NO20011117L - Anvendelse av benzensulfonyl(tio)ureaforbindelser for behandling og forebygging av dysfunksjoner i det autonomerenervesystem og anvendelse av benzensulfonyl(tio)ureaforbindelser ikombinasjon med <beta>-reseptor-blokkere - Google Patents

Anvendelse av benzensulfonyl(tio)ureaforbindelser for behandling og forebygging av dysfunksjoner i det autonomerenervesystem og anvendelse av benzensulfonyl(tio)ureaforbindelser ikombinasjon med <beta>-reseptor-blokkere

Info

Publication number
NO20011117L
NO20011117L NO20011117A NO20011117A NO20011117L NO 20011117 L NO20011117 L NO 20011117L NO 20011117 A NO20011117 A NO 20011117A NO 20011117 A NO20011117 A NO 20011117A NO 20011117 L NO20011117 L NO 20011117L
Authority
NO
Norway
Prior art keywords
benzenesulfonyl
thio
urea compounds
autonomer
dysfunctions
Prior art date
Application number
NO20011117A
Other languages
English (en)
Other versions
NO20011117D0 (no
NO330215B1 (no
Inventor
Klaus Wirth
Heinrich Christian Englert
Helmut Bohn
Heinz Goegelein
Holger Heitsch
Uwe Gerlach
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1998141534 external-priority patent/DE19841534A1/de
Priority claimed from DE1999101061 external-priority patent/DE19901061A1/de
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of NO20011117D0 publication Critical patent/NO20011117D0/no
Publication of NO20011117L publication Critical patent/NO20011117L/no
Publication of NO330215B1 publication Critical patent/NO330215B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C07C335/42Sulfonylthioureas; Sulfonylisothioureas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/58Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/54Silicon-containing compounds
    • C08K5/5406Silicon-containing compounds containing elements other than oxygen or nitrogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20011117A 1998-09-10 2001-03-05 Anvendelse av benzensulfonyl(tio)ureaforbindelser,produkt og farmasoytisk preparat omfattende ±n eller flere slike forbindelser NO330215B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1998141534 DE19841534A1 (de) 1998-09-10 1998-09-10 Verwendung von Benzolsulfonyl(thio)harnstoffen zur Behandlung und Prophylaxe von Dysfunktionen des autonomen Nervensystems und Verwendung von Benzolsulfonyl(thio)harnstoffen in Kombination mit Betarezeptoren-Blockern
DE1999101061 DE19901061A1 (de) 1999-01-14 1999-01-14 Verwendung von Benzolsulfonyl(thio)harnstoffen zur Behandlung von Prophylaxe von Dysfunktionen des autonomen Nervensystems und Verwendung von Benzolsulfonyl(thio)harnstoffen in Kombination mit Betarezeptoren-Blockern
PCT/EP1999/006450 WO2000015204A2 (en) 1998-09-10 1999-09-02 Use of benzenesulfonyl(thio)ureas for the treatment and prophylaxis of dysfunctions of the autonomous nervous system and use of benzenesulfonyl(thio)ureas in combination with beta-receptor blockers

Publications (3)

Publication Number Publication Date
NO20011117D0 NO20011117D0 (no) 2001-03-05
NO20011117L true NO20011117L (no) 2001-05-02
NO330215B1 NO330215B1 (no) 2011-03-07

Family

ID=26048790

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20011117A NO330215B1 (no) 1998-09-10 2001-03-05 Anvendelse av benzensulfonyl(tio)ureaforbindelser,produkt og farmasoytisk preparat omfattende ±n eller flere slike forbindelser

Country Status (27)

