NO180308C - Fremgangsmåte for fremstilling av en tilnærmet ikke-racemisk form av furo (3,4-c) pyridin-derivater - Google Patents

Fremgangsmåte for fremstilling av en tilnærmet ikke-racemisk form av furo (3,4-c) pyridin-derivater

Info

Publication number: NO180308C
Authority: NO; Norway
Prior art keywords: furo; preparation; pyridine derivatives; racemic form; approximate non
Prior art date: 1990-05-14

Application number

NO911852A

Other languages

English (en)

Other versions

NO911852D0 (no

NO911852L (no

NO180308B (no

Inventor

Charles R Eck

Paul C Ahrens

Rae Marie Saltzstein

Original Assignee

Sod Conseils Rech Applic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-14

Filing date

1991-05-13

Publication date

1997-03-26

1991-05-13 Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic

1991-05-13 Publication of NO911852D0 publication Critical patent/NO911852D0/no

1991-11-15 Publication of NO911852L publication Critical patent/NO911852L/no

1996-12-16 Publication of NO180308B publication Critical patent/NO180308B/no

1997-03-26 Publication of NO180308C publication Critical patent/NO180308C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO911852A 1990-05-14 1991-05-13 Fremgangsmåte for fremstilling av en tilnærmet ikke-racemisk form av furo (3,4-c) pyridin-derivater NO180308C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/523,238 US5130252A (en)	1990-05-14	1990-05-14	Resolution of furopyridine enantiomers and synthetic precursors thereof

Publications (4)

Publication Number	Publication Date
NO911852D0 NO911852D0 (no)	1991-05-13
NO911852L NO911852L (no)	1991-11-15
NO180308B NO180308B (no)	1996-12-16
NO180308C true NO180308C (no)	1997-03-26

Family

ID=24084213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO911852A NO180308C (no)	1990-05-14	1991-05-13	Fremgangsmåte for fremstilling av en tilnærmet ikke-racemisk form av furo (3,4-c) pyridin-derivater

Country Status (32)

Country	Link
US (1)	US5130252A (no)
JP (1)	JPH05117277A (no)
KR (1)	KR910020015A (no)
AR (1)	AR247762A1 (no)
AT (1)	AT400445B (no)
AU (1)	AU642368B2 (no)
BE (1)	BE1007016A3 (no)
CA (1)	CA2042421C (no)
CH (1)	CH682488A5 (no)
DE (1)	DE4115681C2 (no)
DK (1)	DK88991A (no)
DZ (1)	DZ1499A1 (no)
ES (1)	ES2033574B1 (no)
FI (1)	FI97807C (no)
FR (1)	FR2661919B1 (no)
GB (1)	GB2244056B (no)
GR (1)	GR1001593B (no)
HK (1)	HK131993A (no)
IE (1)	IE65891B1 (no)
IT (1)	IT1248743B (no)
LU (1)	LU87935A1 (no)
MA (1)	MA22154A1 (no)
MY (1)	MY107567A (no)
NL (1)	NL194615C (no)
NO (1)	NO180308C (no)
NZ (1)	NZ238009A (no)
OA (1)	OA09352A (no)
PT (1)	PT97657B (no)
SE (1)	SE510808C2 (no)
TN (1)	TNSN91035A1 (no)
TW (1)	TW226998B (no)
ZA (1)	ZA913461B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0221494D0 (en) *	2002-09-16	2002-10-23	Generics Uk Ltd	Novel processes for the preparation of 1.3-dihydro-6-methylfuro (3,4-c) pyndin derivatives
US20110251396A1 (en) *	2003-07-17	2011-10-13	Gilead Sciences, Inc.	Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
GB2419529B (en) *	2003-07-17	2008-01-09	Cotherix Inc	Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome
US20060089374A1 (en) *	2003-07-17	2006-04-27	Glenn Cornett	Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
CA2537180A1 (en) *	2003-08-29	2005-03-10	Cotherix, Inc.	Cicletanine in combination with oral antidiabetic and/or blood lipid-lowering agents as a combination therapy for diabetes and metabolic syndrome
US20060154959A1 (en) *	2005-01-13	2006-07-13	Navitas Pharma	Combination therapies of cicletanine and carvedilol
US7375112B2 (en) *	2005-01-05	2008-05-20	Medicure International Inc.	Compounds and methods for regulating triglyceride levels
US20070141174A1 (en) *	2005-01-13	2007-06-21	Navitas Pharma, Inc.	Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension
US20080096915A1 (en) *	2005-01-13	2008-04-24	Greenberg Traurig LLP	Compositions for the treatment of metabolic disorders
US20070105817A1 (en) *	2005-11-09	2007-05-10	Jim Page	Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension
CA2674367A1 (en) *	2007-01-03	2008-07-17	Glenn V. Cornett	Cicletanine and pkc inhibitors in the treatment of pulmonary and cardiac disorders
WO2011053519A1 (en) *	2009-10-29	2011-05-05	Merck Sharp & Dohme Corp.	Diuretics

