PE20080422A1 - Composicion solida antirretroviral de administracion oral - Google Patents

Composicion solida antirretroviral de administracion oral

Info

Publication number
PE20080422A1
PE20080422A1 PE2007001072A PE2007001072A PE20080422A1 PE 20080422 A1 PE20080422 A1 PE 20080422A1 PE 2007001072 A PE2007001072 A PE 2007001072A PE 2007001072 A PE2007001072 A PE 2007001072A PE 20080422 A1 PE20080422 A1 PE 20080422A1
Authority
PE
Peru
Prior art keywords
composition
polymer
refers
vinyl acetate
solid
Prior art date
Application number
PE2007001072A
Other languages
English (en)
Inventor
Amar Lulla
Geena Malhotra
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of PE20080422A1 publication Critical patent/PE20080422A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA SOLIDA QUE COMPRENDE: A) DOS INHIBIDORES DE PROTEASA DEL VIRUS DE INMUNODEFICIENCIA HUMANA (VIH) TAL COMO LOPINAVIR, RITONAVIR, ENTRE OTROS; B) UN POLIMERO INSOLUBLE EN AGUA TAL COMO COPOLIMEROS ACRILICOS, POLI(ACETATO DE VINILO), ETILCELULOSA, ENTRE OTROS, EN DONDE LA RELACION DE FARMACO A POLIMERO EN LA COMPOSICION ES DE 1:1 A 1:6; C) UN POLIMERO SOLUBLE EN AGUA TAL COMO POLIVINILPIRROLIDONA, ACETATO DE VINILO, OXIDO DE POLIETILENO, ENTRE OTROS; D) UN PLASTIFICANTE TAL COMO MONOLAURATO DE SORBITAN, CITRATO DE TRIETILO, ENTRE OTROS, QUE SE ENCUENTRA EN UNA CANTIDAD DE HASTA 10%; E) AGENTES DE RELLENO TAL COMO SACARIDOS, CELULOSA EN POLVO, AZUCAR PURIFICADA, ENTRE OTROS; F) AGENTES DE SABOR TAL COMO ACIDO CITRICO, ACIDO TARTARICO, ACIDO LACTICO, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO DE PREPARACION. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE SIDA
PE2007001072A 2006-08-10 2007-08-10 Composicion solida antirretroviral de administracion oral PE20080422A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1269MU2006 2006-08-10
IN1227MU2007 2007-06-27

Publications (1)

Publication Number Publication Date
PE20080422A1 true PE20080422A1 (es) 2008-04-28

Family

ID=38667164

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007001072A PE20080422A1 (es) 2006-08-10 2007-08-10 Composicion solida antirretroviral de administracion oral

Country Status (9)

Country Link
US (1) US20100173921A1 (es)
AU (1) AU2007283196A1 (es)
BR (1) BRPI0714265A2 (es)
CA (1) CA2660374A1 (es)
CL (1) CL2007002331A1 (es)
PE (1) PE20080422A1 (es)
TW (1) TW200815033A (es)
UY (1) UY30535A1 (es)
WO (1) WO2008017867A2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR065439A1 (es) 2007-02-23 2009-06-10 Gilead Sciences Inc Derivados de tiazoles 1,3 no condensados,composiciones farmaceuticas que los contienen y usos como agentes antivirales, en particular anti hiv.
ES2553897T3 (es) 2008-05-02 2015-12-14 Gilead Sciences, Inc. El uso de partículas de vehículo sólido para mejorar la procesabilidad de un agente farmacéutico
WO2009153654A1 (en) * 2008-06-17 2009-12-23 Aurobindo Pharma Limited Solid dosage forms of antiretrovirals
KR20110081176A (ko) * 2008-10-03 2011-07-13 하. 룬드벡 아크티에셀스카브 경구용 제형물
JP5524220B2 (ja) 2008-10-07 2014-06-18 アストラゼネカ・ユーケイ・リミテッド 医薬配合物５１４
GB201006038D0 (en) 2010-04-12 2010-05-26 Unilever Plc Improvements relating to antiviral compositions
CN102985074B (zh) * 2010-05-10 2015-09-02 赢创罗姆有限公司 包含一种或多种抗逆转录病毒活性成分的药物剂型
KR101944124B1 (ko) * 2010-11-24 2019-01-30 멜린타 서브시디어리 코프. 약학 조성물
GB201118182D0 (en) * 2011-10-21 2011-12-07 Jagotec Ag Improvements in or relating to organic compounds
US9370578B2 (en) * 2012-03-07 2016-06-21 Ratiopharm Gmbh Dosage form comprising lopinavir and ritonavir
CN104411300A (zh) 2012-05-03 2015-03-11 希普拉有限公司 抗逆转录病毒组合物
TWI690322B (zh) * 2012-10-02 2020-04-11 法商傳斯堅公司 含病毒的調配物及其使用
WO2014080365A1 (en) * 2012-11-23 2014-05-30 Ranbaxy Laboratories Limited Method of reducing an unpleasant odor of a pharmaceutical composition
RU2505286C1 (ru) * 2012-12-29 2014-01-27 Открытое Акционерное Общество "Фармасинтез" Фармацевтическая композиция для лечения вич-инфекции, способ ее получения и способ лечения
CN103550993B (zh) * 2013-10-30 2015-07-08 王维玲 一种大气污染洁净剂及制备方法、洁净剂的应用及应用方法
PE20171319A1 (es) * 2015-01-27 2017-09-07 Janssen Pharmaceutica Nv Composiciones dispersables
PL3398587T3 (pl) * 2015-12-28 2024-01-22 Ssp Co., Ltd., Japan Skompaktowany preparat farmaceutyczny
GB2625584A (en) * 2022-12-21 2024-06-26 Rb Health Us Llc Novel composition

