NO2002010I2 - Ertapenem - Google Patents

Ertapenem

Info

Publication number: NO2002010I2
Authority: NO; Norway
Prior art keywords: ertapenem
Prior art date: 1992-02-04

Application number

NO2002010C

Other languages

English (en)

Other versions

NO2002010I1 (no

Original Assignee

Astrazeneca Uk Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-04

Filing date

2002-10-09

Publication date

2005-03-11

2002-10-09 Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd

2002-10-09 Publication of NO2002010I1 publication Critical patent/NO2002010I1/no

2005-03-11 Publication of NO2002010I2 publication Critical patent/NO2002010I2/no

Links

JUZNIMUFDBIJCM-ANEDZVCMSA-N Invanz Chemical compound O=C([C@H]1NC[C@H](C1)SC=1[C@H](C)[C@@H]2[C@H](C(N2C=1C(O)=O)=O)[C@H](O)C)NC1=CC=CC(C(O)=O)=C1 JUZNIMUFDBIJCM-ANEDZVCMSA-N 0.000 title 1
229960002770 ertapenem Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO2002010C 1992-02-04 2002-10-09 Ertapenem NO2002010I2 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929202298A GB9202298D0 (en)	1992-02-04	1992-02-04	Antibiotic compounds
PCT/GB1993/000217 WO1993015078A1 (en)	1992-02-04	1993-02-02	Carbapenems containing a carboxy substituted phenyl group, processes for their preparation, intermediates and use as antibiotics

Publications (2)

Publication Number	Publication Date
NO2002010I1 NO2002010I1 (no)	2002-10-09
NO2002010I2 true NO2002010I2 (no)	2005-03-11

Family

ID=10709764

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO933530A NO304315B1 (no)	1992-02-04	1993-10-01	Karbapenemer inneholdene en karboksysubstituert fenylgruppe, mellomprodukter for fremstilling derav, og farmas°ytiske preparater inneholdende dem
NO2002010C NO2002010I2 (no)	1992-02-04	2002-10-09	Ertapenem

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NO933530A NO304315B1 (no)	1992-02-04	1993-10-01	Karbapenemer inneholdene en karboksysubstituert fenylgruppe, mellomprodukter for fremstilling derav, og farmas°ytiske preparater inneholdende dem

Country Status (35)

Country	Link
US (7)	US5478820A (no)
EP (1)	EP0579826B1 (no)
JP (1)	JP2730600B2 (no)
KR (1)	KR100200986B1 (no)
CN (1)	CN1036006C (no)
AP (1)	AP398A (no)
AT (1)	ATE173262T1 (no)
AU (1)	AU668133B2 (no)
CA (1)	CA2106370C (no)
CZ (1)	CZ286878B6 (no)
DE (2)	DE10299041I2 (no)
DK (1)	DK0579826T3 (no)
ES (1)	ES2123654T3 (no)
FI (1)	FI104074B1 (no)
GB (2)	GB9202298D0 (no)
GE (1)	GEP20022694B (no)
HK (1)	HK1013998A1 (no)
HR (1)	HRP930103B1 (no)
HU (3)	HU213675B (no)
IL (1)	IL104588A (no)
LU (1)	LU90970I2 (no)
MY (1)	MY111685A (no)
NL (1)	NL300104I2 (no)
NO (2)	NO304315B1 (no)
NZ (2)	NZ272038A (no)
PL (3)	PL174936B1 (no)
RU (1)	RU2117659C1 (no)
SG (1)	SG48817A1 (no)
SI (1)	SI9300056B (no)
SK (1)	SK280890B6 (no)
TW (1)	TW408124B (no)
UA (1)	UA44885C2 (no)
WO (1)	WO1993015078A1 (no)
YU (1)	YU48998B (no)
ZA (1)	ZA93453B (no)

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CN104703986A (zh)	2012-10-12	2015-06-10	桑多斯股份公司	厄他培南中间体的制备
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GB9107341D0 (en) *	1991-04-08	1991-05-22	Ici Plc	Antibiotic compounds
NO302475B1 (no) *	1991-06-04	1998-03-09	Sankyo Co	1-metylkarbapenemderivater og farmasöytisk preparat inneholdende disse
ZA929008B (en) *	1991-12-13	1993-05-21	Bristol Myers Squibb Co	Piperazinyl- and piperidinyl-cyclohexanols.
GB9202298D0 (en) *	1992-02-04	1992-03-18	Ici Plc	Antibiotic compounds
GB9304156D0 (en) *	1992-03-26	1993-04-21	Zeneca Ltd	Antibiotic compounds
CA2091309A1 (en) *	1992-03-26	1993-09-27	Frederic H. Jung	Antibiotic compounds
CA2099817A1 (en) *	1992-07-21	1994-01-22	Frederic H. Jung	Antibiotic compounds
CA2099818A1 (en) *	1992-07-21	1994-01-22	Frederic H. Jung	Antibiotic compounds
CA2099811A1 (en) *	1992-07-21	1994-01-22	Frederic H. Jung	Antibiotic compounds
CA2106141A1 (en) *	1992-09-28	1994-03-29	Michael J. Betts	Antibiotic compounds