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN156817B (no) *	1981-02-10	1985-11-09	Scras
US4985365A (en) *	1981-11-28	1991-01-15	Sumitomo Chemical Company, Ltd.	Process for producing optically active benzyl alcohol compound
DE3378834D1 (en) *	1982-08-13	1989-02-09	Kanegafuchi Chemical Ind	Process for production of optically active oxazolidinone derivative
IN160104B (no) *	1983-04-05	1987-06-27	Scras
JPS59216590A (ja) *	1983-05-24	1984-12-06	Ube Ind Ltd	光学活性フエニルプロパルギルアルコ−ル誘導体の製法
GB8327817D0 (en) *	1983-10-18	1983-11-16	Scras	4-halo-furo-(3 4-c)-pyridine derivatives
GB8330517D0 (en) *	1983-11-16	1983-12-21	Scras	6-vinyl-furo-(3,4-c)pyridine derivatives
GB8330658D0 (en) *	1983-11-17	1983-12-29	Scras	7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives
GB8402740D0 (en) *	1984-02-02	1984-03-07	Scras	Furo-(3 4-c)-pyridine derivatives
JPS60224494A (ja) *	1984-04-24	1985-11-08	Nissan Chem Ind Ltd	α−メチルベンジルアルコ−ル類の光学分割法
GB8414559D0 (en) *	1984-06-07	1984-07-11	Scras	Pyridine derivatives
GB8427218D0 (en) *	1984-10-27	1984-12-05	Scras	Pyridine derivatives
JPS61289899A (ja) *	1985-06-18	1986-12-19	Kanegafuchi Chem Ind Co Ltd	光学活性２−ハロ−１−フエニルエタノ−ルおよびそのエステルの製造法
US4916074A (en) *	1986-10-30	1990-04-10	Chisso Corporation	Process for producing optically active compounds
JP2691986B2 (ja) *	1987-08-28	1997-12-17	チッソ株式会社	ピリジン骨格を有する光学活性化合物の製造法
DE3737335A1 (de) *	1987-11-04	1989-05-18	Basf Ag	Verfahren zur herstellung eines biokatalysators und dessen verwendung zur razematspaltung
DE3990349T1 (de) *	1988-04-06	1990-04-26	Scras	Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen
GB8808001D0 (en) *	1988-04-06	1988-05-05	Scras	Stereospecific preparative process for furol(3,4-c)pyridine derivatives
NL8801311A (nl) *	1988-05-20	1989-12-18	Stamicarbon	Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem.
GB8907480D0 (en) *	1989-04-03	1989-05-17	Scaras Societe De Conseils De	Separation of insomers of furo(3,4-c)pyridine derivatives
GB8917168D0 (en) *	1989-07-27	1989-09-13	Scras	Asymmetric synthesis of furo(3,4-c)pyridine derivatives

