NO20060706L - Inhibitorer av serinproteaser, spesielt HCV NS3-NS4A-protease - Google Patents

Inhibitorer av serinproteaser, spesielt HCV NS3-NS4A-protease

Info

Publication number
NO20060706L
NO20060706L NO20060706A NO20060706A NO20060706L NO 20060706 L NO20060706 L NO 20060706L NO 20060706 A NO20060706 A NO 20060706A NO 20060706 A NO20060706 A NO 20060706A NO 20060706 L NO20060706 L NO 20060706L
Authority
NO
Norway
Prior art keywords
compounds
disclosed
inhibitors
serine proteases
ns4a protease
Prior art date
Application number
NO20060706A
Other languages
English (en)
Norwegian (no)
Inventor
Janos Pitlik
Robert Perni
Shawn D Britt
Kevin M Cottrell
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34079432&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20060706(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20060706L publication Critical patent/NO20060706L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
NO20060706A 2003-07-18 2006-02-14 Inhibitorer av serinproteaser, spesielt HCV NS3-NS4A-protease NO20060706L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48853503P 2003-07-18 2003-07-18
PCT/US2004/023054 WO2005007681A2 (en) 2003-07-18 2004-07-16 Inhibitors of serine proteases, particularly hcv ns3-ns4a protease

Publications (1)

Publication Number Publication Date
NO20060706L true NO20060706L (no) 2006-02-14

Family

ID=34079432

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060706A NO20060706L (no) 2003-07-18 2006-02-14 Inhibitorer av serinproteaser, spesielt HCV NS3-NS4A-protease

Country Status (19)

Country Link
US (2) US7109172B2 (pt)
EP (3) EP1646642A2 (pt)
JP (2) JP4745230B2 (pt)
KR (2) KR20060052836A (pt)
CN (3) CN102020700A (pt)
AR (1) AR045916A1 (pt)
AU (2) AU2004257288A1 (pt)
BR (1) BRPI0412761A (pt)
CA (1) CA2532664A1 (pt)
HK (1) HK1098164A1 (pt)
IL (2) IL173180A0 (pt)
NO (1) NO20060706L (pt)
NZ (1) NZ544789A (pt)
PE (1) PE20050251A1 (pt)
RU (1) RU2412198C2 (pt)
TW (1) TW200523270A (pt)
UY (1) UY28423A1 (pt)
WO (1) WO2005007681A2 (pt)
ZA (1) ZA200601420B (pt)

