PL1802291T3 - Oparte na kaliksarenie mimetyki konformacji peptydu, sposoby ich stosowania oraz sposoby przygotowania - Google Patents
Oparte na kaliksarenie mimetyki konformacji peptydu, sposoby ich stosowania oraz sposoby przygotowaniaInfo
- Publication number
- PL1802291T3 PL1802291T3 PL05817221T PL05817221T PL1802291T3 PL 1802291 T3 PL1802291 T3 PL 1802291T3 PL 05817221 T PL05817221 T PL 05817221T PL 05817221 T PL05817221 T PL 05817221T PL 1802291 T3 PL1802291 T3 PL 1802291T3
- Authority
- PL
- Poland
- Prior art keywords
- methods
- calixarene
- based peptide
- mimetics
- making
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/08—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61613304P | 2004-10-04 | 2004-10-04 | |
EP05817221A EP1802291B1 (en) | 2004-10-04 | 2005-10-04 | Calixarene-based peptide conformation mimetics, methods of use, and methods of making |
PCT/US2005/036128 WO2006042104A2 (en) | 2004-10-04 | 2005-10-04 | Calixarene-based peptide conformation mimetics, methods of use, and methods of making |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1802291T3 true PL1802291T3 (pl) | 2012-05-31 |
Family
ID=36011008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL05817221T PL1802291T3 (pl) | 2004-10-04 | 2005-10-04 | Oparte na kaliksarenie mimetyki konformacji peptydu, sposoby ich stosowania oraz sposoby przygotowania |
Country Status (9)
Country | Link |
---|---|
US (3) | US8207228B2 (pl) |
EP (2) | EP1802291B1 (pl) |
AT (1) | ATE536177T1 (pl) |
CA (2) | CA2867023A1 (pl) |
DK (1) | DK1802291T3 (pl) |
ES (1) | ES2378999T3 (pl) |
PL (1) | PL1802291T3 (pl) |
PT (1) | PT1802291E (pl) |
WO (1) | WO2006042104A2 (pl) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1372674B1 (en) | 2001-03-08 | 2011-05-25 | The Trustees of The University of Pennsylvania | Facially amphiphilic polymers as anti-infective agents |
EP1572719A4 (en) | 2002-02-20 | 2007-11-14 | Univ Minnesota | PARTIAL PEPTIDE MIMETICS AND METHOD |
KR101241176B1 (ko) | 2003-03-17 | 2013-03-13 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 표면적으로 양쪽성인 중합체 및 올리고머 및 이의 용도 |
TWI388280B (zh) | 2004-01-23 | 2013-03-11 | Univ Pennsylvania | 面上兩性之聚芳基和聚芳炔基聚合物與寡聚物及其用途 |
WO2006042104A2 (en) | 2004-10-04 | 2006-04-20 | Regents Of The University Of Minnesota | Calixarene-based peptide conformation mimetics, methods of use, and methods of making |
GB0606947D0 (en) * | 2006-04-05 | 2006-05-17 | Univ Bath | Reagents and methods for cross-linking biological molecules |
WO2012061395A2 (en) | 2010-11-01 | 2012-05-10 | Regents Of The University Of Minnesota | Cytotoxic agents against cancer cells and uses thereof |
JPWO2012133040A1 (ja) * | 2011-03-28 | 2014-07-28 | 株式会社トクヤマ | カリックスアレーン誘導体 |
WO2012131079A1 (en) | 2011-03-30 | 2012-10-04 | Oncoethix | Compounds inhibiting galectin-1 expression, cancer cell proliferation, invasion, and tumorigenesis |
FR2974013B1 (fr) * | 2011-04-12 | 2017-02-17 | Univ De Nancy 1 Henri Poincare | Utilisation de calixarenes associes avec un antibiotique dans le traitement des infections bacteriennes |
FR2974012A1 (fr) * | 2011-04-12 | 2012-10-19 | Univ Nancy 1 Henri Poincare | Utilisation de calixarenes dans le traitement des infections bacteriennes |
ITMI20111532A1 (it) | 2011-08-11 | 2013-02-12 | Univ Parma | Derivati calixarenici funzionalizzati per la transfezione cellulare |
