NO20082719L - Aryl-isoksazol-4-yl-oksadiazolderivater - Google Patents

Aryl-isoksazol-4-yl-oksadiazolderivater

Info

Publication number
NO20082719L
NO20082719L NO20082719A NO20082719A NO20082719L NO 20082719 L NO20082719 L NO 20082719L NO 20082719 A NO20082719 A NO 20082719A NO 20082719 A NO20082719 A NO 20082719A NO 20082719 L NO20082719 L NO 20082719L
Authority
NO
Norway
Prior art keywords
lower alkyl
halogen
heteroaryl
heterocyclyl
optionally substituted
Prior art date
Application number
NO20082719A
Other languages
English (en)
Norwegian (no)
Inventor
Andreas Koblet
Bernd Buettelmann
Bo Han
Henner Knust
Andrew Thomas
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20082719L publication Critical patent/NO20082719L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20082719A 2005-12-23 2008-06-13 Aryl-isoksazol-4-yl-oksadiazolderivater NO20082719L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05112956 2005-12-23
PCT/EP2006/069625 WO2007071598A1 (en) 2005-12-23 2006-12-13 Aryl-isoxazolo-4-yl-oxadiazole derivatives

Publications (1)

Publication Number Publication Date
NO20082719L true NO20082719L (no) 2008-09-16

Family

ID=37891460

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082719A NO20082719L (no) 2005-12-23 2008-06-13 Aryl-isoksazol-4-yl-oksadiazolderivater

Country Status (16)

