NO781296L - Reagens for bestemmelse av glukosekonsentrasjoner med glukosedehydrogenase - Google Patents

Reagens for bestemmelse av glukosekonsentrasjoner med glukosedehydrogenase

Info

Publication number: NO781296L
Authority: NO; Norway
Prior art keywords: approx; glucose; kinetic; buffer; reagent
Prior art date: 1977-04-28

Application number

NO781296A

Other languages

English (en)

Norwegian (no)

Inventor

Kenneth J Pierre

Ker-Kong Tung

Original Assignee

Beckman Instruments Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-04-28

Filing date

1978-04-13

Publication date

1978-10-31

1978-04-13 Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc

1978-10-31 Publication of NO781296L publication Critical patent/NO781296L/no

Links

239000003153 chemical reaction reagent Substances 0.000 title claims description 52
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims description 50
239000008103 glucose Substances 0.000 title claims description 50
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 28
108010050375 Glucose 1-Dehydrogenase Proteins 0.000 claims description 21
238000000034 method Methods 0.000 claims description 20
239000000872 buffer Substances 0.000 claims description 19
239000005515 coenzyme Substances 0.000 claims description 15
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims description 14
239000008363 phosphate buffer Substances 0.000 claims description 6
LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims description 6
KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 4
108010020056 Hydrogenase Proteins 0.000 claims description 3
239000007983 Tris buffer Substances 0.000 claims description 3
239000003513 alkali Substances 0.000 claims description 3
ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 claims description 3
229910000160 potassium phosphate Inorganic materials 0.000 claims description 3
235000011009 potassium phosphates Nutrition 0.000 claims description 3
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims description 3
238000001514 detection method Methods 0.000 claims description 2
239000001488 sodium phosphate Substances 0.000 claims description 2
229910000162 sodium phosphate Inorganic materials 0.000 claims description 2
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 2
HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 claims 1
238000006243 chemical reaction Methods 0.000 description 8
BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 description 4
239000012086 standard solution Substances 0.000 description 4
238000002835 absorbance Methods 0.000 description 3
229950006238 nadide Drugs 0.000 description 3
229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 3
150000003839 salts Chemical class 0.000 description 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
108090000790 Enzymes Proteins 0.000 description 2
102000004190 Enzymes Human genes 0.000 description 2
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
239000012895 dilution Substances 0.000 description 2
238000010790 dilution Methods 0.000 description 2
239000000203 mixture Substances 0.000 description 2
CXONXVMMINSQBV-NNYOXOHSSA-N (2r,3r,4s,5r)-5-[[[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-2-(3-carbamothioylpyridin-1-ium-1-yl)-4-hydroxyoxolan-3-olate Chemical compound NC(=S)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)[O-])=C1 CXONXVMMINSQBV-NNYOXOHSSA-N 0.000 description 1
BDDLHHRCDSJVKV-UHFFFAOYSA-N 7028-40-2 Chemical compound CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O BDDLHHRCDSJVKV-UHFFFAOYSA-N 0.000 description 1
CNPRPOBKEGWPEX-UHFFFAOYSA-N 7h-purine;pyridine-3-carboxamide Chemical compound C1=NC=C2NC=NC2=N1.NC(=O)C1=CC=CN=C1 CNPRPOBKEGWPEX-UHFFFAOYSA-N 0.000 description 1
239000004254 Ammonium phosphate Substances 0.000 description 1
241000193755 Bacillus cereus Species 0.000 description 1
241000194107 Bacillus megaterium Species 0.000 description 1
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
PHOQVHQSTUBQQK-SQOUGZDYSA-N D-glucono-1,5-lactone Chemical compound OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O PHOQVHQSTUBQQK-SQOUGZDYSA-N 0.000 description 1
101710088194 Dehydrogenase Proteins 0.000 description 1
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
239000005977 Ethylene Substances 0.000 description 1
XJLXINKUBYWONI-NNYOXOHSSA-O NADP(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](OP(O)(O)=O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 XJLXINKUBYWONI-NNYOXOHSSA-O 0.000 description 1
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 description 1
229910000148 ammonium phosphate Inorganic materials 0.000 description 1
235000019289 ammonium phosphates Nutrition 0.000 description 1
238000013459 approach Methods 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
239000013060 biological fluid Substances 0.000 description 1
210000001124 body fluid Anatomy 0.000 description 1
239000010839 body fluid Substances 0.000 description 1
239000001110 calcium chloride Substances 0.000 description 1
229910001628 calcium chloride Inorganic materials 0.000 description 1
238000011088 calibration curve Methods 0.000 description 1
150000003841 chloride salts Chemical class 0.000 description 1
230000002860 competitive effect Effects 0.000 description 1
238000007357 dehydrogenase reaction Methods 0.000 description 1
MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
238000007865 diluting Methods 0.000 description 1
230000002255 enzymatic effect Effects 0.000 description 1
235000012209 glucono delta-lactone Nutrition 0.000 description 1
229960003681 gluconolactone Drugs 0.000 description 1
239000003112 inhibitor Substances 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
230000031700 light absorption Effects 0.000 description 1
238000005259 measurement Methods 0.000 description 1
230000002906 microbiologic effect Effects 0.000 description 1
244000005700 microbiome Species 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
229940101270 nicotinamide adenine dinucleotide (nad) Drugs 0.000 description 1
239000001103 potassium chloride Substances 0.000 description 1
235000011164 potassium chloride Nutrition 0.000 description 1
210000002966 serum Anatomy 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Inorganic materials [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000012064 sodium phosphate buffer Substances 0.000 description 1
239000000243 solution Substances 0.000 description 1
239000000758 substrate Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
-1 thio-NADP Chemical compound 0.000 description 1
210000002700 urine Anatomy 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Emergency Medicine (AREA)
Immunology (AREA)
Microbiology (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

