PA8790101A1 - Derivados de aminoalquilazol como antagonistas de histamina-3 - Google Patents
Derivados de aminoalquilazol como antagonistas de histamina-3Info
- Publication number
- PA8790101A1 PA8790101A1 PA20088790101A PA8790101A PA8790101A1 PA 8790101 A1 PA8790101 A1 PA 8790101A1 PA 20088790101 A PA20088790101 A PA 20088790101A PA 8790101 A PA8790101 A PA 8790101A PA 8790101 A1 PA8790101 A1 PA 8790101A1
- Authority
- PA
- Panama
- Prior art keywords
- histamine
- aminoalquilazol
- antagonists
- derivatives
- affected
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA PRESENTE INVENCIÓN PROPORCIONA UN COMPUESTO DE FÓRMULA 1:Y EL USO DE ESTE PARA EL TRATAMIENTO DE UN TRASTORNO DEL SISTEMA NERVIOSO CENTRAL RELACIONADO CON O AFECTADO POR EL RECEPTOR DE HISTAMINA-3.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95974107P | 2007-07-16 | 2007-07-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8790101A1 true PA8790101A1 (es) | 2009-02-09 |
Family
ID=39708793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20088790101A PA8790101A1 (es) | 2007-07-16 | 2008-07-16 | Derivados de aminoalquilazol como antagonistas de histamina-3 |
Country Status (10)
Country | Link |
---|---|
US (1) | US7803825B2 (es) |
EP (1) | EP2170875A1 (es) |
JP (1) | JP2010533725A (es) |
AR (1) | AR067549A1 (es) |
CA (1) | CA2693138A1 (es) |
CL (1) | CL2008002088A1 (es) |
PA (1) | PA8790101A1 (es) |
PE (1) | PE20090812A1 (es) |
TW (1) | TW200920356A (es) |
WO (1) | WO2009012252A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010009029A2 (en) * | 2008-07-15 | 2010-01-21 | Wyeth | Methods for the preparation of azole compounds |
EP2445899B1 (en) * | 2009-06-26 | 2016-05-11 | Sanofi | Novel fumarate salts of a histamine h3 receptor antagonist |
WO2011006903A1 (en) * | 2009-07-15 | 2011-01-20 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc | Substituted triazole and imidazole derivatives as gamma secretase modulators |
JP2013508461A (ja) * | 2009-10-27 | 2013-03-07 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 脂肪酸シンターゼ阻害剤としてのベンズイミダゾール |
WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
CN103570705B (zh) * | 2012-07-18 | 2017-01-25 | 中国医学科学院医药生物技术研究所 | 取代的n‑((1',3'‑杂唑‑4'‑基)‑甲基)‑4‑苯甲酰基六氢吡啶类化合物及其用途 |
ES2775782T3 (es) | 2016-03-15 | 2020-07-28 | Bayer Cropscience Ag | Sulfonilamidas sustituidas para combatir parásitos animales |
WO2023140709A1 (ko) * | 2022-01-21 | 2023-07-27 | 재단법인 한국파스퇴르연구소 | 항박테리아 활성 옥사졸 유도체 화합물 및 이의 의약 용도 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1416872A (en) | 1972-03-10 | 1975-12-10 | Wyeth John & Brother Ltd | 4-aminoquinoline derivatives |
US3933829A (en) * | 1974-08-22 | 1976-01-20 | John Wyeth & Brother Limited | 4-Aminoquinoline derivatives |
US4168853A (en) * | 1977-06-08 | 1979-09-25 | Vetco, Inc. | Shiftable ring gasket retainer for flanged connectors |
US4166853A (en) | 1978-05-05 | 1979-09-04 | The Upjohn Company | Antihypertensive 7-trifluoromethyl-4-aminoquinolones |
US4159331A (en) * | 1978-05-05 | 1979-06-26 | The Upjohn Company | Antihypertensive 4-aminoquinolines |
AU674207B2 (en) | 1993-04-07 | 1996-12-12 | Otsuka Pharmaceutical Co., Ltd. | N-acylated 4-amino piperidine derivatives |
