NO328979B1 - Anvendelse av diklorbenzylalkohol for fremstilling av et preparat for topisk behandling av inflammasjon - Google Patents
Anvendelse av diklorbenzylalkohol for fremstilling av et preparat for topisk behandling av inflammasjon Download PDFInfo
- Publication number
- NO328979B1 NO328979B1 NO19993355A NO993355A NO328979B1 NO 328979 B1 NO328979 B1 NO 328979B1 NO 19993355 A NO19993355 A NO 19993355A NO 993355 A NO993355 A NO 993355A NO 328979 B1 NO328979 B1 NO 328979B1
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- dichlorobenzyl alcohol
- inflammation
- treatment
- dcba
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 29
- DBHODFSFBXJZNY-UHFFFAOYSA-N 2,4-dichlorobenzyl alcohol Chemical compound OCC1=CC=C(Cl)C=C1Cl DBHODFSFBXJZNY-UHFFFAOYSA-N 0.000 title claims abstract description 25
- 229960004698 dichlorobenzyl alcohol Drugs 0.000 title claims abstract description 25
- 206010061218 Inflammation Diseases 0.000 title claims abstract description 19
- 230000004054 inflammatory process Effects 0.000 title claims abstract description 19
- 230000000699 topical effect Effects 0.000 title claims abstract description 6
- 239000000203 mixture Substances 0.000 title description 16
- 210000004877 mucosa Anatomy 0.000 claims abstract description 5
- 239000000227 bioadhesive Substances 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 10
- 239000000126 substance Substances 0.000 claims description 9
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
- 239000000416 hydrocolloid Substances 0.000 claims description 3
- 230000014759 maintenance of location Effects 0.000 claims description 3
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 3
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 2
- 241000416162 Astragalus gummifer Species 0.000 claims description 2
- 108010010803 Gelatin Proteins 0.000 claims description 2
- 229920000569 Gum karaya Polymers 0.000 claims description 2
- 229920002125 Sokalan® Polymers 0.000 claims description 2
- 241000934878 Sterculia Species 0.000 claims description 2
- 229920001615 Tragacanth Polymers 0.000 claims description 2
- 238000013270 controlled release Methods 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 229920000159 gelatin Polymers 0.000 claims description 2
- 229940014259 gelatin Drugs 0.000 claims description 2
- 235000019322 gelatine Nutrition 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 235000010494 karaya gum Nutrition 0.000 claims description 2
- 239000000231 karaya gum Substances 0.000 claims description 2
- 229940039371 karaya gum Drugs 0.000 claims description 2
- 229920000609 methyl cellulose Polymers 0.000 claims description 2
- 239000001923 methylcellulose Substances 0.000 claims description 2
- 235000010981 methylcellulose Nutrition 0.000 claims description 2
- 229960002900 methylcellulose Drugs 0.000 claims description 2
- 230000002035 prolonged effect Effects 0.000 claims description 2
- 235000010413 sodium alginate Nutrition 0.000 claims description 2
- 239000000661 sodium alginate Substances 0.000 claims description 2
- 229940005550 sodium alginate Drugs 0.000 claims description 2
- 235000010487 tragacanth Nutrition 0.000 claims description 2
- 239000000196 tragacanth Substances 0.000 claims description 2
- 229940116362 tragacanth Drugs 0.000 claims description 2
- MQFLXLMNOHHPTC-UHFFFAOYSA-N 1-isothiocyanato-9-(methylsulfinyl)nonane Chemical compound CS(=O)CCCCCCCCCN=C=S MQFLXLMNOHHPTC-UHFFFAOYSA-N 0.000 claims 2
- 229920000591 gum Polymers 0.000 claims 1
- 230000004968 inflammatory condition Effects 0.000 abstract description 10
- 241000233866 Fungi Species 0.000 abstract description 5
