NO20041909L - Nye forbindelser og sammensetninger som katepsin S-inhibitorer - Google Patents
Nye forbindelser og sammensetninger som katepsin S-inhibitorerInfo
- Publication number
- NO20041909L NO20041909L NO20041909A NO20041909A NO20041909L NO 20041909 L NO20041909 L NO 20041909L NO 20041909 A NO20041909 A NO 20041909A NO 20041909 A NO20041909 A NO 20041909A NO 20041909 L NO20041909 L NO 20041909L
- Authority
- NO
- Norway
- Prior art keywords
- cathepsin
- inhibitors
- compositions
- new compounds
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33260501P | 2001-11-14 | 2001-11-14 | |
PCT/US2002/036396 WO2003042197A1 (fr) | 2001-11-14 | 2002-11-14 | Nouveaux composes et compositions jouant le role d'inhibiteurs de cathepsine s |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20041909L true NO20041909L (no) | 2004-05-10 |
Family
ID=23298977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20041909A NO20041909L (no) | 2001-11-14 | 2004-05-10 | Nye forbindelser og sammensetninger som katepsin S-inhibitorer |
Country Status (21)
Country | Link |
---|---|
US (3) | US6977256B2 (fr) |
EP (1) | EP1446392A1 (fr) |
JP (1) | JP2005514353A (fr) |
KR (1) | KR20050044497A (fr) |
CN (1) | CN1324018C (fr) |
BR (1) | BR0214104A (fr) |
CA (1) | CA2467391A1 (fr) |
CO (1) | CO5640128A2 (fr) |
HK (1) | HK1073840A1 (fr) |
HR (1) | HRP20040426A2 (fr) |
HU (1) | HUP0401906A3 (fr) |
IL (1) | IL161950A0 (fr) |
MA (1) | MA27140A1 (fr) |
MX (1) | MXPA04004450A (fr) |
NO (1) | NO20041909L (fr) |
NZ (1) | NZ532167A (fr) |
PL (1) | PL372105A1 (fr) |
RU (1) | RU2004117877A (fr) |
WO (1) | WO2003042197A1 (fr) |
YU (1) | YU34604A (fr) |
ZA (1) | ZA200403602B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0212535A (pt) * | 2001-09-14 | 2004-10-19 | Aventis Pharma Inc | Compostos e composições como inibidores de catepsina |
CN1324018C (zh) * | 2001-11-14 | 2007-07-04 | 安万特药物公司 | 作为组织蛋白酶s抑制剂的寡肽以及含有它们的组合物 |
JP2005526830A (ja) * | 2002-04-16 | 2005-09-08 | アクシス・ファーマシューティカルズ・インコーポレイテッド | ヘテロアリール及び不飽和ヘテロシクロアルキルマグネシウム試薬の製造方法及び使用 |
CN1708293A (zh) | 2002-09-24 | 2005-12-14 | 诺瓦提斯公司 | 治疗脱髓鞘疾病的鞘氨醇-1-磷酸受体激动剂 |
WO2009087379A2 (fr) | 2008-01-09 | 2009-07-16 | Amura Therapeutics Limited | Composés |
CA2728514C (fr) | 2008-06-20 | 2020-08-11 | Novartis Ag | Compositions pediatriques pour le traitement de la sclerose en plaques |
WO2011069149A2 (fr) * | 2009-12-04 | 2011-06-09 | Dcb-Usa Llc | Inhibiteurs de la cathépsine s |
Family Cites Families (70)
Publication number | Priority date | Publication date | Assignee | Title |
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US5874424A (en) | 1995-12-20 | 1999-02-23 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β converting enzyme |
DE3606480A1 (de) | 1986-02-28 | 1987-09-03 | Behringwerke Ag | Oligopeptidylnitrilderivate, diese enthaltende mittel, verfahren zu ihrer herstellung und ihre verwendung |
US5055451A (en) | 1986-12-22 | 1991-10-08 | Syntex Inc. | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors |
GB8809316D0 (en) | 1987-05-11 | 1988-05-25 | Ici America Inc | Heterocyclic ketones |
JPS63303868A (ja) | 1987-06-03 | 1988-12-12 | Oki Electric Ind Co Ltd | 誘電体セラミックスの製造方法 |
DE3827415A1 (de) | 1988-08-12 | 1990-02-15 | Behringwerke Ag | Peptidderivate, verfahren zu ihrer herstellung und ihre verwendung |
EP0376012A3 (fr) | 1988-12-27 | 1992-05-06 | American Cyanamid Company | Inhibiteurs de la rénine |