Country Link
US (1) US6414030B1 (no)
EP (1) EP1117409B1 (no)
JP (1) JP4733268B2 (no)
KR (1) KR100981592B1 (no)
CN (1) CN1195524C (no)
AR (1) AR020411A1 (no)
AT (1) ATE287718T1 (no)
AU (1) AU762832B2 (no)
BR (1) BR9913572A (no)
CA (1) CA2343009C (no)
CZ (1) CZ301165B6 (no)
DE (1) DE69923464T2 (no)
DK (1) DK1117409T3 (no)
ES (1) ES2235507T3 (no)
HK (1) HK1040187B (no)
HU (1) HU228988B1 (no)
ID (1) ID28854A (no)
IL (2) IL141414A0 (no)
MY (1) MY121798A (no)
NO (1) NO330215B1 (no)
NZ (1) NZ510424A (no)
PL (1) PL194986B1 (no)
PT (1) PT1117409E (no)
RU (1) RU2247562C2 (no)
TR (1) TR200100692T2 (no)
TW (1) TWI238817B (no)
WO (1) WO2000015204A2 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19917233A1 (de) * 1999-04-16 2000-10-19 Aventis Pharma Gmbh Kristalline Formen des Natriumsalzes des 5-Chlor-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonyl-phenyl)-ethyl)- benzamids
DE19923086A1 (de) 1999-05-20 2000-11-23 Aventis Pharma Gmbh Cinnamoylaminoalkyl-substituierte Benzolsulfonamidderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
US7620611B1 (en) * 1999-07-20 2009-11-17 Trilithic, Inc. Neural networks for ingress monitoring
DE10054481A1 (de) * 2000-11-03 2002-05-08 Aventis Pharma Gmbh Acylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10054482A1 (de) 2000-11-03 2002-05-08 Aventis Pharma Gmbh Heteroarylacryloylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10129704A1 (de) * 2001-06-22 2003-01-02 Aventis Pharma Gmbh Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
CN1330630C (zh) * 2004-03-10 2007-08-08 中国药科大学 新的磺酰(硫)脲衍生物、其制备方法及含有它们的药物组合物
DE102004061017A1 (de) 2004-12-18 2006-06-22 Sanofi-Aventis Deutschland Gmbh Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
MX2009012644A (es) * 2007-06-05 2009-12-10 Sanofi Aventis Derivados de di(hetero)arilciclohexano, su preparacion, su uso y composiciones farmaceuticas que los comprenden.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1185180B (de) * 1963-10-19 1965-01-14 Hoechst Ag Verfahren zur Herstellung von Benzolsulfonylharnstoffen
DE1518874C3 (de) * 1964-10-07 1975-03-13 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung
DE3009047A1 (de) 1980-03-08 1981-09-24 C.H. Boehringer Sohn, 6507 Ingelheim Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung
GB8716972D0 (en) * 1987-07-17 1987-08-26 Pfizer Ltd Treatment of cardiac arrhythmias
ES2098069T3 (es) 1993-02-23 1997-04-16 Hoechst Ag Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos.
DE19505397A1 (de) * 1995-02-17 1996-08-22 Hoechst Ag Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
WO1996028437A1 (en) 1995-03-10 1996-09-19 Hoechst Marion Roussel, Inc. Novel process for preparing 2,3-dihydro-benzofuranol derivatives
FR2746013B1 (fr) 1996-03-18 1998-05-29 Sanofi Sa Utilisation de composes antiarythmiques dans la prevention de la mortalite post infarctus

Also Published As

Publication number Publication date
HUP0103534A2 (hu) 2002-05-29
HK1040187B (zh) 2005-09-02
HK1040187A1 (en) 2002-05-31
IL141414A0 (en) 2002-03-10
AU762832B2 (en) 2003-07-03
HU228988B1 (hu) 2013-07-29
ID28854A (id) 2001-07-05
DE69923464T2 (de) 2006-05-11
RU2247562C2 (ru) 2005-03-10
BR9913572A (pt) 2001-05-22
PL347215A1 (en) 2002-03-25
PL194986B1 (pl) 2007-07-31
CZ2001858A3 (en) 2001-06-13
CN1195524C (zh) 2005-04-06
CA2343009C (en) 2011-03-15
WO2000015204A3 (en) 2000-07-13
TWI238817B (en) 2005-09-01
ES2235507T3 (es) 2005-07-01
CZ301165B6 (cs) 2009-11-25
KR100981592B1 (ko) 2010-09-13
NZ510424A (en) 2003-06-30
DK1117409T3 (da) 2005-05-30
NO20011117D0 (no) 2001-03-05
KR20010086396A (ko) 2001-09-10
AU5744499A (en) 2000-04-03
US6414030B1 (en) 2002-07-02
US20020082300A1 (en) 2002-06-27
PT1117409E (pt) 2005-04-29
ATE287718T1 (de) 2005-02-15
TR200100692T2 (tr) 2001-07-23
CN1319014A (zh) 2001-10-24
WO2000015204A2 (en) 2000-03-23
JP4733268B2 (ja) 2011-07-27
EP1117409A2 (en) 2001-07-25
NO330215B1 (no) 2011-03-07
MY121798A (en) 2006-02-28
CA2343009A1 (en) 2000-03-23
HUP0103534A3 (en) 2003-09-29
DE69923464D1 (de) 2005-03-03
JP2002524497A (ja) 2002-08-06
AR020411A1 (es) 2002-05-08
EP1117409B1 (en) 2005-01-26
IL141414A (en) 2006-07-05

