NO964095D0 - Nye hydroksypyridinoner - Google Patents

Nye hydroksypyridinoner

Info

Publication number
NO964095D0
NO964095D0 NO964095A NO964095A NO964095D0 NO 964095 D0 NO964095 D0 NO 964095D0 NO 964095 A NO964095 A NO 964095A NO 964095 A NO964095 A NO 964095A NO 964095 D0 NO964095 D0 NO 964095D0
Authority
NO
Norway
Prior art keywords
hydroxypyridinones
new
new hydroxypyridinones
Prior art date
Application number
NO964095A
Other languages
English (en)
Other versions
NO964095L (no
Inventor
Paul Zbinden
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO964095D0 publication Critical patent/NO964095D0/no
Publication of NO964095L publication Critical patent/NO964095L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
NO964095A 1995-09-29 1996-09-27 Nye hydroksypyridinoner NO964095L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH275995 1995-09-29

Publications (2)

Publication Number Publication Date
NO964095D0 true NO964095D0 (no) 1996-09-27
NO964095L NO964095L (no) 1997-04-01

Family

ID=4240981

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964095A NO964095L (no) 1995-09-29 1996-09-27 Nye hydroksypyridinoner

Country Status (22)

Country Link
US (1) US5688815A (no)
EP (1) EP0768302B1 (no)
JP (1) JPH09124603A (no)
KR (1) KR970015576A (no)
CN (1) CN1151399A (no)
AR (1) AR005419A1 (no)
AT (1) ATE299135T1 (no)
AU (1) AU6584596A (no)
BR (1) BR9603929A (no)
CA (1) CA2186716A1 (no)
CZ (1) CZ284896A3 (no)
DE (1) DE59611243D1 (no)
ES (1) ES2244967T3 (no)
HU (1) HUP9602681A1 (no)
IL (1) IL119316A (no)
MX (1) MX9604367A (no)
NO (1) NO964095L (no)
NZ (1) NZ299452A (no)
PT (1) PT768302E (no)
SA (1) SA96170399B1 (no)
TR (1) TR199600765A2 (no)
ZA (1) ZA968150B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9711093D0 (en) 1997-05-29 1997-07-23 British Tech Group Novel orally active iron (III) chelators
US6448273B1 (en) 1997-05-29 2002-09-10 Btg International Limited Orally active iron (III) chelators
GB9723078D0 (en) * 1997-10-31 1998-01-07 Cerebrus Ltd Chemical compounds
JPH11147377A (ja) * 1997-11-18 1999-06-02 Teijin Ltd 感熱転写リボン用二軸配向ポリエステルフィルム
US6767741B1 (en) * 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
EP1210410B1 (en) * 1999-08-27 2008-01-16 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
US6846915B2 (en) 2001-08-13 2005-01-25 The Regents Of The University Of California Hydroxypyridonate and hydroxypyrimidinone chelating agents
US6426418B1 (en) 2001-11-02 2002-07-30 Apotex, Inc. Processes for the manufacturing of 3-hydroxy-N,1,6-trialkyl-4-oxo-1,4-dihydropyridine-2-carboxamide
DE60316410T2 (de) 2002-02-05 2008-06-19 Bristol-Myers Squibb Co. N-substituierte 3-hydroxy-4-pyridinone und diese enthaltende pharmazeutika
US20050008699A1 (en) * 2003-07-11 2005-01-13 Fred Wehling Effervescent glucosamine composition
NZ529657A (en) * 2003-11-20 2004-07-30 Apotex Inc Iron chelating cycloalkyl derivatives of 3-hydroxy-4-pyridinones
CA2488034C (en) * 2004-11-19 2009-10-06 Apotex Inc. Process for the manufacture of 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1,4-dihydropyridine-2-carboxamide and its related analogues
GB0506677D0 (en) * 2005-04-01 2005-05-11 Btg Int Ltd Iron modulators
PT2660239T (pt) 2008-07-25 2017-02-24 Shionogi & Co Compostos químicos como intermediários sintéticos
