NO955197D0 - Nye karbosykliske nucleoside midler som er anvendbare som inhibitorer av pro-inflammatoriske cytokiner - Google Patents

Nye karbosykliske nucleoside midler som er anvendbare som inhibitorer av pro-inflammatoriske cytokiner

Info

Publication number: NO955197D0
Authority: NO; Norway
Prior art keywords: pro; inhibitors; alkyl; compounds; inflammatory cytokines
Prior art date: 1993-06-21

Application number

NO955197A

Other languages

English (en)

Other versions

NO955197L (no

NO312836B1 (no

Inventor

Iii Carl Keith Edwards

David Roger Borcherding

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-21

Filing date

1995-12-20

Publication date

1995-12-20

1995-12-20 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1995-12-20 Publication of NO955197D0 publication Critical patent/NO955197D0/no

1996-02-16 Publication of NO955197L publication Critical patent/NO955197L/no

2002-07-08 Publication of NO312836B1 publication Critical patent/NO312836B1/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

NO19955197A 1993-06-21 1995-12-20 Forbindelser anvendelige som selektive inhibitorer av pro- inflammatoriske cytokiner og farmasöytisk preparat inneholdendenevnte forbindelser NO312836B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8024993A	1993-06-21	1993-06-21
PCT/US1994/005916 WO1995000514A1 (en)	1993-06-21	1994-05-25	Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines

Publications (3)

Publication Number	Publication Date
NO955197D0 true NO955197D0 (no)	1995-12-20
NO955197L NO955197L (no)	1996-02-16
NO312836B1 NO312836B1 (no)	2002-07-08

Family

ID=22156170

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19955197A NO312836B1 (no)	1993-06-21	1995-12-20	Forbindelser anvendelige som selektive inhibitorer av pro- inflammatoriske cytokiner og farmasöytisk preparat inneholdendenevnte forbindelser

Country Status (20)

Country	Link
US (1)	US6541482B2 (no)
EP (1)	EP0705263B1 (no)
JP (1)	JP3479077B2 (no)
KR (1)	KR100337720B1 (no)
CN (1)	CN1041631C (no)
AT (1)	ATE151423T1 (no)
AU (1)	AU677851B2 (no)
CA (1)	CA2165779C (no)
DE (1)	DE69402548T2 (no)
DK (1)	DK0705263T3 (no)
ES (1)	ES2103131T3 (no)
FI (1)	FI956142A0 (no)
GR (1)	GR3023373T3 (no)
HU (1)	HUT73412A (no)
IL (1)	IL110041A0 (no)
NO (1)	NO312836B1 (no)
NZ (1)	NZ267322A (no)
TW (1)	TW356471B (no)
WO (1)	WO1995000514A1 (no)
ZA (1)	ZA944256B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0111497D0 (en) *	2001-05-11	2001-07-04	Medical Res Council	Therapeutic methods
GB0114286D0 (en) *	2001-06-12	2001-08-01	Hoffmann La Roche	Nucleoside Derivatives
WO2004056868A2 (en) *	2002-12-19	2004-07-08	Endocube Sas	Nf-hev compositions and methods of use
US7196093B2 (en)	2003-04-09	2007-03-27	General Atomics	Reversible inhibitors of SAH hydrolase and uses thereof
US7868011B2 (en)	2003-04-09	2011-01-11	General Atomics	Use of reversible inhibitors of S-adenosyl-L-homocysteine hydrolase for treating lupus
US7517887B2 (en)	2003-04-09	2009-04-14	General Atomics	Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof
US11033821B2 (en)	2003-09-02	2021-06-15	Jeffrey D. Mullen	Systems and methods for location based games and employment of the same on location enabled devices
CA2569016C (en) *	2004-06-02	2012-11-27	Takeda Pharmaceutical Company Limited	Fused heterocyclic compound

