-06-20 | SOLMAG S.p.A. | Polymorph of atomoxetine hydrochloride in crystalline form |
ITMI20061987A1 (it) * | 2006-10-16 | 2008-04-17 | Archimica Srl | Processo per la sintesi di arilossipropilammine ed eteroarilossipropilammine. |
WO2008062473A1 (en) * | 2006-10-31 | 2008-05-29 | Cadila Healthcare Limited | Process for preparing atomoxetine hydrochloride |
CN100430370C (zh) * | 2006-11-03 | 2008-11-05 | 华东理工大学 | 一种丙胺衍生物及其在制备托莫西汀中的应用 |
WO2009141833A2 (en) * | 2008-04-17 | 2009-11-26 | Ind-Swift Laboratories Limited | An improved process for synthesizing highly pure atomoxetine |
TWI471146B (zh) | 2009-12-02 | 2015-02-01 | Aptalis Pharma Ltd | 菲索特芬那定(fexofenadine)微膠囊及包含其之組合物 |
JP5973073B2 (ja) | 2013-11-08 | 2016-08-23 | イーライ リリー アンド カンパニー | アトモキセチン溶液 |
GR1008531B (el) | 2014-03-21 | 2015-07-13 | Λαμδα Φαρμακευτικα Εργαστηρια Εφαμροσμενης Ερευνας Και Αναπτυξης Α.Ε., | Ποσιμα διαλυματα που περιεχουν υδροχλωρικη ατομοξετινη |
EP3069715A1 (en) | 2015-03-20 | 2016-09-21 | Salmon Pharma GmbH | Immediate release dosage forms of Atomoxetine |
CN106916074A (zh) * | 2017-02-14 | 2017-07-04 | 万特制药(海南)有限公司 | 盐酸托莫西汀的制备 |
CN110294680A (zh) * | 2018-03-22 | 2019-10-01 | 北京深蓝海生物医药科技有限公司 | 一种盐酸阿托莫西汀的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4018895A (en) * | 1974-01-10 | 1977-04-19 | Eli Lilly And Company | Aryloxyphenylpropylamines in treating depression |
US4194009A (en) * | 1974-01-10 | 1980-03-18 | Eli Lilly And Company | Aryloxyphenylpropylamines for obtaining a psychotropic effect |
JPS5283811A (en) * | 1976-01-01 | 1977-07-13 | Lilly Co Eli | Aryloxy phenyl propylamines and their salts |
GB1596033A (en) * | 1978-04-25 | 1981-08-19 | Boots Co Ltd | (-)-(2-methoxyphenyl) ethylamine |
JPS5536403A (en) * | 1978-07-28 | 1980-03-14 | Nippon Iyakuhin Kogyo Kk | Preparation of 1-benzazonine derivative |
IT1113029B (it) * | 1979-03-01 | 1986-01-20 | Simes | Processo per la separazione dei due isomeri ottici del moprololo e composizioni farmaceutiche dell'antipodo levogiro |
-
1981
- 1981-11-12 FI FI813589A patent/FI77018C/fi not_active IP Right Cessation
- 1981-11-12 PT PT73982A patent/PT73982B/pt not_active IP Right Cessation
- 1981-11-12 PL PL23378681A patent/PL233786A1/xx unknown
- 1981-11-12 NZ NZ198953A patent/NZ198953A/en unknown
- 1981-11-12 CA CA000389954A patent/CA1181430A/en not_active Expired
- 1981-11-12 ZA ZA817863A patent/ZA817863B/xx unknown
- 1981-11-12 AU AU77427/81A patent/AU540707B2/en not_active Ceased
- 1981-11-12 RO RO105785A patent/RO83309B/ro unknown
- 1981-11-12 GR GR66518A patent/GR75395B/el unknown
- 1981-11-13 HU HU813411A patent/HU185475B/hu not_active IP Right Cessation
- 1981-11-13 AT AT81305387T patent/ATE6422T1/de not_active IP Right Cessation
- 1981-11-13 ES ES507142A patent/ES8206440A1/es not_active Expired
- 1981-11-13 CY CY135081A patent/CY1350A/xx unknown
- 1981-11-13 DE DE8181305387T patent/DE3162445D1/de not_active Expired
- 1981-11-13 DD DD81234837A patent/DD201139A5/de not_active IP Right Cessation
- 1981-11-13 PH PH26491A patent/PH17424A/en unknown
- 1981-11-13 EP EP81305387A patent/EP0052492B1/en not_active Expired
- 1981-11-13 JP JP56182953A patent/JPS57114555A/ja active Granted
- 1981-11-13 SU SU813355735A patent/SU1068034A3/ru active
- 1981-11-13 DK DK502781A patent/DK161887C/da active
- 1981-11-13 CS CS818359A patent/CS227019B2/cs unknown
- 1981-11-13 IE IE2661/81A patent/IE52170B1/en not_active IP Right Cessation
- 1981-11-13 GB GB8134282A patent/GB2087883A/en active Pending
- 1981-11-14 EG EG662/81A patent/EG15458A/xx active
- 1981-11-14 KR KR1019810004404A patent/KR830007508A/ko unknown
- 1981-11-15 IL IL64288A patent/IL64288A/xx not_active IP Right Cessation
-
1987
- 1987-02-19 HK HK160/87A patent/HK16087A/xx not_active IP Right Cessation
- 1987-12-30 MY MY709/87A patent/MY8700709A/xx unknown
-
1990
- 1990-06-05 JP JP2147166A patent/JPH037250A/ja active Granted
- 1990-06-05 JP JP2147167A patent/JPH037251A/ja active Granted
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