RU2480451C1 (ru) * | 2012-03-21 | 2013-04-27 | Федеральное государственное бюджетное учреждение науки Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра Российской академии наук | Производное тетраметилоксифенилкаликс[4]арена для сорбции азо-красителей из водных растворов |
CN104540528B (zh) * | 2012-06-11 | 2018-07-03 | 皇家飞利浦有限公司 | 化合物0118的放射性标记类似物及其用途 |
AU2013315019B2 (en) | 2012-09-17 | 2017-06-01 | Galectin Therapeutics, Inc. | Method for enhancing specific immunotherapies in cancer treatment |
KR20160040466A (ko) * | 2013-05-22 | 2016-04-14 | 알렉스 필립 그레이엄 로빈손 | 풀러렌 |
JP6494444B2 (ja) * | 2014-07-08 | 2019-04-03 | 昭和電工株式会社 | ポリアルケニルフェノール化合物の製造方法 |
US20200277378A1 (en) | 2017-11-16 | 2020-09-03 | Novartis Ag | Combination therapies |
JP2021529163A (ja) | 2018-06-29 | 2021-10-28 | グリコス バイオメディカル オーワイ | コンジュゲート |
AR116109A1 (es) | 2018-07-10 | 2021-03-31 | Novartis Ag | Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos |
CN113271945A (zh) | 2018-12-20 | 2021-08-17 | 诺华股份有限公司 | 包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案和药物组合 |
WO2020165833A1 (en) | 2019-02-15 | 2020-08-20 | Novartis Ag | 3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof |
JP2022520448A (ja) | 2019-02-15 | 2022-03-30 | ノバルティス アーゲー | 置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用 |
US20230038373A1 (en) | 2019-12-18 | 2023-02-09 | Glykos Biomedical Oy | Stabile conjugate |
CA3165399A1 (en) | 2019-12-20 | 2021-06-24 | Novartis Ag | Uses of anti-tgf-beta antibodies and checkpoint inhibitors for the treatment of proliferative diseases |
US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
IL298262A (en) | 2020-06-23 | 2023-01-01 | Novartis Ag | A dosage regimen that includes derivatives of 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione |
EP4188549A1 (en) | 2020-08-03 | 2023-06-07 | Novartis AG | Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof |
TW202304979A (zh) | 2021-04-07 | 2023-02-01 | 瑞士商諾華公司 | 抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途 |
AR125874A1 (es) | 2021-05-18 | 2023-08-23 | Novartis Ag | Terapias de combinación |
CN114652849B (zh) * | 2022-03-22 | 2023-11-17 | 南开大学 | 可同时递送多种药物并精确调控药物比例的杯芳烃修饰白蛋白的制备方法和应用 |
Family Cites Families (22)
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US5409959A (en) * | 1991-01-29 | 1995-04-25 | Genelabs Incorporated | Antithrombotic treatment with calix(n)arene compounds |
US5312837A (en) * | 1991-01-29 | 1994-05-17 | Genelabs Technologies, Inc. | Method of treating viral infections with aryl macrocyclic compounds |
US5489612A (en) | 1991-08-23 | 1996-02-06 | The University Of Alabama At Birmingham Research Foundation | Calixarene chloride-channel blockers |
WO1995019974A2 (en) * | 1994-01-24 | 1995-07-27 | Harris Stephen J | Calixarene-based compounds having antibacterial, antifungal, anticancer-hiv activity |
US5786324A (en) * | 1994-03-24 | 1998-07-28 | Regents Of The University Of Minnesota | Synthetic peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use |
US5830860A (en) * | 1994-03-24 | 1998-11-03 | Regents Of The University Of Minnesota | Peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use |
WO1997044354A2 (en) * | 1996-05-24 | 1997-11-27 | Regents Of The University Of Minnesota | Synthesis of soluble beta-sheet forming peptides |
US5955577A (en) * | 1996-06-27 | 1999-09-21 | Regents Of The University Of Minnesota | Method for synthesizing a water-soluble β-sheet forming peptide |
