NO921490L - 1-(pyrido(3,4-b)-1,4-oksazinyl-4-yl)-1h-indoler, mellomprodukter og fremgangsmaate for fremstilling derav samt anvendelse som medikamenter - Google Patents

1-(pyrido(3,4-b)-1,4-oksazinyl-4-yl)-1h-indoler, mellomprodukter og fremgangsmaate for fremstilling derav samt anvendelse som medikamenter

Info

Publication number
NO921490L
NO921490L NO92921490A NO921490A NO921490L NO 921490 L NO921490 L NO 921490L NO 92921490 A NO92921490 A NO 92921490A NO 921490 A NO921490 A NO 921490A NO 921490 L NO921490 L NO 921490L
Authority
NO
Norway
Prior art keywords
loweralkyl
hydrogen
chem
ocsazinyl
indoles
Prior art date
Application number
NO92921490A
Other languages
English (en)
Other versions
NO301765B1 (no
NO921490D0 (no
Inventor
Richard Charles Effland
Larry Davis
Gordon Edward Olsen
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO921490D0 publication Critical patent/NO921490D0/no
Publication of NO921490L publication Critical patent/NO921490L/no
Publication of NO301765B1 publication Critical patent/NO301765B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO921490A 1991-04-15 1992-04-14 1-(pyridol[3,4-b]-1,4-oksazinyl-4-yl)-1H-indoler, farmasöytisk sammensetning, samt anvendelse derav NO301765B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/684,758 US5214038A (en) 1991-04-15 1991-04-15 1-(pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles and intermediates for the preparation thereof

Publications (3)

Publication Number Publication Date
NO921490D0 NO921490D0 (no) 1992-04-14
NO921490L true NO921490L (no) 1992-10-16
NO301765B1 NO301765B1 (no) 1997-12-08

Family

ID=24749434

Family Applications (1)

Application Number Title Priority Date Filing Date
NO921490A NO301765B1 (no) 1991-04-15 1992-04-14 1-(pyridol[3,4-b]-1,4-oksazinyl-4-yl)-1H-indoler, farmasöytisk sammensetning, samt anvendelse derav

Country Status (22)

Country Link
US (3) US5214038A (no)
EP (1) EP0509400B1 (no)
JP (1) JP2608359B2 (no)
KR (1) KR100201509B1 (no)
AT (1) ATE140006T1 (no)
AU (1) AU643135B2 (no)
CA (1) CA2065986C (no)
CZ (1) CZ282054B6 (no)
DE (1) DE69211892T2 (no)
DK (1) DK0509400T3 (no)
ES (1) ES2094840T3 (no)
FI (1) FI97544C (no)
GR (1) GR3020612T3 (no)
HU (1) HUT62588A (no)
IE (1) IE74907B1 (no)
IL (1) IL101589A (no)
NO (1) NO301765B1 (no)
NZ (2) NZ242309A (no)
PL (1) PL168671B1 (no)
RU (1) RU2042680C1 (no)
TW (1) TW211016B (no)
ZA (1) ZA922721B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5360811A (en) * 1990-03-13 1994-11-01 Hoechst-Roussel Pharmaceuticals Incorporated 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents
US5264442A (en) * 1990-08-13 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
GB9225859D0 (en) * 1992-12-11 1993-02-03 Smithkline Beecham Plc Novel treatment
US5356910A (en) * 1993-07-19 1994-10-18 Hoechst-Roussel Pharmaceuticals Inc. Use of N-(pyridinyl)-1H-indol-1-amines for the treatment of obsessive-compulsive disorder
GB0119435D0 (en) * 2001-02-15 2001-10-03 Aventis Pharm Prod Inc Method of treating of demyelinating diseases or conditions
EP1424325A4 (en) * 2001-09-07 2005-12-21 Ono Pharmaceutical Co INDOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THEM AS AN ACTIVE AGENT
GT200500063A (es) * 2004-04-01 2005-10-14 Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias
CN105669540A (zh) 2009-01-28 2016-06-15 卡鲁斯治疗有限公司 Scriptaid电子等排体及其在治疗中的用途
NZ707366A (en) * 2012-11-07 2018-11-30 Karus Therapeutics Ltd Novel histone deacetylase inhibitors and their use in therapy
DK2994465T3 (en) 2013-05-10 2018-10-08 Karus Therapeutics Ltd HISTONDEACETYLASE INHIBITORS UNKNOWN
GB201419264D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
GB201419228D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
CA3104928A1 (en) 2018-08-13 2020-02-20 F. Hoffmann-La Roche Ag New heterocyclic compounds as monoacylglycerol lipase inhibitors
CR20220104A (es) 2019-09-12 2022-04-20 Hoffmann La Roche Compuestos de 4,4a,5,7,8,8a-hexapirido[4,3-b][1,4]oxazin-3-ona como inhibidores de magl