1990
- 1990-05-14 US US07/523,238 patent/US5130252A/en not_active Expired - Lifetime
1991
- 1991-04-24 GR GR910100180A patent/GR1001593B/el not_active IP Right Cessation
- 1991-04-29 AU AU76200/91A patent/AU642368B2/en not_active Ceased
- 1991-05-01 NZ NZ238009A patent/NZ238009A/en unknown
- 1991-05-01 NL NL9100749A patent/NL194615C/nl not_active IP Right Cessation
- 1991-05-02 CH CH1318/91A patent/CH682488A5/fr not_active IP Right Cessation
- 1991-05-07 ZA ZA913461A patent/ZA913461B/xx unknown
- 1991-05-07 GB GB9109810A patent/GB2244056B/en not_active Expired - Fee Related
- 1991-05-08 IT ITMI911255A patent/IT1248743B/it active IP Right Grant
- 1991-05-08 MY MYPI91000775A patent/MY107567A/en unknown
- 1991-05-08 DZ DZ910055A patent/DZ1499A1/fr active
- 1991-05-10 AR AR91319663A patent/AR247762A1/es active
- 1991-05-13 NO NO911852A patent/NO180308C/no not_active IP Right Cessation
- 1991-05-13 DK DK088991A patent/DK88991A/da not_active Application Discontinuation
- 1991-05-13 ES ES9101157A patent/ES2033574B1/es not_active Expired - Fee Related
- 1991-05-13 MA MA22424A patent/MA22154A1/fr unknown
- 1991-05-13 FI FI912315A patent/FI97807C/fi active
- 1991-05-13 TN TNTNSN91035A patent/TNSN91035A1/fr unknown
- 1991-05-13 AT AT0098291A patent/AT400445B/de not_active IP Right Cessation
- 1991-05-13 IE IE162891A patent/IE65891B1/en not_active IP Right Cessation
- 1991-05-13 CA CA002042421A patent/CA2042421C/en not_active Expired - Fee Related
- 1991-05-13 BE BE9100441A patent/BE1007016A3/fr not_active IP Right Cessation
- 1991-05-13 SE SE9101431A patent/SE510808C2/sv not_active IP Right Cessation
- 1991-05-13 KR KR1019910007684A patent/KR910020015A/ko not_active Application Discontinuation
- 1991-05-14 JP JP3109203A patent/JPH05117277A/ja active Pending
- 1991-05-14 PT PT97657A patent/PT97657B/pt not_active IP Right Cessation
- 1991-05-14 FR FR9105766A patent/FR2661919B1/fr not_active Expired - Lifetime
- 1991-05-14 DE DE4115681A patent/DE4115681C2/de not_active Expired - Lifetime
- 1991-05-14 LU LU87935A patent/LU87935A1/fr unknown
- 1991-05-14 OA OA59998A patent/OA09352A/xx unknown
- 1991-07-09 TW TW080105317A patent/TW226998B/zh active
1993
- 1993-12-02 HK HK1319/93A patent/HK131993A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT97657A (pt)	1992-02-28
GR1001593B (el)	1993-03-31
LU87935A1 (fr)	1992-03-03
ES2033574A1 (es)	1993-03-16
OA09352A (fr)	1992-09-15
SE9101431D0 (sv)	1991-05-13
ATA98291A (de)	1995-05-15
ITMI911255A1 (it)	1992-11-08
NL9100749A (nl)	1991-12-02
ZA913461B (en)	1992-02-26
DK88991A (da)	1991-11-15
DE4115681C2 (de)	2003-10-30
FI97807B (fi)	1996-11-15
ES2033574B1 (es)	1994-02-01
NO911852D0 (no)	1991-05-13
CA2042421C (en)	2000-08-22
GR910100180A (en)	1992-07-30
IE65891B1 (en)	1995-11-29
IE911628A1 (en)	1991-11-20
NL194615B (nl)	2002-05-01
CH682488A5 (fr)	1993-09-30
GB2244056A (en)	1991-11-20
FI912315A (fi)	1991-11-15
FI912315A0 (fi)	1991-05-13
HK131993A (en)	1993-12-10
CA2042421A1 (en)	1991-11-15
JPH05117277A (ja)	1993-05-14
GB2244056B (en)	1993-08-11
NL194615C (nl)	2002-09-03
ITMI911255A0 (it)	1991-05-08
FR2661919B1 (fr)	1994-12-30
FI97807C (fi)	1997-02-25
NO911852L (no)	1991-11-15
NZ238009A (en)	1992-11-25
AU7620091A (en)	1991-11-14
TW226998B (no)	1994-07-21
SE510808C2 (sv)	1999-06-28
SE9101431L (sv)	1991-11-15
TNSN91035A1 (fr)	1992-10-25
DZ1499A1 (fr)	2004-09-13
GB9109810D0 (en)	1991-06-26
IT1248743B (it)	1995-01-26
KR910020015A (ko)	1991-12-19
NO180308B (no)	1996-12-16
MY107567A (en)	1996-04-30
PT97657B (pt)	1998-09-30
BE1007016A3 (fr)	1995-02-21
AR247762A1 (es)	1995-03-31
AT400445B (de)	1995-12-27
US5130252A (en)	1992-07-14
DE4115681A1 (de)	1991-11-21
AU642368B2 (en)	1993-10-14
MA22154A1 (fr)	1991-12-31
DK88991D0 (da)	1991-05-13
FR2661919A1 (fr)	1991-11-15