- 241000894006 Bacteria Species 0.000 abstract description 4
- 239000003795 chemical substances by application Substances 0.000 abstract description 4
- 239000006071 cream Substances 0.000 abstract description 4
- 208000006877 Insect Bites and Stings Diseases 0.000 abstract description 3
- 208000003251 Pruritus Diseases 0.000 abstract description 2
- 201000004681 Psoriasis Diseases 0.000 abstract description 2
- 239000000645 desinfectant Substances 0.000 abstract description 2
- 239000002674 ointment Substances 0.000 abstract description 2
- 208000017520 skin disease Diseases 0.000 abstract description 2
- 241000699670 Mus sp. Species 0.000 description 19
- 239000000499 gel Substances 0.000 description 17
- 230000000694 effects Effects 0.000 description 11
- 241001465754 Metazoa Species 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- 239000002324 mouth wash Substances 0.000 description 6
- 229940051866 mouthwash Drugs 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 206010015150 Erythema Diseases 0.000 description 5
- 230000006378 damage Effects 0.000 description 5
- 231100000321 erythema Toxicity 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 230000003110 anti-inflammatory effect Effects 0.000 description 4
- 239000012620 biological material Substances 0.000 description 4
- 230000037396 body weight Effects 0.000 description 4
- 239000000551 dentifrice Substances 0.000 description 4
- 210000000214 mouth Anatomy 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 239000004599 antimicrobial Substances 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 210000005069 ears Anatomy 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 239000002085 irritant Substances 0.000 description 3
- 231100000021 irritant Toxicity 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 210000004400 mucous membrane Anatomy 0.000 description 3
- CQRYARSYNCAZFO-UHFFFAOYSA-N salicyl alcohol Chemical compound OCC1=CC=CC=C1O CQRYARSYNCAZFO-UHFFFAOYSA-N 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241000590002 Helicobacter pylori Species 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000002421 anti-septic effect Effects 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 229960004311 betamethasone valerate Drugs 0.000 description 2
- SNHRLVCMMWUAJD-SUYDQAKGSA-N betamethasone valerate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(OC(=O)CCCC)[C@@]1(C)C[C@@H]2O SNHRLVCMMWUAJD-SUYDQAKGSA-N 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000001055 chewing effect Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 230000000249 desinfective effect Effects 0.000 description 2
- 239000006196 drop Substances 0.000 description 2
- 230000002500 effect on skin Effects 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 125000000524 functional group Chemical group 0.000 description 2
- 229940037467 helicobacter pylori Drugs 0.000 description 2
- -1 household items Substances 0.000 description 2
- 230000000415 inactivating effect Effects 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 230000003232 mucoadhesive effect Effects 0.000 description 2
- 201000001245 periodontitis Diseases 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 239000000606 toothpaste Substances 0.000 description 2
- 229940034610 toothpaste Drugs 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 230000004580 weight loss Effects 0.000 description 2
- 244000215068 Acacia senegal Species 0.000 description 1
- 206010003399 Arthropod bite Diseases 0.000 description 1
- 206010003402 Arthropod sting Diseases 0.000 description 1