Similar Documents

Publication Publication Date Title
NO963776D0 (no) (4,4-Difluorbut-3-enyltio)-substituerte heterosykliske eller karbocykliske ringforbindelser med disinfiserende virkning
HUP0004557A3 (en) Substituted imidazole derivatives having agonist-like activity at alpha 2b or 2b/2c adrenergic receptors and pharmaceuticals containing the same
EE200000706A (et) Bitsüklilised pürimidiinid ja bitsüklilised 3,4-dihüdropürimidiinid kui rakkude proliferatsiooni inhibiitorid
EE200100479A (et) Kasvuhormooni nõristitena kasulikud heterotsüklilised aromaatsed ühendid ja nende kasutamine
EP1066039A4 (en) SUBSTITUTED QUINAZOLINE AND THEIR ANALOGS AND USES
ATE273301T1 (de) Substituierte aza- und diazacycloheptan- und - cyclooctanverbindungen und deren verwendung
DE69909436D1 (de) Isothioncyanat-Tolane und sie enthaltende flüssigkristalline Gemische
DE69916742D1 (de) Polybenzoxazol-Harz und dessen Vorstufe
GB9809143D0 (en) Triazine compounds and their use
NO20011117L (no) Anvendelse av benzensulfonyl(tio)ureaforbindelser for behandling og forebygging av dysfunksjoner i det autonomerenervesystem og anvendelse av benzensulfonyl(tio)ureaforbindelser ikombinasjon med &lt;beta&gt;-reseptor-blokkere
DE60021507D1 (de) Uracilverbindungen und deren Verwendung
EE03682B1 (et) Asendatud bensimidasooli derivaadid, protsessid nende valmistamiseks ning nende kasutamine
NO20013409D0 (no) Anvendelse av pyrimidin-derivater for forhindring og behandling av cerebral ischemi
DE69917777D1 (de) Benzazol-verbindungen und ihre verwendung
ATE212346T1 (de) 3-substituierte tetrahydropyridopyrimidinon- derivate, ihre herstellung und verwendung
EE200000391A (et) Triasiiniühendid kesknärvisüsteemihäirete raviks
NO983089D0 (no) 2-amino-5,6-diklorbenzimidazol-derivater med antiviral aktivitet
DE59902692D1 (de) Phosphororganische verbindungen und ihre verwendung
DE59906907D1 (de) Phosphororganische verbindungen und ihre verwendung
ATE236905T1 (de) 4-oxo-3,5-dihydro-4h-pyridazino(4,5-b)indol-1- carboxamid-derivate, ihre herstellung und therapeutische verwendung
EP1137412A4 (en) SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THEIR THERAPEUTIC USE
DE60036885D1 (de) Succinimidverbindungen und deren verwendung
DE69707363T2 (de) 1,2,3-Benzothiadiazolderivate und ihre Verwendung als Mikrobizide
GB9824160D0 (en) Heterocyclic compounds and their therapeutic use
IL144145A0 (en) Utilisation of 2-substituted 1,2-benzisothiazole derivatives and 3-substituted tetrahydropyridopyrimidinone derivatives for the prophylaxis and therapy of cerebral ischaemia

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees