NO303449B1 - Stereoselektiv syntese av nukleosidanaloger samt bicyklisk forbindelse - Google Patents

Stereoselektiv syntese av nukleosidanaloger samt bicyklisk forbindelse

Info

Publication number: NO303449B1
Authority: NO; Norway
Prior art keywords: pct; formula; image; nucleoside analogues; well
Prior art date: 1993-06-07

Application number

NO950432A

Other languages

English (en)

Other versions

NO950432D0 (no

NO950432L (no

Inventor

Tarek S Mansour

Colleen A Evans

Haolun Jin

Arshad M Siddiqui

Allan H L Tse

Original Assignee

Iaf Biochem Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-07

Filing date

1995-02-06

Publication date

1998-07-13

1995-02-06 Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int

1995-02-06 Publication of NO950432D0 publication Critical patent/NO950432D0/no

1995-03-13 Publication of NO950432L publication Critical patent/NO950432L/no

1998-07-13 Publication of NO303449B1 publication Critical patent/NO303449B1/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/08—Bridged systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

NO950432A 1993-06-07 1995-02-06 Stereoselektiv syntese av nukleosidanaloger samt bicyklisk forbindelse NO303449B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939311709A GB9311709D0 (en)	1993-06-07	1993-06-07	Stereoselective synthesis of nucleoside analogues using bicycle intermediate
PCT/CA1994/000311 WO1994029301A1 (en)	1993-06-07	1994-06-07	Stereoselective synthesis of nucleoside analogues using bicyclic intermediate

Publications (3)

Publication Number	Publication Date
NO950432D0 NO950432D0 (no)	1995-02-06
NO950432L NO950432L (no)	1995-03-13
NO303449B1 true NO303449B1 (no)	1998-07-13

Family

ID=10736757

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO950432A NO303449B1 (no)	1993-06-07	1995-02-06	Stereoselektiv syntese av nukleosidanaloger samt bicyklisk forbindelse

Country Status (22)

Country	Link
US (1)	US5763606A (no)
EP (1)	EP0654031B1 (no)
JP (1)	JP3110461B2 (no)
KR (1)	KR100304072B1 (no)
CN (1)	CN1046720C (no)
AT (1)	ATE188215T1 (no)
AU (1)	AU668829B2 (no)
BR (1)	BR9405423A (no)
CA (1)	CA2141029C (no)
DE (1)	DE69422374T2 (no)
DK (1)	DK0654031T3 (no)
ES (1)	ES2139744T3 (no)
FI (1)	FI112078B (no)
GB (1)	GB9311709D0 (no)
HK (1)	HK1008673A1 (no)
HU (1)	HU219199B (no)
NO (1)	NO303449B1 (no)
NZ (1)	NZ267379A (no)
OA (1)	OA10349A (no)
PL (1)	PL180870B1 (no)
RU (1)	RU2139870C1 (no)
WO (1)	WO1994029301A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6175008B1 (en) *	1988-04-11	2001-01-16	Biochem Pharma Inc.	Processes for preparing substituted 1,3-oxathiolanes with antiviral properties
WO1996012716A1 (en) *	1994-10-22	1996-05-02	Chong Kun Dang Corp.	Nucleoside derivatives and process for preparing thereof
KR100856416B1 (ko)	1998-08-12	2008-09-04	길리애드 사이언시즈, 인코포레이티드	1,3-옥사티올란 뉴클레오시드의 제조 방법
US6979561B1 (en) *	1998-10-09	2005-12-27	Gilead Sciences, Inc.	Non-homogeneous systems for the resolution of enantiomeric mixtures
CA2308559C (en)	2000-05-16	2005-07-26	Brantford Chemicals Inc.	1,3-oxathiolan-5-ones useful in the production of antiviral nucleoside analogues
AU2002335489B2 (en) *	2001-03-01	2008-06-05	Abbott Laboratories	Polymorphic and other crystalline forms of cis-FTC
US20040224917A1 (en)	2003-01-14	2004-11-11	Gilead Sciences, Inc.	Compositions and methods for combination antiviral therapy
CN105039489A (zh) *	2004-02-03	2015-11-11	埃莫里大学	制备1,3-二氧戊环核苷的方法
TWI471145B (zh)	2005-06-13	2015-02-01	Bristol Myers Squibb & Gilead Sciences Llc	單一式藥學劑量型
TWI375560B (en)	2005-06-13	2012-11-01	Gilead Sciences Inc	Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5047407A (en) *	1989-02-08	1991-09-10	Iaf Biochem International, Inc.	2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
US5204466A (en) *	1990-02-01	1993-04-20	Emory University	Method and compositions for the synthesis of bch-189 and related compounds
GB9009861D0 (en) *	1990-05-02	1990-06-27	Glaxo Group Ltd	Chemical compounds
AU9125991A (en) *	1990-12-05	1992-07-08	University Of Georgia Research Foundation, Inc., The	Enantiomerically pure beta -l-(-)-1,3-oxathiolane nucleosides
ZA923640B (en) *	1991-05-21	1993-02-24	Iaf Biochem Int	Processes for the diastereoselective synthesis of nucleosides
GB9116601D0 (en) *	1991-08-01	1991-09-18	Iaf Biochem Int	1,3-oxathiolane nucleoside analogues
US5332814A (en) *	1991-11-12	1994-07-26	Ciba-Geigy Corporation	Process for the preparation of carbacyclic nucleosides, and intermediates