IL117149A0 (en) * | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
ES2210747T3 (es) * | 1997-05-01 | 2004-07-01 | Eli Lilly And Company | Agentes antitromboticos. |
WO2001042224A1 (en) | 1999-12-09 | 2001-06-14 | Mitsubishi Pharma Corporation | Carboxyamido derivatives |
WO2001074773A2 (en) | 2000-03-31 | 2001-10-11 | Ortho Mcneil Pharmaceutical, Inc. | Phenyl-substituted indoles as histamine h3-receptor antagonists |
HN2002000156A (es) | 2001-07-06 | 2003-11-27 | Inc Agouron Pharmaceuticals | Derivados de benzamida tiazol y composiciones farmaceuticas para inhibir la proliferacion de celulas y metodos para su utilización. |
DE60329910D1 (de) | 2002-03-29 | 2009-12-17 | Novartis Vaccines & Diagnostic | Substituierte benzazole und ihre verwendung als raf-kinase-hemmer |
EP1603917B1 (en) | 2003-03-14 | 2010-11-24 | MediGene Ltd. | Immunomodulating heterocyclic compounds |
MY139355A (en) * | 2004-05-14 | 2009-09-30 | Millennium Pharm Inc | Compounds and methods for inhibiting mitotic progression by inhibition of aurora kinase |
TW200602314A (en) | 2004-05-28 | 2006-01-16 | Tanabe Seiyaku Co | A novel pyrrolidine compound and a process for preparing the same |
US20060014733A1 (en) * | 2004-07-19 | 2006-01-19 | Pfizer Inc | Histamine-3 agonists and antagonists |
DK1786790T3 (da) * | 2004-07-26 | 2009-07-20 | Lilly Co Eli | Oxazolderivater som histamin H3 receptorstoffer, fremstilling og terapeutiske anvendelser |
US7705025B2 (en) | 2004-08-23 | 2010-04-27 | Eli Lilly And Company | Histamine H3 receptor agents, preparation and therapeutic uses |
UY29149A1 (es) | 2004-10-07 | 2006-05-31 | Boehringer Ingelheim Int | Tiazolil-dihidro-indazoles |
US7381732B2 (en) * | 2004-10-26 | 2008-06-03 | Bristol-Myers Squibb Company | Pyrazolobenzamides and derivatives as factor Xa inhibitors |
WO2006078775A1 (en) * | 2005-01-21 | 2006-07-27 | Schering Corporation | Imidazole and benzimidazole derivatives useful as histamine h3 antagonists |
US20070032475A1 (en) | 2005-04-15 | 2007-02-08 | Ye Xiaocong M | Novel compounds useful for bradykinin B1 receptor antagonism |
CA2645731A1 (en) | 2006-03-15 | 2007-09-27 | Wyeth | N-substituted-azacyclylamines as histamine-3 antagonists |
AR059961A1 (es) | 2006-03-20 | 2008-05-14 | Glaxo Group Ltd | Compuesto derivado de fenil tetrahidro-indazol, composiciones farmaceuticas que lo comprenden, usos para preparar un medicamento para el tratamiento de una enfermedad mediada por una reduccion o desequilibrio en la funcion del receptor de glutamato y procesos para su preparacion |
US20070238718A1 (en) | 2006-04-06 | 2007-10-11 | Matthias Grauert | Thiazolyl-dihydro-indazole |
PE20081152A1 (es) | 2006-10-06 | 2008-08-10 | Wyeth Corp | Azaciclilaminas n-sustituidas como antagonistas de histamina-3 |
-
2008
- 2008-07-15 AR ARP080103037A patent/AR067549A1/es unknown
- 2008-07-15 CA CA2693138A patent/CA2693138A1/en not_active Abandoned
- 2008-07-15 EP EP08781841A patent/EP2170875A1/en not_active Withdrawn
- 2008-07-15 US US12/173,255 patent/US7803825B2/en not_active Expired - Fee Related
- 2008-07-15 PE PE2008001183A patent/PE20090812A1/es not_active Application Discontinuation
- 2008-07-15 JP JP2010517115A patent/JP2010533725A/ja not_active Withdrawn
