NO20074564L - En fremgangsmate, anordning og system for volumetrisk opptelling av hvite blodceller - Google Patents

En fremgangsmate, anordning og system for volumetrisk opptelling av hvite blodceller

Info

Publication number
NO20074564L
NO20074564L NO20074564A NO20074564A NO20074564L NO 20074564 L NO20074564 L NO 20074564L NO 20074564 A NO20074564 A NO 20074564A NO 20074564 A NO20074564 A NO 20074564A NO 20074564 L NO20074564 L NO 20074564L
Authority
NO
Norway
Prior art keywords
sample
white blood
blood
measuring apparatus
blood sample
Prior art date
Application number
NO20074564A
Other languages
English (en)
Other versions
NO340137B1 (no
Inventor
Johnny Svensson
Stellan Lindberg
Original Assignee
Hemocue Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemocue Ab filed Critical Hemocue Ab
Publication of NO20074564L publication Critical patent/NO20074564L/no
Publication of NO340137B1 publication Critical patent/NO340137B1/no

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229—Pumps for assisting the blood sampling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150343—Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
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    • G01N15/1429—Signal processing
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0321—One time use cells, e.g. integrally moulded
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0325—Cells for testing reactions, e.g. containing reagents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/11—Filling or emptying of cuvettes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Theoretical Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Signal Processing (AREA)
  • Manufacturing & Machinery (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Ecology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)

Abstract

En prøveoppnåelsesanordning for volumetrisk opptelling av hvite blodceller i en blodprøve omfattende en målekavitet for å oppnå en blodprøve. Målekaviteten har en forutbestemt fast tykkelse. Prøveoppnåelsesanordningen omfatter videre en reagens, hvilket arrangeres i en tørket form på en overflate definerende målekaviteten. Reagensen omfatter et hemolyserende middel for å lysere røde blodceller i blodprøven, og et fargemiddel for å selektivt farge hvite blodceller i blodprøven. Et system omfattende prøveoppnåelsesanordningen og et måleapparat. Måleapparatet omfatter en prøveoppnåelses-anordningsholder, en lyskilde, og et avbildningssystem for å oppnå et digitalt bilde av en forstørrelse av prøven. Måleapparatet omfatter videre en bildeanalysator arrangert for å analysere det oppnådde digitale bildet for å bestemme antallet av hvite blodceller i blodprøven.
NO20074564A 2005-03-11 2007-09-10 En fremgangsmåte, anordning og system for volumetrisk opptelling av hvite blodceller NO340137B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0500549A SE528697C2 (sv) 2005-03-11 2005-03-11 Volymetrisk bestämning av antalet vita blodkroppar i ett blodprov
PCT/SE2006/000311 WO2006096126A1 (en) 2005-03-11 2006-03-10 A method, device and system for volumetric enumeration of white blood cells.

Publications (2)

Publication Number Publication Date
NO20074564L true NO20074564L (no) 2007-12-11
NO340137B1 NO340137B1 (no) 2017-03-13

Family

ID=36538562

Family Applications (1)

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NO20074564A NO340137B1 (no) 2005-03-11 2007-09-10 En fremgangsmåte, anordning og system for volumetrisk opptelling av hvite blodceller

Country Status (19)

