NO20054018L - Intranasal formulering av rotigotin - Google Patents

Intranasal formulering av rotigotin

Info

Publication number
NO20054018L
NO20054018L NO20054018A NO20054018A NO20054018L NO 20054018 L NO20054018 L NO 20054018L NO 20054018 A NO20054018 A NO 20054018A NO 20054018 A NO20054018 A NO 20054018A NO 20054018 L NO20054018 L NO 20054018L
Authority
NO
Norway
Prior art keywords
rotigotine
intranasal formulation
intranasal
moisturizing
cyclodextrin
Prior art date
Application number
NO20054018A
Other languages
English (en)
Inventor
Robert Kraemer
Original Assignee
Sanol Arznei Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanol Arznei Schwarz Gmbh filed Critical Sanol Arznei Schwarz Gmbh
Publication of NO20054018L publication Critical patent/NO20054018L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Det er beskrevet en oppfinnelse som utgjør en fiytende inttanasal farmasøytisk formulering som omfater et farmasøytisk akseptabelt syreaddisjonssalt av rotigotin og a-syklodekstrin, fortrinnsvis i form av en bufret vandig oppløsning som har en viskositet på 0,5-1,5 mm VS.
NO20054018A 2003-12-23 2005-08-30 Intranasal formulering av rotigotin NO20054018L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03029680A EP1547592A1 (en) 2003-12-23 2003-12-23 Intranasal formulation of rotigotine
PCT/EP2004/014626 WO2005063236A1 (en) 2003-12-23 2004-12-22 Intranasal formulation of rotigotine

Publications (1)

Publication Number Publication Date
NO20054018L true NO20054018L (no) 2005-08-30

Family

ID=34530709

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054018A NO20054018L (no) 2003-12-23 2005-08-30 Intranasal formulering av rotigotin

Country Status (28)

Country Link
US (1) US7683040B2 (no)
EP (2) EP1547592A1 (no)
JP (1) JP4430067B2 (no)
KR (1) KR100718760B1 (no)
CN (1) CN100374112C (no)
AT (1) ATE326961T1 (no)
AU (1) AU2004308641B2 (no)
BR (1) BRPI0407845A (no)
CA (1) CA2516400C (no)
CY (1) CY1105131T1 (no)
DE (1) DE602004000982T2 (no)
DK (1) DK1605932T3 (no)
EA (1) EA008005B1 (no)
ES (1) ES2262122T3 (no)
HK (1) HK1083596A1 (no)
HR (1) HRP20060240T3 (no)
IL (1) IL170297A (no)
IS (1) IS2310B (no)
MX (1) MXPA05008909A (no)
NO (1) NO20054018L (no)
NZ (1) NZ541875A (no)
PL (1) PL1605932T3 (no)
PT (1) PT1605932E (no)
RS (1) RS50534B (no)
SI (1) SI1605932T1 (no)
UA (1) UA79196C2 (no)
WO (1) WO2005063236A1 (no)
ZA (1) ZA200506550B (no)

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US8246980B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
US8246979B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
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EP1547592A1 (en) 2003-12-23 2005-06-29 Schwarz Pharma Ag Intranasal formulation of rotigotine
DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US20050197385A1 (en) * 2004-02-20 2005-09-08 Schwarz Pharma Ag Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) * 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
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EP2281559A1 (en) 2009-06-26 2011-02-09 UCB Pharma GmbH Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis
CA2767068C (en) 2009-12-22 2016-09-27 Ucb Pharma Gmbh Polyvinylpyrrolidone for the stabilization of a solid dispersion of the non-crystalline form of rotigotine
EP2559435A1 (en) 2011-08-19 2013-02-20 UCB Pharma GmbH Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke
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DE102012013421A1 (de) 2012-07-03 2014-01-09 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System (TTS) mit Rotigotin
WO2013075822A1 (en) 2011-11-22 2013-05-30 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermal therapeutic system (tts) with rotigotine
CN103768043B (zh) * 2012-10-22 2015-12-09 苏州药明康德新药开发股份有限公司 采用羟丙基-β-环糊精配制四氢化萘类化合物均一稳定溶液的方法
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
US10046151B2 (en) 2013-07-03 2018-08-14 Lts Lohmann Therapie-Systeme, Ag Transdermal therapeutic system with electronic component
WO2015126944A1 (en) 2014-02-18 2015-08-27 Henkin Robert I Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
ES2924899T3 (es) 2014-05-20 2022-10-11 Lts Lohmann Therapie Systeme Ag Sistema de administración transdérmica que contiene rotigotina
JP6895755B2 (ja) 2014-05-20 2021-06-30 エルテーエス ローマン テラピー−ジステーメ アーゲー 経皮送達システムにおける活性薬剤の放出を調節するための方法
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Also Published As

Publication number Publication date
CN100374112C (zh) 2008-03-12
CA2516400A1 (en) 2005-07-14
UA79196C2 (en) 2007-05-25
AU2004308641A1 (en) 2005-07-14
DE602004000982D1 (de) 2006-06-29
EP1547592A1 (en) 2005-06-29
ATE326961T1 (de) 2006-06-15
ZA200506550B (en) 2006-05-31
EP1605932B1 (en) 2006-05-24
US7683040B2 (en) 2010-03-23
KR100718760B1 (ko) 2007-05-15
PT1605932E (pt) 2006-08-31
IS8487A (is) 2006-05-26
US20070191308A1 (en) 2007-08-16
AU2004308641B2 (en) 2006-10-26
KR20060040578A (ko) 2006-05-10
CN1777422A (zh) 2006-05-24
RS50534B (sr) 2010-05-07
BRPI0407845A (pt) 2006-02-14
PL1605932T3 (pl) 2006-09-29
NZ541875A (en) 2008-08-29
EA200501159A1 (ru) 2006-02-24
IS2310B (is) 2007-11-15
JP4430067B2 (ja) 2010-03-10
IL170297A (en) 2010-06-30
HRP20060240T3 (en) 2007-05-31
DE602004000982T2 (de) 2007-05-10
EP1605932A1 (en) 2005-12-21
SI1605932T1 (sl) 2006-08-31
CA2516400C (en) 2009-10-27
WO2005063236A1 (en) 2005-07-14
ES2262122T3 (es) 2006-11-16
JP2006526004A (ja) 2006-11-16
MXPA05008909A (es) 2005-10-05
HK1083596A1 (en) 2006-07-07
DK1605932T3 (da) 2006-09-18
EA008005B1 (ru) 2007-02-27
CY1105131T1 (el) 2009-11-04

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