NO20081071L - Makrocykliske inhibitorer av hepatitt C virus - Google Patents

Makrocykliske inhibitorer av hepatitt C virus

Info

Publication number
NO20081071L
NO20081071L NO20081071A NO20081071A NO20081071L NO 20081071 L NO20081071 L NO 20081071L NO 20081071 A NO20081071 A NO 20081071A NO 20081071 A NO20081071 A NO 20081071A NO 20081071 L NO20081071 L NO 20081071L
Authority
NO
Norway
Prior art keywords
hepatitis
virus
inhibitors
macrocyclic inhibitors
formula
Prior art date
Application number
NO20081071A
Other languages
English (en)
Inventor
Herman Augustinus De Kock
Abdellah Tahri
Pierre Jean-Marie Raboisson
Kenneth Alan Simmen
Sandrine Marie Helene Vendeville
Lili Hu
Wim Van De Vreken
David Craig Mcgowan
Dominique Louis Nestor Surleraux
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37036843&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20081071(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of NO20081071L publication Critical patent/NO20081071L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Inhibitorer av HCV med formel (I). og iV-oksidene, saltene, og de stereokjemiske isomerformene derav, hvori RR, L, n og p er som definert her. Farmasøytiske sammensetninger som inneholder forbindelser (I) og fremgangsmåter for fremstilling av forbindelser (I). Biotilgjengelige kombinasjoner av inhibitorene av HCV med formel (I) med ritonavir er også tilveiebrakt.
NO20081071A 2005-07-29 2008-02-29 Makrocykliske inhibitorer av hepatitt C virus NO20081071L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05107067 2005-07-29
EP05107413 2005-08-11
PCT/EP2006/064813 WO2007014919A1 (en) 2005-07-29 2006-07-28 Macrocylic inhibitors of hepatitis c virus

Publications (1)

Publication Number Publication Date
NO20081071L true NO20081071L (no) 2008-04-25

Family

ID=37036843

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081071A NO20081071L (no) 2005-07-29 2008-02-29 Makrocykliske inhibitorer av hepatitt C virus

Country Status (28)

Country Link
US (1) US7989471B2 (no)
EP (1) EP1912995B1 (no)
JP (1) JP5426163B2 (no)
KR (1) KR101074673B1 (no)
CN (1) CN101233137B (no)
AP (1) AP2473A (no)
AR (1) AR055104A1 (no)
AT (1) ATE517902T1 (no)
AU (1) AU2006274858B2 (no)
BR (1) BRPI0614670A2 (no)
CA (1) CA2617095C (no)
DK (1) DK1912995T3 (no)
EA (1) EA014646B1 (no)
GT (1) GT200600341A (no)
HK (1) HK1116772A1 (no)
IL (1) IL188283A (no)
JO (1) JO2768B1 (no)
MX (1) MX2008001395A (no)
MY (1) MY152153A (no)
NO (1) NO20081071L (no)
NZ (1) NZ564541A (no)
PE (1) PE20070221A1 (no)
SG (1) SG163613A1 (no)
SI (1) SI1912995T1 (no)
SV (1) SV2008002639A (no)
TW (1) TWI412534B (no)
UY (1) UY29705A1 (no)
WO (1) WO2007014919A1 (no)

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WO2013106631A1 (en) 2012-01-11 2013-07-18 Abbvie Inc. Processes for making hcv protease inhibitors
BR112015007887A2 (pt) 2012-10-08 2017-07-04 Abbvie Inc compostos úteis para produzir inibidores hcv protease
SI2909205T1 (sl) 2012-10-19 2017-02-28 Bristol-Myers Squibb Company 9-metil substituiran heksadekahidrociklopropa(e)pirolo(1,2-A)(1,4)diazaciklopentadecinil karbamat derivati kot nestrukturalni 3 (NS3) proteazni inhibitorji za zdravljenje hepatitis C virusnih infekcij
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Also Published As

Publication number Publication date
US20100240698A1 (en) 2010-09-23
CN101233137B (zh) 2014-05-07
MY152153A (en) 2014-08-15
US7989471B2 (en) 2011-08-02
KR20080041651A (ko) 2008-05-13
KR101074673B1 (ko) 2011-10-19
SI1912995T1 (sl) 2011-11-30
EP1912995B1 (en) 2011-07-27
IL188283A0 (en) 2008-04-13
ATE517902T1 (de) 2011-08-15
SV2008002639A (es) 2008-07-23
UY29705A1 (es) 2007-05-31
PE20070221A1 (es) 2007-04-16
CA2617095C (en) 2014-05-13
MX2008001395A (es) 2008-04-16
AU2006274858A1 (en) 2007-02-08
GT200600341A (es) 2007-02-26
BRPI0614670A2 (pt) 2011-04-12
AP2473A (en) 2012-09-24
SG163613A1 (en) 2010-08-30
IL188283A (en) 2016-12-29
WO2007014919A1 (en) 2007-02-08
AU2006274858B2 (en) 2012-05-24
AR055104A1 (es) 2007-08-08
NZ564541A (en) 2010-03-26
CN101233137A (zh) 2008-07-30
DK1912995T3 (da) 2011-10-24
EA200800484A1 (ru) 2008-06-30
JP5426163B2 (ja) 2014-02-26
HK1116772A1 (en) 2009-01-02
EP1912995A1 (en) 2008-04-23
JO2768B1 (en) 2014-03-15
EA014646B1 (ru) 2010-12-30
JP2009502882A (ja) 2009-01-29
CA2617095A1 (en) 2007-02-08
TW200745165A (en) 2007-12-16
TWI412534B (zh) 2013-10-21

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