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN164556B (no)	1986-03-06	1989-04-08	Takeda Chemical Industries Ltd
US4931559A (en)	1988-01-20	1990-06-05	Regents Of The University Of Minnesota	Optically-active isomers of dideoxycarbocyclic nucleosides
US4916224A (en)	1988-01-20	1990-04-10	Regents Of The University Of Minnesota	Dideoxycarbocyclic nucleosides
GB8815265D0 (en)	1988-06-27	1988-08-03	Wellcome Found	Therapeutic nucleosides
AU642526B2 (en)	1990-09-14	1993-10-21	Marion Merrell Dow Inc.	Method of immunosuppression using cyclopentenyl substituted nucleoside analogs and compositions thereof
AU647822B2 (en) *	1990-09-14	1994-03-31	Marion Merrell Dow Inc.	Novel carbocyclic adenosine analogs useful as immunosuppressants
US5332814A (en) *	1991-11-12	1994-07-26	Ciba-Geigy Corporation	Process for the preparation of carbacyclic nucleosides, and intermediates
AU658698B2 (en)	1991-12-06	1995-04-27	Aventis Pharmaceuticals Inc.	Novel trans cyclopentanyl purine analogs useful as immunosuppressants
GB9204015D0 (en) *	1992-02-25	1992-04-08	Wellcome Found	Therapeutic nucleosides
SK284810B6 (sk) *	1997-05-13	2005-12-01	Lonza Ag	Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purín-9-yl)-2-cyklopentén-1-metanolu
JPH11255768A (ja) *	1998-03-09	1999-09-21	Ajinomoto Co Inc	抗ウイルス剤の製造方法

1994
- 1994-05-25 DE DE69402548T patent/DE69402548T2/de not_active Expired - Lifetime
- 1994-05-25 JP JP50282295A patent/JP3479077B2/ja not_active Expired - Lifetime
- 1994-05-25 HU HU9503689A patent/HUT73412A/hu unknown
- 1994-05-25 WO PCT/US1994/005916 patent/WO1995000514A1/en active IP Right Grant
- 1994-05-25 AT AT94918130T patent/ATE151423T1/de not_active IP Right Cessation
- 1994-05-25 CA CA002165779A patent/CA2165779C/en not_active Expired - Fee Related
- 1994-05-25 ES ES94918130T patent/ES2103131T3/es not_active Expired - Lifetime
- 1994-05-25 KR KR1019950705826A patent/KR100337720B1/ko not_active IP Right Cessation
- 1994-05-25 NZ NZ267322A patent/NZ267322A/en unknown
- 1994-05-25 EP EP94918130A patent/EP0705263B1/en not_active Expired - Lifetime
- 1994-05-25 AU AU69583/94A patent/AU677851B2/en not_active Ceased
- 1994-05-25 DK DK94918130.9T patent/DK0705263T3/da active
- 1994-05-25 CN CN94192526A patent/CN1041631C/zh not_active Expired - Fee Related
- 1994-06-15 ZA ZA944256A patent/ZA944256B/xx unknown
- 1994-06-16 TW TW083105476A patent/TW356471B/zh active
- 1994-06-17 IL IL11004194A patent/IL110041A0/xx unknown
1995
- 1995-02-03 US US08/383,339 patent/US6541482B2/en not_active Expired - Fee Related
- 1995-12-20 FI FI956142A patent/FI956142A0/fi not_active Application Discontinuation
- 1995-12-20 NO NO19955197A patent/NO312836B1/no unknown
1997
- 1997-05-09 GR GR970401026T patent/GR3023373T3/el unknown

