NO924479L - Nye aminoalkanfosfinsyrer og deres salter - Google Patents

Nye aminoalkanfosfinsyrer og deres salter

Info

Publication number: NO924479L
Authority: NO; Norway
Prior art keywords: ethyl; dichlorophenyl; dimethoxyphenyl; hydrogen; chloro
Prior art date: 1991-11-21

Application number

NO92924479A

Other languages

English (en)

Norwegian (no)

Other versions

NO924479D0 (no

Inventor

Stuart John Mickel

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-21

Filing date

1992-11-20

Publication date

1993-05-24

1992-11-20 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1992-11-20 Publication of NO924479D0 publication Critical patent/NO924479D0/no

1993-05-24 Publication of NO924479L publication Critical patent/NO924479L/no

Links

150000003839 salts Chemical class 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
150000007513 acids Chemical class 0.000 title 1
-1 1- (4-chlorophenyl) ethyl Chemical group 0.000 abstract 45
229910052739 hydrogen Inorganic materials 0.000 abstract 10
239000001257 hydrogen Substances 0.000 abstract 10
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 6
150000002431 hydrogen Chemical class 0.000 abstract 4
125000006512 3,4-dichlorobenzyl group Chemical group [H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])* 0.000 abstract 2
239000005557 antagonist Substances 0.000 abstract 2
125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 2
125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 2
125000004188 dichlorophenyl group Chemical group 0.000 abstract 2
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000006185 3,4-dimethyl benzyl group Chemical group [H]C1=C(C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])* 0.000 abstract 1
125000006283 4-chlorobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])* 0.000 abstract 1
125000004217 4-methoxybenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])* 0.000 abstract 1
125000006181 4-methyl benzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])* 0.000 abstract 1
RRXSYZFVDIRTFB-UHFFFAOYSA-N C[CH]C1=CC=C(OC)C=C1 Chemical group C[CH]C1=CC=C(OC)C=C1 RRXSYZFVDIRTFB-UHFFFAOYSA-N 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/60—Quinoline or hydrogenated quinoline ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Air Bags (AREA)

NO92924479A 1991-11-21 1992-11-20 Nye aminoalkanfosfinsyrer og deres salter NO924479L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH340491		1991-11-21

Publications (2)

Publication Number	Publication Date
NO924479D0 NO924479D0 (no)	1992-11-20
NO924479L true NO924479L (no)	1993-05-24

Family

ID=4255259

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
NO92924479A NO924479L (no)	1991-11-21	1992-11-20	Nye aminoalkanfosfinsyrer og deres salter
NO974116A NO974116D0 (no)	1991-11-21	1997-09-08	Nye aminoalkanfosfinsyrer og deres salter
NO974115A NO974115D0 (no)	1991-11-21	1997-09-08	Nye aminoalkanfosfinsyrer og deres salter
NO974117A NO974117D0 (no)	1991-11-21	1997-09-08	Nye aminoalkanfosfinsyrer og deres salter

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
NO974116A NO974116D0 (no)	1991-11-21	1997-09-08	Nye aminoalkanfosfinsyrer og deres salter
NO974115A NO974115D0 (no)	1991-11-21	1997-09-08	Nye aminoalkanfosfinsyrer og deres salter
NO974117A NO974117D0 (no)	1991-11-21	1997-09-08	Nye aminoalkanfosfinsyrer og deres salter

Country Status (14)

Country	Link
US (2)	US5376684A (ja)
EP (2)	EP0767174A1 (ja)
JP (1)	JPH05247069A (ja)
KR (1)	KR930010047A (ja)
AU (2)	AU662938B2 (ja)
CA (1)	CA2083307A1 (ja)
FI (1)	FI925243A (ja)
IL (1)	IL103808A0 (ja)
MX (1)	MX9206702A (ja)
NO (4)	NO924479L (ja)
NZ (1)	NZ245185A (ja)
PH (1)	PH30097A (ja)
TW (1)	TW213466B (ja)
ZA (1)	ZA928979B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL114631A (en) *	1990-06-22	1998-12-06	Novartis Ag	Anti-epileptic preparations containing antagonists of BABAG
EP0767174A1 (de) *	1991-11-21	1997-04-09	Ciba-Geigy Ag	Neue Aminoalkanphosphinsäuren und ihre Salze
AU662404B2 (en) *	1992-05-08	1995-08-31	Novartis Ag	Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids
WO1997011953A1 (en) *	1995-09-28	1997-04-03	Novartis Ag	Novel hydroxylated and alkoxylated n- and/or p-aralkylphosphinic acid derivatives
DE69827635T2 (de) *	1997-06-23	2006-02-02	Neuro Therapeutics Ltd., Toorak	Gaba-c-rezeptor-antagonisten zur stimulation des erinnerungsvermögens
DE10014127A1 (de) *	2000-03-22	2001-10-18	Hassan Jomaa	Verwendung von phosphororganischen Verbindungen zur Behandlung von Infektionen
US6462084B1 (en)	2001-05-14	2002-10-08	Brookhaven Science Associates, Llc	Treatment for obsessive-compulsive disorder (OCD) and OCD-related disorders using GVG
AR045794A1 (es) *	2003-09-23	2005-11-16	Aventis Pharma Inc	Procedimiento para preparar derivados de acido 3- amino-2- hidroxipropilfosfinico
GB0327186D0 (en) *	2003-11-21	2003-12-24	Novartis Ag	Organic compounds
US7566738B2 (en) *	2004-11-03	2009-07-28	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7494985B2 (en) *	2004-11-03	2009-02-24	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
AR052669A1 (es) *	2005-02-11	2007-03-28	Aventis Pharma Inc	Esteres de acido de acido propano - fosfinico sustituido; composiciones farmaceuticas que los contienen y su uso para el tratamiento de trastornos psiquiatricos.
WO2008033572A1 (en) *	2006-09-15	2008-03-20	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis and use

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2440239A1 (de) *	1974-08-22	1976-03-04	Hoechst Ag	Innere ammoniumsalze von phosphinsaeuren
EP0093081B1 (de) *	1982-04-23	1986-03-19	Ciba-Geigy Ag	Herbizide und pflanzenwuchsregulierende Mittel
US4536355A (en) *	1982-10-08	1985-08-20	Zoecon Corporation	Phenoxyphenylaminoalkylphosphinates useful in weed control
US5243062A (en) *	1984-10-12	1993-09-07	Ciba-Geigy Corporation	Substituted propane-phosphonous acid compounds
GB8425872D0 (en) *	1984-10-12	1984-11-21	Ciba Geigy Ag	Chemical compounds
DK704488D0 (da) *	1988-12-19	1988-12-19	Novo Industri As	Nye n-substituerede azaheterocykliske carboxylsyrer
US5300679A (en) *	1987-12-04	1994-04-05	Ciba-Geigy Corporation	Substituted propane-phosphinic acid compounds
US5190933A (en) *	1987-12-04	1993-03-02	Ciba-Geigy Corporation	Substituted propane-phosphinic acid compounds
GB8728483D0 (en) *	1987-12-04	1988-01-13	Ciba Geigy Ag	Chemical compounds
DK270488D0 (da) *	1988-05-18	1988-05-18	Novo Industri As	Hidtil ukendte o-substituerede ketoximer
GB8820266D0 (en) *	1988-08-26	1988-09-28	Smith Kline French Lab	Compounds
US5281747A (en) *	1989-05-13	1994-01-25	Ciba-Geigy Corporation	Substituted aminoalkylphosphinic acids
GB8911017D0 (en) *	1989-05-13	1989-06-28	Ciba Geigy Ag	Substituted aminoalkylphosphinic acids
GB8912814D0 (en) *	1989-06-03	1989-07-19	Ciba Geigy Ag	P-substituted propane-phospinic acid compounds
US5190934A (en) *	1989-06-03	1993-03-02	Ciba-Geigy Corporation	P-subsituted propane-phosphinic acid compounds
IL114631A (en) *	1990-06-22	1998-12-06	Novartis Ag	Anti-epileptic preparations containing antagonists of BABAG
EP0767174A1 (de) *	1991-11-21	1997-04-09	Ciba-Geigy Ag	Neue Aminoalkanphosphinsäuren und ihre Salze
AU662404B2 (en) *	1992-05-08	1995-08-31	Novartis Ag	Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids

1992
- 1992-11-12 EP EP96118735A patent/EP0767174A1/de not_active Withdrawn
- 1992-11-12 EP EP19920810879 patent/EP0543780A3/de not_active Ceased
- 1992-11-18 FI FI925243A patent/FI925243A/fi not_active Application Discontinuation
- 1992-11-19 IL IL103808A patent/IL103808A0/xx unknown
- 1992-11-19 CA CA002083307A patent/CA2083307A1/en not_active Abandoned
- 1992-11-19 US US07/979,513 patent/US5376684A/en not_active Expired - Fee Related
- 1992-11-19 JP JP4310082A patent/JPH05247069A/ja active Pending
- 1992-11-19 NZ NZ245185A patent/NZ245185A/en unknown
- 1992-11-19 TW TW081109255A patent/TW213466B/zh active
- 1992-11-19 MX MX9206702A patent/MX9206702A/es not_active Application Discontinuation
- 1992-11-19 AU AU28504/92A patent/AU662938B2/en not_active Ceased
- 1992-11-20 PH PH45301A patent/PH30097A/en unknown
- 1992-11-20 ZA ZA928979A patent/ZA928979B/xx unknown
- 1992-11-20 NO NO92924479A patent/NO924479L/no unknown
- 1992-11-21 KR KR1019920021950A patent/KR930010047A/ko not_active Application Discontinuation
1994
- 1994-09-16 US US08/308,040 patent/US5500418A/en not_active Expired - Fee Related
1995
- 1995-12-14 AU AU40456/95A patent/AU4045695A/en not_active Abandoned
1997
- 1997-09-08 NO NO974116A patent/NO974116D0/no unknown
- 1997-09-08 NO NO974115A patent/NO974115D0/no unknown
- 1997-09-08 NO NO974117A patent/NO974117D0/no unknown