1992
- 1992-02-04 GB GB929202298A patent/GB9202298D0/en active Pending
1993
- 1993-01-12 GB GB939300456A patent/GB9300456D0/en active Pending
- 1993-01-21 AP APAP/P/1993/000480A patent/AP398A/en active
- 1993-01-21 ZA ZA93453A patent/ZA93453B/xx unknown
- 1993-01-27 MY MYPI93000120A patent/MY111685A/en unknown
- 1993-01-29 YU YU5493A patent/YU48998B/sh unknown
- 1993-02-02 SG SG1996001979A patent/SG48817A1/en unknown
- 1993-02-02 US US08/129,056 patent/US5478820A/en not_active Expired - Lifetime
- 1993-02-02 PL PL93317448A patent/PL174936B1/pl unknown
- 1993-02-02 EP EP93914514A patent/EP0579826B1/en not_active Expired - Lifetime
- 1993-02-02 HU HU9302777A patent/HU213675B/hu unknown
- 1993-02-02 JP JP5513073A patent/JP2730600B2/ja not_active Expired - Lifetime
- 1993-02-02 HU HU9302777D patent/HUT66514A/hu unknown
- 1993-02-02 CZ CZ19932067A patent/CZ286878B6/cs not_active IP Right Cessation
- 1993-02-02 DE DE2002199041 patent/DE10299041I2/de active Active
- 1993-02-02 AT AT93914514T patent/ATE173262T1/de active
- 1993-02-02 NZ NZ272038A patent/NZ272038A/en not_active IP Right Cessation
- 1993-02-02 KR KR1019930702942A patent/KR100200986B1/ko not_active IP Right Cessation
- 1993-02-02 DK DK93914514T patent/DK0579826T3/da active
- 1993-02-02 CA CA002106370A patent/CA2106370C/en not_active Expired - Lifetime
- 1993-02-02 SI SI9300056A patent/SI9300056B/sl unknown
- 1993-02-02 AU AU34574/93A patent/AU668133B2/en not_active Expired
- 1993-02-02 RU RU93058253/04A patent/RU2117659C1/ru active
- 1993-02-02 WO PCT/GB1993/000217 patent/WO1993015078A1/en active IP Right Grant
- 1993-02-02 PL PL93317447A patent/PL174601B1/pl unknown
- 1993-02-02 NZ NZ246917A patent/NZ246917A/en not_active IP Right Cessation
- 1993-02-02 PL PL93300768A patent/PL174649B1/pl unknown
- 1993-02-02 ES ES93914514T patent/ES2123654T3/es not_active Expired - Lifetime
- 1993-02-02 DE DE69322007T patent/DE69322007T2/de not_active Expired - Lifetime
- 1993-02-02 SK SK1063-93A patent/SK280890B6/sk active Protection Beyond IP Right Term
- 1993-02-02 IL IL10458893A patent/IL104588A/en active Protection Beyond IP Right Term
- 1993-02-03 FI FI930474A patent/FI104074B1/fi not_active IP Right Cessation
- 1993-02-03 HR HR9202298.7A patent/HRP930103B1/xx not_active IP Right Cessation
- 1993-02-04 CN CN93101472A patent/CN1036006C/zh not_active Expired - Lifetime
- 1993-02-09 TW TW082100868A patent/TW408124B/zh not_active IP Right Cessation
- 1993-06-18 UA UA93003121A patent/UA44885C2/uk unknown
- 1993-10-01 NO NO933530A patent/NO304315B1/no not_active IP Right Cessation
1995
- 1995-06-05 US US08/462,037 patent/US5652233A/en not_active Expired - Lifetime
- 1995-06-14 HU HU95P/P00201P patent/HU211840A9/hu active Protection Beyond IP Right Term
1997
- 1997-04-03 US US08/833,056 patent/US5856321A/en not_active Expired - Lifetime
1998
- 1998-10-08 US US09/168,293 patent/US6187804B1/en not_active Expired - Lifetime
- 1998-12-24 HK HK98115416A patent/HK1013998A1/xx not_active IP Right Cessation
2001
- 2001-02-13 US US09/781,556 patent/US6521612B2/en not_active Expired - Fee Related
- 2001-08-31 GE GE4468A patent/GEP20022694B/en unknown
2002
- 2002-10-09 LU LU90970C patent/LU90970I2/fr unknown
- 2002-10-09 NO NO2002010C patent/NO2002010I2/no unknown
- 2002-10-18 NL NL300104C patent/NL300104I2/nl unknown
- 2002-11-14 US US10/293,561 patent/US7041836B2/en not_active Expired - Fee Related
2005
- 2005-05-11 US US11/126,331 patent/US7342005B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
RU2117659C1 (ru)	1998-08-20
HK1013998A1 (en)	1999-09-17
UA44885C2 (uk)	2002-03-15
US5478820A (en)	1995-12-26
AP398A (en)	1995-08-29
YU5493A (sh)	1996-05-20
KR100200986B1 (ko)	1999-06-15
ZA93453B (en)	1993-08-05
US6187804B1 (en)	2001-02-13
IL104588A (en)	1999-03-12
PL174649B1 (pl)	1998-08-31
JP2730600B2 (ja)	1998-03-25
FI930474A0 (fi)	1993-02-03
HRP930103A2 (en)	1994-12-31
NL300104I1 (nl)	2002-12-02
IL104588A0 (en)	1993-06-10
US20050209212A1 (en)	2005-09-22
HU211840A9 (en)	1995-12-28
DE69322007T2 (de)	1999-04-01
NZ272038A (en)	1997-07-27
US6521612B2 (en)	2003-02-18
FI104074B (fi)	1999-11-15
CN1079224A (zh)	1993-12-08
HUT64764A (en)	1994-02-28
LU90970I2 (fr)	2002-12-09
CN1036006C (zh)	1997-10-01
NL300104I2 (nl)	2003-02-03
PL174936B1 (pl)	1998-10-30
US5856321A (en)	1999-01-05
ES2123654T3 (es)	1999-01-16
AU668133B2 (en)	1996-04-26
CA2106370C (en)	2003-11-25
GB9300456D0 (en)	1993-03-03
US7342005B2 (en)	2008-03-11
FI104074B1 (fi)	1999-11-15
YU48998B (sh)	2003-04-30
US7041836B2 (en)	2006-05-09
ATE173262T1 (de)	1998-11-15
AP9300480A0 (en)	1993-01-31
DK0579826T3 (da)	1999-07-26
HU213675B (en)	1997-09-29
DE10299041I2 (de)	2003-06-12
NO933530D0 (no)	1993-10-01
JPH06506704A (ja)	1994-07-28
NO2002010I1 (no)	2002-10-09
MY111685A (en)	2000-11-30
SI9300056B (sl)	2000-02-29
SK280890B6 (sk)	2000-09-12
DE10299041I1 (de)	2003-02-20
EP0579826B1 (en)	1998-11-11
NO304315B1 (no)	1998-11-30
SG48817A1 (en)	1998-05-18
SI9300056A (en)	1993-09-30
NZ246917A (en)	1995-09-26
US5652233A (en)	1997-07-29
EP0579826A1 (en)	1994-01-26
FI930474A (fi)	1993-08-05
HUT66514A (en)	1994-12-28
HU9302777D0 (en)	1993-12-28
HRP930103B1 (en)	1999-12-31
CZ286878B6 (en)	2000-07-12
GEP20022694B (en)	2002-05-10
US20030144264A1 (en)	2003-07-31
WO1993015078A1 (en)	1993-08-05
DE69322007D1 (de)	1998-12-17
US20020042408A1 (en)	2002-04-11
SK106393A3 (en)	1994-04-06
CZ206793A3 (en)	1994-04-13
PL174601B1 (pl)	1998-08-31
NO933530L (no)	1993-10-04
CA2106370A1 (en)	1993-08-05
TW408124B (en)	2000-10-11
AU3457493A (en)	1993-09-01
GB9202298D0 (en)	1992-03-18

Publication	Publication Date	Title
NO2002010I1 (no)	2002-10-09	Ertapenem
FI920650A (fi)	1993-08-15	Diversiteettiboosteri
FIU920242U0 (fi)	1992-03-23	Skyddsmask
FI933241A (fi)	1994-01-21	Manoeverenhet
FI932393A0 (fi)	1993-05-26	Korttidsfoerraod foer sedlar
FI933816A0 (fi)	1993-09-01	Understaell foer raelsfordon
FI931227A (fi)	1993-09-20	Polyetenisoleringskomposition
FI930779A (fi)	1994-05-31	Insulationsmaterial
FI930572A (fi)	1993-08-14	Utvidgat televisionssystem
FIU920674U0 (fi)	1992-11-11	Sportsko
FI934404A (fi)	1994-04-10	Saekerhetskoppling avsedd foer flerfoergrenade elkopplingsanordningar
FI101198B1 (fi)	1998-05-15	Kaasunaamari
FI920977A (fi)	1993-09-06	Foerflyttbar moebel foer hushaoll
FI934292A (fi)	1994-04-02	Mobiltelefon
FI626U1 (fi)	1993-03-24	Expansionskaerl foer nivaoskillnadsmaetare
FI306U1 (fi)	1992-10-08	Yttertakelement
PT8484T (pt)	1993-07-30	Sacarrolhas aperfeicoado
FI663U1 (fi)	1993-04-14	Faestningsmedel foer en smygmonteringskran
FI569U1 (fi)	1993-03-08	Stockfoerband
FI529U1 (fi)	1993-02-17	Saeng
FI458U1 (fi)	1993-01-14	Ograesbekaempningsanordning
FI93U1 (fi)	1992-04-28	Balkongfastsaettningsenhet
FI32U1 (fi)	1992-02-25	Stoedkonstruktion foer mutterhaol
FI159U1 (fi)	1992-07-09	Centrerhylsa
FI545U1 (fi)	1993-02-19	Ljusstake