NO870437D0 - Cykloalkanol(1.2-6)indol-sulfonamider. - Google Patents

Cykloalkanol(1.2-6)indol-sulfonamider.

Info

Publication number: NO870437D0
Authority: NO; Norway
Prior art keywords: cycloalkanols; indole sulfonamides; sulfonamides; indole
Prior art date: 1986-02-21

Application number

NO870437A

Other languages

English (en)

Other versions

NO870437L (no

NO171633B (no

NO171633C (no

Inventor

Horst Boeshagen

Ulrich Rosentreter

Folker Lieb

Hermann Oediger

Friedel Seuter

Elisabeth Perzborn

Volker-Bernd Fiedler

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-02-21

Filing date

1987-02-04

Publication date

1987-02-04

1987-02-04 Application filed by Bayer Ag filed Critical Bayer Ag

1987-02-04 Publication of NO870437D0 publication Critical patent/NO870437D0/no

1987-08-24 Publication of NO870437L publication Critical patent/NO870437L/no

1993-01-04 Publication of NO171633B publication Critical patent/NO171633B/no

1993-04-14 Publication of NO171633C publication Critical patent/NO171633C/no

Links

RYMYQAMZUWJAEO-UHFFFAOYSA-N 1h-indole-2-sulfonamide Chemical class C1=CC=C2NC(S(=O)(=O)N)=CC2=C1 RYMYQAMZUWJAEO-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Hematology (AREA)
Immunology (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO870437A 1986-02-21 1987-02-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive cykloalkano(1.2-b)indol-sulfonamider NO171633C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3605566		1986-02-21
DE19863631824 DE3631824A1 (de)	1986-02-21	1986-09-19	Cycloalkano(1.2-b)indol-sulfonamide

Publications (4)

Publication Number	Publication Date
NO870437D0 true NO870437D0 (no)	1987-02-04
NO870437L NO870437L (no)	1987-08-24
NO171633B NO171633B (no)	1993-01-04
NO171633C NO171633C (no)	1993-04-14

Family

ID=25841196

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO870437A NO171633C (no)	1986-02-21	1987-02-04	Analogifremgangsmaate for fremstilling av terapeutisk aktive cykloalkano(1.2-b)indol-sulfonamider

Country Status (19)