Also Published As

Publication number	Publication date
CA2083307A1 (en)	1993-05-22
AU662938B2 (en)	1995-09-21
US5376684A (en)	1994-12-27
PH30097A (en)	1996-12-27
NO974117L (no)	1993-05-24
FI925243A (fi)	1993-05-22
MX9206702A (es)	1994-06-30
TW213466B (ja)	1993-09-21
NO974116D0 (no)	1997-09-08
KR930010047A (ko)	1993-06-21
NZ245185A (en)	1995-04-27
ZA928979B (en)	1994-04-15
NO974115L (no)	1993-05-24
NO924479D0 (no)	1992-11-20
JPH05247069A (ja)	1993-09-24
US5500418A (en)	1996-03-19
NO974115D0 (no)	1997-09-08
AU4045695A (en)	1996-04-26
EP0767174A1 (de)	1997-04-09
NO974116L (no)	1993-05-24
FI925243A0 (fi)	1992-11-18
NO974117D0 (no)	1997-09-08
EP0543780A3 (en)	1993-09-01
EP0543780A2 (de)	1993-05-26
IL103808A0 (en)	1993-04-04
AU2850492A (en)	1993-05-27

Publication	Publication Date	Title
NO924479L (no)	1993-05-24	Nye aminoalkanfosfinsyrer og deres salter
US6117881A (en)	2000-09-12	N-cinnamoyl derivatives of (β) carbolines
HU211607A9 (en)	1995-12-28	Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
DE3850742D1 (de)	1994-08-25	Neue 4-Oxobenzotriazine und 4-Oxochinazoline.
HUT48250A (en)	1989-05-29	Process for producing new benzimidazolin-2-oxo-1-carboxylic acid derivatives of 5-ht receptor antagonistic activity and pharmaceutical compositions containing them
FI870347A0 (fi)	1987-01-27	Nya dihydrobensofuran- och kromankarboxiamidderivat, foerfarande foer deras framstaellning och deras anvaendning som neuroleptiska medel.
DK225081A (da)	1981-11-23	Aminopropiophenon-derivater og deres syreadditionssalte fremgangsmaader til deres fremstilling og deres anvendelse som gungicider
US5106867A (en)	1992-04-21	Method of increasing lean meat in edible animals
YU45929B (sh)	1992-09-07	Postupak za dobijanje imidazolilalkilgvanidinskih derivata
JP2005516903A5 (ja)	2005-12-22
RU2003106191A (ru)	2004-07-27	Способ лечения аллергии с использованием замещенных пиразолов
KR880009923A (ko)	1988-10-05	질소함유 헤테로사이클릭 메탄올의 아릴옥시메틸 유도체 및 그의 에테르
NO162821C (no)	1990-02-21	Fremgangsmaate for fremstilling av terapeutisk aktive furo-pyridinderivater.
ATE153016T1 (de)	1997-05-15	In der 3-position durch einen gesättigten oder ungesättigten fettsäurerest substituierte pyrrolidinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel mit thromboxan-a2 inhibierender aktivität
FI67074B (fi)	1984-09-28	Tandvaordsmedel innehaollande n-n-butyl-n-cetyl-6-amino-1-hexanol som plackhaemmande foerening
US4859668A (en)	1989-08-22	Method of inhibiting the growth of melanin-pigmented cells
ATE46147T1 (de)	1989-09-15	4-(nitrophenyl)-tetrahydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
NO913644L (no)	1992-03-18	Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
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NO952200L (no)	1995-08-03	Triazol (pyrrol, Tien eller furan)-azepinderivater med antiallergisk virkning
HUP0501211A2 (en)	2007-09-28	Optical isomers of dihydro-2,3-benzodiazepine derivatives, process for their stereoselective synthesis, their use, pharmaceutical compositions containing them and the intermediates of the synthesis
JPWO2019200232A5 (ja)	2022-04-19
ES461758A1 (es)	1978-05-01	Nuevo procedimiento de obtencion de derivados tiocromanicos.