- 206010007134 Candida infections Diseases 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- 208000003322 Coinfection Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 208000001695 Dry Socket Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 208000012895 Gastric disease Diseases 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 208000001143 Periodontal Abscess Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000004210 Pressure Ulcer Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 208000000311 Tooth Migration Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 239000013566 allergen Substances 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- CKGWFZQGEQJZIL-UHFFFAOYSA-N amylmetacresol Chemical compound CCCCCC1=CC=C(C)C=C1O CKGWFZQGEQJZIL-UHFFFAOYSA-N 0.000 description 1
- 229960005213 amylmetacresol Drugs 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 201000003984 candidiasis Diseases 0.000 description 1
- 230000002925 chemical effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000008119 colloidal silica Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000008260 defense mechanism Effects 0.000 description 1
- 125000003963 dichloro group Chemical group Cl* 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003221 ear drop Substances 0.000 description 1
- 229940047652 ear drops Drugs 0.000 description 1
- 241001233061 earthworms Species 0.000 description 1
- 230000002884 effect on inflammation Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 238000012332 laboratory investigation Methods 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 235000021056 liquid food Nutrition 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 229940124641 pain reliever Drugs 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000021055 solid food Nutrition 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 210000004357 third molar Anatomy 0.000 description 1
- 230000009974 thixotropic effect Effects 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK2697 | 1997-01-09 | ||
PCT/DK1998/000011 WO1998030214A1 (en) | 1997-01-09 | 1998-01-09 | Use of dichlorobenzyl alcohol for preparing a preparation for topical treatment of inflammation and a preparation containing dichlorobenzyl alcohol |
Publications (3)
Publication Number | Publication Date |
---|---|
NO993355D0 NO993355D0 (no) | 1999-07-07 |
NO993355L NO993355L (no) | 1999-08-18 |
NO328979B1 true NO328979B1 (no) | 2010-07-05 |
Family
ID=8088912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19993355A NO328979B1 (no) | 1997-01-09 | 1999-07-07 | Anvendelse av diklorbenzylalkohol for fremstilling av et preparat for topisk behandling av inflammasjon |
Country Status (18)
Country | Link |
---|---|
US (1) | US6251371B1 (ja) |
EP (1) | EP0988033B1 (ja) |
JP (1) | JP4663036B2 (ja) |
KR (1) | KR100573206B1 (ja) |
CN (1) | CN1128614C (ja) |
AT (1) | ATE206047T1 (ja) |
AU (1) | AU719836B2 (ja) |
BR (1) | BR9807056A (ja) |
CA (1) | CA2277207C (ja) |
DE (1) | DE69801820T2 (ja) |
DK (1) | DK0988033T3 (ja) |
ES (1) | ES2162410T3 (ja) |
NO (1) | NO328979B1 (ja) |
NZ (1) | NZ336600A (ja) |
PL (1) | PL189398B1 (ja) |
PT (1) | PT988033E (ja) |
RU (1) | RU2184538C2 (ja) |
WO (1) | WO1998030214A1 (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL196077B1 (pl) * | 1998-03-19 | 2007-12-31 | Bifodan As | Kompozycja dezynfekująca |
AU2002222589A1 (en) * | 2000-12-08 | 2002-06-18 | Kyowa Hakko Kogyo Co. Ltd. | Oral preprations having itching-relievign or antipruritic activity |
US7887842B2 (en) | 2003-02-07 | 2011-02-15 | Teikoku Pharma Usa, Inc. | Methods of administering a dermatological agent to a subject |