WO1990012005A1 (fr) | 1989-04-13 | 1990-10-18 | Japan Tobacco Inc. | Nouveaux derives aminoacides possedant une activite d'inhibiteur de la prolylendopeptidase |
DK0536399T3 (da) | 1990-06-07 | 1996-06-03 | Zeria Pharm Co Ltd | Hidtil ukendt arylalkanonylaminderivat og lægemiddel indeholdende samme |
JPH06192199A (ja) | 1992-12-25 | 1994-07-12 | Mitsubishi Kasei Corp | ケトン誘導体 |
CA2111930A1 (fr) | 1992-12-25 | 1994-06-26 | Ryoichi Ando | Derives d'aminocetones |
ZA945719B (en) | 1993-08-09 | 1996-02-01 | Lilly Co Eli | Identification and use of protease inhibitors |
CZ134296A3 (en) | 1993-11-09 | 1996-12-11 | Merck & Co Inc | Piperidine, pyrrolidine and hexahydro-1h-azepine derivatives, process of their preparation and pharmaceutical compositions containing thereof |
IL111785A0 (en) | 1993-12-03 | 1995-01-24 | Ferring Bv | Dp-iv inhibitors and pharmaceutical compositions containing them |
US5486623A (en) | 1993-12-08 | 1996-01-23 | Prototek, Inc. | Cysteine protease inhibitors containing heterocyclic leaving groups |
US5714484A (en) | 1993-12-08 | 1998-02-03 | Prototek, Inc. | α-(1,3-dicarbonylenol ether) methyl ketones as cysteine protease inhibitors |
JPH07228529A (ja) | 1994-02-17 | 1995-08-29 | Zeria Pharmaceut Co Ltd | コリンエステラーゼ賦活剤 |
WO1995024382A1 (fr) | 1994-03-10 | 1995-09-14 | G.D. Searle & Co. | Derives de la l-n6-(1-iminoethyl)lysine utiles comme inhibiteurs de la synthetase generant de l'oxyde nitrique |
US5847135A (en) | 1994-06-17 | 1998-12-08 | Vertex Pharmaceuticals, Incorporated | Inhibitors of interleukin-1β converting enzyme |
US5498616A (en) | 1994-11-04 | 1996-03-12 | Cephalon, Inc. | Cysteine protease and serine protease inhibitors |
US6015791A (en) | 1994-11-21 | 2000-01-18 | Cortech Inc. | Serine protease inhibitors-cycloheptane derivatives |
US5691368A (en) | 1995-01-11 | 1997-11-25 | Hoechst Marion Roussel, Inc. | Substituted oxazolidine calpain and/or cathepsin B inhibitors |
NZ305626A (en) | 1995-03-24 | 2000-01-28 | Axys Pharm Inc | Reversible protease inhibitors |
TW438591B (en) * | 1995-06-07 | 2001-06-07 | Arris Pharm Corp | Reversible cysteine protease inhibitors |
US6022861A (en) | 1995-06-07 | 2000-02-08 | Cor Therapeutics, Inc. | Ketoheterocyclic inhibitors of factor Xa |
US6069130A (en) | 1995-06-07 | 2000-05-30 | Cor Therapeutics, Inc. | Ketoheterocyclic inhibitors of factor Xa |
EP0840614A1 (fr) | 1995-06-13 | 1998-05-13 | Sanofi Winthrop, Inc. | Inhibiteurs de la calpaine destines au traitement de maladies neurodegeneratives |
US6124333A (en) | 1995-06-22 | 2000-09-26 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
DK0871454T3 (da) | 1995-07-17 | 2004-03-22 | Cephalon Inc | Phosphorholdige inhibitorer af cystein- og serinprotease |
ES2293651T3 (es) | 1995-11-28 | 2008-03-16 | Cephalon, Inc. | Inhibidores de cisteina y serina proteasas derivados de aminoacidos d. |
JP2002514162A (ja) | 1996-07-08 | 2002-05-14 | デュポン ファーマシューティカルズ カンパニー | Xa因子阻害薬およびトロンビン阻害薬としてのアミジノインドール類、アミジノアゾール類、およびそれらの類似体 |
AU3359697A (en) | 1996-07-08 | 1998-02-02 | Yamanouchi Pharmaceutical Co., Ltd. | Bone resorption inhibitors |
DZ2285A1 (fr) | 1996-08-08 | 2002-12-25 | Smithkline Beecham Corp | Inhibiteurs de protéase de la cystéine. |
KR100318804B1 (ko) | 1996-08-28 | 2002-01-04 | 시오노 요시히코 | 티아졸릴-알라닌 잔기를 갖는 신규한 펩티드 유도체 |
EP0923535A4 (fr) | 1996-08-28 | 2001-01-10 | Smithkline Beecham Corp | Inhibiteurs de cysteine protease |