Country Link
US (2) US7521243B2 (no)
EP (1) EP1701150B1 (no)
JP (1) JP4642893B2 (no)
KR (1) KR101244234B1 (no)
CN (1) CN101137904B (no)
AU (1) AU2006221130B2 (no)
BR (1) BRPI0608340B8 (no)
CA (1) CA2599747C (no)
DK (1) DK1701150T3 (no)
LT (1) LT1701150T (no)
MX (1) MX2007011104A (no)
MY (1) MY143768A (no)
NO (1) NO340137B1 (no)
PL (1) PL1701150T3 (no)
PT (1) PT1701150T (no)
RU (1) RU2365919C2 (no)
SE (1) SE528697C2 (no)
WO (1) WO2006096126A1 (no)
ZA (1) ZA200707425B (no)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3270156A1 (en) 2004-04-07 2018-01-17 Abbott Laboratories Disposable chamber for analyzing biologic fluids
SE528697C2 (sv) * 2005-03-11 2007-01-30 Hemocue Ab Volymetrisk bestämning av antalet vita blodkroppar i ett blodprov
US7796797B2 (en) * 2005-09-28 2010-09-14 Sysmex Corporation Apparatus for obtaining an image of a blood cell and method for obtaining an image of a blood cell
US7731901B2 (en) 2005-10-19 2010-06-08 Abbott Laboratories Apparatus and method for performing counts within a biologic fluid sample
SE531041C2 (sv) * 2006-07-17 2008-11-25 Hemocue Ab Räkning av trombocyter
SE530750C2 (sv) * 2006-07-19 2008-09-02 Hemocue Ab En mätapparat, en metod och ett datorprogram
SE530192C2 (sv) 2006-07-19 2008-03-25 Hemocue Ab Apparat för avbildning av prov där provhållaren är flyttbar medelst magnetisk växelverkan
US7738094B2 (en) * 2007-01-26 2010-06-15 Becton, Dickinson And Company Method, system, and compositions for cell counting and analysis
CA2684465C (en) 2007-04-20 2016-08-23 The General Hospital Corporation Methods for counting cells
SE532499C2 (sv) * 2008-01-18 2010-02-09 Hemocue Ab Metod och apparat för analys av partiklar i ett vätskeformigt prov
US8114580B2 (en) * 2009-01-13 2012-02-14 Bio-Rad Laboratories, Inc. Simulation of normal fresh blood platelets for reference control
EP2512647A2 (en) 2009-12-18 2012-10-24 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge
SE535918C2 (sv) * 2010-06-10 2013-02-19 Hemocue Ab Detektion av magnetiskt inmärkta biologiska komponenter
JP5058320B2 (ja) * 2010-09-16 2012-10-24 シスメックス株式会社 血液撮像装置および血液撮像方法
US10114020B2 (en) 2010-10-11 2018-10-30 Mbio Diagnostics, Inc. System and device for analyzing a fluidic sample
CN103282123B (zh) 2010-12-30 2015-05-06 艾博特健康公司 带有样品处理区和分析室区的生物液体分析卡式盒
CN105817276B (zh) 2011-08-24 2018-02-06 艾博特健康公司 生物流体样品分析盒
EP2758765B1 (en) * 2011-09-22 2020-08-12 FOCE Technology International B.V. Optical platelet counter method
WO2013075031A1 (en) 2011-11-16 2013-05-23 Becton, Dickinson And Company Methods and systems for detecting an analyte in a sample
JP5918988B2 (ja) * 2011-12-14 2016-05-18 公益財団法人ヒューマンサイエンス振興財団 染色キット及び染色方法
WO2014070235A1 (en) 2012-10-29 2014-05-08 Mbio Diagnostics, Inc. Biological particle identification system, cartridge and associated methods
