PA8481901A1 - ADMINISTRATION OF ACTIVE AGENT IN DRY POWDER - Google Patents
ADMINISTRATION OF ACTIVE AGENT IN DRY POWDERInfo
- Publication number
- PA8481901A1 PA8481901A1 PA19998481901A PA8481901A PA8481901A1 PA 8481901 A1 PA8481901 A1 PA 8481901A1 PA 19998481901 A PA19998481901 A PA 19998481901A PA 8481901 A PA8481901 A PA 8481901A PA 8481901 A1 PA8481901 A1 PA 8481901A1
- Authority
- PA
- Panama
- Prior art keywords
- active agent
- administration
- dry powder
- inhibitor
- hygroscopic growth
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
PARTICULAS PARA LA ADMINISTRACION DE UN AGENTE ACTIVO A LOS ALVEOLOS DE UN PACIENTE HUMANO, PARTICULAS QUE CONTIENEN EL AGENTE ACTIVO Y UN INHIBIDOR DEL CRECIMIENTO HIGROSCOPICO, DONDE EL INHIBIDOR DEL CRECIMIENTO HIGROSCOPICO ESTA INCORPORADO AL INTERIOR DE LAS PARTICULAS Y DONDE LAS PARTICULAS EXHIBEN UNA CAIDA DE LA DOSIS EMITIDA, EN CONDICIONES PULMONARES SIMULADAS, DE NO MAS DE APROXIMADAMENTE 25%.PARTICLES FOR THE ADMINISTRATION OF AN ACTIVE AGENT TO THE HELLS OF A HUMAN PATIENT, PARTICLES CONTAINING THE ACTIVE AGENT AND AN INHIBITOR OF HYGROSCOPIC GROWTH, WHERE THE INHIBITOR OF HYGROSCOPIC GROWTH IS INCORPORATED TO THE INSIDE OF PARTICULAS THE DOSE ISSUED, IN SIMULATED PULMONARY CONDITIONS, OF NO MORE THAN APPROXIMATELY 25%.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10016398P | 1998-09-14 | 1998-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PA8481901A1 true PA8481901A1 (en) | 2002-04-25 |
Family
ID=22278404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PA19998481901A PA8481901A1 (en) | 1998-09-14 | 1999-09-14 | ADMINISTRATION OF ACTIVE AGENT IN DRY POWDER |
Country Status (44)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000075281A2 (en) | 1999-06-09 | 2000-12-14 | University Technology Corporation | Supercritical fluid-assisted nebulization and bubble drying |
| US6475468B2 (en) * | 2001-02-15 | 2002-11-05 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| EP1392262A1 (en) * | 2001-05-24 | 2004-03-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| EG24184A (en) | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
| US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
| CZ2004904A3 (en) | 2002-02-25 | 2004-12-15 | Diffusion Pharmaceuticals Llc | Bipolar carotenoid salts and use thereof |
| AU2003232081B2 (en) * | 2002-07-03 | 2009-02-05 | Brandeis University | Central airway administration for systemic delivery of therapeutics |
| MXPA05006802A (en) * | 2002-12-19 | 2005-09-08 | Pharmacia Corp | Non-hygroscopic formulation comprising a hydroscopic drug. |
| DE10338403A1 (en) * | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder formulation containing the CGRP antagonist 1- [N 2 - [3,5-dibromo-N - [[4- (3,4-dihydro-2 (1 H) -oxoquinazolin-3-yl] -1-piperidinyl] carbonyl] -D-tyrosyl] -L-lysyl] -4- (4-pyrindinyl) piperazine, process for its preparation and its use as inhalant |
| GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
| US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
| WO2005104712A2 (en) * | 2004-04-23 | 2005-11-10 | Cydex, Inc. | Dpi formulation containing sulfoalkyl ether cyclodextrin |
| CN104840455A (en) | 2005-02-24 | 2015-08-19 | 扩散药品有限公司 | Trans carotenoids, their synthesis, formulation and uses |
| AU2006221364A1 (en) * | 2005-03-09 | 2006-09-14 | Ono Pharmaceutical Co., Ltd. | Particle and preparation containing the particle |
| US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
| PL2581078T3 (en) | 2005-10-26 | 2015-07-31 | Cydex Pharmaceuticals Inc | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
| US20080035143A1 (en) * | 2006-08-14 | 2008-02-14 | Sievers Robert E | Human-powered dry powder inhaler and dry powder inhaler compositions |
| WO2008050847A1 (en) * | 2006-10-25 | 2008-05-02 | Dainippon Sumitomo Pharma Co., Ltd. | Granular preparation prevented from caking |
| EP1925295A1 (en) * | 2006-11-22 | 2008-05-28 | Boehringer Ingelheim Pharma GmbH & Co. KG | Stable powder formulation containing a new antichinolinergic agent |
| EP2146948A4 (en) | 2007-04-13 | 2010-08-04 | Diffusion Pharmaceuticals Llc | Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease |
| MX2010004803A (en) | 2007-10-31 | 2010-09-09 | Diffusion Pharmaceuticals Llc | A new class of therapeutics that enhance small molecule diffusion. |
| PL2432502T3 (en) | 2009-05-20 | 2018-05-30 | Aeras | Stable, spray dried, immunogenic, viral compositions |
