NO20000860L - Syklopeptidderivater som adhesjonsinhibitorer - Google Patents

Syklopeptidderivater som adhesjonsinhibitorer

Info

Publication number
NO20000860L
NO20000860L NO20000860A NO20000860A NO20000860L NO 20000860 L NO20000860 L NO 20000860L NO 20000860 A NO20000860 A NO 20000860A NO 20000860 A NO20000860 A NO 20000860A NO 20000860 L NO20000860 L NO 20000860L
Authority
NO
Norway
Prior art keywords
adhesion inhibitors
cyclopeptide derivatives
cyclopeptide
derivatives
arteriosclerosis
Prior art date
Application number
NO20000860A
Other languages
English (en)
Other versions
NO20000860D0 (no
Inventor
Guenter Hoelzemann
Simon Goodman
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20000860L publication Critical patent/NO20000860L/no
Publication of NO20000860D0 publication Critical patent/NO20000860D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Forbindelser med formel (I) hvor X, A, B og C har de i krav l angitte betydninger, samt deres salter, kan anvendes som integrininhibitorer, særlig til profylakse og behandling av sykdommer i blodomløpet, ved trombose, hjerteinfarkt, koronare hjertesykdommer, arteriosklerose, ved patologiske tilstander som underholdes eller propageres gjennom angiogenese og innen tumorterapien.
NO20000860A 1997-08-23 2000-02-22 Syklopeptidderivater som adhesjonsinhibitorer NO20000860D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19736772A DE19736772A1 (de) 1997-08-23 1997-08-23 Cyclopeptidderivate
PCT/EP1998/005161 WO1999010371A2 (de) 1997-08-23 1998-08-14 Cyclopeptidderivate als adhäsionsinhibitoren

Publications (2)

Publication Number Publication Date
NO20000860L true NO20000860L (no) 2000-02-22
NO20000860D0 NO20000860D0 (no) 2000-02-22

Family

ID=7839977

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20000860A NO20000860D0 (no) 1997-08-23 2000-02-22 Syklopeptidderivater som adhesjonsinhibitorer

Country Status (18)

Country Link
EP (1) EP1007545A2 (no)
JP (1) JP2001514186A (no)
KR (1) KR20010022828A (no)
CN (1) CN1267306A (no)
AR (1) AR013650A1 (no)
AU (1) AU734829B2 (no)
BR (1) BR9811992A (no)
CA (1) CA2301182A1 (no)
DE (1) DE19736772A1 (no)
HU (1) HUP0003500A3 (no)
ID (1) ID23952A (no)
NO (1) NO20000860D0 (no)
PL (1) PL341090A1 (no)
RU (1) RU2200166C2 (no)
SK (1) SK2132000A3 (no)
TW (1) TW477793B (no)
WO (1) WO1999010371A2 (no)
ZA (1) ZA987558B (no)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA43823C2 (uk) * 1992-07-06 2002-01-15 Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН
DE4310643A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
DE4415310A1 (de) * 1994-04-30 1995-11-02 Merck Patent Gmbh Cyclopeptide
JPH07316193A (ja) * 1994-05-24 1995-12-05 Asahi Glass Co Ltd ペプチド誘導体およびその用途

Also Published As

Publication number Publication date
WO1999010371A2 (de) 1999-03-04
CA2301182A1 (en) 1999-03-04
EP1007545A2 (de) 2000-06-14
JP2001514186A (ja) 2001-09-11
AR013650A1 (es) 2001-01-10
KR20010022828A (ko) 2001-03-26
HUP0003500A3 (en) 2001-12-28
ZA987558B (en) 1999-02-23
DE19736772A1 (de) 1999-02-25
ID23952A (id) 2000-06-08
PL341090A1 (en) 2001-03-26
WO1999010371A3 (de) 1999-05-27
RU2200166C2 (ru) 2003-03-10
CN1267306A (zh) 2000-09-20
NO20000860D0 (no) 2000-02-22
SK2132000A3 (en) 2000-09-12
AU734829B2 (en) 2001-06-21
AU9531998A (en) 1999-03-16
HUP0003500A2 (hu) 2001-02-28
TW477793B (en) 2002-03-01
BR9811992A (pt) 2000-09-05

Similar Documents

Publication Publication Date Title
NO20010203L (no) Diacylhydrazinderivater som integrininhibitorer
TW372232B (en) Phenylalanine derivatives
NO986090L (no) Fenylalaninderivater som integrininhibitorer
NO991951L (no) Tienopyrimidiner med fosfodiesterase V-inhiberende virkning
NO20000841L (no) N-Aroylfenylalanin-derivater
CA2280727A1 (en) Bicyclic amino acids
NO20021281L (no) Vaskul¶r beleggingssammensetning
MY130661A (en) New oxabispidine compounds useful in the treatment of cardiac arrhythmias
WO2000071516A3 (en) INHIBITORS OF FACTOR Xa
SE8304737D0 (sv) Karbostyrilderivat
DE60137635D1 (de) Verwendung von allopurinol zur behandlung von bluthochdruck
NO983991L (no) Serin-protease-inhibitorer
NO20016201L (no) Tienopyrimidiner som fosfodiesteraseinhibitorer
MY133785A (en) Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias
WO2003059258A3 (en) Compositions and methods for treating heart failure
CA2348391A1 (en) Chromenone and chromanone derivatives as integrin inhibitors
DE60001555D1 (de) Wässrige lösung zum konservieren von gewebe und organen
NO20000016L (no) Sykliske azapeptider med angiogen virkning
BR9917495A (pt) Derivados o ácido betulìnico tendo atividade antiangiogênica, processos para produzir tais derivados e sua utilização para o tratamento de antiogênese associada a tumores
WO2003059265A3 (en) Compositions and methods for treating heart failure
DE60138189D1 (de) Eine neue verwendung von deferiprone
RU96112829A (ru) Способ лечения ишемической болезни сердца
ITTO950099A0 (it) Catetere, particolarmente per il trattamento di aritmie cardiache.
NO20000860L (no) Syklopeptidderivater som adhesjonsinhibitorer
NO20020131L (no) Diacylhydrazinderivater