EP2917719B1 (en) * 2012-11-09 2024-04-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Receptacle and system for optically analyzing a sample without optical lenses
JP6296457B2 (ja) 2013-01-11 2018-03-20 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 低コストの臨床現場即時アッセイデバイス
IL227276A0 (en) * 2013-07-01 2014-03-06 Parasight Ltd A method and system for obtaining a monolayer of cells, for use specifically for diagnosis
US9797899B2 (en) 2013-11-06 2017-10-24 Becton, Dickinson And Company Microfluidic devices, and methods of making and using the same
US10018640B2 (en) 2013-11-13 2018-07-10 Becton, Dickinson And Company Optical imaging system and methods for using the same
US10176363B2 (en) 2014-06-16 2019-01-08 Siemens Healthcare Diagnostics Inc. Analyzing digital holographic microscopy data for hematology applications
US10614287B2 (en) 2014-06-16 2020-04-07 Siemens Healthcare Diagnostics Inc. Virtual staining of cells in digital holographic microscopy images using general adversarial networks
CA3044748C (en) 2014-10-14 2021-10-26 Becton, Dickinson And Company Blood sample management using open cell foam
CA3172023A1 (en) 2014-10-14 2016-04-21 Becton, Dickinson And Company Blood sample management using open cell foam
ES2688270T3 (es) 2015-03-10 2018-10-31 Becton, Dickinson And Company Dispositivo de gestión de micromuestras de fluidos biológicos
US10022720B2 (en) 2015-06-12 2018-07-17 Cytochip Inc. Fluidic units and cartridges for multi-analyte analysis
US10634602B2 (en) 2015-06-12 2020-04-28 Cytochip Inc. Fluidic cartridge for cytometry and additional analysis
CN108027310B (zh) 2015-07-14 2020-12-22 芯易诊有限公司 流体盒中的体积感测
ES2857873T3 (es) 2015-09-01 2021-09-29 Becton Dickinson Co Dispositivo de filtración en profundidad para separar fases de muestras
CN105728069B (zh) * 2016-01-30 2021-01-19 深圳市安测健康信息技术有限公司 用于快速自检血液的多通道微流控芯片
CN107058455B (zh) * 2016-08-10 2021-09-17 黑龙江省农业科学院畜牧研究所 猪2细胞胚胎体积的测量方法
FR3060746B1 (fr) 2016-12-21 2019-05-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives Procede de numeration de particules dans un echantillon par imagerie sans lentille
CN111164412A (zh) * 2017-08-17 2020-05-15 雅培医护站股份有限公司 对血细胞成像的方法
WO2019083844A1 (en) 2017-10-23 2019-05-02 Cytochip Inc. DEVICES AND METHOD FOR MEASURING TARGET ANALYTES AND PARTICLES
CN107817259B (zh) * 2017-10-30 2020-05-08 中国水产科学研究院黄海水产研究所 一种海水蚶科贝类血细胞采集和超微结构观察的方法
US11327084B2 (en) 2019-09-19 2022-05-10 Invidx Corp. Joint hematology and biochemistry point-of-care testing system
US11161109B2 (en) 2019-09-19 2021-11-02 Invidx Corp. Point-of-care testing cartridge with sliding cap
GB2616840A (en) * 2022-03-18 2023-09-27 Entia Ltd A cuvette for analysing biological samples
CN114813522B (zh) * 2022-06-29 2022-10-21 深圳安侣医学科技有限公司 基于显微放大数字图像的血液细胞分析方法及***

