FI944606A - Menetelmä 4-pyridyyli- ja 4-piperidinyyli-imidatsolien valmistamiseksi, jotka ovat käyttökelpoisia histamiinireseptoriantagonistien synteesin välituotteina - Google Patents

Menetelmä 4-pyridyyli- ja 4-piperidinyyli-imidatsolien valmistamiseksi, jotka ovat käyttökelpoisia histamiinireseptoriantagonistien synteesin välituotteina Download PDF

Info

Publication number: FI944606A
Authority: FI; Finland
Prior art keywords: piperidinylimidazoles; pyridyl; intermediates; synthesis; useful
Prior art date: 1992-04-01

Application number

FI944606A

Other languages

English (en)

Swedish (sv)

Other versions

FI944606A0 (fi

Inventor

Graham J Durant

Amin M Khan

Original Assignee

Univ Toledo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-01

Filing date

1994-10-03

Publication date

1994-11-30

1994-10-03 Application filed by Univ Toledo filed Critical Univ Toledo

1994-10-03 Publication of FI944606A0 publication Critical patent/FI944606A0/fi

1994-11-30 Publication of FI944606A publication Critical patent/FI944606A/fi

Links

BSTAWYYHYJYBIZ-UHFFFAOYSA-N 1-(1h-imidazol-5-yl)piperidine Chemical class C1CCCCN1C1=CNC=N1 BSTAWYYHYJYBIZ-UHFFFAOYSA-N 0.000 title 1
125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 title 1
229940122236 Histamine receptor antagonist Drugs 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
238000000034 method Methods 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

FI944606A 1992-04-01 1994-10-03 Menetelmä 4-pyridyyli- ja 4-piperidinyyli-imidatsolien valmistamiseksi, jotka ovat käyttökelpoisia histamiinireseptoriantagonistien synteesin välituotteina FI944606A (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/862,658 US5380858A (en)	1992-04-01	1992-04-01	Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists
PCT/US1993/003105 WO1993020062A1 (en)	1992-04-01	1993-03-31	Process for the preparation of 4-pyridyl- and 4-piperidinylimidazoles useful as intermediates for the synthesis of histamine receptor antagonists

Publications (2)

Publication Number	Publication Date
FI944606A0 FI944606A0 (fi)	1994-10-03
FI944606A true FI944606A (fi)	1994-11-30

Family

ID=25338980

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI944606A FI944606A (fi)	1992-04-01	1994-10-03	Menetelmä 4-pyridyyli- ja 4-piperidinyyli-imidatsolien valmistamiseksi, jotka ovat käyttökelpoisia histamiinireseptoriantagonistien synteesin välituotteina

Country Status (13)

Country	Link
US (2)	US5380858A (fi)
EP (1)	EP0633883A1 (fi)
JP (1)	JPH07509220A (fi)
KR (1)	KR950700899A (fi)
AU (1)	AU3944693A (fi)
BR (1)	BR9306191A (fi)
CA (1)	CA2133460A1 (fi)
FI (1)	FI944606A (fi)
HU (1)	HU9402826D0 (fi)
NO (1)	NO943688L (fi)
RU (1)	RU94045838A (fi)
SK (1)	SK118894A3 (fi)
WO (1)	WO1993020062A1 (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5817823A (en) *	1997-04-17	1998-10-06	Sepracor Inc.	Method for synthesizing 2-substituted imidazoles
US6887870B1 (en) *	1999-10-12	2005-05-03	Bristol-Myers Squibb Company	Heterocyclic sodium/proton exchange inhibitors and method
EP1707203A1 (en)	2005-04-01	2006-10-04	Bioprojet	Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands
EP1717235A3 (en)	2005-04-29	2007-02-28	Bioprojet	Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands
EP1717233A1 (en) *	2005-04-29	2006-11-02	Bioprojet	Histamine H3-receptor ligands and their therapeutic application
WO2013151982A1 (en)	2012-04-03	2013-10-10	Arena Pharmaceuticals, Inc.	Methods and compounds useful in treating pruritus, and methods for identifying such compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2579596B1 (fr) *	1985-03-26	1987-11-20	Inst Nat Sante Rech Med	(imidazolyl-4) piperidines, leur preparation et leur application en therapeutique
FR2671083B1 (fr) *	1990-12-31	1994-12-23	Inst Nat Sante Rech Med	Nouvelles 4-(4-imidazolyl) piperidines substituees en 1, leur preparation ainsi que leurs applications therapeutiques.
FR2674855B1 (fr) *	1991-04-03	1994-01-14	Synthelabo	Derives de piperidine, leur preparation et leur application en therapeutique.

1992
- 1992-04-01 US US07/862,658 patent/US5380858A/en not_active Expired - Fee Related
1993
- 1993-03-31 CA CA002133460A patent/CA2133460A1/en not_active Abandoned
- 1993-03-31 SK SK1188-94A patent/SK118894A3/sk unknown
- 1993-03-31 WO PCT/US1993/003105 patent/WO1993020062A1/en not_active Application Discontinuation
- 1993-03-31 BR BR9306191A patent/BR9306191A/pt not_active Application Discontinuation
- 1993-03-31 EP EP93908725A patent/EP0633883A1/en not_active Withdrawn
- 1993-03-31 HU HU9402826A patent/HU9402826D0/hu unknown
- 1993-03-31 RU RU94045838/04A patent/RU94045838A/ru unknown
- 1993-03-31 JP JP5517716A patent/JPH07509220A/ja active Pending
- 1993-03-31 AU AU39446/93A patent/AU3944693A/en not_active Abandoned
1994
- 1994-06-02 US US08/252,810 patent/US5663350A/en not_active Expired - Fee Related
- 1994-09-30 KR KR1019940703409A patent/KR950700899A/ko not_active Application Discontinuation
- 1994-10-03 FI FI944606A patent/FI944606A/fi not_active Application Discontinuation
- 1994-10-03 NO NO943688A patent/NO943688L/no unknown

Also Published As

Publication number	Publication date
FI944606A0 (fi)	1994-10-03
EP0633883A1 (en)	1995-01-18
JPH07509220A (ja)	1995-10-12
RU94045838A (ru)	1996-08-10
US5380858A (en)	1995-01-10
HU9402826D0 (en)	1994-12-28
SK118894A3 (en)	1995-07-11
US5663350A (en)	1997-09-02
WO1993020062A1 (en)	1993-10-14
NO943688D0 (no)	1994-10-03
KR950700899A (ko)	1995-02-20
CA2133460A1 (en)	1993-10-14
AU3944693A (en)	1993-11-08
BR9306191A (pt)	1998-06-30
NO943688L (no)	1994-11-25

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Legal Events

Date	Code	Title	Description
1995-08-09	FD	Application lapsed