US20100041653A1 (en) * 2008-08-15 2010-02-18 Burnham Institute For Medical Research Composition and methods for the design and development of metallo-enzyme inhibitors
CN102245182B (zh) 2008-12-11 2014-07-23 盐野义制药株式会社 氨基甲酰基吡啶酮hiv整合酶抑制剂和中间体的合成
CN106986823A (zh) * 2008-12-11 2017-07-28 盐野义制药株式会社 氨甲酰基吡啶酮hiv整合酶抑制剂的方法和中间体
TWI518084B (zh) 2009-03-26 2016-01-21 鹽野義製藥股份有限公司 哌喃酮與吡啶酮衍生物之製造方法
CN101906069B (zh) * 2009-06-02 2012-12-12 首都医科大学 (s)-2-取代-(3'-乙酰基-2'-吡啶酮-1'-基)乙酸及其制备方法和应用
SG177462A1 (en) * 2009-07-03 2012-02-28 Apotex Technologies Inc Fluorinated derivatives of 3-hydroxypyridin-4-ones
TWI582097B (zh) 2010-03-23 2017-05-11 Viiv醫療保健公司 製備胺甲醯吡啶酮衍生物及中間體之方法
JP5901076B2 (ja) * 2010-07-27 2016-04-06 クラリアント・ファイナンス・(ビーブイアイ)・リミテッド 過酸化水素又は過酸化水素遊離物質を安定化するためのヒドロキシピリドン類又はそれらの塩の使用
CN105017138A (zh) * 2015-08-06 2015-11-04 中国科学技术大学 一种乙二醇化3-羟基吡啶-4-酮类化合物及其制备方法和用途
CN110790737B (zh) * 2019-11-07 2022-07-22 河南中烟工业有限责任公司 一种2,3-二氢-3,5-二羟基-6-乙基-4h-吡喃-4-酮的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518098A1 (de) * 1963-09-19 1969-04-10 Pfizer & Co C Verfahren zur Herstellung von Pyromekonsaeurederivaten
GB2118176B (en) * 1982-03-24 1985-12-04 Nat Res Dev Pharmaceutical compositions
GB8308054D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
US4908371A (en) * 1987-11-10 1990-03-13 Ciba-Geigy Corporation Esterified hydroxy dihydropyridinones for treating diseases associated with trivalent metal ion overload
EP0325559B1 (de) * 1988-01-20 1993-12-15 Ciba-Geigy Ag Verfahren zur Herstellung von Komplexverbindungen
WO1989009211A1 (en) * 1988-03-31 1989-10-05 The Royal Free Hospital School Of Medicine Process for producing pyrid-4-ones
US4980371A (en) * 1988-12-21 1990-12-25 Merrell Dow Pharmaceuticals Antiretroviral furan ketones
US5112968A (en) * 1989-07-28 1992-05-12 E. R. Squibb & Sons, Inc. Monobactam hydrazide derivatives
GB9100465D0 (en) * 1991-01-09 1991-02-20 Hider Robert C Pharmaceutical compositions
GB9209078D0 (en) * 1992-04-27 1992-06-10 Hider Robert C Pharmaceutical compositions
EP0579221A1 (en) * 1992-07-17 1994-01-19 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
GB9216506D0 (en) * 1992-08-04 1992-09-16 Rice Evans Catherine A Improvements in or relating to the treatment of sickle cell disease
GB9217099D0 (en) * 1992-08-12 1992-09-23 British Tech Group Pharmaceutical compositions
US5789426A (en) * 1995-01-20 1998-08-04 Cornell Research Foundation, Inc. Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation

Also Published As

Publication number Publication date
ES2244967T3 (es) 2005-12-16
ZA968150B (en) 1997-04-01
IL119316A (en) 2000-08-13
HUP9602681A1 (en) 1997-09-29
TR199600765A2 (tr) 1997-05-21
BR9603929A (pt) 1998-06-09
US5688815A (en) 1997-11-18
KR970015576A (ko) 1997-04-28
EP0768302B1 (de) 2005-07-06
SA96170399B1 (ar) 2007-01-20
PT768302E (pt) 2005-11-30
AR005419A1 (es) 1999-06-23
CA2186716A1 (en) 1997-03-30
ATE299135T1 (de) 2005-07-15
DE59611243D1 (de) 2005-08-11
NZ299452A (en) 1998-06-26
HU9602681D0 (en) 1996-11-28
JPH09124603A (ja) 1997-05-13
EP0768302A2 (de) 1997-04-16
CN1151399A (zh) 1997-06-11
MX9604367A (es) 1997-10-31
CZ284896A3 (en) 1997-04-16
AU6584596A (en) 1997-04-10
NO964095L (no) 1997-04-01
EP0768302A3 (de) 1998-02-25
IL119316A0 (en) 1996-12-05

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