PL1606277T3 - Pochodne imidazol-4-iloetynylo-pirydyny - Google Patents
Pochodne imidazol-4-iloetynylo-pirydynyInfo
- Publication number
- PL1606277T3 PL1606277T3 PL04717578T PL04717578T PL1606277T3 PL 1606277 T3 PL1606277 T3 PL 1606277T3 PL 04717578 T PL04717578 T PL 04717578T PL 04717578 T PL04717578 T PL 04717578T PL 1606277 T3 PL1606277 T3 PL 1606277T3
- Authority
- PL
- Poland
- Prior art keywords
- imidazol
- ethynyl
- pyridine derivatives
- pyridine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03004952 | 2003-03-10 | ||
PCT/EP2004/002276 WO2004080998A1 (en) | 2003-03-10 | 2004-03-05 | Imidazol-4-yl-ethynyl-pyridine derivatives |
EP04717578A EP1606277B8 (en) | 2003-03-10 | 2004-03-05 | Imidazol-4-yl-ethynyl-pyridine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1606277T3 true PL1606277T3 (pl) | 2008-10-31 |
Family
ID=32981724
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL04717578T PL1606277T3 (pl) | 2003-03-10 | 2004-03-05 | Pochodne imidazol-4-iloetynylo-pirydyny |
Country Status (31)
Country | Link |
---|---|
US (1) | US7153874B2 (pl) |
EP (1) | EP1606277B8 (pl) |
JP (1) | JP4404896B2 (pl) |
KR (1) | KR100742019B1 (pl) |
CN (1) | CN100358889C (pl) |
AR (1) | AR043501A1 (pl) |
AT (1) | ATE395345T1 (pl) |
AU (1) | AU2004220382B2 (pl) |
BR (1) | BRPI0408093A (pl) |
CA (1) | CA2516682C (pl) |
CL (1) | CL2004000449A1 (pl) |
CO (1) | CO5601027A2 (pl) |
DE (1) | DE602004013746D1 (pl) |
DK (1) | DK1606277T3 (pl) |
ES (1) | ES2305739T3 (pl) |
HK (1) | HK1089443A1 (pl) |
HR (1) | HRP20050774A2 (pl) |
IL (1) | IL170129A (pl) |
MX (1) | MXPA05009524A (pl) |
MY (1) | MY135491A (pl) |
NO (1) | NO20054136L (pl) |
NZ (1) | NZ541643A (pl) |
PA (1) | PA8597301A1 (pl) |
PE (1) | PE20041061A1 (pl) |
PL (1) | PL1606277T3 (pl) |
PT (1) | PT1606277E (pl) |
RU (1) | RU2342383C2 (pl) |
SI (1) | SI1606277T1 (pl) |
TW (1) | TWI292318B (pl) |
WO (1) | WO2004080998A1 (pl) |
ZA (1) | ZA200506834B (pl) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA80888C2 (en) * | 2003-06-05 | 2007-11-12 | Hoffmann La Roche | Imidazole derivatives as glutmate receptor antagonists |
US7452909B2 (en) * | 2003-09-04 | 2008-11-18 | Hoffman-La Roche Inc. | Imidazole derivatives |
JP4690395B2 (ja) | 2004-06-01 | 2011-06-01 | エフ.ホフマン−ラ ロシュ アーゲー | mGlu5レセプターアンタゴニストとしてのピリジン−4−エチニル−イミダゾール及びピラゾール |
DE602005007350D1 (de) * | 2004-06-01 | 2008-07-17 | Hoffmann La Roche | Pyridin-4-yl-ethynylimidazole und -pyrazole als antagonisten des mglu5-rezeptors |
WO2007025177A2 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
EP2377530A3 (en) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
DE102006011574A1 (de) | 2006-03-10 | 2007-10-31 | Grünenthal GmbH | Substituierte Imidazo[2,1-b]thiazol-Verbindungen und ihre Verwendung zur Herstellung von Arzneimitteln |
EP2377531A2 (en) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
MX2009002496A (es) * | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
BRPI0720954A2 (pt) | 2006-12-21 | 2014-03-18 | Hoffmann La Roche | Polimorfos de um antagonista de receptor mglur5 |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
US8334287B2 (en) * | 2009-07-17 | 2012-12-18 | Hoffmann-La Roche Inc. | Imidazoles |
US8586581B2 (en) * | 2009-12-17 | 2013-11-19 | Hoffmann-La Roche Inc | Ethynyl compounds useful for treatment of CNS disorders |
DK2702051T3 (en) | 2011-04-26 | 2015-03-16 | Hoffmann La Roche | Ethynyl derivatives AS POSITIVE allosteric modulators mGluR5 |
UA116023C2 (uk) | 2013-07-08 | 2018-01-25 | Ф. Хоффманн-Ля Рош Аг | Етинільні похідні як антагоністи метаботропного глутаматного рецептора |
WO2017117708A1 (en) * | 2016-01-05 | 2017-07-13 | Hua Medicine (Shanghai) Ltd. | Pyrazole derivatives |
CN110382485B (zh) | 2017-01-10 | 2022-05-10 | 拜耳公司 | 作为害虫防治剂的杂环烯衍生物 |
AR113206A1 (es) | 2017-01-10 | 2020-02-19 | Bayer Cropscience Ag | Derivados heterocíclicos como pesticidas |
JP2023504177A (ja) * | 2019-12-02 | 2023-02-01 | エフ.ホフマン-ラ ロシュ アーゲー | アルキニル-(ヘテロアリール)-カルボキサミドhcn1阻害剤 |
CN111416154B (zh) * | 2020-05-22 | 2021-08-06 | 松山湖材料实验室 | 高电压锂离子电池电解液硅基吡啶添加剂、电解液及其电池 |
BR112023019532A2 (pt) | 2021-03-27 | 2023-10-31 | Syngenta Crop Protection Ag | Derivados de amida isonicotínicos microbicidas |
WO2023089049A2 (en) | 2021-11-19 | 2023-05-25 | Syngenta Crop Protection Ag | Microbiocidal isonicotinic amide derivatives |
WO2024132901A1 (en) | 2022-12-19 | 2024-06-27 | Syngenta Crop Protection Ag | Microbiocidal pyridazine dihydrooxadiazine derivatives |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3303199A (en) | 1963-07-15 | 1967-02-07 | Geigy Chem Corp | Certain imidazolone derivatives and process for making same |
US3341548A (en) | 1964-04-29 | 1967-09-12 | Hoffmann La Roche | Nitroimidazoles and their preparation |
DE2035905A1 (de) | 1970-07-20 | 1972-02-03 | Chemische Fabrik Stockhausen & Cie.,4150Krefeld | Imidazolverbindungen und deren Herstellungsverfahren |
CA1174673A (en) | 1981-02-27 | 1984-09-18 | Walter Hunkeler | Imidazodiazepines |
US4711962A (en) | 1984-10-18 | 1987-12-08 | Stauffer Chemical Company | Process for selective preparation of ratios of isomers formed on N-substitution of asymmetric imidazoles |
US4882343A (en) * | 1987-08-28 | 1989-11-21 | G. D. Searle & Co. | Biarylalkylimidazole derivatives as anti-depressants |
ATE134368T1 (de) | 1989-06-30 | 1996-03-15 | Du Pont | Substituierte imidazole und ihre verwendung als hemmmstoff fur angiotensin ii |
TW544448B (en) | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
CN1154489C (zh) | 1997-08-14 | 2004-06-23 | 弗·哈夫曼-拉罗切有限公司 | 抗神经学疾病的杂环乙烯基醚 |
JP4815083B2 (ja) | 1999-08-31 | 2011-11-16 | メルク・シャープ・エンド・ドーム・コーポレイション | 複素環化合物およびそれの使用方法 |
CA2430696C (en) | 2000-12-04 | 2009-01-27 | F. Hoffmann-La Roche Ag | Phenylethenyl or phenylethinyl derivatives as glutamate receptor antagonists |
CA2470612A1 (en) * | 2001-12-19 | 2003-07-03 | Merck & Co., Inc. | Heteroaryl substituted imidazole modulators of metabotropic glutamate receptor-5 |
-
2004
- 2004-03-04 TW TW093105737A patent/TWI292318B/zh not_active IP Right Cessation
- 2004-03-05 WO PCT/EP2004/002276 patent/WO2004080998A1/en active IP Right Grant
- 2004-03-05 AT AT04717578T patent/ATE395345T1/de active
- 2004-03-05 SI SI200430735T patent/SI1606277T1/sl unknown
- 2004-03-05 DK DK04717578T patent/DK1606277T3/da active
- 2004-03-05 PA PA20048597301A patent/PA8597301A1/es unknown
- 2004-03-05 JP JP2006504558A patent/JP4404896B2/ja not_active Expired - Fee Related
- 2004-03-05 PT PT04717578T patent/PT1606277E/pt unknown
- 2004-03-05 BR BRPI0408093-9A patent/BRPI0408093A/pt not_active IP Right Cessation
- 2004-03-05 EP EP04717578A patent/EP1606277B8/en not_active Expired - Lifetime
- 2004-03-05 CA CA002516682A patent/CA2516682C/en not_active Expired - Fee Related
- 2004-03-05 RU RU2005131165/04A patent/RU2342383C2/ru not_active IP Right Cessation
- 2004-03-05 PL PL04717578T patent/PL1606277T3/pl unknown
- 2004-03-05 ES ES04717578T patent/ES2305739T3/es not_active Expired - Lifetime
- 2004-03-05 KR KR1020057016753A patent/KR100742019B1/ko not_active IP Right Cessation
- 2004-03-05 NZ NZ541643A patent/NZ541643A/en unknown
- 2004-03-05 AU AU2004220382A patent/AU2004220382B2/en not_active Ceased
- 2004-03-05 DE DE602004013746T patent/DE602004013746D1/de not_active Expired - Lifetime
- 2004-03-05 MX MXPA05009524A patent/MXPA05009524A/es active IP Right Grant
- 2004-03-05 CN CNB2004800065725A patent/CN100358889C/zh not_active Expired - Fee Related
- 2004-03-08 CL CL200400449A patent/CL2004000449A1/es unknown
- 2004-03-08 US US10/795,619 patent/US7153874B2/en not_active Expired - Fee Related
- 2004-03-08 AR ARP040100722A patent/AR043501A1/es not_active Application Discontinuation
- 2004-03-08 PE PE2004000252A patent/PE20041061A1/es not_active Application Discontinuation
- 2004-03-09 MY MYPI20040806A patent/MY135491A/en unknown
-
2005
- 2005-08-04 IL IL170129A patent/IL170129A/en not_active IP Right Cessation
- 2005-08-25 CO CO05085015A patent/CO5601027A2/es active IP Right Grant
- 2005-08-25 ZA ZA200506834A patent/ZA200506834B/en unknown
- 2005-09-05 HR HR20050774A patent/HRP20050774A2/xx not_active Application Discontinuation
- 2005-09-06 NO NO20054136A patent/NO20054136L/no not_active Application Discontinuation
-
2006
- 2006-09-06 HK HK06109889A patent/HK1089443A1/xx not_active IP Right Cessation
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