Country	Link
US (3)	US4827032A (no)
EP (1)	EP0242518B1 (no)
JP (1)	JPH075552B2 (no)
KR (2)	KR940007302B1 (no)
AU (1)	AU595855B2 (no)
CA (1)	CA1309414C (no)
CS (1)	CS275837B6 (no)
DE (2)	DE3631824A1 (no)
DK (1)	DK167009B1 (no)
ES (1)	ES2028801T3 (no)
FI (1)	FI86544C (no)
GR (1)	GR3001763T3 (no)
HU (1)	HU198686B (no)
IE (1)	IE59470B1 (no)
IL (1)	IL81611A (no)
NO (1)	NO171633C (no)
NZ (1)	NZ219319A (no)
PH (1)	PH24491A (no)
PT (1)	PT84316B (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3826371A1 (de) *	1988-08-03	1990-02-08	Bayer Ag	Tetrahydro-1-benz-(c,d)-indolpropionsaeure-sulfonamide
DE3829455A1 (de) *	1988-08-31	1990-03-15	Boehringer Mannheim Gmbh	Sulfonamidoalkyl-cyclohexan-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel
US4959383A (en) *	1988-10-31	1990-09-25	E. R. Squibb & Sons, Inc.	Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use
US5006542A (en) *	1988-10-31	1991-04-09	E. R. Squibb & Sons, Inc.	Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US5070099A (en) *	1988-10-31	1991-12-03	E. R. Squibb & Sons, Inc.	Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use
GB8924392D0 (en) *	1989-10-30	1989-12-20	Bayer Ag	Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides
GB9008108D0 (en) *	1990-04-10	1990-06-06	Bayer Ag	Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles
DE4027278A1 (de) *	1990-08-29	1992-03-05	Bayer Ag	Heterocyclisch substituierte indolsulfonamide
US5827871A (en) *	1991-06-26	1998-10-27	Smithkline Beecham Plc	Medicaments 1,2,3,4-tetrahydrocarbazoles and 5-HT1 agonist use thereof
DE4131346A1 (de) *	1991-09-20	1993-03-25	Bayer Ag	Indolsulfonamid substituierte dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
EP0603432B1 (en) *	1992-12-18	1998-10-21	Smithkline Beecham Plc	Tetrahydrocarbazole derivatives for the manufacture of a medicament for the treatment of a disease where a 5-HT1-like agonist is indicated
DE19507751A1 (de) *	1995-03-06	1996-09-12	Bayer Ag	Verfahren zur Herstellung von substituierten 1,2,3,4-Tetrahydrocarbazolen
US5708187A (en) *	1996-06-27	1998-01-13	Eli Lilly And Company	6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta 7,6-B!indoles: New 5-HT1F agonists
DE19757983A1 (de) *	1997-12-24	1999-07-01	Bayer Yakuhin Ltd	Thermodynamisch stabile Form von (r)-3[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazol-0-propansäure (Ramatroban)
US7696222B2 (en) *	2005-08-12	2010-04-13	Merck Frosst Canada Ltd	Indole derivatives as CRTH2 receptor antagonists
US7662831B2 (en) *	2006-07-27	2010-02-16	Wyeth Llc	Tetracyclic indoles as potassium channel modulators
US7601856B2 (en) *	2006-07-27	2009-10-13	Wyeth	Benzofurans as potassium ion channel modulators
AU2007282949B8 (en)	2006-08-07	2012-10-04	Actelion Pharmaceuticals Ltd.	(3-Amino-1,2,3,4-tetrahydro-9H-carbazol-9-yl)-acetic acid derivatives
GB0624087D0 (en) *	2006-12-01	2007-01-10	Selamine Ltd	Ramipril combination salt
GB0624084D0 (en) *	2006-12-01	2007-01-10	Selamine Ltd	Ramipril amino acid salts
GB0624090D0 (en) *	2006-12-01	2007-01-10	Selamine Ltd	Ramipril amine salts
WO2008075028A1 (en) *	2006-12-20	2008-06-26	Cardoz Ab	New combination for use in the treatment of inflammatory disorders
CA2675520A1 (en) *	2007-01-16	2008-07-24	Cardoz Ab	New combination for use in the treatment of inflammatory disorders
WO2009007674A2 (en) *	2007-07-11	2009-01-15	Cardoz Ab	Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and ramatroban or seratrodast
JP2011526281A (ja) *	2008-06-24	2011-10-06	アミラファーマシューティカルズ，インク．	プロスタグランジンｄ２受容体のシクロアルカン［ｂ］インドールアンタゴニスト
CN102099342B (zh) *	2008-07-15	2013-07-10	霍夫曼-拉罗奇有限公司	氨基四氢吲唑基乙酸类
MX2011005200A (es)	2008-11-17	2011-06-01	Hoffmann La Roche	Acidos naftilaceticos.
CA2740863A1 (en)	2008-11-17	2010-05-20	F. Hoffmann-La Roche Ag	Naphthylacetic acids
CN102216273A (zh)	2008-11-17	2011-10-12	霍夫曼-拉罗奇有限公司	用作crth2拮抗剂或部分激动剂的萘乙酸
TWI562987B (en)	2010-03-22	2016-12-21	Actelion Pharmaceuticals Ltd	3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators
EP2697223B1 (en)	2011-04-14	2016-07-13	Actelion Pharmaceuticals Ltd.	7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators
US8470884B2 (en)	2011-11-09	2013-06-25	Hoffmann-La Roche Inc.	Alkenyl naphthylacetic acids
PL3119779T3 (pl)	2014-03-17	2019-01-31	Idorsia Pharmaceuticals Ltd	Pochodne kwasu azaindolooctowego i ich zastosowanie jako modulatorów receptora prostaglandyny d2
JP6484644B2 (ja)	2014-03-18	2019-03-13	イドーシアファーマシューティカルズリミテッドＩｄｏｒｓｉａＰｈａｒｍａｃｅｕｔｉｃａｌｓＬｔｄ	アザインドール酢酸誘導体及びプロスタグランジンｄ２受容体調節剤としてのそれらの使用
MX2018003202A (es)	2015-09-15	2018-06-08	Idorsia Pharmaceuticals Ltd	Formas cristalinas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1415322A (fr) *	1963-12-09	1965-10-22	Eastman Kodak Co	Nouveaux composés de 3-sulfamidocyclobutanone et de 3-sulfamidocyclobutanol
US3642816A (en) *	1967-08-10	1972-02-15	Sterling Drug Inc	3-acetamido-1 2 3 4-tetrahydrocarbazole
JPS4713658Y1 (no) *	1969-12-18	1972-05-18
CH586678A5 (no) *	1970-05-25	1977-04-15	Hoffmann La Roche
DE2226702A1 (de) *	1972-05-25	1973-12-13	Schering Ag	Neue mittel zur behandlung des diabetes mellitus
JPS5186117A (en) *	1975-01-27	1976-07-28	Tanabe Seiyaku Co	Johoseibiryushiseizainoseiho
US4235901A (en) *	1978-05-08	1980-11-25	American Home Products Corporation	1-Hydroxyalkanamine pyrano(3,4-b)indole compositions and use thereof