NO781296A 1977-04-28 1978-04-13 Reagens for bestemmelse av glukosekonsentrasjoner med glukosedehydrogenase NO781296L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/791,825 US4120755A (en)	1977-04-28	1977-04-28	Kinetic method for determination of glucose concentrations with glucose dehydrogenase

Publications (1)

Publication Number	Publication Date
NO781296L true NO781296L (no)	1978-10-31

Family

ID=25154903

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO781296A NO781296L (no)	1977-04-28	1978-04-13	Reagens for bestemmelse av glukosekonsentrasjoner med glukosedehydrogenase

Country Status (10)

Country	Link
US (1)	US4120755A (ja)
JP (1)	JPS5814200B2 (ja)
DE (1)	DE2818603A1 (ja)
DK (1)	DK186978A (ja)
FR (1)	FR2389133A1 (ja)
GB (1)	GB1601771A (ja)
IT (1)	IT1094968B (ja)
NL (1)	NL7803613A (ja)
NO (1)	NO781296L (ja)
SE (1)	SE7804882L (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1187388A (en) *	1978-09-20	1985-05-21	American Monitor Corporation	Stabilization of working reagent solutions containing nadh, nadph, and/or enzymes, and the use of such stabilized reagents in enzymes or substrate assays
DE3019450A1 (de) *	1980-05-21	1981-11-26	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur gewinnung von glucosedehydrogenase und hierfuer geeigneter mikroorganismus
DE3211167A1 (de) *	1982-03-26	1983-09-29	Merck Patent Gmbh, 6100 Darmstadt	Testsystem und verfahren zur bestimmung von substanzen in fluessigkeiten
EP0094161A1 (en) *	1982-05-07	1983-11-16	Imperial Chemical Industries Plc	Method for determining glucose content of fluid
US4394444A (en) *	1982-06-21	1983-07-19	Miles Laboratories, Inc.	Cofactor indicator compositions
US4728608A (en) *	1985-04-08	1988-03-01	Cambridge Bioscience Corporation	Bacterial screening system with enhanced shelf life
GB8600679D0 (en) *	1986-01-13	1986-02-19	Imp Group Plc	Chemical analysis of tobacco/smoking-related products
DE3711881A1 (de) *	1987-04-08	1988-10-27	Merck Patent Gmbh	Verfahren zur herstellung von glucosedehydrogenase aus bacillus megaterium
US5250415A (en) *	1987-04-08	1993-10-05	Merck Patent Gesellschaft Mit Beschrankter Haftung	Process for the preparation of glucose dehydrogenase from Bacillus megaterium
US5037738A (en) *	1987-06-03	1991-08-06	Abbott Laboratories	Simultaneous assay for glucose and urea
JPH0286779A (ja) *	1988-09-22	1990-03-27	Amano Pharmaceut Co Ltd	改良型組換えｄｎａ、それを含む形質転換体及びそれを用いた耐熱性グルコースデヒドロゲナーゼの製造法
SE466158B (sv) *	1989-04-25	1992-01-07	Migrata Uk Ltd	Analysmetod foer glukosbestaemning i helblod
SE466157B (sv)	1989-04-25	1992-01-07	Migrata Uk Ltd	Saett att bestaemma glukoshalten hos helblod samt engaangskuvett foer detta
ATE177153T1 (de) *	1990-09-18	1999-03-15	Asahi Chemical Ind	Myo-inositoldehydrogenase
DE69129308T2 (de) *	1991-12-12	1999-01-07	Asahi Kasei Kogyo K.K., Osaka	Hochempfindliche bestimmung von d-3-hydroxybutiersäure oder acetessigsäure und zusammensetzung dafür
US5487384A (en) *	1993-02-25	1996-01-30	Blue Marble Research, Inc.	Kinematic assay of plasma glucose concentration without blood sampling
US5567581A (en) *	1995-03-06	1996-10-22	Diagnostic Reagents, Inc.	Method and kit for enzymatically determining the pH of a specimen
TW200718785A (en) *	2005-11-10	2007-05-16	Toyo Boseki	A process for improving the thermal stability of a composition containing a soluble coenzyme conjugated glucose dehydrogenase (GDH)
US9347958B2 (en)	2014-06-27	2016-05-24	Hemocue Ab	Device and method for determination of an analyte in blood