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029657A (en) * 1976-06-14 1977-06-14 The Dow Chemical Company 6,7-Dichloro-3,4-dihydro-2H-pyrazino(2,3-B)(1,4)oxazines
DE2726437A1 (de) * 1977-06-11 1978-12-21 Bayer Ag Hydrazonfarbstoffe
US4880822A (en) * 1987-04-24 1989-11-14 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyridinyl)-1H-indol-1-amines
US4970218A (en) * 1987-04-24 1990-11-13 Hoechst-Roussel Pharmaceuticals Inc. N-(pyridinyl)-1H-indol-1-amines
EP0287982B1 (en) * 1987-04-24 1994-12-07 Hoechst-Roussel Pharmaceuticals Incorporated N-(Pyridinyl)-1H-indol-1-amines, a process for their preparation and their use as medicaments
US5039811A (en) * 1987-04-24 1991-08-13 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-(pyridinyl)-1H-indol-1-amines
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
US5006537A (en) * 1989-08-02 1991-04-09 Hoechst-Roussel Pharmaceuticals, Inc. 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones
EP0415103B1 (en) * 1989-08-02 1995-02-01 Hoechst-Roussel Pharmaceuticals Incorporated 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments
US4983608A (en) * 1989-09-05 1991-01-08 Hoechst-Roussell Pharmaceuticals, Inc. N-substituted-4-pyrimidinamines and pyrimidinediamines

Also Published As

Publication number Publication date
JPH05112572A (ja) 1993-05-07
EP0509400B1 (en) 1996-07-03
PL294221A1 (en) 1993-08-09
IE74907B1 (en) 1997-08-13
HU9201290D0 (en) 1992-07-28
NO301765B1 (no) 1997-12-08
HUT62588A (en) 1993-05-28
ATE140006T1 (de) 1996-07-15
JP2608359B2 (ja) 1997-05-07
DE69211892T2 (de) 1996-12-19
NO921490D0 (no) 1992-04-14
DK0509400T3 (da) 1996-10-28
DE69211892D1 (de) 1996-08-08
NZ242309A (en) 1995-07-26
ES2094840T3 (es) 1997-02-01
IL101589A0 (en) 1992-12-30
AU1485292A (en) 1992-10-22
KR920019796A (ko) 1992-11-20
FI921641A (fi) 1992-10-16
US5276156A (en) 1994-01-04
US5519131A (en) 1996-05-21
NZ248131A (en) 1995-07-26
AU643135B2 (en) 1993-11-04
IE921190A1 (en) 1992-10-21
GR3020612T3 (en) 1996-10-31
RU2042680C1 (ru) 1995-08-27
TW211016B (no) 1993-08-11
CA2065986C (en) 2006-02-21
EP0509400A1 (en) 1992-10-21
FI97544B (fi) 1996-09-30
CA2065986A1 (en) 1992-10-16
FI921641A0 (fi) 1992-04-13
PL168671B1 (pl) 1996-03-29
CS113592A3 (en) 1992-11-18
KR100201509B1 (ko) 1999-06-15
CZ282054B6 (cs) 1997-05-14
FI97544C (fi) 1997-01-10
ZA922721B (en) 1992-11-25
US5214038A (en) 1993-05-25
IL101589A (en) 1996-10-31

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