NO20015379D0 - Indolinderivater som progesteronantagonister - Google Patents

Indolinderivater som progesteronantagonister

Info

Publication number
NO20015379D0
NO20015379D0 NO20015379A NO20015379A NO20015379D0 NO 20015379 D0 NO20015379 D0 NO 20015379D0 NO 20015379 A NO20015379 A NO 20015379A NO 20015379 A NO20015379 A NO 20015379A NO 20015379 D0 NO20015379 D0 NO 20015379D0
Authority
NO
Norway
Prior art keywords
indoline derivatives
progesterone antagonists
antagonists
progesterone
benign
Prior art date
Application number
NO20015379A
Other languages
English (en)
Other versions
NO20015379L (no
Inventor
Andrew Fensome
Lori L Miller
John W Ullrich
Reinhold H W Bender
Puwen Zhang
Jay E Wrobel
Lin Zhi
Todd K Jones
Christopher M Tegley
James P Edwards
Original Assignee
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ligand Pharm Inc filed Critical Ligand Pharm Inc
Publication of NO20015379D0 publication Critical patent/NO20015379D0/no
Publication of NO20015379L publication Critical patent/NO20015379L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20015379A 1999-05-04 2001-11-02 Indolinderivater som progesteronantagonister NO20015379L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18305899P 1999-05-04 1999-05-04
US09/552,632 US6391907B1 (en) 1999-05-04 2000-04-19 Indoline derivatives
PCT/US2000/011847 WO2000066556A1 (en) 1999-05-04 2000-05-01 Indoline derivatives as progesterone antagonists

Publications (2)

Publication Number Publication Date
NO20015379D0 true NO20015379D0 (no) 2001-11-02
NO20015379L NO20015379L (no) 2002-01-03

Family

ID=26878706

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015379A NO20015379L (no) 1999-05-04 2001-11-02 Indolinderivater som progesteronantagonister

Country Status (21)

Country Link
US (5) US6391907B1 (no)
EP (1) EP1175398B1 (no)
JP (1) JP2002543183A (no)
KR (1) KR20010114252A (no)
CN (1) CN1141295C (no)
AT (1) ATE366721T1 (no)
AU (1) AU4814100A (no)
BR (1) BR0010215A (no)
CA (1) CA2371638A1 (no)
CZ (1) CZ20013953A3 (no)
DE (1) DE60035496T2 (no)
DK (1) DK1175398T3 (no)
EA (1) EA200101177A1 (no)
ES (1) ES2290035T3 (no)
HU (1) HUP0200992A3 (no)
IL (1) IL146281A0 (no)
MX (1) MXPA01011298A (no)
NO (1) NO20015379L (no)
PL (1) PL351954A1 (no)
WO (1) WO2000066556A1 (no)
ZA (1) ZA200107631B (no)

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US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6417214B1 (en) * 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
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WO2002040036A1 (fr) * 2000-11-15 2002-05-23 Masao Sugamata Medicaments destines a la prevention ou au traitement de l'endometriose ou du myome uterin
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CL2003001544A1 (es) * 2002-10-11 2005-01-07 Ligand Pharm Inc Compuestos derivados de 5-cicloalquenil-5h-cromeno[3,4-f]quinolina de formula i, moduladores selectivos del receptor de progesterona; composicion farmaceutica; y su uso en el tratamiento de sangrado uterino disfuncional, dismenorrea, endometriosis, l
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GT200500186A (es) * 2004-07-07 2006-03-02 Regimenes anticonceptivos con antagonistas del receptor de progesterona y kits
GT200500185A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
GT200500183A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
JP4953457B2 (ja) * 2004-10-27 2012-06-13 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ プロゲステロン受容体モジュレーターとしてのピリジンイミダゾール及びアザ−インドール
US7414142B2 (en) * 2005-09-19 2008-08-19 Wyeth 5-aryl-indan-1-one oximes and analogs useful as progesterone receptor modulators
US7319152B2 (en) * 2005-09-19 2008-01-15 Wyeth 5-Aryl-indan-1-one and analogs useful as progesterone receptor modulators
US20070066628A1 (en) * 2005-09-19 2007-03-22 Wyeth 5-Aryl-indan-1-ol and analogs useful as progesterone receptor modulators
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KR20010114252A (ko) 2001-12-31
US7253203B2 (en) 2007-08-07
US20020086874A1 (en) 2002-07-04
CN1141295C (zh) 2004-03-10
DE60035496D1 (de) 2007-08-23
WO2000066556A1 (en) 2000-11-09
ZA200107631B (en) 2002-05-14
US7645761B2 (en) 2010-01-12
US20060160882A1 (en) 2006-07-20
NO20015379L (no) 2002-01-03
MXPA01011298A (es) 2003-07-14
AU4814100A (en) 2000-11-17
DE60035496T2 (de) 2008-03-13
IL146281A0 (en) 2002-07-25
PL351954A1 (en) 2003-07-14
EP1175398B1 (en) 2007-07-11
CA2371638A1 (en) 2000-11-09
EP1175398A1 (en) 2002-01-30
EA200101177A1 (ru) 2002-04-25
BR0010215A (pt) 2002-02-13
HUP0200992A2 (hu) 2002-07-29
ES2290035T3 (es) 2008-02-16
CN1350523A (zh) 2002-05-22
HUP0200992A3 (en) 2004-12-28
US6391907B1 (en) 2002-05-21
US7084168B2 (en) 2006-08-01
CZ20013953A3 (cs) 2002-06-12
DK1175398T3 (da) 2007-11-05
US20070259944A1 (en) 2007-11-08
US6608068B2 (en) 2003-08-19
US20030220388A1 (en) 2003-11-27
ATE366721T1 (de) 2007-08-15
JP2002543183A (ja) 2002-12-17

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