NO943688L - Fremgangsmåte for fremstilling av 4-pyridyl- og 4-piperidinylimidazoler som er nyttige som mellomprodukter for syntese av histaminreseptorantagonister - Google Patents

Fremgangsmåte for fremstilling av 4-pyridyl- og 4-piperidinylimidazoler som er nyttige som mellomprodukter for syntese av histaminreseptorantagonister

Info

Publication number
NO943688L
NO943688L NO943688A NO943688A NO943688L NO 943688 L NO943688 L NO 943688L NO 943688 A NO943688 A NO 943688A NO 943688 A NO943688 A NO 943688A NO 943688 L NO943688 L NO 943688L
Authority
NO
Norway
Prior art keywords
receptor antagonists
preparation
intermediates
useful
piperidinylimidazoles
Prior art date
Application number
NO943688A
Other languages
English (en)
Other versions
NO943688D0 (no
Inventor
Graham J Durant
Amin M Khan
Original Assignee
Univ Toledo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toledo filed Critical Univ Toledo
Publication of NO943688D0 publication Critical patent/NO943688D0/no
Publication of NO943688L publication Critical patent/NO943688L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Ny fremgangsmåte for fremstilling av sterktvirkende histaminreseptorantagonister av formelen: R4¿N N-Z (D spesielt histamin H3-reseptorantagonlster. Det er også beskrevet en ny fremgangsmåte for fremstilling av mellomprodukter (II) *_ ¿¿ (II) og (III) R1 X NH (ni) som er nyttige i fremstillingen av histaminreseptor- antagonister, spesielt H3-reseptorantagonister.
NO943688A 1992-04-01 1994-10-03 Fremgangsmåte for fremstilling av 4-pyridyl- og 4-piperidinylimidazoler som er nyttige som mellomprodukter for syntese av histaminreseptorantagonister NO943688L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/862,658 US5380858A (en) 1992-04-01 1992-04-01 Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists
PCT/US1993/003105 WO1993020062A1 (en) 1992-04-01 1993-03-31 Process for the preparation of 4-pyridyl- and 4-piperidinylimidazoles useful as intermediates for the synthesis of histamine receptor antagonists

Publications (2)

Publication Number Publication Date
NO943688D0 NO943688D0 (no) 1994-10-03
NO943688L true NO943688L (no) 1994-11-25

Family

ID=25338980

Family Applications (1)

Application Number Title Priority Date Filing Date
NO943688A NO943688L (no) 1992-04-01 1994-10-03 Fremgangsmåte for fremstilling av 4-pyridyl- og 4-piperidinylimidazoler som er nyttige som mellomprodukter for syntese av histaminreseptorantagonister

Country Status (13)

Country Link
US (2) US5380858A (no)
EP (1) EP0633883A1 (no)
JP (1) JPH07509220A (no)
KR (1) KR950700899A (no)
AU (1) AU3944693A (no)
BR (1) BR9306191A (no)
CA (1) CA2133460A1 (no)
FI (1) FI944606A (no)
HU (1) HU9402826D0 (no)
NO (1) NO943688L (no)
RU (1) RU94045838A (no)
SK (1) SK118894A3 (no)
WO (1) WO1993020062A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817823A (en) * 1997-04-17 1998-10-06 Sepracor Inc. Method for synthesizing 2-substituted imidazoles
US6887870B1 (en) * 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
EP1707203A1 (en) 2005-04-01 2006-10-04 Bioprojet Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands
EP1717235A3 (en) 2005-04-29 2007-02-28 Bioprojet Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands
EP1717233A1 (en) * 2005-04-29 2006-11-02 Bioprojet Histamine H3-receptor ligands and their therapeutic application
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2579596B1 (fr) * 1985-03-26 1987-11-20 Inst Nat Sante Rech Med (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique
FR2671083B1 (fr) * 1990-12-31 1994-12-23 Inst Nat Sante Rech Med Nouvelles 4-(4-imidazolyl) piperidines substituees en 1, leur preparation ainsi que leurs applications therapeutiques.
FR2674855B1 (fr) * 1991-04-03 1994-01-14 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
FI944606A0 (fi) 1994-10-03
EP0633883A1 (en) 1995-01-18
JPH07509220A (ja) 1995-10-12
FI944606A (fi) 1994-11-30
RU94045838A (ru) 1996-08-10
US5380858A (en) 1995-01-10
HU9402826D0 (en) 1994-12-28
SK118894A3 (en) 1995-07-11
US5663350A (en) 1997-09-02
WO1993020062A1 (en) 1993-10-14
NO943688D0 (no) 1994-10-03
KR950700899A (ko) 1995-02-20
CA2133460A1 (en) 1993-10-14
AU3944693A (en) 1993-11-08
BR9306191A (pt) 1998-06-30

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