1986
- 1986-09-19 DE DE19863631824 patent/DE3631824A1/de not_active Withdrawn
1987
- 1987-02-04 NO NO870437A patent/NO171633C/no unknown
- 1987-02-11 EP EP87101901A patent/EP0242518B1/de not_active Expired - Lifetime
- 1987-02-11 DE DE8787101901T patent/DE3769191D1/de not_active Expired - Lifetime
- 1987-02-11 ES ES198787101901T patent/ES2028801T3/es not_active Expired - Lifetime
- 1987-02-13 AU AU68808/87A patent/AU595855B2/en not_active Expired
- 1987-02-18 NZ NZ219319A patent/NZ219319A/en unknown
- 1987-02-18 IL IL81611A patent/IL81611A/xx not_active IP Right Cessation
- 1987-02-19 PH PH34883A patent/PH24491A/en unknown
- 1987-02-19 PT PT84316A patent/PT84316B/pt not_active IP Right Cessation
- 1987-02-19 CA CA000530077A patent/CA1309414C/en not_active Expired - Lifetime
- 1987-02-19 HU HU87650A patent/HU198686B/hu unknown
- 1987-02-19 CS CS871093A patent/CS275837B6/cs unknown
- 1987-02-19 FI FI870693A patent/FI86544C/fi not_active IP Right Cessation
- 1987-02-20 DK DK087187A patent/DK167009B1/da not_active IP Right Cessation
- 1987-02-20 IE IE43987A patent/IE59470B1/en not_active IP Right Cessation
- 1987-02-20 KR KR1019870001410A patent/KR940007302B1/ko not_active IP Right Cessation
- 1987-07-31 KR KR87008383A patent/KR960001914B1/ko not_active IP Right Cessation
1988
- 1988-06-29 US US07/212,840 patent/US4827032A/en not_active Expired - Lifetime
1989
- 1989-02-08 US US07/308,152 patent/US4904797A/en not_active Expired - Lifetime
- 1989-11-28 US US07/442,043 patent/US4965258A/en not_active Expired - Lifetime
1991
- 1991-04-11 GR GR91400361T patent/GR3001763T3/el unknown
1992
- 1992-02-27 JP JP4076232A patent/JPH075552B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR870007885A (ko)	1987-09-22
CS8701093A2 (en)	1990-11-14
US4827032A (en)	1989-05-02
AU595855B2 (en)	1990-04-12
US4904797A (en)	1990-02-27
FI870693A0 (fi)	1987-02-19
AU6880887A (en)	1987-08-27
CA1309414C (en)	1992-10-27
DK87187A (da)	1987-08-22
NO870437L (no)	1987-08-24
KR890001982A (ko)	1989-04-07
NO171633B (no)	1993-01-04
EP0242518A1 (de)	1987-10-28
FI86544B (fi)	1992-05-29
IE59470B1 (en)	1994-03-09
JPH0592954A (ja)	1993-04-16
US4965258A (en)	1990-10-23
PH24491A (en)	1990-07-18
DE3631824A1 (de)	1988-03-31
FI86544C (fi)	1992-09-10
NZ219319A (en)	1990-12-21
PT84316A (en)	1987-03-01
NO171633C (no)	1993-04-14
IE870439L (en)	1987-08-21
FI870693A (fi)	1987-08-22
IL81611A (en)	1991-03-10
ES2028801T3 (es)	1992-07-16
KR960001914B1 (en)	1996-02-06
HUT44493A (en)	1988-03-28
DE3769191D1 (de)	1991-05-16
PT84316B (pt)	1989-09-14
HU198686B (en)	1989-11-28
KR940007302B1 (ko)	1994-08-12
DK87187D0 (da)	1987-02-20
GR3001763T3 (en)	1992-11-23
DK167009B1 (da)	1993-08-16
EP0242518B1 (de)	1991-04-10
CS275837B6 (en)	1992-03-18
JPH075552B2 (ja)	1995-01-25

