PH10519A - 4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof - Google Patents

4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof

Info

Publication number: PH10519A
Authority: PH; Philippines
Prior art keywords: hydroxymethyl; pharmaceutical compositions; phthalazone derivatives; phthalazone; derivatives
Prior art date: 1973-10-30

Application number

PH16465A

Other languages

English (en)

Inventor

T Shimamoto

M Ishikawa

T Tsuchiya

M Inoue

Original Assignee

Shimamoto Takio

M Ishikawa

Tsuchiya Takashi

Inoue Michiro

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-30

Filing date

1974-10-30

Publication date

1977-05-26

1973-10-30 Priority claimed from JP12126073A external-priority patent/JPS5732065B2/ja

1973-10-31 Priority claimed from JP12175773A external-priority patent/JPS5724786B2/ja

1974-10-30 Application filed by Shimamoto Takio, M Ishikawa, Tsuchiya Takashi, Inoue Michiro filed Critical Shimamoto Takio

1977-05-26 Publication of PH10519A publication Critical patent/PH10519A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PH16465A 1973-10-30 1974-10-30 4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof PH10519A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP12126073A JPS5732065B2 (ja)	1973-10-30	1973-10-30
JP12175773A JPS5724786B2 (ja)	1973-10-31	1973-10-31

Publications (1)

Publication Number	Publication Date
PH10519A true PH10519A (en)	1977-05-26

Family

ID=26458679

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH16465A PH10519A (en)	1973-10-30	1974-10-30	4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof

Country Status (20)

Country	Link
US (1)	US3963716A (ja)
AR (1)	AR205004A1 (ja)
CA (1)	CA1029377A (ja)
CH (2)	CH611282A5 (ja)
DD (1)	DD119231A5 (ja)
DE (1)	DE2451417C3 (ja)
DK (1)	DK134345B (ja)
ES (1)	ES431454A1 (ja)
FI (1)	FI59402C (ja)
FR (1)	FR2248841B1 (ja)
GB (1)	GB1459606A (ja)
HU (1)	HU168797B (ja)
IE (1)	IE39831B1 (ja)
IL (1)	IL45675A (ja)
IN (1)	IN139552B (ja)
LU (1)	LU71191A1 (ja)
NL (1)	NL7414186A (ja)
PH (1)	PH10519A (ja)
SE (1)	SE412389B (ja)
YU (1)	YU289774A (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4120960A (en) *	1973-10-31	1978-10-17	The Boots Company Limited	Therapeutic agents
NL7702763A (nl) *	1976-03-18	1977-09-20	Takio Shimamoto En Masayuki Is	Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten.
IE47592B1 (en) *	1977-12-29	1984-05-02	Ici Ltd	Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4293553A (en) *	1978-08-11	1981-10-06	Masayuki Ishikawa	1-Phthalazone derivatives, and use thereof
US4464532A (en) *	1979-07-31	1984-08-07	Nippon Kayaku Kabushiki Kaisha	Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone
JPS5668609A (en) *	1979-11-07	1981-06-09	Nippon Kayaku Co Ltd	Phthalazinol preparation
JPS58116471A (ja) *	1981-12-29	1983-07-11	Nippon Kayaku Co Ltd	４−ヒドロキシメチル−１−フタラゾンエステル誘導体およびその塩
GB2127805A (en) *	1982-09-13	1984-04-18	Showa Denko Kk	Phthalazones
US4861778A (en) *	1986-06-16	1989-08-29	Research Corporation	2,3-dihydrophthalazine-1,4-diones
DE68920798T2 (de) *	1988-08-19	1995-05-18	Warner Lambert Co	Substituierte Dihydroisochinolinone und verwandte Verbindungen als Verstärker der letalen Effekte von Bestrahlung und bestimmten Chemotherapeutika; ausgewählte Verbindungen, Analoga und Verfahren.
US5177075A (en) *	1988-08-19	1993-01-05	Warner-Lambert Company	Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
DE4333761A1 (de) *	1993-10-04	1995-04-06	Luitpold Pharma Gmbh	Heterocyclische Carbamate, Verfahren zu ihrer Herstellung und Arzneimittel
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
EP2527360B1 (en)	2007-06-04	2015-10-28	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en)	2008-06-04	2010-05-13	Synergy Pharmaceuticals, Inc.	Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8034782B2 (en)	2008-07-16	2011-10-11	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
KR101701943B1 (ko)	2009-11-13	2017-02-02	도레이 카부시키가이샤	당뇨병의 치료 또는 예방약
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CA2828346C (en)	2011-03-01	2021-01-26	Synergy Pharmaceuticals Inc.	Process of preparing guanylate cyclase c agonists
EP3718557A3 (en)	2013-02-25	2020-10-21	Bausch Health Ireland Limited	Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing
EP2970384A1 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
CA2905435A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
EA201592263A1 (ru)	2013-06-05	2016-05-31	Синерджи Фармасьютикалз, Инк.	Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
CA2920856A1 (en)	2013-08-09	2015-02-12	Ardelyx, Inc.	Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
JP2022533251A (ja)	2019-05-21	2022-07-21	アルデリックス，インコーポレイテッド	患者において血清リン酸塩を低下させるための組み合わせ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5116430B2 (ja) *	1971-08-05	1976-05-24
US3870792A (en) *	1972-07-24	1975-03-11	Michiro Inoue	Certain dihydrophthalizines for treating hemorrhage and thrombosis

1974
- 1974-01-01 AR AR256326A patent/AR205004A1/es active
- 1974-09-03 IE IE1825/74A patent/IE39831B1/en unknown
- 1974-09-04 GB GB3870874A patent/GB1459606A/en not_active Expired
- 1974-09-10 US US05/504,745 patent/US3963716A/en not_active Expired - Lifetime
- 1974-09-16 IL IL45675A patent/IL45675A/xx unknown
- 1974-10-23 FR FR7435550A patent/FR2248841B1/fr not_active Expired
- 1974-10-24 CA CA212,163A patent/CA1029377A/en not_active Expired
- 1974-10-28 SE SE7413530A patent/SE412389B/xx not_active IP Right Cessation
- 1974-10-28 DK DK561874AA patent/DK134345B/da not_active IP Right Cessation
- 1974-10-28 LU LU71191A patent/LU71191A1/xx unknown
- 1974-10-29 DE DE2451417A patent/DE2451417C3/de not_active Expired
- 1974-10-29 HU HUIO218A patent/HU168797B/hu unknown
- 1974-10-29 YU YU02897/74A patent/YU289774A/xx unknown
- 1974-10-29 ES ES431454A patent/ES431454A1/es not_active Expired
- 1974-10-29 FI FI3157/74A patent/FI59402C/fi active
- 1974-10-30 NL NL7414186A patent/NL7414186A/xx not_active Application Discontinuation
- 1974-10-30 DD DD182046A patent/DD119231A5/xx unknown
- 1974-10-30 CH CH497878A patent/CH611282A5/xx not_active IP Right Cessation
- 1974-10-30 PH PH16465A patent/PH10519A/en unknown
- 1974-10-30 CH CH1454674A patent/CH610892A5/xx not_active IP Right Cessation
1976
- 1976-02-25 IN IN330/CAL/76A patent/IN139552B/en unknown

Also Published As

Publication number	Publication date
IL45675A0 (en)	1974-11-29
IL45675A (en)	1978-10-31
SE7413530L (ja)	1975-05-02
FI59402C (fi)	1981-08-10
CA1029377A (en)	1978-04-11
FI315774A (ja)	1975-05-01
CH611282A5 (ja)	1979-05-31
DE2451417C3 (de)	1981-01-29
DE2451417A1 (de)	1975-05-07
NL7414186A (nl)	1975-05-02
SE412389B (sv)	1980-03-03
GB1459606A (en)	1976-12-22
FR2248841B1 (ja)	1978-07-28
YU289774A (en)	1983-01-21
DK561874A (ja)	1975-07-07
IE39831L (en)	1975-04-30
US3963716A (en)	1976-06-15
AU7295474A (en)	1976-03-11
AR205004A1 (es)	1976-03-31
IN139552B (ja)	1976-07-03
LU71191A1 (ja)	1975-04-17
DK134345B (da)	1976-10-25
FI59402B (fi)	1981-04-30
FR2248841A1 (ja)	1975-05-23
ES431454A1 (es)	1976-10-16
DD119231A5 (ja)	1976-04-12
DK134345C (ja)	1977-03-21
IE39831B1 (en)	1979-01-03
HU168797B (ja)	1976-07-28
CH610892A5 (ja)	1979-05-15
DE2451417B2 (de)	1980-05-14

Publication	Publication Date	Title
PH10519A (en)	1977-05-26	4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof
ZA743934B (en)	1975-06-25	Pharmaceutical compositions
PH10649A (en)	1977-07-27	Sulphoxide derivatives and pharmaceutical compositions thereof
IL43853A0 (en)	1974-03-14	Pharmaceutical compositions and their manufacture
IL44795A0 (en)	1974-07-31	Pharmaceutical compositions containing arylthioalkanols and novel arylthioalkanols
IL46050A0 (en)	1975-02-10	Azepinoquinoline derivatives,their preparation and pharmaceutical compositions containing them
GB1482552A (en)	1977-08-10	Benzomorphanes and morphinane derivatives and pharmaceutical compositions containing the same
PH12944A (en)	1979-10-18	Pyrazole derivatives and their pharmaceutical composition
IL44427A0 (en)	1974-06-30	Dibenzothiepine derivatives,their manufacture and pharmaceutical compositions containing them
HK72578A (en)	1978-12-15	Pharmaceutical compositions
IL46183A (en)	1978-10-31	3-aminoalkylamino-1-phenoxy-2propanol derivatives,their preparation and pharmaceutical compositions comprising them
ZA744373B (en)	1975-07-30	Pharmaceutical compositions
PH11400A (en)	1977-12-14	Naphthyridine derivatives and pharmaceutical composition thereof
PH10643A (en)	1977-07-22	Benzylpyrimidine derivatives and pharmaceutical compositions thereof
ZA742956B (en)	1975-05-28	Pharmaceutical compositions containing triazolo-isoquinoline derivatives
IL44222A (en)	1978-01-31	Diphenylpropylamines their preparation and pharmaceutical compositions containing them
AU7201374A (en)	1976-02-05	Pharmaceutical compositions
ZA745756B (en)	1975-10-29	Pharmaceutical compositions
ZA744488B (en)	1975-07-30	Pharmaceutical compositions
PH11231A (en)	1977-10-28	Piperidinesulfonylurea derivatives and pharmaceutical compositions containing them
ZA742064B (en)	1975-03-26	Pharmaceutical compositions
ZA747276B (en)	1976-07-28	Pharmaceutical compositions
IL45950A (en)	1978-01-31	2-glycylamido-4-pyridyl-thiazole derivatives their preparation and pharmaceutical compositions containing them
IE39291B1 (en)	1978-09-13	Pharmaceutical compositions comprising an anzyme and substtrate
PH11919A (en)	1978-09-08	Morpholine derivatives and their pharmaceutical compositions