NO20091326L - Indazolderivater som modulatorer av interleukin-1-reseptor-assosiert kinase - Google Patents

Indazolderivater som modulatorer av interleukin-1-reseptor-assosiert kinase

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Publication number
NO20091326L
NO20091326L NO20091326A NO20091326A NO20091326L NO 20091326 L NO20091326 L NO 20091326L NO 20091326 A NO20091326 A NO 20091326A NO 20091326 A NO20091326 A NO 20091326A NO 20091326 L NO20091326 L NO 20091326L
Authority
NO
Norway
Prior art keywords
modulators
interleukin
receptor
associated kinase
indazole derivatives
Prior art date
Application number
NO20091326A
Other languages
English (en)
Inventor
Edward Yin-Shiang Lin
Kevin Guckian
Charles Jewell
Patrick Conlan
Timothy Chan
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of NO20091326L publication Critical patent/NO20091326L/no

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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Abstract

Nærværende oppfinnelse har å gjøre med modulatorer av IRAK-kinaser med formel (I) og gir sammensetninger bestående av slike modulatorer, så vel som metoder for å behandle IRAK-formidlede eller IRAK-assosierte tilstander eller sykdommer. (I)
NO20091326A 2006-09-07 2009-04-01 Indazolderivater som modulatorer av interleukin-1-reseptor-assosiert kinase NO20091326L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84280106P 2006-09-07 2006-09-07
PCT/US2007/019588 WO2008030584A2 (en) 2006-09-07 2007-09-07 Indazole derivatives as modulators of interleukin- 1 receptor-associated kinase

Publications (1)

Publication Number Publication Date
NO20091326L true NO20091326L (no) 2009-04-01

Family

ID=39157878

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091326A NO20091326L (no) 2006-09-07 2009-04-01 Indazolderivater som modulatorer av interleukin-1-reseptor-assosiert kinase

Country Status (15)

Country Link
US (1) US8293923B2 (no)
EP (1) EP2061786A2 (no)
JP (1) JP2010502717A (no)
KR (1) KR20090049076A (no)
CN (1) CN101616910A (no)
AU (1) AU2007292929A1 (no)
BR (1) BRPI0716549A2 (no)
CA (1) CA2663100A1 (no)
IL (1) IL197274A0 (no)
MX (1) MX2009002377A (no)
NO (1) NO20091326L (no)
NZ (1) NZ575410A (no)
RU (1) RU2459821C2 (no)
WO (1) WO2008030584A2 (no)
ZA (1) ZA200901529B (no)

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JP6483624B2 (ja) * 2013-02-07 2019-03-13 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ ピリダジノン−アミド誘導体
US20160166576A1 (en) 2013-07-11 2016-06-16 Merck Sharp & Dohme Corp. Substituted amidopyrazole inhibitors of interleukin receptor-associated kinases (irak-4)
TWI667233B (zh) 2013-12-19 2019-08-01 德商拜耳製藥公司 新穎吲唑羧醯胺，其製備方法、含彼等之醫藥製劑及其製造醫藥之用途
US10160753B2 (en) 2014-01-10 2018-12-25 Aurigene Discovery Technologies Limited Indazole compounds as IRAK4 inhibitors
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Also Published As

Publication number Publication date
US8293923B2 (en) 2012-10-23
WO2008030584A2 (en) 2008-03-13
KR20090049076A (ko) 2009-05-15
MX2009002377A (es) 2009-03-13
NZ575410A (en) 2012-03-30
BRPI0716549A2 (pt) 2013-09-24
AU2007292929A1 (en) 2008-03-13
US20110152260A1 (en) 2011-06-23
CA2663100A1 (en) 2008-03-13
WO2008030584A3 (en) 2008-07-17
CN101616910A (zh) 2009-12-30
IL197274A0 (en) 2009-12-24
ZA200901529B (en) 2009-11-25
RU2459821C2 (ru) 2012-08-27
RU2009112598A (ru) 2010-10-20
EP2061786A2 (en) 2009-05-27
JP2010502717A (ja) 2010-01-28

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