IL127956A0 (en) * | 1996-07-11 | 1999-11-30 | Farmarc Nederland Bv | Inclusion complex containing indole selective serotonin agonist |
GB9713292D0 (en) * | 1997-06-25 | 1997-08-27 | Secr Defence | Novel cation receptor |
WO1999035667A1 (en) * | 1998-01-09 | 1999-07-15 | E.I. Du Pont De Nemours And Company | Plasma treatment for producing electron emitters |
CA2397835A1 (en) * | 2000-01-20 | 2001-07-26 | Regents Of The University Of Minnesota | Polypeptides with therapeutic activity and methods of use |
US20030207890A1 (en) * | 2001-02-23 | 2003-11-06 | Collier Robert J | Compounds with 5-ht1a activity useful for treating disorders of the outer retina |
AU2001245888A1 (en) | 2000-03-21 | 2001-10-03 | University Of South Florida | Growth factor binding molecules |
EP1572719A4 (en) * | 2002-02-20 | 2007-11-14 | Univ Minnesota | PARTIAL PEPTIDE MIMETICS AND METHOD |
CA2541856A1 (en) * | 2003-10-17 | 2005-05-12 | Regents Of The University Of Minnesota | Modified polypeptides with therapeutic activity and methods of use |
US7482483B2 (en) | 2004-01-27 | 2009-01-27 | University Of South Florida | Growth factor-binding compounds and methods of use |
US20050266575A1 (en) * | 2004-05-27 | 2005-12-01 | Mayo Kevin H | Pharmacophores for nociceptin, methods of obtaining and using in screening for nociceptin mimics |
CN1997622B (zh) | 2004-06-15 | 2012-08-22 | 宝利麦迪克斯股份有限公司 | 聚阳离子化合物及其用途 |
WO2006010138A1 (en) | 2004-07-08 | 2006-01-26 | Regents Of The University Of Minnesota | Bioactive chemokine heteromultimers |
WO2006042104A2 (en) | 2004-10-04 | 2006-04-20 | Regents Of The University Of Minnesota | Calixarene-based peptide conformation mimetics, methods of use, and methods of making |
US20070010438A1 (en) * | 2005-07-08 | 2007-01-11 | Mayo Kevin H | Tumor treatment using beta-sheet peptides and radiotherapy |
-
2005
- 2005-10-04 WO PCT/US2005/036128 patent/WO2006042104A2/en active Application Filing
- 2005-10-04 EP EP05817221A patent/EP1802291B1/en not_active Not-in-force
- 2005-10-04 US US11/664,641 patent/US8207228B2/en active Active
- 2005-10-04 PL PL05817221T patent/PL1802291T3/pl unknown
- 2005-10-04 AT AT05817221T patent/ATE536177T1/de active
- 2005-10-04 CA CA2867023A patent/CA2867023A1/en not_active Abandoned
- 2005-10-04 DK DK05817221.4T patent/DK1802291T3/da active
- 2005-10-04 CA CA2583092A patent/CA2583092C/en not_active Expired - Fee Related
- 2005-10-04 ES ES05817221T patent/ES2378999T3/es active Active
- 2005-10-04 EP EP11173181A patent/EP2404895A1/en not_active Withdrawn
- 2005-10-04 PT PT05817221T patent/PT1802291E/pt unknown
-
2012
- 2012-04-24 US US13/454,525 patent/US8716343B2/en not_active Expired - Fee Related
- 2012-09-28 US US13/630,394 patent/US8642656B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2867023A1 (en) | 2006-04-20 |
EP1802291B1 (en) | 2011-12-07 |
WO2006042104A3 (en) | 2007-01-18 |
US20080300164A1 (en) | 2008-12-04 |
US8642656B2 (en) | 2014-02-04 |
CA2583092C (en) | 2014-12-30 |
ATE536177T1 (de) | 2011-12-15 |
US8716343B2 (en) | 2014-05-06 |
US8207228B2 (en) | 2012-06-26 |
ES2378999T3 (es) | 2012-04-19 |
US20130035394A1 (en) | 2013-02-07 |
WO2006042104A2 (en) | 2006-04-20 |
PT1802291E (pt) | 2012-03-12 |
EP1802291A2 (en) | 2007-07-04 |
CA2583092A1 (en) | 2006-04-20 |
DK1802291T3 (da) | 2012-03-26 |
EP2404895A1 (en) | 2012-01-11 |
US20120309801A1 (en) | 2012-12-06 |
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