Publication	Publication Date	Title
NO870437L (no)	1987-08-24	Cykloalkanol(1.2-6)indol-sulfonamider.
LV5742B4 (lv)	1996-12-20	3,5-divalizvietoti pirokatehina atvasinajumi
DE3783669D1 (de)	1993-03-04	Alpha-aryl-alpha-phenethyl-1h-1,2,4-triazol-1-propan-nitrile.
DE3762048D1 (de)	1990-05-03	Antischaummittel.
DE3763411D1 (de)	1990-08-02	1,2,3,6-tetrahydro-5-nitro-pyrimidin-derivate.
FI875619A (fi)	1988-06-23	6-benzoxazinyl- och 6-benzotiazonyl-2,3,4,5-tetrahydropyridazin-3-oner.
DE3787548D1 (de)	1993-11-04	Makrolid-verbindungen.
DE3778190D1 (de)	1992-05-21	Substituierte indolochinoxaline.
FI874428A (fi)	1988-04-11	Foerfarande foer framstaellning av vinylklorid medelst termisk spjaelkning av 1,2-dikloretan.
DE3786025D1 (de)	1993-07-08	Makrolid-verbindungen.
DE3764006D1 (de)	1990-09-06	Substituierte aminoxypropanoate.
DE3765646D1 (de)	1990-11-29	2,5,6,7-tetranor-4,8-inter-m-phenylen-pgi2-derivate.
FI881829A0 (fi)	1988-04-19	1,3-dioxaner.
FI880552A0 (fi)	1988-02-08	Substituerade 2,6-substituerade pyridinfoereningar.
DE3766279D1 (de)	1991-01-03	Substituierte aminoxypropionamide.
FI881899A0 (fi)	1988-04-22	Nya 2 ,16 -diaminoandrostaner.
ES2015605B3 (es)	1990-09-01	3,4-dihidro-2h-piranos.
DE3788163D1 (de)	1993-12-23	1,3,5-Trithian-Derivate.
DK291687D0 (da)	1987-06-04	2-phenylacetyl-1,3,5-cyklohexantrioner
FI880081A (fi)	1988-07-13	2,1-bensotiazepin-2,2-dioxid-5 -karboxylsyraderivat.
ATE58539T1 (de)	1990-12-15	Substituierte pyrimidoindole.
FI874140A0 (fi)	1987-09-22	Elektronisk haollkrets foer via en abonnentledning matade tvaovaegstelefoner.
DE3761091D1 (de)	1990-01-11	2,6-dimethyl-p-benzochinontetraalkylketale.
FI914395A0 (fi)	1991-09-18	Nya 5,6-substituerade 2,4-kinazo- lindiaminer.
DE3770251D1 (de)	1991-06-27	1,1,2-triaryl-1-buten-derivate.