Also Published As

Publication number	Publication date
WO1995000514A1 (en)	1995-01-05
JPH08511558A (ja)	1996-12-03
JP3479077B2 (ja)	2003-12-15
US6541482B2 (en)	2003-04-01
GR3023373T3 (en)	1997-08-29
CN1041631C (zh)	1999-01-13
AU6958394A (en)	1995-01-17
ATE151423T1 (de)	1997-04-15
NZ267322A (en)	1997-09-22
FI956142A (fi)	1995-12-20
NO955197L (no)	1996-02-16
KR100337720B1 (ko)	2002-11-02
CA2165779A1 (en)	1995-01-05
AU677851B2 (en)	1997-05-08
CA2165779C (en)	1998-06-16
DE69402548T2 (de)	1997-07-17
DE69402548D1 (de)	1997-05-15
ES2103131T3 (es)	1997-08-16
IL110041A0 (en)	1994-10-07
US20020004508A1 (en)	2002-01-10
KR960703122A (ko)	1996-06-19
HUT73412A (en)	1996-07-29
HU9503689D0 (en)	1996-02-28
ZA944256B (en)	1995-02-08
NO312836B1 (no)	2002-07-08
EP0705263A1 (en)	1996-04-10
TW356471B (en)	1999-04-21
DK0705263T3 (da)	1997-05-05
FI956142A0 (fi)	1995-12-20
CN1125946A (zh)	1996-07-03
EP0705263B1 (en)	1997-04-09

Publication	Publication Date	Title
HUP0101031A2 (hu)	2001-08-28	Biciklo[2.2.1]heptán-származékok és rokon vegyületek
TW370529B (en)	1999-09-21	Pyrazolopyrimidines
HUP0203657A2 (hu)	2003-03-28	Heterociklusos vegyületek és eljárások a szívgyengeség és más rendellenességek kezelésére
NO20053340L (no)	2005-09-12	Substituerte dihydropyrano-indol-3,4-dion-derivater som inhibitorer for plasmigogenaktivator-1 (CPAI-1).
ES2188280T3 (es)	2003-06-16	Acetales heteroaril-ciclicos.
NO306237B1 (no)	1999-10-11	Anvendelse av xantinderivater som antidepressive midler
HUP0004221A2 (hu)	2001-04-28	O-Helyettesített hidroxi-kumaranon-származékok, alkalmazásuk tumor- és metasztázis-ellenes gyógyszerkészítmények előállítására és a gyógyszerkészítmények
HUP0201722A2 (hu)	2003-07-28	Gyógyászati készítmények alkoholizmus és alkoholfüggőség kezelésére
DK0686142T3 (da)	1999-08-30	Polyaminderivater som radioprotektive midler
YU46787B (sh)	1994-06-10	Derivati heteroaril 3-okso-propan-nitrila i postupak za njihovo dobijanje
KR910007883A (ko)	1991-05-30	퀴놀린 유도체, 그의 제조방법 및 용도
NO955197D0 (no)	1995-12-20	Nye karbosykliske nucleoside midler som er anvendbare som inhibitorer av pro-inflammatoriske cytokiner
HUP0303449A2 (hu)	2004-01-28	Szubsztituált benzofurán-2-karboxamid-származékok
NO964698L (no)	1996-11-06	Bicykliske aminderivater som inhibitorer av nitrogenoksid-syntetase
NO912298L (no)	1991-12-16	Fremgangsmaate for fremstilling av terapeutisk aktive 1,3-dioksanderivater.
HUP0001010A2 (hu)	2001-04-28	Benzimidazol-származékok és ezeket a vegyületeket tartalmazó gyógyszerkészítmények
AU4713797A (en)	1998-05-15	Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents
UA26459C2 (uk)	1999-08-30	Іhгібітор впливу амілоїдhих білків
HUP0000783A2 (hu)	2001-04-28	N-(piridinil-amino)-izoindolinok és származékaik, eljárás előállításukra, e vegyületeket tartalmazó gyógyszerkészítmények és alkalmazásuk
MY131365A (en)	2007-08-30	Carbamic acid derivatives
DK0475413T3 (da)	1996-07-15	Carbocycliske nukleosidanaloge, der kan anvendes som immunsuppressorer
RU94031211A (ru)	1996-03-20	Производные изатина, способ их получения и фармацевтическая композиция на их основе