UA56197C2 (uk) | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
GB9624817D0 (en) | 1996-11-28 | 1997-01-15 | British Biotech Pharm | Metalloproteinase inhibitors |
US6004933A (en) | 1997-04-25 | 1999-12-21 | Cortech Inc. | Cysteine protease inhibitors |
GB9723407D0 (en) | 1997-11-05 | 1998-01-07 | Ciba Geigy Ag | Organic compounds |
DE69841871D1 (en) | 1997-11-05 | 2010-10-14 | Novartis Ag | Dipeptide nitrile |
US6114310A (en) | 1998-01-23 | 2000-09-05 | Microcide Pharmaceuticals, Inc. | Efflux pump inhibitors |
WO2000032216A1 (fr) * | 1998-06-03 | 2000-06-08 | Cortech Inc. | Peptoide et non-peptoide contenant des exadiaoles alpha-ceto et utilises comme inhibiteurs de protease serine |
US5998390A (en) | 1998-09-28 | 1999-12-07 | The Research Foundation Of State University Of New York | Combination of bisphosphonate and tetracycline |
JP2002537293A (ja) | 1999-02-20 | 2002-11-05 | アストラゼネカ アクチボラグ | カテプシンlおよび/またはカテプシンsの阻害剤としてのアセタミドアセトニトリル誘導体 |
GB9903861D0 (en) | 1999-02-20 | 1999-04-14 | Zeneca Ltd | Chemical compounds |
JP2002537294A (ja) | 1999-02-20 | 2002-11-05 | アストラゼネカ アクチボラグ | カテプシンl及びカテプシンsの阻害剤としてのジ−及びトリペプチドニトリル誘導体 |
WO2000051998A1 (fr) | 1999-03-02 | 2000-09-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Composes utiles en tant qu'inhibiteurs reversibles de la cathepsine s |
TW200404789A (en) | 1999-03-15 | 2004-04-01 | Axys Pharm Inc | Novel compounds and compositions as protease inhibitors |
EE200100487A (et) | 1999-03-15 | 2003-02-17 | Axys Pharmaceuticals, Inc. | Uudsed ühendid ja kompositsioonid proteaasiinhibiitoritena |
EP1159260A1 (fr) | 1999-03-15 | 2001-12-05 | Axys Pharmaceuticals, Inc. | Composes et compositions utilises comme inhibiteurs de protease |
GB9907683D0 (en) | 1999-04-06 | 1999-05-26 | Synphar Lab Inc | Substituted azetidin-2-ones as cysteine protease inhibitors |
GB9911417D0 (en) | 1999-05-18 | 1999-07-14 | Peptide Therapeutics Ltd | Furanone derivatives as inhibitors of cathepsin s |
JP2001011037A (ja) | 1999-07-01 | 2001-01-16 | Kissei Pharmaceut Co Ltd | シクロアルカンカルボン酸アミド誘導体 |
EP1204652B1 (fr) | 1999-07-30 | 2006-05-17 | Boehringer Ingelheim Pharmaceuticals Inc. | Nouveaux composes de derives de succinate utilises comme inhibiteurs des cysteine proteases |
GB9917909D0 (en) | 1999-07-31 | 1999-09-29 | Synphar Lab Inc | Cysteine protease inhibitors |
JP2001055366A (ja) | 1999-08-12 | 2001-02-27 | Kissei Pharmaceut Co Ltd | ビアリール酢酸アミド誘導体 |
HUP0302380A2 (hu) | 1999-09-13 | 2004-03-01 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cisztein-proteázok reverzibilis inhibitoraiként alkalmazható új spiroheterociklusos vegyületek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
AU7490900A (en) | 1999-09-16 | 2001-04-17 | Axys Pharmaceuticals, Inc. | Chemical compounds and compositions and their use as cathepsin s inhibitors |
GB9925264D0 (en) | 1999-10-26 | 1999-12-29 | Zeneca Ltd | Chemical compounds |
HU227039B1 (en) | 2000-01-25 | 2010-05-28 | Egis Gyogyszergyar Nyilvanosan | New process for the production of quetiapine and intermediates therefor |
GB0003111D0 (en) | 2000-02-10 | 2000-03-29 | Novartis Ag | Organic compounds |
PT1362052E (pt) | 2001-01-17 | 2007-04-30 | Amura Therapeutics Ltd | Inibidores de cruzipaína e de outras proteases de cisteína |
US7132449B2 (en) | 2001-01-17 | 2006-11-07 | Amura Therapeutics Limited | Inhibitors of cruzipain and other cysteine proteases |