- 2008-07-15 CL CL200802088A patent/CL2008002088A1/es unknown
- 2008-07-15 WO PCT/US2008/070048 patent/WO2009012252A1/en active Application Filing
- 2008-07-16 TW TW097127000A patent/TW200920356A/zh unknown
- 2008-07-16 PA PA20088790101A patent/PA8790101A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2010533725A (ja) | 2010-10-28 |
CL2008002088A1 (es) | 2008-09-05 |
WO2009012252A1 (en) | 2009-01-22 |
EP2170875A1 (en) | 2010-04-07 |
US7803825B2 (en) | 2010-09-28 |
CA2693138A1 (en) | 2009-01-22 |
PE20090812A1 (es) | 2009-06-14 |
US20090023707A1 (en) | 2009-01-22 |
TW200920356A (en) | 2009-05-16 |
AR067549A1 (es) | 2009-10-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PA8795601A1 (es) | Derivados de azaciclilisoquinolinona e isoindolinona como antagonistas de histamina-3 | |
PA8795701A1 (es) | Derivados de isoquinolinilo e isoindolinilo como antagonistas de histamina-3 | |
ECSP055535A (es) | Derivados de 1-heterociclialquil-3-sulfonilazaindol o azaindol como ligandos de 5-hidroxitriptamina-6 | |
PA8790101A1 (es) | Derivados de aminoalquilazol como antagonistas de histamina-3 | |
TW200800958A (en) | N-substituted-azacyclylamines as histamine-3 antagonists | |
ECSP055536A (es) | Derivados de 1-heterociclilalquil-3-sulfonilindol o indazol como ligandos de 5-hidroxitriptamina-6 | |
CR10309A (es) | "compuestos y composiciones como inhibidores de la actividad del receptor canabinoide 1" | |
CO6361994A2 (es) | Antagonistas del receptor de orexina de isonicotinamida | |
CL2007001670A1 (es) | Uso de compuestos derivados de amina para el tratamiento de un trastorno mediado por citoquinas. | |
GT200600030A (es) | 2-fenil-indoles como antagonistas del receptor de la prostaglandina d2 | |
GT200500185A (es) | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
ECSP099553A (es) | Compuestos triciclicos y su uso como moduladores del receptor de glucocorticosteroides | |
PA8781601A1 (es) | " derivados de azaciclilbenzamida como antagonistas de histamina-3 | |
WO2007136668A3 (en) | N-benzoyl-and n-benzylpyrrolidin-3-ylamines as histamine-3 antagonists | |
CR20140085A (es) | Inhibidores de pde10 de pirimidina | |
MX2009003645A (es) | Azaciclilaminas n-sustituidas como antagonistas de histamina-3. | |
ECSP045473A (es) | Derivados de 1-(aminoalquil)-3-sulfonilindol y 1-aminoalquil-3-sulfonilindazol como ligandos de 5-hidroxitriptamina-6 | |
ECSP088176A (es) | Derivados de azinil-3-sulfonilindazol como ligandos de5-hidroxitriptamina-6 | |
CR9734A (es) | Derivados de 3-sulfonilindazol sustituido como ligandos de 5-hidroxitriptamina-6 | |
CL2008002767A1 (es) | Compuestos derivados de heterociclico triciclico; composicion farmaceutica; y su uso para el tratamiento de un trastorno mediado por serotonina tal como obesidad, esquizofrenia y disfuncion cognitiva. | |
CO6341625A2 (es) | Derivados de indol como agentes anticáncer | |
ECSP088930A (es) | Derivados de benzoxazol y benzotiazol como ligandos de | |
ECSP088789A (es) | Derivados de sulfonil-3-heterociclilindazol como ligandos de 5-hidroxitriptamina-6 | |
AR073708A1 (es) | Compuestos intermediarios de tiazolil -pirazolopirimidina y procesos sinteticos que los incluyen | |
UY31931A (es) | Compuestos de diarilo y uso de los mismos |