Country Link
US (2) US7541372B2 (es)
EP (1) EP1968972B1 (es)
JP (1) JP5015172B2 (es)
KR (1) KR101121240B1 (es)
CN (1) CN101346372B (es)
AR (1) AR058719A1 (es)
AU (1) AU2006328602B2 (es)
BR (1) BRPI0620146A2 (es)
CA (1) CA2633425A1 (es)
ES (1) ES2397401T3 (es)
IL (1) IL192092A0 (es)
NO (1) NO20082719L (es)
RU (1) RU2426731C2 (es)
TW (1) TWI324602B (es)
WO (1) WO2007071598A1 (es)
ZA (1) ZA200805411B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1968973T3 (pl) 2005-12-27 2012-03-30 Hoffmann La Roche Pochodne aryloizoksazol-4-iloimidazolu
WO2008016123A1 (fr) * 2006-08-03 2008-02-07 Takeda Pharmaceutical Company Limited INHIBITEUR DE LA GSK-3β
EP2137158A4 (en) * 2007-02-28 2012-04-18 Methylgene Inc LOW-MOLECULAR INHIBITORS OF PROTEINARGININE METHYLTRANSFERASES (PRMTS)
FR2913886B1 (fr) 2007-03-22 2012-03-02 Guerbet Sa Utilisation de nanoparticules metalliques dans le diagnostique de la maladie d'alzheimer
BRPI0820112B8 (pt) * 2007-12-04 2021-05-25 Hoffmann La Roche derivados de isoxazol-piridina, seu uso e processos de preparação e medicamento
HUE025984T2 (hu) * 2008-05-14 2016-05-30 Scripps Research Inst Szfingozin foszfát receptor új modulátorai
TW201033201A (en) * 2009-02-19 2010-09-16 Hoffmann La Roche Isoxazole-isoxazole and isoxazole-isothiazole derivatives
WO2010126002A1 (ja) * 2009-04-28 2010-11-04 塩野義製薬株式会社 ヘテロ環スルホンアミド化合物を含有する医薬
JP2012180281A (ja) * 2009-06-29 2012-09-20 Dainippon Sumitomo Pharma Co Ltd 新規オキサジアゾール誘導体
RU2013139662A (ru) * 2011-01-28 2015-03-10 4-Эс-Си Дискавери Гмбх Ингибирование il17 и ifn-гамма для лечения аутоиммунного воспаления
BR112014001083B8 (pt) * 2011-09-19 2022-06-14 Suven Life Sciences Ltd Composto, processo para a preparação de um composto, composição farmacêutica, uso da composiçâo farmacêutica e uso do composto
US8604062B2 (en) 2011-10-20 2013-12-10 Hoffman-La Roche Inc. Process for the preparation of isoxazolyl-methoxy nicotinic acids
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
WO2014001278A1 (en) 2012-06-26 2014-01-03 Aniona Aps A phenyl triazole derivative and its use for modulating the gabaa receptor complex
WO2014001279A1 (en) 2012-06-26 2014-01-03 Aniona Aps A phenyl triazole derivative and its use for modulating the gabaa receptor complex
CN104411699B (zh) 2012-06-26 2017-06-13 萨尼奥纳有限责任公司 苯基***衍生物及其用于调节gabaa 受体复合体的用途
US9475797B2 (en) 2012-06-26 2016-10-25 Saniona A/S Phenyl triazole derivative and its use for modulating the GABAA receptor complex
WO2014001280A1 (en) 2012-06-26 2014-01-03 Aniona Aps A phenyl triazole derivative and its use for modulating the gabaa receptor complex
PL3319959T3 (pl) 2015-07-06 2022-02-14 Alkermes, Inc. Hetero-haloinhibitory deacetylazy histonowej
WO2017007755A1 (en) 2015-07-06 2017-01-12 Rodin Therapeutics, Inc. Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
EP3568135B1 (en) 2017-01-11 2021-04-07 Alkermes, Inc. Bicyclic inhibitors of histone deacetylase
EP3638235A4 (en) 2017-06-14 2021-06-09 Trevena, Inc. COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING IT
JP7152471B2 (ja) 2017-08-07 2022-10-12 ロダン・セラピューティクス，インコーポレーテッド ヒストン脱アセチル化酵素の二環阻害剤
IL275490B2 (en) 2017-12-22 2024-05-01 Ravenna Pharmaceuticals Inc Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors
BR102019014802A2 (pt) 2018-07-20 2020-02-04 Boehringer Ingelheim Int difluorometil-fenil triazóis
WO2021101854A1 (en) 2019-11-19 2021-05-27 Trevena, Inc. Compounds and methods of preparing compounds s1p1 modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808663D0 (en) * 1998-04-23 1998-06-24 Merck Sharp & Dohme Therapeutic agents
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
IT1314191B1 (it) 1999-10-18 2002-12-06 Recordati Chem Pharm Derivati isossazolcarbossamidici
PA8535601A1 (es) 2000-12-21 2002-11-28 Pfizer Derivados benzimidazol y piridilimidazol como ligandos para gabaa
GB0108475D0 (en) 2001-04-04 2001-05-23 Merck Sharp & Dohme New compounds
KR20040027870A (ko) 2001-07-05 2004-04-01 시냅틱 파마세틱칼 코포레이션 Ｍｃｈ 선택적인 안타고니스트로서의 치환 아닐린 피페리딘
GB0128160D0 (en) 2001-11-23 2002-01-16 Merck Sharp & Dohme Novel compounds
EP1773807A2 (en) 2004-06-14 2007-04-18 Takeda San Diego, Inc. Kinase inhibitors
US7351724B2 (en) * 2004-10-15 2008-04-01 The Scripps Research Institute Oxadiazole ketone inhibitors of fatty acid amide hydrolase
US20070060589A1 (en) * 2004-12-21 2007-03-15 Purandare Ashok V Inhibitors of protein arginine methyl transferases

Also Published As

Publication number Publication date
TW200732329A (en) 2007-09-01
KR20080080213A (ko) 2008-09-02
EP1968972B1 (en) 2012-11-28
EP1968972A1 (en) 2008-09-17
ES2397401T3 (es) 2013-03-06
AU2006328602B2 (en) 2012-05-31
US7956074B2 (en) 2011-06-07
CA2633425A1 (en) 2007-06-28
US20070161686A1 (en) 2007-07-12
US7541372B2 (en) 2009-06-02
AR058719A1 (es) 2008-02-20
JP5015172B2 (ja) 2012-08-29
AU2006328602A1 (en) 2007-06-28
IL192092A0 (en) 2008-12-29
CN101346372A (zh) 2009-01-14
JP2009520751A (ja) 2009-05-28
TWI324602B (en) 2010-05-11
KR101121240B1 (ko) 2012-06-12
WO2007071598A1 (en) 2007-06-28
RU2426731C2 (ru) 2011-08-20
US20090197875A1 (en) 2009-08-06
RU2008124198A (ru) 2010-01-27
CN101346372B (zh) 2011-09-28
BRPI0620146A2 (pt) 2011-11-01
ZA200805411B (en) 2009-07-29

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Legal Events

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