CA2435117A1 (fr) | 2001-01-17 | 2002-07-25 | Amura Therapeutics Limited | 2-carbonylaminocetones cycliques, inhibiteurs de la cruzipain et autres cysteine proteases |
JPWO2002096892A1 (ja) | 2001-05-31 | 2004-09-09 | 小野薬品工業株式会社 | オキサジアゾール誘導体化合物およびその化合物を有効成分とする薬剤 |
EA007335B1 (ru) * | 2001-06-01 | 2006-08-25 | Эксис Фармасьютикалз, Инк. | Новые соединения и композиции как ингибиторы катепсина |
US6982263B2 (en) | 2001-06-08 | 2006-01-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Nitriles useful as reversible inhibitors of cysteine proteases |
BR0212535A (pt) * | 2001-09-14 | 2004-10-19 | Aventis Pharma Inc | Compostos e composições como inibidores de catepsina |
CN1324018C (zh) * | 2001-11-14 | 2007-07-04 | 安万特药物公司 | 作为组织蛋白酶s抑制剂的寡肽以及含有它们的组合物 |
-
2002
- 2002-11-14 CN CNB028226879A patent/CN1324018C/zh not_active Expired - Fee Related
- 2002-11-14 CA CA002467391A patent/CA2467391A1/fr not_active Abandoned
- 2002-11-14 JP JP2003544033A patent/JP2005514353A/ja active Pending
- 2002-11-14 PL PL02372105A patent/PL372105A1/xx not_active Application Discontinuation
- 2002-11-14 YU YU34604A patent/YU34604A/sh unknown
- 2002-11-14 NZ NZ532167A patent/NZ532167A/en unknown
- 2002-11-14 US US10/294,526 patent/US6977256B2/en not_active Expired - Fee Related
- 2002-11-14 KR KR1020047007466A patent/KR20050044497A/ko not_active Application Discontinuation
- 2002-11-14 WO PCT/US2002/036396 patent/WO2003042197A1/fr active Application Filing
- 2002-11-14 BR BR0214104-3A patent/BR0214104A/pt not_active IP Right Cessation
- 2002-11-14 MX MXPA04004450A patent/MXPA04004450A/es not_active Application Discontinuation
- 2002-11-14 RU RU2004117877/04A patent/RU2004117877A/ru not_active Application Discontinuation
- 2002-11-14 EP EP02792253A patent/EP1446392A1/fr not_active Withdrawn
- 2002-11-14 IL IL16195002A patent/IL161950A0/xx unknown
- 2002-11-14 HU HU0401906A patent/HUP0401906A3/hu unknown
-
2004
- 2004-04-06 MA MA27611A patent/MA27140A1/fr unknown
- 2004-05-10 NO NO20041909A patent/NO20041909L/no not_active Application Discontinuation
- 2004-05-11 ZA ZA200403602A patent/ZA200403602B/xx unknown
- 2004-05-12 CO CO04043885A patent/CO5640128A2/es unknown
- 2004-05-13 HR HR20040426A patent/HRP20040426A2/hr not_active Application Discontinuation
-
2005
- 2005-06-24 US US11/166,829 patent/US7226921B2/en not_active Expired - Fee Related
- 2005-07-25 HK HK05106311A patent/HK1073840A1/xx not_active IP Right Cessation
-
2007
- 2007-04-26 US US11/740,414 patent/US20070203138A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MXPA04004450A (es) | 2004-08-11 |
US20070203138A1 (en) | 2007-08-30 |
NZ532167A (en) | 2006-11-30 |
PL372105A1 (en) | 2005-07-11 |
US20030199506A1 (en) | 2003-10-23 |
HK1073840A1 (en) | 2005-10-21 |
CN1324018C (zh) | 2007-07-04 |
US6977256B2 (en) | 2005-12-20 |
WO2003042197A1 (fr) | 2003-05-22 |
HUP0401906A2 (hu) | 2004-12-28 |
JP2005514353A (ja) | 2005-05-19 |
KR20050044497A (ko) | 2005-05-12 |
CO5640128A2 (es) | 2006-05-31 |
ZA200403602B (en) | 2005-08-31 |
MA27140A1 (fr) | 2005-01-03 |
CA2467391A1 (fr) | 2003-05-22 |
IL161950A0 (en) | 2005-11-20 |
RU2004117877A (ru) | 2006-01-10 |
US7226921B2 (en) | 2007-06-05 |
YU34604A (sh) | 2006-08-17 |
CN1585757A (zh) | 2005-02-23 |
HUP0401906A3 (en) | 2008-07-28 |
HRP20040426A2 (en) | 2004-10-31 |
EP1446392A1 (fr) | 2004-08-18 |
US20050267044A1 (en) | 2005-12-01 |
BR0214104A (pt) | 2004-09-28 |
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