NO20050769L - Fremgangsmate til a innfore en 1,2-dobbelbinding i 3-okso-4-azasteroidforbindelser - Google Patents

Fremgangsmate til a innfore en 1,2-dobbelbinding i 3-okso-4-azasteroidforbindelser

Info

Publication number
NO20050769L
NO20050769L NO20050769A NO20050769A NO20050769L NO 20050769 L NO20050769 L NO 20050769L NO 20050769 A NO20050769 A NO 20050769A NO 20050769 A NO20050769 A NO 20050769A NO 20050769 L NO20050769 L NO 20050769L
Authority
NO
Norway
Prior art keywords
oxo
introducing
double bond
azasteroid compounds
azasteroid
Prior art date
Application number
NO20050769A
Other languages
English (en)
Other versions
NO329472B1 (no
Inventor
Beat W Mueller
Beat Theodor Weber
Norbert Scharer
Original Assignee
Siegfried Generics Int Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH01375/02A external-priority patent/CH704740B1/de
Priority claimed from CH00015/03A external-priority patent/CH696359A5/de
Application filed by Siegfried Generics Int Ag filed Critical Siegfried Generics Int Ag
Publication of NO20050769L publication Critical patent/NO20050769L/no
Publication of NO329472B1 publication Critical patent/NO329472B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J73/00Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J73/00Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20050769A 2002-07-16 2005-02-11 Fremgangsmate for fremstilling av 17β-substituert 4-aza-androst-1-en-3-on-forbindelser NO329472B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH12422002 2002-07-16
CH01375/02A CH704740B1 (de) 2002-08-08 2002-08-08 Verfahren zur Einführung einer 1,2-Doppelbindung bei 3-Oxo-4-azasteroidverbindungen.
CH00015/03A CH696359A5 (de) 2003-01-08 2003-01-08 Verfahren zur Einführung einer 1,2-Doppelbindung bei 3-Oxo-4-azasteroidverbindungen.
PCT/CH2003/000435 WO2004007523A1 (de) 2002-07-16 2003-07-02 Verfahren zur einführung einer 1,2-doppelbindung bei 3-oxo-4-azasteroidverbindungen

Publications (2)

Publication Number Publication Date
NO20050769L true NO20050769L (no) 2005-02-11
NO329472B1 NO329472B1 (no) 2010-10-25

Family

ID=30118655

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050769A NO329472B1 (no) 2002-07-16 2005-02-11 Fremgangsmate for fremstilling av 17β-substituert 4-aza-androst-1-en-3-on-forbindelser

Country Status (15)

Country Link
US (1) US7872135B2 (no)
EP (1) EP1523490B1 (no)
KR (1) KR20050045988A (no)
CN (1) CN1319985C (no)
AU (1) AU2003240373B2 (no)
BR (1) BR0312672A (no)
CA (1) CA2497611A1 (no)
DE (1) DE50312262D1 (no)
IL (1) IL166304A (no)
IS (1) IS7651A (no)
NO (1) NO329472B1 (no)
NZ (1) NZ537670A (no)
PL (1) PL208727B1 (no)
TW (1) TWI333957B (no)
WO (1) WO2004007523A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR070313A1 (es) * 2008-01-03 2010-03-31 Gador Sa Un procedimiento para preparar una forma solida y cristalina de dutasteride, una forma polimorfica del compuesto (forma iii) y una composicion farmaceutica que incluye dicha forma
CN101759762B (zh) * 2008-11-06 2013-03-20 天津金耀集团有限公司 4ad在制备度他雄胺中的应用
HU230730B1 (hu) 2011-06-30 2017-12-28 Richter Gedeon Nyrt Eljárás (5alfa,17béta)-N-[2,5-bisz-(trifluormetil)-fenil]-3-oxo-4-aza-5-androszt-1-én-17-karbonsavamid előállítására

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0040177B1 (de) * 1980-05-13 1983-07-20 Ciba-Geigy Ag Verfahren zur Herstellung von Alkenylbenzol- oder -naphthalincarbonsäurederivaten
US4760071A (en) * 1984-02-27 1988-07-26 Merck & Co., Inc. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
NZ225100A (en) 1987-06-29 1991-09-25 Merck & Co Inc Reaction of steroids (including 4-azasteroids) with a silylating agent in the presence of a quinone to introduce a delta' double bond and silylated intermediates
US5021575A (en) * 1989-11-13 1991-06-04 Merck & Co., Inc. Method for introducing a 1,2 double bond into azasteroids
US5091534A (en) * 1990-08-27 1992-02-25 Merck & Co., Inc. Trialkylsilyl trifluoromethanesulfonate mediated α-methylenic carbon functionalization of 4-AZA-5α-androstan-3-one steroids
DE4444738A1 (de) * 1994-12-15 1996-06-20 Bayer Ag Verfahren zur Herstellung von Carbonylverbindungen durch katalysierte Oxidation von Olefinen und in Mikroemulsionen angeordnete Katalysatoren

Also Published As

Publication number Publication date
PL208727B1 (pl) 2011-06-30
NZ537670A (en) 2006-05-26
NO329472B1 (no) 2010-10-25
EP1523490A1 (de) 2005-04-20
US7872135B2 (en) 2011-01-18
AU2003240373A1 (en) 2004-02-02
US20060100434A1 (en) 2006-05-11
IS7651A (is) 2005-01-14
PL374712A1 (en) 2005-10-31
BR0312672A (pt) 2005-04-26
EP1523490B1 (de) 2009-12-23
IL166304A (en) 2011-11-30
TW200406420A (en) 2004-05-01
AU2003240373B2 (en) 2007-09-20
WO2004007523A1 (de) 2004-01-22
CA2497611A1 (en) 2004-01-22
DE50312262D1 (de) 2010-02-04
TWI333957B (en) 2010-12-01
CN1319985C (zh) 2007-06-06
IL166304A0 (en) 2006-01-15
CN1668632A (zh) 2005-09-14
KR20050045988A (ko) 2005-05-17

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