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SG159385A1 (en) * 2002-04-11 2010-03-30 Vertex Pharma Inhibitors of serine proteases, particularly hepatitis c virus ns3 - ns4 protease
TW200510391A (en) * 2003-04-11 2005-03-16 Vertex Pharma Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
EP1646642A2 (en) * 2003-07-18 2006-04-19 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
MY148123A (en) * 2003-09-05 2013-02-28 Vertex Pharma Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
JP4685775B2 (ja) 2003-09-18 2011-05-18 バーテックス ファーマシューティカルズ インコーポレイテッド セリンプロテアーゼ、とりわけｈｃｖｎｓ３−ｎｓ４ａプロテアーゼの阻害剤
NZ546663A (en) * 2003-10-10 2010-01-29 Vertex Pharma Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
PT1677827E (pt) * 2003-10-27 2009-03-13 Vertex Pharma Associações para o tratamento do vhc
EP1711515A2 (en) * 2004-02-04 2006-10-18 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
CN101218224B (zh) 2005-05-13 2013-05-08 Viro化学制药公司 治疗或预防黄病毒感染的组合物和方法
WO2006130686A2 (en) 2005-06-02 2006-12-07 Schering Corporation Hcv protease inhibitors in combination with food
CA2611155A1 (en) * 2005-06-02 2006-12-07 Schering Corporation Pharmaceutical formulations and methods of treatment using the same
JP2009505966A (ja) * 2005-08-02 2009-02-12 バーテックス ファーマシューティカルズ インコーポレイテッド セリンプロテアーゼのインヒビター
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AP2009004960A0 (en) 2007-02-27 2009-08-31 Vertex Pharma Co-crystals and pharmaceutical compositions comprising the same
CA2679426A1 (en) * 2007-02-27 2008-09-04 Luc Farmer Inhibitors of serine proteases
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JP2013534249A (ja) 2010-08-17 2013-09-02 バーテックス ファーマシューティカルズ インコーポレイテッド フラビウイルス科ウイルス感染の処置または予防のための化合物および方法
WO2012107589A1 (en) 2011-02-11 2012-08-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment and prevention of hcv infections
WO2013016499A1 (en) 2011-07-26 2013-01-31 Vertex Pharmaceuticals Incorporated Methods for preparation of thiophene compounds
AU2012286853A1 (en) 2011-07-26 2013-05-02 Vertex Pharmaceuticals Incorporated Thiophene compounds
US20130123276A1 (en) 2011-11-14 2013-05-16 Sven Ruf Use of telaprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
NZ630805A (en) 2012-03-22 2016-01-29 Alios Biopharma Inc Pharmaceutical combinations comprising a thionucleotide analog
WO2014053533A1 (en) 2012-10-05 2014-04-10 Sanofi Use of substituted 3-heteroaroylamino-propionic acid derivatives as pharmaceuticals for prevention/treatment of atrial fibrillation
WO2014134251A1 (en) 2013-02-28 2014-09-04 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions
KR20160005334A (ko) 2013-03-14 2016-01-14 아칠리온 파르마세우티칼스 인코포레이티드 소바프레비르 제조 방법
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US9006423B2 (en) 2013-03-15 2015-04-14 Achillion Pharmaceuticals Inc. Process for making a 4-amino-4-oxobutanoyl peptide cyclic analogue, an inhibitor of viral replication, and intermediates thereof
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MX2017005467A (es) * 2014-10-27 2017-11-30 Inhibrx Lp Polipéptidos de fusión de serpina y métodos para utilizar los mismos.
US10526315B2 (en) 2016-06-21 2020-01-07 Orion Ophthalmology LLC Carbocyclic prolinamide derivatives
EA201990069A1 (ru) 2016-06-21 2019-06-28 ОРИОН ОФТАЛМОЛОДЖИ ЭлЭлСи Производные гетероциклического пролинамида
JP2022510407A (ja) 2018-12-04 2022-01-26 ブリストル－マイヤーズ スクイブ カンパニー 多重反応同位体分子種反応モニタリングによる、サンプル内検量線を用いた分析方法

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MY148123A (en) 2003-09-05 2013-02-28 Vertex Pharma Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
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NZ546663A (en) 2003-10-10 2010-01-29 Vertex Pharma Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
EP1711515A2 (en) 2004-02-04 2006-10-18 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
AR055395A1 (es) 2005-08-26 2007-08-22 Vertex Pharma Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
CA2679426A1 (en) 2007-02-27 2008-09-04 Luc Farmer Inhibitors of serine proteases

Also Published As

Publication number Publication date
AU2010257200A1 (en) 2011-01-13
CN1852920A (zh) 2006-10-25
US20060211629A1 (en) 2006-09-21
IL218698A0 (en) 2012-05-31
ZA200601420B (en) 2007-06-27
RU2006105002A (ru) 2006-08-27
AR045916A1 (es) 2005-11-16
CA2532664A1 (en) 2005-01-27
TW200523270A (en) 2005-07-16
AU2010257200B2 (en) 2011-10-20
CN101724022A (zh) 2010-06-09
CN1852920B (zh) 2010-12-15
EP2341065A2 (en) 2011-07-06
WO2005007681A2 (en) 2005-01-27
JP4745230B2 (ja) 2011-08-10
EP1646642A2 (en) 2006-04-19
KR20060052836A (ko) 2006-05-19
PE20050251A1 (es) 2005-04-13
US8691758B2 (en) 2014-04-08
AU2004257288A1 (en) 2005-01-27
WO2005007681A3 (en) 2005-06-02
BRPI0412761A (pt) 2006-09-26
CN102020700A (zh) 2011-04-20
US20050107304A1 (en) 2005-05-19
HK1098164A1 (en) 2007-07-13
IL173180A0 (en) 2006-06-11
RU2412198C2 (ru) 2011-02-20
US7109172B2 (en) 2006-09-19
JP2011116784A (ja) 2011-06-16
JP2008500265A (ja) 2008-01-10
KR20120013450A (ko) 2012-02-14
EP2368900A3 (en) 2012-07-04
AU2004257288A2 (en) 2008-06-26
NZ544789A (en) 2010-01-29
UY28423A1 (es) 2005-02-28
EP2368900A2 (en) 2011-09-28
EP2341065A3 (en) 2012-06-20

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