| EP2445339B1 (en) | 2009-06-22 | 2019-08-07 | Diffusion Pharmaceuticals LLC | Diffusion enhancing compound and its use with a thrombolytic |
| CN103124498A (en) | 2010-06-02 | 2013-05-29 | 扩散药品有限公司 | Oral formulations of bipolar trans carotenoids |
| KR102240042B1 (en) | 2012-05-03 | 2021-04-14 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections |
| WO2014074797A1 (en) * | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
| WO2015042352A1 (en) * | 2013-09-20 | 2015-03-26 | Virginia Commonwealth University | Delivery of particles using hygroscopic excipients |
| MX2017005692A (en) | 2014-10-31 | 2017-08-07 | Glaxosmithkline Ip Dev Ltd | Powder formulation. |
| KR102489034B1 (en) | 2016-03-24 | 2023-01-13 | 디퓨젼 파마슈티컬즈 엘엘씨 | Use of Bipolar Trans Carotenoids with Chemotherapy and Radiation Therapy to Treat Cancer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3155573A (en) * | 1958-05-06 | 1964-11-03 | Benger Lab Ltd | Inhalant composition and method of making same |
| DE69332240T2 (en) * | 1992-06-12 | 2003-04-10 | Teijin Ltd | ULTRA FINE POWDER FOR INHALATION AND PRODUCTION |
| US6524557B1 (en) * | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| ES2236832T3 (en) * | 1997-01-16 | 2005-07-16 | Massachusetts Institute Of Technology | PREPARATION OF PARTICLES FOR INHALATION. |
| US6086376A (en) * | 1998-01-30 | 2000-07-11 | Rtp Pharma Inc. | Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant |
-
1999
- 1999-09-09 MA MA25762A patent/MA25590A1/en unknown
- 1999-09-13 BR BR9913722-4A patent/BR9913722A/en not_active IP Right Cessation
- 1999-09-13 WO PCT/US1999/021109 patent/WO2000015262A1/en not_active Application Discontinuation
- 1999-09-13 AU AU60397/99A patent/AU753014B2/en not_active Ceased
- 1999-09-13 CN CN99810871A patent/CN1317977A/en active Pending
- 1999-09-13 HN HN1999000159A patent/HN1999000159A/en unknown
- 1999-09-13 EP EP99969035A patent/EP1117442A1/en not_active Withdrawn
- 1999-09-13 UA UA2001031707A patent/UA76085C2/en unknown
- 1999-09-13 IL IL14156299A patent/IL141562A0/en not_active IP Right Cessation
- 1999-09-13 CZ CZ2001829A patent/CZ2001829A3/en unknown
- 1999-09-13 PL PL99346768A patent/PL195574B1/en not_active IP Right Cessation
- 1999-09-13 ZA ZA200101995A patent/ZA200101995B/en unknown
- 1999-09-13 CA CA002343920A patent/CA2343920A1/en not_active Abandoned
- 1999-09-13 PE PE1999000925A patent/PE20001061A1/en not_active Application Discontinuation
- 1999-09-13 HU HU0103837A patent/HUP0103837A3/en unknown
- 1999-09-13 YU YU24201A patent/YU24201A/en unknown
- 1999-09-13 SK SK344-2001A patent/SK3442001A3/en unknown
- 1999-09-13 OA OA1200100063A patent/OA11781A/en unknown
- 1999-09-13 AP APAP/P/2001/002093A patent/AP1374A/en active
- 1999-09-13 NZ NZ510168A patent/NZ510168A/en unknown
- 1999-09-13 EE EEP200100151A patent/EE200100151A/en unknown
- 1999-09-13 GE GEAP19995857A patent/GEP20043257B/en unknown
- 1999-09-13 DZ DZ990192A patent/DZ2892A1/en active
- 1999-09-13 EA EA200100300A patent/EA003476B1/en active IP Right Revival
- 1999-09-13 AR ARP990104587A patent/AR022090A1/en unknown
- 1999-09-13 ID IDW20010582A patent/ID28845A/en unknown
- 1999-09-13 MY MYPI99003947A patent/MY129282A/en unknown
- 1999-09-13 TR TR2001/01182T patent/TR200101182T2/en unknown
- 1999-09-13 JP JP2000569846A patent/JP2002524535A/en not_active Withdrawn
- 1999-09-13 KR KR1020017003208A patent/KR20010075063A/en not_active Application Discontinuation
- 1999-09-13 TW TW088115876A patent/TWI226248B/en not_active IP Right Cessation
- 1999-09-14 CO CO99058265A patent/CO5130023A1/en unknown
- 1999-09-14 PA PA19998481901A patent/PA8481901A1/en unknown
- 1999-09-14 TN TNTNSN99173A patent/TNSN99173A1/en unknown
- 1999-09-14 UY UY25711A patent/UY25711A1/en not_active Application Discontinuation
- 1999-09-14 GT GT199900156A patent/GT199900156A/en unknown
- 1999-10-31 SA SA99200718A patent/SA99200718B1/en unknown
-
2001
- 2001-02-21 IL IL141562A patent/IL141562A/en unknown
- 2001-03-05 IS IS5878A patent/IS5878A/en unknown
- 2001-03-13 NO NO20011251A patent/NO20011251L/en not_active Application Discontinuation
- 2001-03-14 LV LV010041A patent/LV12658B/en unknown
- 2001-03-14 HR HR20010189A patent/HRP20010189A2/en not_active Application Discontinuation
- 2001-03-14 LT LT2001021A patent/LT4897B/en not_active IP Right Cessation
- 2001-04-10 BG BG105430A patent/BG105430A/en unknown
-
2002
- 2002-03-06 HK HK02101738.3A patent/HK1042231A1/en unknown
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