Legal Events

Date	Code	Title	Description
2003-12-29	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN NOVEMBER 2003

Publication	Publication Date	Title
NO820253L (no)	1982-08-11	Fremgangsmaate for fremstilling av furo-(3,4-c)pyridin-derivater
NO904987D0 (no)	1990-11-16	Fremgangsmaate for fremstilling av indolderivater.
NO841322L (no)	1984-10-08	Fremgangsmaate for fremstilling av furo (3,4-c)-pyridin-derivater
NO850399L (no)	1985-08-05	Fremgangsmaate for fremstilling av 6-substituerte furo (3,4-c)pyridin-derivater
NO180308C (no)	1997-03-26	Fremgangsmåte for fremstilling av en tilnærmet ikke-racemisk form av furo (3,4-c) pyridin-derivater
NO903431D0 (no)	1990-08-03	Fremgangsmaate for fremstilling av kromanderivater.
NO903275L (no)	1991-01-25	Fremgangsmaate for fremstilling av kromanderivater.
NO905377D0 (no)	1990-12-12	Fremgangsmaate for fremstilling av glycerolderivater.
AR229519A1 (es)	1983-09-15	Procedimiento de preparacion de derivados de 2,3-dihidro-9-fenil-1h-pirazolo(1,2-a)-indazolio
NO903043D0 (no)	1990-07-06	Fremgangsmaate for fremstilling av kromanderivater.
NO903207L (no)	1991-01-21	Fremgangsmaate for fremstilling av halogenaminoaromatiske derivater.
NO179517C (no)	1996-10-23	Fremgangsmåte for fremstilling av 8-klorkinolonderivater
NO845038L (no)	1985-06-17	Fremgangsmaate for fremstilling av 4,5,6,7-tetrahydrotiazolo(5,4-c)pyridin-derivater
ES536814A0 (es)	1985-08-01	Procedimiento de preparacion de nuevos derivados de 1, 3-dihidro-6-metil-7-hidroxi-furo-(3, 4-c)-piridina
NO902762D0 (no)	1990-06-21	Fremgangsmaate for fremstilling av 5-fenyl-2-furan derivater.
NO900969D0 (no)	1990-03-01	Fremgangsmaate for fremstilling av anilin-derivat.
NO174150C (no)	1994-03-23	Fremgangsmåte for fremstilling av furo-(3,4-c)pyridin-derivater i ikke-racemisk form
NO905047D0 (no)	1990-11-21	Fremgangsmaate for fremstilling av selenofenderivater.
SG125793G (en)	1994-02-25	Preparation of non-racemic furo (3,4-c) pyridine derivatives
NO177305C (no)	1995-08-23	Fremgangsmåte for fremstilling av 3-substituerte-2-oksindol-derivater
NO180301C (no)	1997-03-26	Fremgangsmåte for fremstilling av azaspiroalkanderivater
NO922254D0 (no)	1992-06-09	Framgangsmaate for framstilling av 1,5-benzotiazepinderivater
NO172286C (no)	1993-06-30	Framgangsmaate for framstilling av 1,5-benzotiazepinderivater
FI954169A0 (fi)	1995-09-06	Menetelmä 3-substituoitujen 2-oksoindolijohdannaisten valmistamiseksi
NO904362L (no)	1991-04-10	Fremgangsmaate for fremstilling av kromanderivater.