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CS164231B2 (ja) *	1972-09-28	1975-11-07
DE2349819A1 (de) *	1973-10-04	1975-04-17	Eppendorf Geraetebau Netheler	Verfahren zur enzymkinetischen konzentrationsbestimmung eines substrats

1977
- 1977-04-28 US US05/791,825 patent/US4120755A/en not_active Expired - Lifetime
1978
- 1978-03-22 GB GB11318/78A patent/GB1601771A/en not_active Expired
- 1978-04-05 NL NL7803613A patent/NL7803613A/xx not_active Application Discontinuation
- 1978-04-13 NO NO781296A patent/NO781296L/no unknown
- 1978-04-27 DE DE19782818603 patent/DE2818603A1/de not_active Withdrawn
- 1978-04-27 FR FR7812550A patent/FR2389133A1/fr active Granted
- 1978-04-27 SE SE7804882A patent/SE7804882L/xx unknown
- 1978-04-28 JP JP53050206A patent/JPS5814200B2/ja not_active Expired
- 1978-04-28 DK DK186978A patent/DK186978A/da not_active Application Discontinuation
- 1978-04-28 IT IT22831/78A patent/IT1094968B/it active

Also Published As

Publication number	Publication date
DE2818603A1 (de)	1978-11-09
IT1094968B (it)	1985-08-10
DK186978A (da)	1978-10-29
SE7804882L (sv)	1978-10-29
GB1601771A (en)	1981-11-04
IT7822831A0 (it)	1978-04-28
US4120755A (en)	1978-10-17
FR2389133A1 (fr)	1978-11-24
NL7803613A (nl)	1978-10-31
JPS5814200B2 (ja)	1983-03-17
JPS53137199A (en)	1978-11-30
FR2389133B1 (ja)	1982-09-10

Publication	Publication Date	Title
NO781296L (no)	1978-10-31	Reagens for bestemmelse av glukosekonsentrasjoner med glukosedehydrogenase
Werner et al.	1981	Ultramicro determination of serum triglycerides by bioluminescent assay.
US7368231B2 (en)	2008-05-06	Detection assay for potassium ions using a potassium-dependent urea amidolyase enzyme
CN107641642B (zh)	2021-02-12	一种肌酸激酶同工酶双试剂及其制备方法
NO791493L (no)	1979-11-06	Kinetisk maaling av glucosekonsentrasjon i kroppsvaesker og formuleringer for anvendelse ved denne
Nazar et al.	1979	An improved microfluorometric enzymatic assay for the determination of ammonia
US4012286A (en)	1977-03-15	Determination of creatine phosphokinase in body fluids
CA2045704A1 (en)	1991-12-28	Stable aqueous nadh reagent and kit
CN104673878B (zh)	2017-01-11	一种单体系测定糖化白蛋白与白蛋白浓度比值的试剂盒
JPH02104298A (ja)	1990-04-17	１，５−アンヒドログルシトールの定量法
JPH0391494A (ja)	1991-04-17	分析対象濃度の酵素的測定方法
JP5812285B2 (ja)	2015-11-11	デヒドロゲナーゼまたは対応する基質の測定方法および測定用キット
Dohnal et al.	2010	Comparison of three methods for determination of glucose
US5429930A (en)	1995-07-04	Kinetic enzyme assay for determining the CO2 content of body fluids using PEP carboxylase with inhibitor
AU630486B2 (en)	1992-10-29	Kinetic enzyme assay for determining the co2 content of body fluids using pep carboxylase with inhibitor
WO2009135035A1 (en)	2009-11-05	Enzymatic determination of potassium ions using stable nad(p)h analogs.
US4311791A (en)	1982-01-19	Automated kinetic determination of lactate dehydrogenase isoenzymes in serum
JPH05176797A (ja)	1993-07-20	コレステロールの定量法および定量用試薬
King	1974	Colorimetric Assay
IE47123B1 (en)	1983-12-28	Analytical device
US3838010A (en)	1974-09-24	Photometric method for determining lactic acid dehydrogenase or glucose-6-phosphate dehydrogenase
JP4182859B2 (ja)	2008-11-19	クレアチンキナーゼ測定用液状試薬キットおよびその安定化方法
EP0387697A2 (en)	1990-09-19	Determination of aminotranferases
EP0159513A1 (en)	1985-10-30	Enzymatic inorganic phosphate assay
JPS63146800A (ja)	1988-06-18	無機リンの測定法