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3906120A (en) * 1970-10-30 1975-09-16 Gen Electric Method for preparing slides for blood evaluation
US3824393A (en) * 1971-08-25 1974-07-16 American Express Invest System for differential particle counting
SE399768B (sv) * 1975-09-29 1978-02-27 Lilja Jan E Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet
US4156570A (en) * 1977-04-18 1979-05-29 Robert A. Levine Apparatus and method for measuring white blood cell and platelet concentrations in blood
US4581223A (en) * 1980-03-12 1986-04-08 Lawrence Kass Individual leukocyte determination by means of differential metachromatic dye sorption
US4420558A (en) * 1981-02-12 1983-12-13 Janssen Pharmaceutica N.V. Bright field light microscopic method of enumerating and characterizing subtypes of white blood cells and their precursors
FR2555754A1 (fr) 1983-11-28 1985-05-31 Inter Inf Procede et dispositif d'analyse automatique d'echantillons biologiques
US5188935A (en) * 1984-05-31 1993-02-23 Coulter Electronics, Inc. Reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes
US5262302A (en) * 1987-03-13 1993-11-16 Coulter Corporation Method for screening white blood cells
US4950455A (en) 1987-12-22 1990-08-21 Board Of Regents, University Of Texas System Apparatus for quantifying components in liquid samples
US5472671A (en) * 1989-04-26 1995-12-05 Nilsson; Sven-Erik Cuvette
US5585246A (en) * 1993-02-17 1996-12-17 Biometric Imaging, Inc. Method for preparing a sample in a scan capillary for immunofluorescent interrogation
CA2156752C (en) * 1993-02-25 1999-01-05 Young Ran Kim Multipurpose reagent system for rapid lysis of whole blood samples
SE504193C2 (sv) * 1995-04-21 1996-12-02 Hemocue Ab Kapillär mikrokyvett
WO1997002482A1 (en) 1995-06-30 1997-01-23 Biometric Imaging, Inc. Volumetric cell quantification method and system
EP1180676A3 (en) * 1997-05-05 2003-05-21 ChemoMetec A/S A method and a system for determination of particles in a liquid sample
US5874310A (en) * 1997-11-21 1999-02-23 Coulter International Corp. Method for differentiation of nucleated red blood cells
SE9800070D0 (sv) * 1998-01-14 1998-01-14 Hemocue Ab Blandningsmetod
US5948686A (en) * 1998-03-07 1999-09-07 Robert A. Leuine Method for performing blood cell counts
US6350613B1 (en) 1998-03-07 2002-02-26 Belton Dickinson & Co. Determination of white blood cell differential and reticulocyte counts
US6828429B1 (en) * 1999-03-26 2004-12-07 Henry M. Jackson Foundation For The Advancement Of Military Medicine Prostate-specific gene, PCGEM1, and the methods of using PCGEM1 to detect, treat, and prevent prostate cancer
EP1181529A4 (en) * 1999-04-23 2002-07-03 Surromed Inc DISPOSABLE OPTICAL CARTRIDGE WITH WC
KR20020021810A (ko) 1999-08-11 2002-03-22 야마모토 카즈모토 분석용 카트리지 및 송액 제어 장치
JP2001349825A (ja) * 2000-06-06 2001-12-21 Kowa Co キュベット・スタンド及びキュベット付きスタンド
JP2002148261A (ja) 2000-11-09 2002-05-22 Sysmex Corp 異常細胞分類計数方法
WO2002057997A1 (en) 2001-01-18 2002-07-25 Cellavision Ab Method and arrangement for segmenting white blood cells in a digital colour image
US20030133119A1 (en) * 2002-01-17 2003-07-17 Bachur Nicholas R. Rapid imaging of particles in a large fluid volume through flow cell imaging
EP1474772A4 (en) * 2002-02-14 2005-11-09 Immunivest Corp METHOD AND ALGORITHMS FOR CELL DETERMINATION IN A COST-EFFECTIVE CYTOMETER
US7797990B2 (en) 2002-06-11 2010-09-21 Chempaq A/S Disposable cartridge for characterizing particles suspended in a liquid
EP1542008B1 (en) 2002-06-24 2009-03-11 Sysmex Corporation Method of classifying and counting leucocytes
WO2005008226A1 (en) 2003-07-19 2005-01-27 Digital Bio Technology Device for counting micro particles
EP1500932A1 (en) 2003-07-21 2005-01-26 Michael J. Sommer A lysing reagent for the analysis and enumeration of residual white blood cells in leukocyte-reduced blood banking products suitable for the use in an automated clinical analyzer
SE528697C2 (sv) * 2005-03-11 2007-01-30 Hemocue Ab Volymetrisk bestämning av antalet vita blodkroppar i ett blodprov
US7067365B1 (en) * 2005-05-26 2006-06-27 United Microelectronics Corp. High-voltage metal-oxide-semiconductor devices and method of making the same
SE531233C2 (sv) * 2006-03-28 2009-01-27 Hemocue Ab Anordning och förfarande för detektion av fluorecensmärkta biologiska komponenter
SE530750C2 (sv) * 2006-07-19 2008-09-02 Hemocue Ab En mätapparat, en metod och ett datorprogram

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