1993
- 1993-06-07 GB GB939311709A patent/GB9311709D0/en active Pending
- 1993-11-19 OA OA60438A patent/OA10349A/en unknown
1994
- 1994-06-07 KR KR1019950700453A patent/KR100304072B1/ko not_active IP Right Cessation
- 1994-06-07 NZ NZ267379A patent/NZ267379A/en not_active IP Right Cessation
- 1994-06-07 BR BR9405423A patent/BR9405423A/pt not_active Application Discontinuation
- 1994-06-07 AT AT94918252T patent/ATE188215T1/de not_active IP Right Cessation
- 1994-06-07 HU HU9500364A patent/HU219199B/hu not_active IP Right Cessation
- 1994-06-07 CA CA002141029A patent/CA2141029C/en not_active Expired - Fee Related
- 1994-06-07 AU AU69667/94A patent/AU668829B2/en not_active Ceased
- 1994-06-07 ES ES94918252T patent/ES2139744T3/es not_active Expired - Lifetime
- 1994-06-07 DK DK94918252T patent/DK0654031T3/da active
- 1994-06-07 DE DE69422374T patent/DE69422374T2/de not_active Expired - Fee Related
- 1994-06-07 RU RU95108553A patent/RU2139870C1/ru not_active IP Right Cessation
- 1994-06-07 WO PCT/CA1994/000311 patent/WO1994029301A1/en active IP Right Grant
- 1994-06-07 JP JP07501139A patent/JP3110461B2/ja not_active Expired - Fee Related
- 1994-06-07 CN CN94190356A patent/CN1046720C/zh not_active Expired - Fee Related
- 1994-06-07 EP EP94918252A patent/EP0654031B1/en not_active Expired - Lifetime
- 1994-06-07 US US08/379,644 patent/US5763606A/en not_active Expired - Fee Related
- 1994-06-07 PL PL94307350A patent/PL180870B1/pl not_active IP Right Cessation
1995
- 1995-02-06 NO NO950432A patent/NO303449B1/no unknown
- 1995-02-07 FI FI950535A patent/FI112078B/fi active
1998
- 1998-07-02 HK HK98108821A patent/HK1008673A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2139744T3 (es)	2000-02-16
HUT73630A (en)	1996-08-28
HU9500364D0 (en)	1995-05-29
AU6966794A (en)	1995-01-03
FI112078B (fi)	2003-10-31
US5763606A (en)	1998-06-09
PL180870B1 (pl)	2001-04-30
FI950535A0 (fi)	1995-02-07
CA2141029A1 (en)	1994-12-22
HU219199B (en)	2001-03-28
EP0654031A1 (en)	1995-05-24
CN1110479A (zh)	1995-10-18
RU2139870C1 (ru)	1999-10-20
AU668829B2 (en)	1996-05-16
JPH08505643A (ja)	1996-06-18
NO950432D0 (no)	1995-02-06
WO1994029301A1 (en)	1994-12-22
JP3110461B2 (ja)	2000-11-20
DK0654031T3 (da)	2000-06-13
ATE188215T1 (de)	2000-01-15
DE69422374T2 (de)	2000-06-29
CA2141029C (en)	2000-07-25
EP0654031B1 (en)	1999-12-29
BR9405423A (pt)	1999-05-25
RU95108553A (ru)	1996-11-20
KR100304072B1 (ko)	2001-11-22
NO950432L (no)	1995-03-13
CN1046720C (zh)	1999-11-24
DE69422374D1 (de)	2000-02-03
OA10349A (en)	2001-10-18
FI950535A (fi)	1995-02-07
NZ267379A (en)	1997-04-24
HK1008673A1 (en)	1999-05-14
GB9311709D0 (en)	1993-07-21
PL307350A1 (en)	1995-05-15

Publication	Publication Date	Title
TW262474B (no)	1995-11-11
NZ237132A (en)	1993-04-28	Preparation of substituted oxetanones from beta-hydroxy-omega-lactones; various beta-hydroxy and beta-keto-omega-lactones
NO303449B1 (no)	1998-07-13	Stereoselektiv syntese av nukleosidanaloger samt bicyklisk forbindelse
MY128846A (en)	2007-02-28	Preparation of purines
Prugh et al.	1982	Methyl 3-0-benzyl-2, 4, 6-trideoxy-6-iodo-α-d-erythro-hexopyranoside, a chiral synthon for the synthesis of inhibitors of HMG-CoA reductase
CA2098989A1 (en)	1992-07-04	Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines
KR910006288A (ko)	1991-04-29	신규 제조방법
IL74269A0 (en)	1985-05-31	2-alkoxyaminosulfonylbenzene-sulfonylureas,their production and their use as herbicides
ATE207908T1 (de)	2001-11-15	Verfahren zur herstellung von 2-alkoxy-6- (trifluormethyl)-pyrimidin-4-ol
EP0393611A3 (en)	1991-01-23	Novel process for producing oxetanocin g
ATE548366T1 (de)	2012-03-15	Verfahren zur herstellung von dioxolan nukleosidanalogavorstufen
HU896057D0 (en)	1991-07-29	(15,25,3r,5r)-2-[(3s)]-2-halogen-3-hydroxy-1-alkene-inyl]-3-trialkyl-silyl-oxy-7,7-(2,2-dimethyl-trimethylene-dioxy)-bicyclo(3.3.0) octane derivatives and process for producing them
HU9202679D0 (en)	1992-12-28	Method for producing uracyl derivatives
ES8500914A1 (es)	1984-11-01	"procedimiento para la obtencion de un compuesto derivado de la 1-pirimidincarboxamida"
ES2138535A1 (es)	2000-01-01	Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir.
Zhuk et al.	1978	2-/5-Substituted uracil-1-yl/tetrahydrofuran-5-carboxylic acids as pyrimidine nucleotide analogues
HUT36094A (en)	1985-08-28	Process for producing 4-quinolinones
MX9705481A (es)	1998-08-30	Farmacos.