MX2012010769A (es) * | 2010-03-19 | 2013-02-27 | Oxygen Biotherapeutics Inc | Formulaciones perfluorocarbonadas oftalmicas en forma de crema. |
WO2012044963A2 (en) * | 2010-10-01 | 2012-04-05 | Oxygen Biotherapeutics, Inc. | Perfluorocarbons for use in treating pruritus |
CN104173204B (zh) * | 2014-09-17 | 2015-03-11 | 沈广阳 | 一种水包油乳液组合物 |
BR112017005884A2 (pt) * | 2014-09-26 | 2018-02-06 | Koninklijke Philips Nv | sistemas destinados a fornecer uma composição para tratamento bucal, e aplicador adaptado para introduzir uma composição mucoadesiva |
US9980975B2 (en) | 2015-01-22 | 2018-05-29 | Ems S.A. | Dosage forms containing fluticasone propionate for the treatment of inflammatory conditions of the esophagus |
CN111297802A (zh) * | 2018-12-12 | 2020-06-19 | 成都一平医药科技发展有限公司 | 一种用于抗炎及抗菌的组合物 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3123528A (en) * | 1964-03-03 | New therapeutic compositions | ||
BE750969A (fr) * | 1970-05-26 | 1970-11-03 | Geigy Ag J R | Composition pour combattre les micro-organismes, |
US4167583A (en) * | 1973-07-03 | 1979-09-11 | Bayer Aktiengesellschaft | Microbial composition and formulations |
GB8411731D0 (en) * | 1984-05-09 | 1984-06-13 | Unilever Plc | Oral compositions |
US4663077A (en) * | 1984-06-11 | 1987-05-05 | Morton Thiokol Inc. | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein |
GB9108080D0 (en) * | 1991-04-15 | 1991-06-05 | Smithkline Beecham Plc | Pharmaceutical composition |
IL106142A (en) * | 1992-06-29 | 1997-03-18 | Merck & Co Inc | Morpholine and thiomorpholine tachykinin receptor antagonists, their preparation and pharmaceutical compositions containing them |
WO1994018165A1 (en) * | 1993-02-12 | 1994-08-18 | Pfizer Inc. | Sulfonamide compounds as opioid k-receptor agonists |
JPH07242666A (ja) * | 1994-03-08 | 1995-09-19 | Fujisawa Pharmaceut Co Ltd | 複素環化合物 |
US5708023A (en) * | 1994-03-28 | 1998-01-13 | The Trustees Of Columbia University In The City Of New York | Zinc gluconate gel compositions |
CN1158566A (zh) * | 1994-06-20 | 1997-09-03 | 库特·伯格 | 用于预防和/或治疗病毒感染和各种炎症的药物组合物及其治疗方法 |
JP3466350B2 (ja) * | 1994-12-13 | 2003-11-10 | サンメディカル株式会社 | 象牙質知覚過敏症用歯科用組成物 |
CA2165013C (en) * | 1994-12-13 | 2004-01-06 | Nobuo Nakabayashi | Dental composition for relieving dentin hypersensitivity |
IT1275955B1 (it) * | 1995-03-22 | 1997-10-24 | Dompe Spa | Formulazioni farmaceutiche in forma di gel tissotropico |
ZA962455B (en) * | 1995-03-31 | 1996-10-02 | B Eugene Guthery | Fast acting and persistent topical antiseptic |
GB9507883D0 (en) | 1995-04-18 | 1995-05-31 | Retroscreen Ltd | Compounds |
ATE240088T1 (de) * | 1996-12-13 | 2003-05-15 | Vesifact Ag | Kosmetische präparate in form einer nanodispersion |
US5989527A (en) * | 1998-01-26 | 1999-11-23 | Inolex Investment Corporation | Compositions and methods for improving the performance of chemical exfoliating agents, sunless tanning agents, skin lightening agents and insect repellents |
-
1998
- 1998-01-09 ES ES98900272T patent/ES2162410T3/es not_active Expired - Lifetime
- 1998-01-09 US US09/341,427 patent/US6251371B1/en not_active Expired - Lifetime
- 1998-01-09 KR KR1019997006205A patent/KR100573206B1/ko not_active IP Right Cessation
- 1998-01-09 PT PT98900272T patent/PT988033E/pt unknown
- 1998-01-09 PL PL98334679A patent/PL189398B1/pl not_active IP Right Cessation
- 1998-01-09 BR BR9807056-8A patent/BR9807056A/pt not_active Application Discontinuation
- 1998-01-09 NZ NZ336600A patent/NZ336600A/xx not_active IP Right Cessation
- 1998-01-09 DE DE69801820T patent/DE69801820T2/de not_active Expired - Lifetime
- 1998-01-09 WO PCT/DK1998/000011 patent/WO1998030214A1/en active IP Right Grant