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696270A (en) * 1989-05-23 1997-12-09 Abbott Laboratories Intermediate for making retroviral protease inhibiting compounds
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
JP4101661B2 (ja) * 2001-05-03 2008-06-18 エフ．ホフマン−ラ ロシュ アーゲー 非晶質メシル酸ネルフィナビルの製薬剤形
DE10247037A1 (de) * 2002-10-09 2004-04-22 Abbott Gmbh & Co. Kg Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) * 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US20050048112A1 (en) * 2003-08-28 2005-03-03 Jorg Breitenbach Solid pharmaceutical dosage form
WO2007013047A2 (en) * 2005-07-29 2007-02-01 Ranbaxy Laboratories Limited Water-dispersible anti-retroviral pharmaceutical compositions
US20090011007A1 (en) * 2006-02-03 2009-01-08 Evonik Roehm Gmbh Pharmaceutical Compositions Containing Mixtures of Polymers and Active Agents Poorly Soluble in Water

Also Published As

Publication number Publication date
US20100173921A1 (en) 2010-07-08
WO2008017867A3 (en) 2009-04-16
TW200815033A (en) 2008-04-01
WO2008017867A2 (en) 2008-02-14
CA2660374A1 (en) 2008-02-14
CL2007002331A1 (es) 2008-04-18
UY30535A1 (es) 2008-03-31
AU2007283196A1 (en) 2008-02-14
BRPI0714265A2 (pt) 2013-04-16

Similar Documents

Publication Publication Date Title
PE20080422A1 (es) Composicion solida antirretroviral de administracion oral
RU2420284C2 (ru) Антагонист ccr5 для усиления иммуновосстановительной терапии и лечения оппортунистической инфекции у пациентов с вич
HRP20211543T1 (hr) Derivati kinazolina koji se koriste za liječenje hiv-a
AU2013336491B2 (en) Pharmaceutical antiretroviral composition
PE20100123A1 (es) Una formulacion solida de dosificacion farmaceutica
MD20070267A (en) Gastroresistant pharmaceutical formulation containing rifaximin
AR048439A1 (es) Composiciones farmaceuticas y metodos para tratar la infeccion por vih
PE20091530A1 (es) Combinacion anti-retroviral
TW200916103A (en) Therapeutic compositions and methods
EA201190161A1 (ru) Способ получения твердых лекарственных форм солифенацина и его фармацевтически приемлемых солей для перорального введения
WO2013034927A8 (en) Compositions of lopinavir and ritonavir
UA102885C2 (ru) Таблетка для орального введения, которая содержит тамсулозин и солифенацин
WO2011151722A3 (en) Methods and compositions for oral pharmaceutical therapy
WO2007064448A3 (en) Cancer treatment using fts and 2-deoxyglucose
MX2019001032A (es) Formulacion que tiene caracteristicas mejoradas de liberacion de farmacos ph dependientes, que contienen esomeprazol o una de sus sales farmaceuticas aceptable.
CN105663096B (zh) 一种沃诺拉赞口腔速溶膜剂及其制备方法
EA201691490A1 (ru) Фармацевтическая композиция, содержащая бринзоламид
CN103784426B (zh) 阿立哌唑口溶膜剂及其制备方法
JP2018039810A5 (es)
DK3193826T3 (en) ORODISPERSIBLE MOVIE COMPOSITION, INCLUDING ENALAPRIL FOR TREATMENT OF HYPERTENSION OF A PEDIATRIC POPULATION
JP5848432B2 (ja) ミルタザピンを含有する口腔内崩壊錠
KR102272442B1 (ko) 계면활성제 또는 폴리알콜을 포함하지 않은 즉각적 습윤성의 경구용 필름 제형
JP6549428B2 (ja) 経口組成物
NZ584968A (en) Novel antiretroviral combination comprising ritonavir and atazanavir
WO2020053658A3 (en) Non-aqueous chemotherapeutic solutions for oral dosage

Legal Events

Date Code Title Description
FC Refusal