NO20013000D0 - Nye <beta>-amid- og <beta>-sulfonamidkarboksylsyrederivater, deres fremstilling og anvendelse som endotelinreseptorantagonister - Google Patents

Nye <beta>-amid- og <beta>-sulfonamidkarboksylsyrederivater, deres fremstilling og anvendelse som endotelinreseptorantagonister

Info

Publication number
NO20013000D0
NO20013000D0 NO20013000A NO20013000A NO20013000D0 NO 20013000 D0 NO20013000 D0 NO 20013000D0 NO 20013000 A NO20013000 A NO 20013000A NO 20013000 A NO20013000 A NO 20013000A NO 20013000 D0 NO20013000 D0 NO 20013000D0
Authority
NO
Norway
Prior art keywords
beta
amide
preparation
new
carboxylic acid
Prior art date
Application number
NO20013000A
Other languages
English (en)
Other versions
NO20013000L (no
Inventor
Wilhelm Amberg
Rolf Jansen
Georg Kettschau
Hartmut Riechers
Ernst Baumann
Stefan Hergenroeder
Manfred Raschack
Liliane Unger
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO20013000D0 publication Critical patent/NO20013000D0/no
Publication of NO20013000L publication Critical patent/NO20013000L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/14Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
    • C07D251/22Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to two ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/52Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20013000A 1998-12-18 2001-06-15 Nye <beta>-amid- og <beta>-sulfonamidkarboksylsyrederivater, deres fremstilling og anvendelse som endotelinreseptorantagonister NO20013000L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19858779A DE19858779A1 (de) 1998-12-18 1998-12-18 Neue ß-Amido und ß-Sulfonamidocarbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten
PCT/EP1999/009679 WO2000037450A1 (de) 1998-12-18 1999-12-09 NEUE β-AMIDO- UND β-SULFONAMIDOCARBONSÄUREDERIVATE, IHRE HERSTELLUNG UND VERWENDUNG ALS ENDOTHELIN-REZEPTORANTAGONISTEN

Publications (2)

Publication Number Publication Date
NO20013000D0 true NO20013000D0 (no) 2001-06-15
NO20013000L NO20013000L (no) 2001-08-15

Family

ID=7891778

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013000A NO20013000L (no) 1998-12-18 2001-06-15 Nye <beta>-amid- og <beta>-sulfonamidkarboksylsyrederivater, deres fremstilling og anvendelse som endotelinreseptorantagonister

Country Status (18)

Country Link
EP (1) EP1140867A1 (no)
JP (1) JP2002533330A (no)
KR (1) KR20010101279A (no)
CN (1) CN1334806A (no)
AR (1) AR023353A1 (no)
AU (1) AU3036400A (no)
BG (1) BG105618A (no)
BR (1) BR9916331A (no)
CA (1) CA2355251A1 (no)
CZ (1) CZ20012186A3 (no)
DE (1) DE19858779A1 (no)
HK (1) HK1042095A1 (no)
HU (1) HUP0201321A3 (no)
IL (1) IL143451A0 (no)
NO (1) NO20013000L (no)
SK (1) SK8682001A3 (no)
TR (1) TR200101780T2 (no)
WO (1) WO2000037450A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60113290D1 (de) * 2000-11-17 2005-10-13 Warner Lambert Co Behandlung von sexueller funktionsstörung mit bombesin rezeptor antagonisten
US7790770B2 (en) 2005-11-23 2010-09-07 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
EP2451786B1 (en) * 2009-07-10 2014-01-22 Cadila Healthcare Limited Improved process for the preparation of ambrisentan and novel intermediates thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8912700D0 (en) * 1989-06-02 1989-07-19 Shell Int Research Herbicidal compounds
DE4329911A1 (de) * 1993-09-04 1995-03-09 Basf Ag Substituierte Milchsäurederivate mit einem N-organischen Rest in beta-Position
EP0946524A1 (de) * 1996-12-18 1999-10-06 Basf Aktiengesellschaft Heterozyklische carbonsäurederivate, ihre herstellung und verwendung als endothelinrezeptorantagonisten
DE19726146A1 (de) * 1997-06-19 1998-12-24 Basf Ag Neue ß-Amino und ß-Azidopcarbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten

Also Published As

Publication number Publication date
NO20013000L (no) 2001-08-15
CA2355251A1 (en) 2000-06-29
HK1042095A1 (zh) 2002-08-02
HUP0201321A2 (hu) 2002-12-28
DE19858779A1 (de) 2000-06-21
TR200101780T2 (tr) 2001-11-21
CZ20012186A3 (cs) 2002-07-17
EP1140867A1 (de) 2001-10-10
WO2000037450A1 (de) 2000-06-29
BG105618A (en) 2002-01-31
CN1334806A (zh) 2002-02-06
AU3036400A (en) 2000-07-12
HUP0201321A3 (en) 2003-02-28
KR20010101279A (ko) 2001-11-14
JP2002533330A (ja) 2002-10-08
BR9916331A (pt) 2001-09-11
AR023353A1 (es) 2002-09-04
SK8682001A3 (en) 2002-08-06
IL143451A0 (en) 2002-04-21

Similar Documents

Publication Publication Date Title
NO20032699L (no) Nye sulfonamider og deres anvendelse som endothelinreseptorantagonister
NO991079L (no) Azinyloksy- og fenoksy-diaryl-karboksylsyre-derivater, deres fremstilling og deres anvendelse som blandede ETA/ETB-endotelin-reseptor-antagonister
DK1349839T3 (da) Phenylethenyl- eller phenylethinylderivater som glutamatraceptorantagonister
NO20013454D0 (no) 4-(Heterocyklylsulfonamido)-5-metoksy-6-(2-metoksyfenoksy)-2- fenyl- eller -pyridylpyrimidiner som endotelinreseptor-antagonister
DK1049689T3 (da) 4-(2-keto-1-benzimidazolinyl)piperidinderivater som ORL1-receptoragonister
NO20006029L (no) Pyrazolinderivater, deres fremstilling og anvendelse som legemidler
NO991761D0 (no) Nye piperidin-kotokarbonsyre-derivater, deres fremstilling og anvendelse
DK1004592T3 (da) Nye erythromycinderivater, deres fremstilling og deres anvendelse som medikamenter
NO20023146L (no) Substituerte fenyl-piperazinderivater, deres fremstilling og anvendelse
NO984714D0 (no) Nye karboksylsyre-derivater, deres fremstilling og anvendelse
NO20013709L (no) Nye N-triazolylmetyl-piperazinderivater som neurokininreseptor-antagonister
NO984713L (no) Nye karboksylsyre-derivater, deres fremstilling og anvendelse
NO20014224D0 (no) 4-heterocyklysulfonamidyl-6-metoksy-5-(2-metoksy-fenoksy)-2- pyridyl-pyrimidinderivater, fremstilling derav og anvendelse somendotelin reseptor antagonister
NO996268D0 (no) Nye &lt;beta&gt;-amino- og &lt;beta&gt;-azidokarboksylsyrederivater, fremstilling derav og anvendelse derav som endothelinreseptorantagonister
NO20013000D0 (no) Nye &lt;beta&gt;-amid- og &lt;beta&gt;-sulfonamidkarboksylsyrederivater, deres fremstilling og anvendelse som endotelinreseptorantagonister
NO992976L (no) Heterocykliske karboksylsyre-derivater, fremstilling og anvendelse derav som endothelinreseptor-antagonister
DK1390372T3 (da) 1-oxa-3,9-diaza-spiro &#39;5,5]undecan-2-on-derivater og anvendelse deraf som neurokininreceptorantagonist
NO20001077D0 (no) Nye karboksylsyrederivater, deres fremstilling og anvendelse som blandete ETA/ETB-endothelin-reseptorantagonister
NO20004075D0 (no) Substituerte pyrimidin-2-yloksy-karboksylsyrederivater, fremstilling av disse og deres anvendelse som endotelin- antagonister
NO20023188L (no) Nye heteroarylderivater, deres fremstilling og anvendelse
NO20020254L (no) Nye karboksylsyrederivater med 5,6-substituert pyrimidinring, fremstilling og anvendelse derav som endotelinreseptor-antagonister
DK1010689T3 (da) Substituerede cycloheptener, deres fremstilling og anvendelse
NO20004351D0 (no) Nye asymmetrisk substituerte karboksylsyrederivater, fremgangsmÕte for fremstilling av dem og deres anvendelse som blandete ETA/ETB-reseptorantagonister
ZA9810425B (en) Novel heterocyclically substituted Ó-hydroxycarboxylic acid derivatives, their preparation and use as endothelin receptor antagonists.
DK1235809T3 (da) Substituerede 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazociner og deres anvendelse som lægemidler

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application