- 1998-01-09 EP EP98900272A patent/EP0988033B1/en not_active Expired - Lifetime
- 1998-01-09 DK DK98900272T patent/DK0988033T3/da active
- 1998-01-09 RU RU99117143/14A patent/RU2184538C2/ru active
- 1998-01-09 AU AU54783/98A patent/AU719836B2/en not_active Ceased
- 1998-01-09 AT AT98900272T patent/ATE206047T1/de active
- 1998-01-09 JP JP53047998A patent/JP4663036B2/ja not_active Expired - Fee Related
- 1998-01-09 CA CA002277207A patent/CA2277207C/en not_active Expired - Fee Related
- 1998-01-09 CN CN98801761A patent/CN1128614C/zh not_active Expired - Fee Related
-
1999
- 1999-07-07 NO NO19993355A patent/NO328979B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BR9807056A (pt) | 2000-05-02 |
DK0988033T3 (da) | 2001-10-22 |
NO993355D0 (no) | 1999-07-07 |
PL334679A1 (en) | 2000-03-13 |
RU2184538C2 (ru) | 2002-07-10 |
DE69801820T2 (de) | 2002-04-11 |
US6251371B1 (en) | 2001-06-26 |
PT988033E (pt) | 2002-02-28 |
AU5478398A (en) | 1998-08-03 |
DE69801820D1 (de) | 2001-10-31 |
KR20000069990A (ko) | 2000-11-25 |
ATE206047T1 (de) | 2001-10-15 |
AU719836B2 (en) | 2000-05-18 |
KR100573206B1 (ko) | 2006-04-28 |
EP0988033B1 (en) | 2001-09-26 |
PL189398B1 (pl) | 2005-07-29 |
WO1998030214A1 (en) | 1998-07-16 |
NO993355L (no) | 1999-08-18 |
JP4663036B2 (ja) | 2011-03-30 |
EP0988033A1 (en) | 2000-03-29 |
CA2277207A1 (en) | 1998-07-16 |
CA2277207C (en) | 2008-02-19 |
CN1128614C (zh) | 2003-11-26 |
JP2001507708A (ja) | 2001-06-12 |
ES2162410T3 (es) | 2001-12-16 |
CN1243437A (zh) | 2000-02-02 |
NZ336600A (en) | 2000-07-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6239041B2 (ja) | 微生物感染の治療に使用するためのタマリンド種子多糖 | |
CA2688736C (en) | Novel compositions containing lysozyme and c-1/c-4 polysaccharides and use thereof in oral care, cosmetology and dermatology, contraception, urology and gynecology | |
US20060105000A1 (en) | Compositions for treating infected skin and mucous membrane comprising an anti-microbial agent and an essential oil | |
US20180214596A1 (en) | Wound care products comprising alexidine | |
US20170072024A1 (en) | Antimicrobial composition comprising a carbohydrate, glucose oxidase and zinc oxide | |
US8252335B2 (en) | Healing powder and method of use thereof | |
NO328979B1 (no) | Anvendelse av diklorbenzylalkohol for fremstilling av et preparat for topisk behandling av inflammasjon | |
WO2014085421A1 (en) | Treatment of skin or mucosal pathology | |
VITALIEVICHAVERYANOV et al. | Efficiency of clinical application of phytofilm in treating patients with traumatic lesions of oral mucosa | |
CN114569629A (zh) | 一种祛疤和皮肤修复的组合物及其制备方法 | |
JPH0881348A (ja) | 皮膚外用剤 | |
JP2003055138A (ja) | プロポリス含有シート状化粧料 | |
RU2624502C2 (ru) | Лечебно-профилактический материал для стоматологии | |
RU2790528C1 (ru) | Способ местного лечения эрозивно-язвенной формы плоского лишая слизистой оболочки рта | |
US20220249734A1 (en) | Powdered collagen wound care compositions | |
Bahrawy et al. | Abeer S. Gawish, A Mai S. Attia, A, B Dina A. Osman, C | |
AU631655B2 (en) | Liquid polymer composition, and method of use | |
UA100721U (uk) | Засіб для лікування слизової оболонки порожнини рота та пародонта, який містить повідон-йод, у формі стоматологічної лікарської плівки | |
UA53946A (uk) | Склад для лікування генералізованого пародонтиту у віл-інфікованих | |
BRPI0702738B1 (pt) | Processo de preparação de um dispositivo de liberação controlada de agentes antibióticos ou antissépticos incluídos ou associados em ciclodextrina em uma base de gutapercha, produtos e usos | |
UA23785U (en) | Film composition for treating inflammation in oral mucosa |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |