PH16138A - Process for the preparation of 6-alpha-halo-substituted-pregna-4-ene-3 ones and pregna-1,4-diene-3-ones - Google Patents

Process for the preparation of 6-alpha-halo-substituted-pregna-4-ene-3 ones and pregna-1,4-diene-3-ones

Info

Publication number
PH16138A
PH16138A PH22354A PH22354A PH16138A PH 16138 A PH16138 A PH 16138A PH 22354 A PH22354 A PH 22354A PH 22354 A PH22354 A PH 22354A PH 16138 A PH16138 A PH 16138A
Authority
PH
Philippines
Prior art keywords
pregna
ones
ene
diene
halo
Prior art date
Application number
PH22354A
Other languages
English (en)
Inventor
Peter Macdonald
Original Assignee
Prochem Ets
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prochem Ets filed Critical Prochem Ets
Publication of PH16138A publication Critical patent/PH16138A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Epoxy Compounds (AREA)
PH22354A 1978-04-05 1979-04-05 Process for the preparation of 6-alpha-halo-substituted-pregna-4-ene-3 ones and pregna-1,4-diene-3-ones PH16138A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL7803656 1978-04-05
NL7803655 1978-04-05
NLAANVRAGE7902333,A NL187577C (nl) 1978-04-05 1979-03-23 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.

Publications (1)

Publication Number Publication Date
PH16138A true PH16138A (en) 1983-07-08

Family

ID=27352047

Family Applications (1)

Application Number Title Priority Date Filing Date
PH22354A PH16138A (en) 1978-04-05 1979-04-05 Process for the preparation of 6-alpha-halo-substituted-pregna-4-ene-3 ones and pregna-1,4-diene-3-ones

Country Status (9)

Country Link
US (1) US4255331A (de)
JP (1) JPS6425793A (de)
CH (1) CH639655A5 (de)
DE (1) DE2913147A1 (de)
FI (1) FI66395C (de)
FR (1) FR2421914A1 (de)
GB (1) GB2018258B (de)
NL (1) NL187577C (de)
PH (1) PH16138A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188322A (en) * 1978-04-28 1980-02-12 Blasinachim S.P.A. Process for the preparation of 6-halo-pregnanes
DE3069074D1 (en) 1979-11-16 1984-10-04 Sterosynt Ltd 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
HU182775B (en) * 1981-10-15 1984-03-28 Richter Gedeon Vegyeszet Process for preparing new 3-chloro-pregnane derivatives
FR2701262B1 (fr) * 1993-02-05 1995-03-24 Roussel Uclaf Nouveau procédé de préparation de stéroïdes 6 alpa, 9 alpha-difluorés et nouveaus intermédiaires.
GB0017988D0 (en) * 2000-07-21 2000-09-13 Glaxo Group Ltd Novel process
IT1319663B1 (it) * 2000-11-17 2003-10-23 Farmabios Srl Processo per la preparazione di fluoro-steroidi.
PT102628B (pt) * 2001-06-12 2010-09-09 Hovione Farmaciencia S A Novo processo de preparação de flumetasona e do seu análogo 17-carboxilo androsteno
EP1275656A1 (de) * 2001-07-11 2003-01-15 Genchem Pharma Limited Herstellung von 9alpha-fluoro-11beta-Hydroxypregnan-16,17-acetal-Derivaten
MXPA04005188A (es) 2001-11-29 2004-08-11 Taro Pharma Ind Metodo para la produccion de 6-alfa-fluorocorticosteroides.
MXPA05006279A (es) * 2002-12-09 2006-01-27 Sicor Inc Proceso para la preparacion de pregnanos.
CA2805832A1 (en) 2010-07-20 2012-01-26 Taro Pharmaceutical Industries Ltd. Process for the preparation of 17-desoxy-corticosteroids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU75903A1 (de) * 1976-09-29 1978-05-16
US3047596A (en) * 1959-11-17 1962-07-31 Merck & Co Inc 6alpha-halogen-9alpha-halogen-delta-pregnadiene-3-one compounds
SE339685B (de) * 1967-06-16 1971-10-18 Warner Lambert Pharmaceutical
DE2365992C3 (de) * 1972-03-09 1982-05-19 The Upjohn Co., 49001 Kalamazoo, Mich. 6α-Fluor-17,21-dihydroxy-16β-methylpregna-4,9(11)-dien-3,20-dion-17,21-diacetat und Verfahren zu dessen Herstellung
US4188322A (en) * 1978-04-28 1980-02-12 Blasinachim S.P.A. Process for the preparation of 6-halo-pregnanes

Also Published As

Publication number Publication date
NL7902333A (nl) 1979-10-09
JPH0217560B2 (de) 1990-04-20
NL187577C (nl) 1991-11-18
CH639655A5 (de) 1983-11-30
NL187577B (nl) 1991-06-17
DE2913147A1 (de) 1979-10-18
FI791124A (fi) 1979-10-06
FR2421914B1 (de) 1983-07-22
FI66395C (fi) 1984-10-10
FI66395B (fi) 1984-06-29
GB2018258A (en) 1979-10-17
DE2913147C2 (de) 1988-06-30
GB2018258B (en) 1983-02-02
JPS6425793A (en) 1989-01-27
FR2421914A1 (fr) 1979-11-02
US4255331A (en) 1981-03-10

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