OA08187A - Dérivés à cycle imidique de 2-(4-butylpipérazine-1-yl) pyridines et leur application antipsychotique. - Google Patents

Dérivés à cycle imidique de 2-(4-butylpipérazine-1-yl) pyridines et leur application antipsychotique.

Info

Publication number
OA08187A
OA08187A OA58765A OA58765A OA08187A OA 08187 A OA08187 A OA 08187A OA 58765 A OA58765 A OA 58765A OA 58765 A OA58765 A OA 58765A OA 08187 A OA08187 A OA 08187A
Authority
OA
OAPI
Prior art keywords
butylpiperazin
imidic
antipsychotic
pyridines
ring
Prior art date
Application number
OA58765A
Other languages
English (en)
French (fr)
Inventor
James Stewart New
Walter G Lobeck Jr
Joseph P Yevich
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of OA08187A publication Critical patent/OA08187A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
OA58765A 1985-01-16 1986-01-15 Dérivés à cycle imidique de 2-(4-butylpipérazine-1-yl) pyridines et leur application antipsychotique. OA08187A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/691,952 US4619930A (en) 1985-01-16 1985-01-16 Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use

Publications (1)

Publication Number Publication Date
OA08187A true OA08187A (fr) 1987-10-30

Family

ID=24778661

Family Applications (1)

Application Number Title Priority Date Filing Date
OA58765A OA08187A (fr) 1985-01-16 1986-01-15 Dérivés à cycle imidique de 2-(4-butylpipérazine-1-yl) pyridines et leur application antipsychotique.

Country Status (29)

Country Link
US (1) US4619930A (de)
JP (1) JPH0780873B2 (de)
KR (1) KR900000366B1 (de)
CN (1) CN1016691B (de)
AT (1) AT391698B (de)
AU (1) AU591473B2 (de)
BE (1) BE904047A (de)
CA (1) CA1284325C (de)
CH (1) CH666269A5 (de)
DE (1) DE3601143C2 (de)
DK (1) DK19286A (de)
EG (1) EG17759A (de)
ES (2) ES8705869A1 (de)
FI (1) FI90077C (de)
FR (1) FR2580282B1 (de)
GB (1) GB2191772B (de)
HU (1) HU198202B (de)
IE (1) IE58866B1 (de)
IL (1) IL77577A (de)
IT (1) IT1214497B (de)
LU (1) LU86248A1 (de)
NL (1) NL8600071A (de)
NZ (1) NZ214790A (de)
OA (1) OA08187A (de)
PT (1) PT81843B (de)
SE (1) SE466310B (de)
SU (1) SU1521282A3 (de)
YU (1) YU45757B (de)
ZA (1) ZA859692B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677104A (en) * 1985-05-06 1987-06-30 Bristol-Myers Company Antipsychotic fused-ring pyridinylpiperazine derivatives
US4812567A (en) * 1985-10-16 1989-03-14 American Home Products Corporation Polycyclic spiroimides with psychotropic activity
MX174210B (es) * 1987-02-17 1994-04-28 Pfizer Procedimiento para la preparacion de compuestos arilpiperazinil-alquilenfenil-p-heterociclicos
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
ES2052675T3 (es) * 1987-11-20 1994-07-16 Hoechst Roussel Pharma 3-(4-piperazinil-sustituido en 1)butil)-4-tiazolidinonas, un procedimiento para su preparacion y su uso como medicamentos.
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US5116970A (en) * 1988-02-18 1992-05-26 New James S Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
ES2084763T3 (es) * 1990-10-23 1996-05-16 Akzo Nobel Nv 4-(4- o 6-(2-trifluormetil piridinil))1-piperazinilalquilo lactamas sustituidas.
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
CN104230915B (zh) * 2014-08-29 2016-08-17 南京大学 含噻唑烷二酮的苯基哌嗪衍生物及其制备方法与用途
CN104513198A (zh) * 2014-11-29 2015-04-15 南京红太阳生物化学有限责任公司 一种2-氯烟酸的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
AT330777B (de) * 1973-09-08 1976-07-26 Thomae Gmbh Dr K Verfahren zur herstellung von neuen isochinolinderivaten und deren salzen
US4305944A (en) * 1980-09-08 1981-12-15 Mead Johnson & Company N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
US4456756A (en) * 1981-08-03 1984-06-26 Mead Johnson & Company Spirothiazolidinyl piperazine derivatives
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
DE3135532A1 (de) * 1981-09-08 1983-03-24 NPL po Dvigateli s Vatrešno Gorene, Varna Brennkraftmaschine
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
JPS5976059A (ja) * 1982-10-21 1984-04-28 Sumitomo Chem Co Ltd 環状イミド誘導体及びその酸付加塩
JPS61238784A (ja) * 1985-04-17 1986-10-24 Sumitomo Seiyaku Kk コハク酸イミド誘導体及びその酸付加塩
DE3529872A1 (de) * 1985-08-21 1987-02-26 Kali Chemie Pharma Gmbh Neue tetraoxoverbindungen

Also Published As

Publication number Publication date
IL77577A (en) 1990-02-09
SE8600173L (sv) 1986-07-17
IE860125L (en) 1986-07-16
FI90077C (fi) 1993-12-27
BE904047A (fr) 1986-07-15
ES8801822A1 (es) 1988-02-16
JPS61167682A (ja) 1986-07-29
CN1016691B (zh) 1992-05-20
ES550829A0 (es) 1987-05-16
FI860136A (fi) 1986-07-17
CA1284325C (en) 1991-05-21
YU45757B (sh) 1992-07-20
FR2580282B1 (fr) 1992-10-16
EG17759A (en) 1991-03-30
AT391698B (de) 1990-11-12
DK19286A (da) 1986-07-17
GB8614686D0 (en) 1986-07-23
SE8600173D0 (sv) 1986-01-15
PT81843B (pt) 1988-05-27
AU591473B2 (en) 1989-12-07
CN86100224A (zh) 1986-11-19
HU198202B (en) 1989-08-28
LU86248A1 (fr) 1986-08-04
ZA859692B (en) 1986-07-14
HUT39743A (en) 1986-10-29
ATA10086A (de) 1990-05-15
AU5229486A (en) 1986-07-24
US4619930A (en) 1986-10-28
IT8619081A0 (it) 1986-01-15
DE3601143C2 (de) 1994-05-11
KR860005808A (ko) 1986-08-13
ES557390A0 (es) 1988-02-16
IT1214497B (it) 1990-01-18
YU4186A (en) 1987-10-31
NZ214790A (en) 1989-04-26
DK19286D0 (da) 1986-01-15
JPH0780873B2 (ja) 1995-08-30
NL8600071A (nl) 1986-08-18
ES8705869A1 (es) 1987-05-16
PT81843A (en) 1986-02-01
FR2580282A1 (fr) 1986-10-17
GB2191772A (en) 1987-12-23
CH666269A5 (de) 1988-07-15
DE3601143A1 (de) 1986-07-17
IE58866B1 (en) 1993-11-17
SE466310B (sv) 1992-01-27
FI860136A0 (fi) 1986-01-13
KR900000366B1 (ko) 1990-01-25
GB2191772B (en) 1990-05-23
FI90077B (fi) 1993-09-15
SU1521282A3 (ru) 1989-11-07

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