NO964686D0 - Aminometyl-2,3,8,9-tetrahydro-7H-1,4-dioksono [2,3-eÅ-indol-8-oner og derivater - Google Patents

Aminometyl-2,3,8,9-tetrahydro-7H-1,4-dioksono [2,3-eÅ-indol-8-oner og derivater

Info

Publication number
NO964686D0
NO964686D0 NO964686A NO964686A NO964686D0 NO 964686 D0 NO964686 D0 NO 964686D0 NO 964686 A NO964686 A NO 964686A NO 964686 A NO964686 A NO 964686A NO 964686 D0 NO964686 D0 NO 964686D0
Authority
NO
Norway
Prior art keywords
dioxono
indol
aminomethyl
tetrahydro
ones
Prior art date
Application number
NO964686A
Other languages
English (en)
Other versions
NO317054B1 (no
NO964686L (no
Inventor
Gary Paul Stack
Richard Eric Mewshaw
Byron Abel Bravo
Young Hee Kang
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of NO964686D0 publication Critical patent/NO964686D0/no
Publication of NO964686L publication Critical patent/NO964686L/no
Publication of NO317054B1 publication Critical patent/NO317054B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
NO19964686A 1995-11-06 1996-11-05 Aminometyl-2,3,8,9-tetrahydro-7H-1,4-dioksono [2,3-e]-indol-8-oner og derivater, samt anvendelse av dem NO317054B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US728395P 1995-11-06 1995-11-06
US08/730,267 US5756532A (en) 1995-11-06 1996-10-15 Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives

Publications (3)

Publication Number Publication Date
NO964686D0 true NO964686D0 (no) 1996-11-05
NO964686L NO964686L (no) 1997-05-07
NO317054B1 NO317054B1 (no) 2004-08-02

Family

ID=26676776

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19964686A NO317054B1 (no) 1995-11-06 1996-11-05 Aminometyl-2,3,8,9-tetrahydro-7H-1,4-dioksono [2,3-e]-indol-8-oner og derivater, samt anvendelse av dem

Country Status (21)

Country Link
US (2) US5756532A (no)
EP (3) EP1726592A1 (no)
JP (1) JP4311770B2 (no)
KR (1) KR100566678B1 (no)
CN (1) CN1084748C (no)
AR (2) AR004284A1 (no)
AT (1) ATE349450T1 (no)
AU (1) AU701624B2 (no)
CA (1) CA2189524C (no)
CZ (1) CZ291731B6 (no)
DE (1) DE69636801T2 (no)
DK (1) DK1375503T3 (no)
ES (1) ES2277014T3 (no)
HU (1) HU224841B1 (no)
IL (1) IL119565A (no)
MX (1) MX9605367A (no)
NO (1) NO317054B1 (no)
NZ (1) NZ299693A (no)
PT (1) PT1375503E (no)
RU (1) RU2178416C2 (no)
SK (1) SK282168B6 (no)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9627005D0 (en) * 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents
GB9704948D0 (en) 1997-03-11 1997-04-30 Knoll Ag Therapeutic agents
US6362009B1 (en) 1997-11-21 2002-03-26 Merck & Co., Inc. Solid phase synthesis of heterocycles
US6350773B1 (en) * 1999-12-10 2002-02-26 American Home Products Corporation Therapeutic combinations of (S)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro 7H-1,4-dioxino{2,3-e}indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders
KR100772854B1 (ko) * 1999-12-10 2007-11-02 와이어쓰 (Ｓ)-2-(벤질아미노-메틸)-2,3,8,9-테트라하이드로-7Ｈ-1,4-디옥시노[2,3-ｅ]인돌-8-온 및 항정신병 제제의 배합물
US20060287335A1 (en) * 2000-11-28 2006-12-21 Wyeth Serotonergic agents for treating sexual dysfunction
US20060223824A1 (en) * 2000-11-28 2006-10-05 Wyeth Serotonergic agents
US6458802B1 (en) 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline
US6803368B2 (en) 2001-04-25 2004-10-12 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diaza-cyclopenta[a]naphthalene
WO2002088132A1 (en) 2001-04-26 2002-11-07 Wyeth Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-ht1aantagonists
US6800648B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one
BR0209342A (pt) * 2001-04-26 2004-06-15 Wyeth Corp Antidepressivos de azaheterociclilmetila derivados de 2,3 dihidro-1,4-dioxino[2,3-f]quinoxalina; método de tratamento usando tais compostos; processo para prepará-los
US6861427B2 (en) * 2001-04-26 2005-03-01 Wyeth Azabicyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-HT1A antagonists
US6800642B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-2,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
US6861434B2 (en) 2001-04-26 2005-03-01 Wyeth Antipsychotic aminomethyl derivatives of 1,3,7,8-tetrahydro-6,9-dioxa-1,3-diaza-cyclopenta[a]-naphthalen-2-one
US6800641B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-2,3-diaza-cyclopenta[a]naphthalene
US7008944B2 (en) * 2001-04-26 2006-03-07 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-Dioxino[2,3-f]quinoxaline
MXPA03009828A (es) * 2001-04-26 2005-03-07 Wyeth Corp Sssri) azaheterociclilmetil derivados de 7,8-dihidro-3h-t,9-dioxa-1,3-diazaciclopenta[a]naftaleno como agentes antidepresivos.
WO2002088129A1 (en) * 2001-04-26 2002-11-07 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinazoline
US6927226B2 (en) 2001-04-26 2005-08-09 Wyeth Antidepressant azaheterocyclymethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalene
US6906206B2 (en) 2001-04-30 2005-06-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
US6555560B2 (en) 2001-04-30 2003-04-29 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
AU2002309769B2 (en) 2001-05-17 2008-04-17 Wyeth Processes for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline
US6541502B1 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6541501B2 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
WO2003010169A1 (en) * 2001-07-25 2003-02-06 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 7, 8-dihydro-6h-5-oxa-1-aza-phenanthrene
US7153849B2 (en) * 2002-09-12 2006-12-26 Wyeth Antidepressant arylpiperazine derivatives of hetrocycle-fused benzodioxans
CN100352820C (zh) * 2002-09-12 2007-12-05 惠氏公司 抗抑郁的杂环稠合的苯并二噁烷的氮杂环甲基衍生物
US7135479B2 (en) 2002-09-12 2006-11-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans
US6800637B2 (en) * 2002-09-12 2004-10-05 Wyeth Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines
US6939877B2 (en) * 2002-09-12 2005-09-06 Wyeth Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
CN1874767A (zh) * 2003-10-29 2006-12-06 惠氏公司 包含aplindore和其衍生物的缓释药物组合物
WO2006089053A2 (en) 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
US20070027162A1 (en) * 2005-03-01 2007-02-01 Wyeth Crystalline and amorphous 4-cyano-N-{(2R)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin -1-yl]-propyl}-N-pyridin-2-yl-benzamide hydrochloride
EP1871355A1 (en) * 2005-04-22 2008-01-02 Wyeth New therapeutic combianations for the treatment or prevention of depression
TW200811182A (en) 2006-05-25 2008-03-01 Wyeth Corp Oxindoledioxans, synthesis thereof, and intermediates thereto
WO2008118935A1 (en) * 2007-03-26 2008-10-02 Neurogen Corporation Compounds and processes for preparing substituted aminomethyl-2,3,8,9-tetrahydro-7h-1,4-dioxino[2,3-e]indol-8-ones
CN102378574B (zh) * 2009-03-30 2013-11-20 转化技术制药公司 取代的偶氮蒽衍生物、药物组合物及其使用方法
RU2554885C1 (ru) * 2014-05-27 2015-06-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) Антагонисты пуринорецепторов на основе новых производных пиридоксина
RU2554883C1 (ru) * 2014-05-27 2015-06-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) Применение производных ацеталей пиридоксина в качестве антагонистов пуринорецепторов

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2075057A1 (en) * 1990-03-15 1991-09-16 Pharmacia & Upjohn Company Llc Therapeutically useful heterocyclic indole compounds
US5189171A (en) * 1991-06-21 1993-02-23 American Home Products Corporation Antipsychotic benzodioxan derivatives
US5126366A (en) * 1991-06-21 1992-06-30 American Home Products Corporation Aminophenoxyalkyl derivatives of benzodioxan
US5166367A (en) * 1991-06-21 1992-11-24 American Home Products Corporation Antipsychotic benzodioxan derivatives
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
US5235055A (en) * 1992-09-02 1993-08-10 American Home Products Corporation Antipsychotic quinoline derivatives of benzodioxanmethylamine
US5245051A (en) * 1992-09-03 1993-09-14 American Home Products Corporation Antipsychotic chroman derivatives of benzodioxanmethylamine

Also Published As

Publication number Publication date
AR004284A1 (es) 1998-11-04
MX9605367A (es) 1997-10-31
KR100566678B1 (ko) 2006-11-30
HU9603057D0 (en) 1996-12-30
AR025698A1 (es) 2002-12-11
DE69636801D1 (de) 2007-02-08
CA2189524C (en) 2007-05-01
CZ324196A3 (en) 1997-12-17
IL119565A (en) 2002-11-10
AU7055396A (en) 1997-05-15
CN1084748C (zh) 2002-05-15
EP1726592A1 (en) 2006-11-29
DE69636801T2 (de) 2007-04-26
PT1375503E (pt) 2007-03-30
RU2178416C2 (ru) 2002-01-20
CA2189524A1 (en) 1997-05-07
DK1375503T3 (da) 2007-01-22
CN1155546A (zh) 1997-07-30
CZ291731B6 (cs) 2003-05-14
NO317054B1 (no) 2004-08-02
HUP9603057A2 (en) 1997-05-28
JP4311770B2 (ja) 2009-08-12
SK282168B6 (sk) 2001-11-06
NZ299693A (en) 1997-09-22
AU701624B2 (en) 1999-02-04
EP1375503B1 (en) 2006-12-27
EP0771800A3 (en) 1998-01-28
ES2277014T3 (es) 2007-07-01
SK141496A3 (en) 1997-08-06
US5756532A (en) 1998-05-26
HUP9603057A3 (en) 1998-12-28
IL119565A0 (en) 1997-03-18
US5962465A (en) 1999-10-05
ATE349450T1 (de) 2007-01-15
JPH09249671A (ja) 1997-09-22
HU224841B1 (en) 2006-03-28
EP1375503A1 (en) 2004-01-02
KR970027068A (ko) 1997-06-24
EP0771800A2 (en) 1997-05-07
NO964686L (no) 1997-05-07

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